Article
Chemistry, Multidisciplinary
Navid Rabiee, Mojtaba Bagherzadeh, Amir Mohammad Ghadiri, Mahsa Kiani, Yousef Fatahi, Maryam Tavakolizadeh, Ali Pourjavadi, Maryam Jouyandeh, Mohammad Reza Saeb, Masoud Mozafari, Mohammadreza Shokouhimehr, Rajender S. Varma
Summary: The nanocomposite synthesized with a molecular engineering strategy demonstrates enhanced stability in the biological matrix, low cytotoxicity, controllable cellular internalization, and superior photocatalytic and gene delivery properties. The physical interaction between CRISPR/Cas9 and the nanomaterial is observed for the first time, leading to increased protein expression. Additionally, the nanocomposite exhibits strong antibacterial activity and potential for codelivery of therapeutic agents in clinical applications.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2021)
Article
Materials Science, Composites
Sinan Feng, Cong Liu, Hung-Jue Sue
Summary: This study presents an alternative strategy for the preparation of high-performance PEEK/MWCNT nanocomposites using an interfacial crystallization approach. By utilizing a polyetheretherketimine (PEEKt) to prepare PEEK nanocomposites, good dispersion of MWCNTs in the PEEK matrix is achieved without the need for surfactants or compatibilizers. The resulting nanocomposites exhibit improved properties and have potential applications in fields such as energy production, electrochemical devices, and coatings under harsh conditions.
COMPOSITES SCIENCE AND TECHNOLOGY
(2022)
Review
Engineering, Biomedical
Adam Shearer, Maziar Montazerian, Jessica J. Sly, Robert G. Hill, John C. Mauro
Summary: At least 25 bioactive glass medical devices have been approved for clinical use worldwide. These devices have diverse applications, including implants, fillers, agents for dentin hypersensitivity, wound dressing, and cancer therapeutics. Bioactive glasses have evolved in morphology and delivery systems, allowing for greater flexibility and control. This article critically discusses the approved products, regulatory standards, and the future development, applications, and challenges of bioactive glasses.
ACTA BIOMATERIALIA
(2023)
Article
Polymer Science
Kevin Rakotoaridina, Julien Delrieu, Paul Pages, Thierry Verge, Karim Nasr, Thibault Canceill
Summary: This study evaluates the fracture resistance of PEEK posts-and-cores compared to non-metallic CAD/CAM materials and fiber glass posts. The results show that glass fiber posts and Numerys GF® have higher fracture resistance than LuxaCam® PEEK and Enamic®. The study suggests that PEEK can be used for dental restoration in specific cases.
Article
Chemistry, Multidisciplinary
N. Alasvand, A. Behnamghader, P. B. Milan, M. Mozafari
Summary: This study successfully synthesized modified borate-based bioactive glasses with anticoagulant, antibacterial, and angiogenesis properties, showing great potential in blood-contact applications and vascular tissue engineering.
MATERIALS TODAY CHEMISTRY
(2023)
Article
Engineering, Biomedical
Nuha Al-Harbi, Mahmoud A. Hussein, Yas Al-Hadeethi, Raed I. Felimban, Hossam H. Tayeb, Nada M. H. Bedaiwi, Abeer M. Alosaimi, Elena Bekyarova, Mingguag Chen
Summary: The present study aimed to fabricate hybrid bioactive membrane for dental applications using the casting dissolution procedures. The fabricated nanocomposites showed good compatibility and had a semi crystalline structure. The nanocomposites exhibited good thermal behaviors and bioactivity. The prepared nanocomposites did not exhibit antibacterial activity against pathogenic bacterial strains. Additionally, the nanocomposites showed mild to non-cytotoxicity to Vero cells, making them promising candidates for dental applications.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2023)
Article
Chemistry, Analytical
Agata Baranowska, Marcin Kochanowicz, Aleksandra Wajda, Magdalena Lesniak, Jacek M. Zmojda, Piotr Miluski, Izabela Zglobicka, Krzysztof J. Kurzydlowski, Dominik Dorosz
Summary: The study found that doping Sm3+ into 13-93 bioactive glass can reduce the degradation rate of glass fibers and accelerate the formation of hydroxycarbonate-apatite layers. Optical analysis and SEM/EDS measurements can effectively monitor the degradation and surface morphology changes of fibers. This research demonstrates that monitoring changes in Sm3+ ion luminescence is a sensitive method for tracking the degradation of bioactive glass fibers.
Article
Materials Science, Multidisciplinary
Lakshmi M. Mukundan, Santanu Dhara, Santanu Chattopadhyay
Summary: This study synthesized multicomponent bioactive glass with spherical morphology and ordered mesoporous structure containing nanocrystals of apatite. These nanospheres, prepared through a sol-gel method, have a size range of 200-250 nm. The dispersed nanoapatite domains throughout the matrix affect structural properties and can potentially be used for drug delivery.
