Article
Biology
Allison E. Hamilos, Giulia Spedicato, Ye Hong, Fangmiao Sun, Yulong Li, John A. Assad
Summary: The study revealed that dopamine signals play a crucial role in the timing of reward-related movements in animals, with the signals gradually increasing over time to predict movement/reward timing. The dynamics of dopamine signals can modulate the probability of movement initiation, providing important insights into the decision of when to move.
Article
Neurosciences
Adam J. Culbreth, Zuzana Kasanova, Thomas J. Ross, Betty J. Salmeron, James M. Gold, Elliot A. Stein, James A. Waltz
Summary: The study found that brain responses to different forms of salience were detected, and there were no significant differences in salient event activation between SZ patients and controls in several regions, but there was a significant correlation between the magnitudes of salience contrasts and positive symptoms in SZ patients.
Article
Multidisciplinary Sciences
Emil Warnberg, Arvind Kumar
Summary: This article discusses the role of midbrain dopaminergic neurons in the basal ganglia and how to explain how dopamine supports learning of continuous outputs instead of discrete action values. The authors propose a model and demonstrate its validity through a learning rule.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Biochemistry & Molecular Biology
Helena J. Barr, Erin M. Wall, Sarah C. Woolley
Summary: Vocal communication signals can shape the incentive salience of communication signals through dopamine within auditory cortical circuits, not norepinephrine. Dopamine enhances preferences for less-preferred songs, and this plasticity can persist for at least 1 week.
Article
Multidisciplinary Sciences
Bradley M. Colquitt, Devin P. Merullo, Genevieve Konopka, Todd F. Roberts, Michael S. Brainard
Summary: Research has shown that the vocal circuits in songbirds and the neocortex in mammals have distinct developmental origins, yet the neurons exhibit transcriptional similarities.
Article
Anatomy & Morphology
Carolin Scholl, Javier Baladron, Julien Vitay, Fred H. Hamker
Summary: Research reveals that Tourette patients have an increased propensity to habitual behaviors. A neuro-computational model suggests that enhanced habit formation in Tourette patients may be linked to faster plasticity in shortcut connections or stronger feedback from the shortcut to the basal ganglia. This study provides a theoretical basis for further understanding the pathophysiology of Tourette syndrome and potential treatment strategies.
BRAIN STRUCTURE & FUNCTION
(2022)
Article
Cell Biology
Kristen Delevich, Benjamin Hoshal, Lexi Z. Zhou, Yuting Zhang, Satya Vedula, Wan Chen Lin, Juliana Chase, Anne G. E. Collins, Linda Wilbrecht
Summary: This study investigates the role of direct and indirect pathway spiny projection neurons (dSPNs and iSPNs) in choice rejection during learning. The results show that activation of iSPNs disrupts rejection of nonrewarded choices. These findings are important for designing interventions to enhance choice rejection in addiction or other conditions.
Article
Biochemistry & Molecular Biology
Arnaud L. Lalive, Mauro Congiu, Christopher Lewis, Dominik Groos, Joseph A. Clerke, Anna Tchenio, Yuan Ge, Fritjof Helmchen, Manuel Mameli
Summary: Through experiments with mice, it was found that the activity of lateral habenula neurons decreases with the decrease of reward-related stimuli, and this phenomenon can guide reward-driven behavior through synaptic inhibition.
Article
Biology
Csongor Vagasi, Attila Fulop, Gergely Osvath, Peter L. Pap, Janka Penzes, Zoltan Benko, Adam Z. Lendvai, Zoltan Barta
Summary: The diversity of personality within a social group can affect the physiological state of group members, with increasing diversity leading to improved body condition, physiological stress, and oxidative damage. Individuals benefit from associating with a diverse set of behavioral types within a social environment.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2021)
Article
Biology
Alana Jaskir, Michael J. Frank
Summary: The basal ganglia plays a role in reinforcement learning and decision making, utilizing complex circuitry and dynamic dopamine modulation to achieve this. The OpAL* model highlights the normative advantages of this circuitry, showing how opponent pathways and dopamine modulation enhance learning and decision-making.
Article
Anatomy & Morphology
Gianpaolo Antonio Basile, Marina Quartu, Salvatore Bertino, Maria Pina Serra, Marcello Trucas, Marianna Boi, Roberto Demontis, Alessia Bramanti, Giuseppe Pio Anastasi, Demetrio Milardi, Rosella Ciurleo, Alberto Cacciola
Summary: This study successfully reconstructed the fiber bundles of the human subthalamic area and created a large-scale normative population atlas using an optimized tractography protocol. This atlas is of great significance in both clinical anatomy and functional neurosurgery, as it improves our understanding of the complex morphology of this important brain region.
