Article
Chemistry, Analytical
Guopan Liu, Ming Ho Choi, Haiying Ma, Xuejiao Guo, Pui-Chi Lo, Jinyong Kim, Liang Zhang
Summary: Surface biotinylation is widely used to analyze the cellular proteome associated with the plasma membrane. However, it is prone to interference from cytoplasmic biotin-associated proteins. This study established a new workflow (BCAP) that utilizes a bioorthogonal conjugation reaction to minimize interference and efficiently isolate surface proteins.
ANALYTICAL CHEMISTRY
(2022)
Article
Multidisciplinary Sciences
Shuna Jiang, Liying Pan, Qingfeng Zhou, Wenjie Xu, Fuge He, Lei Zhang, Hang Gao
Summary: The apoplastic proteome is found to be involved in systemic acquired resistance (SAR), providing valuable insights into the molecular mechanisms underlying SAR.
Article
Plant Sciences
Jingli Yan, Qinqin Chen, Xing Cui, Peiyu Zhao, Shidong Gao, Bo Yang, Jian-Xiang Liu, Tiantian Tong, Michael K. Deyholos, Yuan-Qing Jiang
Summary: The research reveals that BnaNAC60 is a membrane-tethered NAC transcription factor associated with the endoplasmic reticulum membrane, whose expression is induced during leaf senescence. Translocation of BnaNAC60 to the nucleus is triggered by ER and oxidative stress treatments, leading to modulation of cell death, ROS accumulation, and leaf senescence. Additionally, BnaNAC60 can activate the promoter activities of various downstream target genes, suggesting its role in regulating plant stress responses and developmental processes.
Article
Biochemistry & Molecular Biology
Juan A. Montero, Carlos Ignacio Lorda-Diez, Juan M. Hurle
Summary: This paper proposes a new perspective on the regulation of programmed cell death (PCD) in developing systems based on epigenetics. It challenges the traditional view that PCD is solely controlled by specific gene-encoded signals, arguing that the signals and local tissue interactions responsible for embryonic tissue growth and differentiation play a significant role in PCD. The study suggests that cells retain an epigenetic profile sensitive to DNA damage, resulting in their subsequent elimination.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biology
Erhui Xiong, Guojun Dong, Fei Chen, Chen Zhang, Shan Li, Yanli Zhang, Jahidul Islam Shohag, Xiaoe Yang, Yihua Zhou, Qian Qian, Limin Wu, Yanchun Yu
Summary: The study identified a novel rice mutant with abnormal tetrahydrofolate cycle, leading to H(2)O(2) accumulation and early leaf senescence. The deficiency of HPA1, encoding a tetrahydrofolate deformylase, resulted in altered folate status and redox homeostasis, subsequently triggering leaf senescence. The accumulation of H(2)O(2) in Hpa1 may be mediated by changes in mitochondrial oxidative phosphorylation complexes and can be compensated by exogenous antioxidant GSH.
SCIENCE CHINA-LIFE SCIENCES
(2021)
Article
Horticulture
Fan Guo, Airu Han, Haiyan Gao, Jingyi Liang, Ke Zhao, Shifeng Cao, Hongfei Wang, Yingying Wei, Xingfeng Shao, Feng Xu
Summary: Mannose treatment effectively inhibited chlorophyll degradation and programmed cell death in broccoli florets stored at 20 degrees Celsius, delaying senescence in broccoli florets.
SCIENTIA HORTICULTURAE
(2022)
Review
Plant Sciences
Yukun Wang, Hong Ye, Jianfang Bai, Fei Ren
Summary: Developmentally programmed cell death plays a vital role in regulating floral organ growth and development, involving factors such as tapetal degeneration, pollen tube rupture, receptive synergid cell death, nucellar degradation, and antipodal cell degradation. Understanding the complex molecular networks involved in floral dPCD processes provides insights into flower-specific dPCD process.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Qianqian Jiang, He Wang, Zichun Qiao, Yutong Hou, Zhigang Sui, Baofeng Zhao, Zhen Liang, Bo Jiang, Yukui Zhang, Lihua Zhang
Summary: Systematic analysis of the membrane proteome of living cells is crucial for understanding cellular processes and relationships between membrane-bound organelles. However, enriching and analyzing membrane proteins in their native state remains challenging. To address this, researchers developed a cell surface engineering method that uses biomembrane fusion to map the membrane proteome. This approach bypasses traditional fractionation methods and enables specific and comprehensive analysis of membrane proteins.