Article
Polymer Science
Adrian Korycki, Christian Garnier, Amandine Abadie, Valerie Nassiet, Charles Tarek Sultan, France Chabert
Summary: The study elaborated PEEK/PES blends with partial miscibility by melt mixing with phenolphthalein, which was confirmed by DSC and DMTA analysis. Phenolphthalein acted as a compatibilizer and plasticizer for the blends, resulting in a softened PEEK phase and improved interfacial adhesion with PES. Additionally, the storage modulus in the glassy region of the blends remained similar to pure PEEK due to the aromatic moieties in phenolphthalein.
Article
Materials Science, Multidisciplinary
Yannan Li, Juan Ge, Meng Luo, Wen Niu, Xiangwei Ling, Ke Xu, Cai Lin, Bo Lei, Xingxing Zhang
Summary: The study introduces a bioactive elastomeric self-healing antibacterial nanocomposite hydrogel scaffold for enhancing the skull defect reconstruction. The scaffold efficiently matches the skull defect morphology, enhances osteogenic differentiation, and regenerates bone tissues, showing significant potential in treating trauma-induced skull defects.
APPLIED MATERIALS TODAY
(2022)
Article
Engineering, Biomedical
Chenxi Xie, Meng Luo, Mi Chen, Min Wang, Xiaoyan Qu, Bo Lei
Summary: This study reports on the important role and mechanism of a novel polymer in skin wound repair. The polymer is found to modulate macrophage phenotype and promote angiogenesis, thus accelerating skin wound healing. Additionally, the polymer exhibits good biocompatibility with immune cells and tissue cells. These findings contribute to a better understanding and application of citrate-based biomaterials in tissue engineering.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Engineering, Environmental
Sebastian Wilk, David Medina-Cruz, Marcel Zambrzycki, Piotr K. Szewczyk, Marek Nocun, Elzbieta Menaszek, Thomas J. Webster, Aleksandra Benko
Summary: In this study, carbon nanofiber (CNF) - carbon nanotube (CNT) nanofibrous composites were fabricated by thermal treatment of electrospun polyacrylonitrile precursor. The presence of CNTs affected the structure and chemical composition of the CNF composites and improved their antibacterial performance. These materials exhibited excellent electrical conductivity, cytocompatibility, and antibacterial properties.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Materials Science, Multidisciplinary
Yanbo Wu, Li Tang, Qiang Zhang, Fansheng Kong, Yongguang Bi
Summary: Nanoscale bioactive glasses were successfully synthesized with remarkable mono-dispersity and uniform spherical morphology using a surfactant-free microemulsion strategy combined with ultrasound irradiation. The bioactive glass nanoparticles demonstrated excellent apatite-forming activity, making them a promising candidate for local sustained delivery in bone tissue engineering.
Article
Chemistry, Physical
Roberta M. Sabino, Julietta V. Rau, Angela De Bonis, Adriana De Stefanis, Mariangela Curcio, Roberto Teghil, Ketul C. Popat
Summary: Titanium and its alloys are commonly used biomaterials for orthopedic and dental applications, but up to 10% of medical devices may still fail. A novel surface modification method using manganese-containing bioactive glass has been shown to enhance osteogenic activity on titanium, reducing the risk of device failure.
APPLIED SURFACE SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Wen Niu, Mi Chen, Yi Guo, Min Wang, Meng Luo, Wei Cheng, Yidan Wang, Bo Lei
Summary: This study introduces a multifunctional branched bioactive Si-Ca-P-Mo glass-ceramic nanoparticle useful for post-surgical melanoma therapy, infection therapy, and skin regeneration. The mixed-valence molybdenum doped BBGN (BBGN-Mo) shows excellent photothermal, antibacterial, enzyme-like radical scavenging, and anti-inflammatory properties, as well as enhanced vascularization efficiencies.
Article
Materials Science, Multidisciplinary
Yanyan Zheng, Chengdong Xiong, Dujuan Zhang, Lifang Zhang
BULLETIN OF MATERIALS SCIENCE
(2018)
Article
Engineering, Chemical
Yanyan Zheng, Lvhua Liu, Ying Ma, Li Xiao, Ying Liu
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2018)
Article
Materials Science, Multidisciplinary
Yanyan Zheng, Lvhua Liu, Chengdong Xiong, Lifang Zhang
Article
Biophysics
Yanyan Zheng, Lvhua Liu, Li Xiao, Qianyu Zhang, Ying Liu
COLLOIDS AND SURFACES B-BIOINTERFACES
(2019)
Article
Engineering, Biomedical
Nan Hu, Lingxia Xie, Qing Liao, Ang Gao, Yanyan Zheng, Haobo Pan, Liping Tong, Dazhi Yang, Nong Gao, Marco J. Starink, Paul K. Chu, Huaiyu Wang
Summary: The study refined the grain size of beta-type Ti-45Nb alloy through high-pressure torsion processing, increasing tensile strength while maintaining a low elastic modulus. Grain boundary strengthening improved corrosion resistance by facilitating the formation of thicker and less defective passive films, leading to suppression of the inflammatory response.
