Article
Chemistry, Physical
Mario R. P. da Silva, Robert S. Matos, Michael D. S. Monteiro, Samuel B. Santos, Henrique D. F. Filho, George R. S. Andrade, Marco Salerno, Luis E. Almeida
Summary: A new type of PHB-based composite film containing PEG, ALG-e, and polymeric additives loaded with AgNPs was prepared by a conventional casting method. The film exhibited good thermal performance, water vapor permeability, and antimicrobial activity, making it suitable for skin wound treatment.
Article
Engineering, Biomedical
Alessondra T. Speidel, Phillip R. A. Chivers, Christopher S. Wood, Derrick A. Roberts, Ines P. Correia, April S. Caravaca, Yu Kiu Victor Chan, Catherine S. Hansel, Johannes Heimgaertner, Eliane Mueller, Jill Ziesmer, Georgios A. Sotiriou, Peder S. Olofsson, Molly M. Stevens
Summary: Polyurethane-based hydrogels with tunable mechanical properties and nonfouling characteristics have been synthesized and tested for various applications. The gels show excellent biocompatibility and reduced cellular adhesion compared to a mechanically matched formula. Preliminary implant studies indicate a mild foreign body response. This method offers a simplified platform for fabricating soft PU-based biomaterials.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Polymer Science
Qi Xu, Jianwei Lin, Guichang Jiang
Summary: This paper explores the use of environmentally friendly and renewable bio-based materials to prepare polyurethane. Epoxy soybean oil and polyethylene glycol were used to prepare soybean oil-based polyester polyols, which were then reacted with isophorone diisocyanate to synthesize soybean oil-based polyurethane. The properties of the polyurethane films were adjusted by changing the reaction conditions, and the results show that the properties of the polyurethane films change accordingly.
Article
Polymer Science
Dong-Hua Xu, Fang Liu, Ge Pan, Zhi-Gang Zhao, Xue Yang, Heng-Chong Shi, Shi-Fang Luan
Summary: The study explored the effects of water on the structure and mechanical properties of TPU blends, observing both softening and hardening phenomena in wet samples compared to dry ones. The changes were attributed to alterations in the interface structure between hard and soft domains in TPU, involving plasticization of free water, weakening of original hydrogen bonds, and formation of new hydrogen bonds by carbonyl groups in TPU and water.
Article
Polymer Science
Wenying Shi, Zhize Chen
Summary: Polyethylene glycol-polydimethylsiloxane copolymer (PEG-PDMS) was incorporated into polylactic acid (PLA) via melt blending to improve its toughness and transparency, resulting in increased elongation at break and tensile strength, as well as enhanced crystallinity. Additionally, the energy storage modulus and complex viscosity of the blends were improved. However, the light transmittance slightly decreased.
JOURNAL OF APPLIED POLYMER SCIENCE
(2023)
Article
Engineering, Biomedical
Kosei Utatsu, Tetsuya Kogo, Toru Taharabaru, Risako Onodera, Keiichi Motoyama, Taishi Higashi
Summary: A new transformable mixing-type material, PEG-NH2-PRX, was developed for reversible PEGylation of protein drugs with high mobility of amino groups. Compared to the control material PEG-NH2-DEX, PEG-NH2-PRX efficiently formed complexes with protein drugs, improving stability of antibodies and prolonging hypoglycemic effects of insulin without loss of bioactivity, suggesting it as a promising material for reversible PEGylation of protein drugs.
MATERIALS TODAY BIO
(2021)
Article
Polymer Science
Alexandra-Diana Diaconu, Corina-Lenuta Logigan, Catalina Anisoara Peptu, Constanta Ibanescu, Valeria Harabagiu, Cristian Peptu
Summary: Polymer networks based on cyclodextrin and polyethylene glycol were prepared and characterized. The hydrophilic and encapsulation properties were confirmed, and the influence of crosslinking reaction feed was investigated. The thermal water swelling and hydrolytic degradation were studied, and the drug loading and release capacity were evaluated.
