Disulfide-centered star-shaped polypeptide-PEO block copolymers for reduction-triggered drug release

Ligand-Directed Reduction-Sensitive Shell-Sheddable Biodegradable Micelles Actively Deliver Doxorubicin into the Nuclei of Target Cancer Cells

(2013) Yinan Zhong et al.   BIOMACROMOLECULES

Synthesis of Hyperbranched Polypeptide and PEO Block Copolymer by Consecutive Thiol-Yne Chemistry

(2013) Xiao Chang et al.   BIOMACROMOLECULES

Synthetic Glycopolypeptides as Biomimetic Analogues of Natural Glycoproteins

(2013) Colin Bonduelle et al.   BIOMACROMOLECULES

Cellular uptake, intracellular trafficking, and antitumor efficacy of doxorubicin-loaded reduction-sensitive micelles

(2013) Can Cui et al.   BIOMATERIALS

Tunable assembly of amphiphilic rod–coil block copolymers in solution

(2013) Jie Zhang et al.   CHEMICAL SOCIETY REVIEWS

Photo-control of biological systems with azobenzene polymers

(2013) Alexis Goulet-Hanssens et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Stimuli-responsive nanocarriers for drug delivery

(2013) Simona Mura et al.   NATURE MATERIALS

Photochemical mechanisms of light-triggered release from nanocarriers

(2012) Nadezda Fomina et al.   ADVANCED DRUG DELIVERY REVIEWS

Stimuli-responsive polymeric nanocarriers for the controlled transport of active compounds: Concepts and applications

(2012) Emanuel Fleige et al.   ADVANCED DRUG DELIVERY REVIEWS

Photoresponsive Poly(S-(o-nitrobenzyl)-l-cysteine)-b-PEO from a l-Cysteine N-Carboxyanhydride Monomer: Synthesis, Self-Assembly, and Phototriggered Drug Release

(2012) Gang Liu et al.   BIOMACROMOLECULES

Recent advances in stimuli-responsive degradable block copolymer micelles: synthesis and controlled drug delivery applications

(2012) Qian Zhang et al.   CHEMICAL COMMUNICATIONS

Reduction- and thermo-sensitive star polypeptide micelles and hydrogels for on-demand drug delivery

(2012) Dong-Lin Liu et al.   CHEMICAL COMMUNICATIONS

Design of polymeric nanoparticles for biomedical delivery applications

(2012) Mahmoud Elsabahy et al.   CHEMICAL SOCIETY REVIEWS

Challenges in design of translational nanocarriers

(2012) Qihang Sun et al.   JOURNAL OF CONTROLLED RELEASE

Intracellular microenvironment responsive PEGylated polypeptide nanogels with ionizable cores for efficient doxorubicin loading and triggered release

(2012) Fenghua Shi et al.   JOURNAL OF MATERIALS CHEMISTRY

Synthesis and properties of monocleavable amphiphilic comblike copolymers with alternating PEG and PCL grafts

(2012) Shixian Li et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Bioreducible and core-crosslinked hybrid micelles from trimethoxysilyl-ended poly(ε-caprolactone)-S-S-poly(ethylene oxide) block copolymers: Thiol-ene click synthesis and properties

(2012) Yu-Jing Wang et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Triple Click Reaction Strategy for Macromolecular Diversity

(2012) Umit Tunca   MACROMOLECULAR RAPID COMMUNICATIONS

Block Copolypeptides Prepared by N-Carboxyanhydride Ring-Opening Polymerization

(2012) Gijs J. M. Habraken et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Linear–dendritic biodegradable block copolymers: from synthesis to application in bionanotechnology

(2012) Chang-Ming Dong et al.   Polymer Chemistry

Design and development of polymeric micelles with cleavable links for intracellular drug delivery

(2012) Hua Wei et al.   PROGRESS IN POLYMER SCIENCE

Biocompatible reduction-responsive polypeptide micelles as nanocarriers for enhanced chemotherapy efficacy in vitro

(2012) Jianxun Ding et al.   Journal of Materials Chemistry B

Multifunctional Nanogels for siRNA Delivery

(2011) Michael H. Smith et al.   ACCOUNTS OF CHEMICAL RESEARCH

Self-Assembled Targeted Nanoparticles: Evolution of Technologies and Bench to Bedside Translation

(2011) Jinjun Shi et al.   ACCOUNTS OF CHEMICAL RESEARCH

The Importance of Chemistry in Creating Well-Defined Nanoscopic Embedded Therapeutics: Devices Capable of the Dual Functions of Imaging and Therapy

(2011) Andreas M. Nyström et al.   ACCOUNTS OF CHEMICAL RESEARCH

Supramolecular Nanodevices: From Design Validation to Theranostic Nanomedicine

(2011) Horacio Cabral et al.   ACCOUNTS OF CHEMICAL RESEARCH

Molecular Self-Assembly of a Homopolymer: An Alternative To Fabricate Drug-Delivery Platforms for Cancer Therapy

(2011) Jinyao Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Thermoresponsive Polypeptides from Pegylated Poly-l-glutamates

(2011) Chongyi Chen et al.   BIOMACROMOLECULES

Bioreducible micelles and hydrogels with tunable properties from multi-armed biodegradable copolymers

(2011) Lin Sun et al.   CHEMICAL COMMUNICATIONS

Biologically Active Polymersomes from Amphiphilic Glycopeptides

(2011) Jin Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dendritic and Hyperbranched Polymers from Macromolecular Units: Elegant Approaches to the Synthesis of Functional Polymers