ACTA BIOMATERIALIA
(2021)
Correction
Oncology
Li Xiao, Qiannan Hu, Yanshuang Peng, Kaiyue Zheng, Ting Zhang, Lianjie Yang, Zhi Wang, Wanrong Tang, Jie Yu, Qian Xiao, Dandan Zhang, Weifang Zhang, Chanjuan He, Dengxun Wu, Yanyan Zheng, Ying Liu
Article
Oncology
Li Xiao, Qiannan Hu, Yanshuang Peng, Kaiyue Zheng, Ting Zhang, Lianjie Yang, Zhi Wang, Wanrong Tang, Jie Yu, Qian Xiao, Dandan Zhang, Weifang Zhang, Chanjuan He, Dengxun Wu, Yanyan Zheng, Ying Liu
Summary: This study found that CAFs in oral squamous cell carcinoma exhibit greater mitochondrial activity and preferentially use oxidative phosphorylation for glucose metabolism. TRAP1 was identified as an important regulatory molecule in CAFs, promoting OSCC progression by regulating OXPHOS.
Article
Materials Science, Multidisciplinary
Lvhua Liu, Weifang Zhang, Lei Yuan, Ying Liu, Yanyan Zheng
Summary: The introduction of sulfonate groups onto PEEK surface enhances antibacterial, anti-inflammatory, and osteogenic activity, as well as adhesion, spreading, and proliferation of osteoblasts. Sulfonate-bearing PEEK shows potential clinical applications as orthopedic and dental implants.
Article
Engineering, Biomedical
Yanyan Zheng, Ang Gao, Jiaxiang Bai, Qing Liao, Yuzheng Wu, Wei Zhang, Min Guan, Liping Tong, Dechun Geng, Xin Zhao, Paul K. Chu, Huaiyu Wang
Summary: This article introduces a method to design and fabricate a programmable surface on PEEK to sequentially regulate osteoimmunomodulation and bone regeneration, improving the osseointegration of bone implants, especially under osteoporotic conditions.
BIOACTIVE MATERIALS
(2022)
Article
Materials Science, Multidisciplinary
Lvhua Liu, Jun Dong, Weifang Zhang, Chanjuan He, Ying Liu, Yanyan Zheng
Summary: Polyetheretherketone (PEEK) is a potential material for orthopedic implants due to its similar elastic modulus to human bone. However, its poor osteogenic activity limits its clinical application. In this study, PEEK surface was grafted with poly (sodium vinylsulfonate) to improve its osteogenic activity. The results showed that grafting with poly (sodium vinylsulfonate) enhanced MC3T3-E1 osteoblast compatibility and osteogenic activity of the PEEK surface, especially with a higher grafting amount.
Article
Materials Science, Multidisciplinary
Yanyan Zheng, Huang Zhou, Mengqi Li, Jingjing Fu, Jun Dong, Ying Liu, Lvhua Liu
Summary: This study successfully enhanced the osteogenic capability of PEEK by engineering its surface with a degradable hybrid coating. The coated PEEK showed improved biocompatibility and osteogenic performance, making it a promising material for orthopedic and dental applications.
Article
Chemistry, Physical
Huang Zhou, Yanyan Zheng, Xiu He, Jingjing Fu, Jun Liu
Summary: Waterweed-like nanostructured photoanodes (PAs) were proposed as a highly efficient design for photoelectrochemical water splitting. By depositing Cu dendrites on flexible meshes and coating them with a nano-g-C3N4 catalyst, an unprecedented photocurrent density of over 96 μA/cm-2 was achieved, which was 96 times higher than that of flat-type PAs. The superior performance of waterweed-like PAs was attributed to efficient light capture and a large surface area for catalyst loading.
ACS APPLIED ENERGY MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Weifang Zhang, Lvhua Liu, Huang Zhou, Chanjuan He, Xueli Yang, Jingjing Fu, Huaiyu Wang, Ying Liu, Yanyan Zheng
Summary: Polyetheretherketone (PEEK) is a promising alternative to biomedical metals for orthopedic and dental implantation due to its bone-like elastic modulus and good biocompatibility. However, PEEK elicits an inflammatory immune response after implantation, leading to inferior osseointegration. Surface bisphosphonation of PEEK can mitigate the immune response and promote angiogenesis and osteogenesis, improving osseointegration.
MATERIALS & DESIGN
(2023)
Correction
Chemistry, Multidisciplinary
Lvhua Liu, Yanyan Zheng, Qianyu Zhang, Lin Yu, Ziliang Hu, Ying Liu
Article
Chemistry, Multidisciplinary
Lvhua Liu, Yanyan Zheng, Qianyu Zhang, Lin Yu, Ziliang Hu, Ying Liu