Article
Polymer Science
Fei Peng, Xingwen Yang, Yun Zhu, Guiyou Wang
Summary: The macroscopic properties of polymers can be greatly influenced by subtle structural changes in the building blocks, making it crucial to investigate the structure-property relationships in order to optimize the thermal, mechanical, and optoelectrical characteristics. This study focuses on polyurethane elastomers (PUEs), which contain both soft and hard segments, and explores the effects of structural symmetry in the soft segments on the structure, morphology, and mechanical properties of the PUEs. The results demonstrate the importance of structural regularity in achieving enhanced performance in PUE materials.
Article
Polymer Science
Chen Zhang, Zhanping Zhang, Yuhong Qi
Summary: Introducing polystyrene microspheres into hydrogels can significantly improve the compressive strength and swelling degree, while gradually reducing the surface energy of the hydrogels.
Article
Biochemistry & Molecular Biology
Ahlem Meziadi, Navid Zuberi, Hendrick W. de Haan, Marc A. Gauthier
Summary: This study reveals that the inefficiency of bioconjugation reactions, such as protein PEGylation, is caused by the excluded volume effect (EVE) between methoxy poly(ethylene glycol) (mPEG) and proteins. The researchers found that this EVE leads to the self-assembly of proteins and reactive mPEG into separate protein-rich and mPEG-rich domains. By adding unreactive low-molecular weight mPEG as a co-solvent, the association between the larger protein and reactive mPEG can be promoted, resulting in improved reaction efficiency.
Article
Polymer Science
Cristian Peptu, Alexandra-Diana Diaconu, Maricel Danu, Catalina A. Peptu, Mariana Cristea, Valeria Harabagiu
Summary: This study investigated the influence of hydroxyl group type on the polyaddition reactions of isocyanates and the structure/properties of resulting polyurethane hydrogels. By comparing native beta-cyclodextrin (CD) and its derivative esterified with oligolactide chains (CDLA), different networks were formed. The results show that the presence of primary hydroxyl groups leads to more compact networks with similar water uptake, while the predominance of secondary hydroxyl groups and the presence of oligolactide spacers allow for fine-tuning of the water swelling properties.
Article
Biochemistry & Molecular Biology
Marcell Arpad Kordovan, Csaba Hegedus, Katalin Czifrak, Csilla Lakatos, Ibolya Kalman-Szabo, Lajos Daroczi, Miklos Zsuga, Sandor Keki
Summary: This paper presents the synthesis, characterization, and properties of crosslinked poly(epsilon-caprolactone)-based polyurethanes for tissue replacement materials. The polyurethane prepolymers were prepared from poly(epsilon-caprolactone)diol, polyethylene glycol/polylactic acid diol, and 1,6-hexamethylene diisocyanate. The resulting polyurethanes were characterized using various techniques and their feasibility for dental tissue repair was investigated.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Polymer Science
Xiaolong Su, Shikui Jia, Le Cao, Demei Yu
Summary: A novel strategy to improve the toughness of polylactic acid is developed in this work by adjusting processing temperature during the melt-blending process, resulting in ternary blends with improved interfacial compatibility and fibrillated micro-morphology. The synergistic action of in-situ fibrillated TPU and stereocomplex (SC) crystals significantly enhances the toughness of the ternary blends without sacrificing its own tensile strength, while also improving their melt strength for processing applications.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Yu Ding, Haotian Ma, Xin Liu, Shengxue Qin, Jie Liu, Guanhang Qu, Yaozong Bai, Lifen Zhao
Summary: By synthesizing reactive isocyanate-modified graphene oxide (mGO) as an enhancer, the mechanical properties of PLA/PEG blends were successfully improved. The performance of the interface was enhanced by the formation of polyurethane (PU) between GO and the matrix. Moreover, the in situ formed PU also improved the relaxation time of molecule motion, leading to better shape-memory recovery rate and final recovery degree of the composites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Materials Science, Composites
Lixiang Yu, Xiaohong Qin, Guizhen Ke, Jiani Tang, Yu Wang
Summary: This work successfully fabricated a textile with phase change and electrothermal function using a novel method. The resulting composite fabric possesses good phase change reliability and exhibits great electrothermal repeatability, making it a promising material with various applications.
COMPOSITES COMMUNICATIONS
(2022)