Review
Plant Sciences
Shazia Parveen, Foziya Altaf, Sumira Farooq, Mohammad Lateef Lone, Aehsan ul Haq, Inayatullah Tahir
Summary: Flower senescence is a complex process involving cytological, physiological, and molecular changes, similar to programmed cell death. Ethylene plays a crucial role in ethylene-dependent petal senescence, triggering various changes such as wilting, oxidative stress, protein and nucleic acid degradation, and autophagy. Despite advances in understanding the mechanism and regulation of petal senescence, there are still knowledge gaps that require critical evaluation of the available literature. A deeper understanding of ethylene-dependent senescence can lead to improved regulation of senescence timing and site, resulting in optimized crop yields, enhanced product quality, and extended longevity.
JOURNAL OF EXPERIMENTAL BOTANY
(2023)
Article
Multidisciplinary Sciences
Matthias Van Durme, Yadira Olvera- Carrillo, Marie L. Pfeiffer, Nicolas M. Doll, Freya De Winter, Zongcheng Lin, Moritz K. Nowack
Summary: Flowers have a specific fertile period in which pollination and fertilization must occur for seed and fruit development to begin. Unpollinated flowers can remain receptive for a few hours or several weeks before becoming infertile. Floral longevity, specifically the lifespan of the ovule, is influenced by natural selection and plant breeding. The aging process of unfertilized ovules in Arabidopsis thaliana exhibits characteristics of programmed cell death, with significant transcriptomic changes. Up-regulated transcription factors, such as NAP/ANAC029, SHYG/ANAC047, and ORE1/ANAC092, regulate ovule senescence and can extend fertility in Arabidopsis ovules.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Review
Chemistry, Multidisciplinary
Lu Wang, Yiqi Wu, Renqi Yao, Yun Li, Yurou Wei, Yuan Cao, Zicheng Zhang, Mengyao Wu, Hanyu Zhu, Yongming Yao, Hongjun Kang
Summary: Mesenchymal stem cells (MSCs) have been extensively studied for their immunomodulatory properties in inflammatory diseases. Recently, MSC-derived extracellular vesicles (MSC-EVs) have gained attention as a major pathway for intercellular communication. This review summarizes the potential influences of MSC-EVs on different types of programmed cell death and diseases, and discusses the therapeutic effects, current research progress, and challenges of clinical applications of MSC-EVs. Understanding the regulation of inflammation-associated programmed cell death by MSC-EVs is important for identifying molecular mechanisms and modulatory targets.
Review
Microbiology
Thomas J. Williams, Luis E. Gonzales-Huerta, Darius Armstrong-James
Summary: Fungal infections are a significant health concern with high mortality rates despite available antifungal treatments, prompting further research into fungal pathogenic mechanisms. Researchers discuss the induction of programmed cell death by microbes and how fungi manipulate these pathways.
Article
Geosciences, Multidisciplinary
Tessa Camenzind, Kyle Mason-Jones, India Mansour, Matthias C. Rillig, Johannes Lehmann
Summary: Microbial death pathways in soil affect the composition and fate of microbial necromass, which is important for soil organic carbon storage. The composition of microbial necromass is different from microbial biomass, as it undergoes distinct chemical transformations. Different environmental conditions and microbial death pathways influence the changes in necromass composition.
Review
Cell Biology
Weida Ren, Wanyu Zhao, Lingbo Cao, Junqi Huang
Summary: Research on programmed cell death (PCD) reveals that cells undergo orderly cell death through evolutionary regulatory mechanisms, with actin playing a crucial role in cellular processes. Scientists aim to further understand the intricate relationship between PCD and the actin cytoskeleton.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Otto Teixeira Fraga, Bruno Paes de Melo, Iana Pedro Silva Quadros, Pedro Augusto Braga Reis, Elizabeth Pacheco Batista Fontes
Summary: Leaf senescence is a genetically regulated developmental process that can be triggered by various signals, including transcription factors and NAC genes. By studying soybean GmNAC-SAGs and their functional correlation with Arabidopsis NAC-SAGs, some regulatory mechanisms and gene networks have been identified.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