(2011) Dominik Konkolewicz et al.   MACROMOLECULES

Luminescent Hyperbranched Polymers: Combining Thiol-Yne Chemistry with Gold-Mediated C−H Bond Activation

(2011) Dominik Konkolewicz et al.   ORGANOMETALLICS

Versatile synthesis of temperature-sensitive polypeptides by click grafting of oligo(ethylene glycol)

(2011) Yilong Cheng et al.   Polymer Chemistry

FDA-approved poly(ethylene glycol)–protein conjugate drugs

(2011) Steevens N. S. Alconcel et al.   Polymer Chemistry

Complex polymer architectures via RAFT polymerization: From fundamental process to extending the scope using click chemistry and nature's building blocks

(2011) Andrew Gregory et al.   PROGRESS IN POLYMER SCIENCE

Biodegradable synthetic polymers: Preparation, functionalization and biomedical application

(2011) Huayu Tian et al.   PROGRESS IN POLYMER SCIENCE

Ionic polypeptides with unusual helical stability

(2011) Hua Lu et al.   Nature Communications

Dual Stimuli-Responsive Supramolecular Polypeptide-Based Hydrogel and Reverse Micellar Hydrogel Mediated by Host-Guest Chemistry

(2010) Yi Chen et al.   ADVANCED FUNCTIONAL MATERIALS

Thiol-Yne Chemistry: A Powerful Tool for Creating Highly Functional Materials

(2010) Richard Hoogenboom   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Thiol-Ene Click Chemistry

(2010) Charles E. Hoyle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hyperbranched alternating block copolymers using thiol–yne chemistry: materials with tuneable properties

(2010) Dominik Konkolewicz et al.   CHEMICAL COMMUNICATIONS

pH-Sensitive Supramolecular Polypeptide-Based Micelles and Reverse Micelles Mediated by Hydrogen-Bonding Interactions or Host−Guest Chemistry: Characterization and In Vitro Controlled Drug Release

(2010) Yi Chen et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Versatile Strategy for the Synthesis of Hyperbranched Poly(ε-caprolactone)s and Polypseudorotaxanes Thereof

(2010) Wei Liu et al.   MACROMOLECULES

Reaction Rates and Mechanisms for Radical, Photoinitated Addition of Thiols to Alkynes, and Implications for Thiol−Yne Photopolymerizations and Click Reactions

(2010) Benjamin D. Fairbanks et al.   MACROMOLECULES

Doxorubicin conjugated, crosslinked, PEGylated particles prepared via one-pot thiol-ene modification of a homopolymer scaffold: synthesis and in vitro evaluation

(2010) Lingjiun Wong et al.   Polymer Chemistry

Thiol–yne ‘click’ chemistry as a route to functional lipid mimetics

(2010) Sandeep S. Naik et al.   Polymer Chemistry

An overview of protein–polymer particles

(2010) Cyrille Boyer et al.   Soft Matter

Intelligent polymeric micelles from functional poly(ethylene glycol)-poly(amino acid) block copolymers

(2009) Younsoo Bae et al.   ADVANCED DRUG DELIVERY REVIEWS

Versatile Strategy for the Synthesis of Dendronlike Polypeptide/Linear Poly(ε-caprolactone) Block Copolymers via Click Chemistry

(2009) Chong Hua et al.   BIOMACROMOLECULES

Stimuli-Responsive Polymersomes for Programmed Drug Delivery

(2009) Fenghua Meng et al.   BIOMACROMOLECULES

Efficient synthesis of dendrimers via a thiol–yne and esterification process and their potential application in the delivery of platinum anti-cancer drugs

(2009) Gaojian Chen et al.   CHEMICAL COMMUNICATIONS

Applications of Orthogonal “Click” Chemistries in the Synthesis of Functional Soft Materials

(2009) Rhiannon K. Iha et al.   CHEMICAL REVIEWS

Sequential Phosphine-Catalyzed, Nucleophilic Thiol−Ene/Radical-Mediated Thiol−Yne Reactions and the Facile Orthogonal Synthesis of Polyfunctional Materials

(2009) Justin W. Chan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hyperbranched Polymers by Thiol−Yne Chemistry: From Small Molecules to Functional Polymers

(2009) Dominik Konkolewicz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Secondary Structure-Induced Micro- and Macrophase Separation in Rod-Coil Polypeptide Diblock, Triblock, and Star-Block Copolymers

(2009) Antoni Sánchez-Ferrer et al.   MACROMOLECULES

Thiol-ene “click” reactions and recent applications in polymer and materials synthesis

(2009) Andrew B. Lowe   Polymer Chemistry

Cu-Catalyzed Azide−Alkyne Cycloaddition

(2008) Morten Meldal et al.   CHEMICAL REVIEWS

PEG-Detachable Polyplex Micelles Based on Disulfide-Linked Block Catiomers as Bioresponsive Nonviral Gene Vectors

(2008) Seiji Takae et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dendron-like Polypeptide/Linear Poly(ethylene oxide) Biohybrids with Both Asymmetrical and Symmetrical Topologies Synthesized via the Combination of Click Chemistry and Ring-Opening Polymerization

(2008) Song-Ming Peng et al.   MACROMOLECULES

Thiol−Yne Photopolymerizations: Novel Mechanism, Kinetics, and Step-Growth Formation of Highly Cross-Linked Networks

(2008) Benjamin D. Fairbanks et al.   MACROMOLECULES

Dendritic and hyperbranched polyamides

(2008) Markus Scholl et al.   PROGRESS IN POLYMER SCIENCE