Melatonin sensitizes Caki renal cancer cells to kahweol-induced apoptosis through CHOP-mediated up-regulation of PUMA

CHOP and AP-1 cooperatively mediate PUMA expression during lipoapoptosis

(2010) Sophie C. Cazanave et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The coffee diterpene kahweol sensitizes TRAIL-induced apoptosis in renal carcinoma Caki cells through down-regulation of Bcl-2 and c-FLIP

(2010) Hee Jung Um et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Implication of TAp73 in the p53-independent pathway of Puma induction and Puma-dependent apoptosis in primary cortical neurons

(2010) Michael Fricker et al.   JOURNAL OF NEUROCHEMISTRY

Protective effect of melatonin on oxaliplatin-induced apoptosis through sustained Mcl-1 expression and anti-oxidant action in renal carcinoma Caki cells

(2010) Hee Jung Um et al.   JOURNAL OF PINEAL RESEARCH

Melatonin induces pro-apoptotic signaling pathway in human pancreatic carcinoma cells (PANC-1)

(2010) Anna Leja-Szpak et al.   JOURNAL OF PINEAL RESEARCH

The coffee diterpene kahweol induces apoptosis in human leukemia U937 cells through down-regulation of Akt phosphorylation and activation of JNK

(2009) Jung Hwa Oh et al.   APOPTOSIS

Melatonin present in beer contributes to increase the levels of melatonin and antioxidant capacity of the human serum

(2009) Maria D. Maldonado et al.   CLINICAL NUTRITION

Melatonin induces mitochondrial-mediated apoptosis in human myeloid HL-60 cells

(2009) Ignacio Bejarano et al.   JOURNAL OF PINEAL RESEARCH

Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines

(2009) Rüdiger Hardeland et al.   JOURNAL OF PINEAL RESEARCH

Reactions of the melatonin metaboliteN1-acetyl-5-methoxykynuramine with carbamoyl phosphate and related compounds

(2009) Jana T. Kuesel et al.   JOURNAL OF PINEAL RESEARCH

Sirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer

(2009) Brittney Jung-Hynes et al.   JOURNAL OF PINEAL RESEARCH

PUMA, a potent killer with or without p53

(2009) J Yu et al.   ONCOGENE

Kahweol blocks STAT3 phosphorylation and induces apoptosis in human lung adenocarcinoma A549 cells

(2009) Hyung Gyun Kim et al.   TOXICOLOGY LETTERS

Potential role of tryptophan derivatives in stress responses characterized by the generation of reactive oxygen and nitrogen species

(2008) Fabienne Peyrot et al.   JOURNAL OF PINEAL RESEARCH

The melatonin metaboliteN1-acetyl-5-methoxykynuramine is a potent singlet oxygen scavenger

(2008) Meike Schaefer et al.   JOURNAL OF PINEAL RESEARCH

The multifaceted mechanisms for coffee’s anti-tumorigenic effect on liver

(2008) Kai-Shan Tao et al.   MEDICAL HYPOTHESES