BRAIN STRUCTURE & FUNCTION
(2022)
Article
Physics, Fluids & Plasmas
Goncalo Paulo, Mykola Tasinkevych
Summary: Synchronized behavior in a system of coupled dynamic objects is a fascinating example of cooperative phenomena, which can be suppressed by introducing contrarian oscillators. The mobility of oscillators and the presence of heterogeneous interactions both impact synchronization dynamics.
Review
Behavioral Sciences
Jonathan J. Cannon, Aniruddh D. Patel
Summary: This study proposes that beat anticipation relies on action-like processes in the brain, orchestrated by neural time-keeping activity in the supplementary motor area (SMA) and the dorsal striatum. By synthesizing recent advances in cognitive science and motor neuroscience, the framework provides testable predictions for future research.
TRENDS IN COGNITIVE SCIENCES
(2021)
Article
Neurosciences
Vinith Johnson, Robert Wilt, Roee Gilron, Juan Anso, Randy Perrone, Martijn Beudel, Dan Pina-Fuentes, Jeremy Saal, Jill L. Ostrem, Ian Bledsoe, Philip Starr, Simon Little
Summary: The study utilized a novel, sensing-enabled deep brain stimulator device implanted in a patient with cervical dystonia to record neural data and conduct a proof-of-principle trial. It found that low-frequency oscillations are related to dystonia and demonstrated the potential for a novel adaptive stimulation strategy.
EXPERIMENTAL NEUROLOGY
(2021)
Article
Neurosciences
Adam Gordon-Fennell, Garret D. Stuber
Summary: Studies have revealed generalizable findings across molecularly defined cell types in areas of the basal forebrain and anterior hypothalamus. Optogenetic stimulation of GABAergic neurons in these brain regions drives reward, while optogenetic stimulation of glutamatergic neurons in these regions drives aversion.
Editorial Material
Mathematical & Computational Biology
Meropi Topalidou, Arthur Leblois, Thomas Boraud, Nicolas P. Rougier
FRONTIERS IN COMPUTATIONAL NEUROSCIENCE
(2015)
Article
Neurosciences
Takafumi Arakaki, Severine Mahon, Stephane Charpier, Arthur Leblois, David Hansel
JOURNAL OF NEUROSCIENCE
(2016)
Article
Neurosciences
Jorge Alliende, Nicolas Giret, Ludivine Pidoux, Catherine del Negro, Arthur Leblois
Article
Multidisciplinary Sciences
Ran Darshan, William E. Wood, Susan Peters, Arthur Leblois, David Hansel
NATURE COMMUNICATIONS
(2017)
Article
Neurosciences
M. Guthrie, A. Leblois, A. Garenne, T. Boraud
JOURNAL OF NEUROPHYSIOLOGY
(2013)
Review
Neurosciences
Thomas Boraud, Arthur Leblois, Nicolas P. Rougier
PROGRESS IN NEUROBIOLOGY
(2018)
Article
Biochemical Research Methods
Ran Darshan, Arthur Leblois, David Hansel
PLOS COMPUTATIONAL BIOLOGY
(2014)
Article
Biology
Ludivine Pidoux, Pascale Le Blanc, Carole Levenes, Arthur Leblois
Article
Pharmacology & Pharmacy
Nicolas Mallet, Arthur Leblois, Nicolas Maurice, Corinne Beurrier
FRONTIERS IN PHARMACOLOGY
(2019)
Correction
Multidisciplinary Sciences
Brice de la Crompe, Asier Aristieta, Arthur Leblois, Salma Elsherbiny, Thomas Boraud, Nicolas P. Mallet
NATURE COMMUNICATIONS
(2020)
Article
Multidisciplinary Sciences
Brice de la Crompe, Asier Aristieta, Arthur Leblois, Salma Elsherbiny, Thomas Boraud, Nicolas P. Mallet
NATURE COMMUNICATIONS
(2020)
Review
Behavioral Sciences
Remya Sankar, Nicolas P. Rougier, Arthur Leblois
Summary: The plasticity of nervous systems plays a vital role in enabling animals to adapt to a changing environment. This review explores the significance of structural plasticity in brain networks and its contributions to computational models, using the example of vocal learning circuitry in zebra finches. The review discusses current evidence for structural plasticity across species, categorizes them based on spatial and developmental factors, and highlights the unanswered questions raised by modeling studies.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Proceedings Paper
Computer Science, Artificial Intelligence
Silvia Pagliarini, Xavier Hinaut, Arthur Leblois
2018 JOINT IEEE 8TH INTERNATIONAL CONFERENCE ON DEVELOPMENT AND LEARNING AND EPIGENETIC ROBOTICS (ICDL-EPIROB)
(2018)
Proceedings Paper
Computer Science, Artificial Intelligence
Cristobal J. Nettle, Maria-Jose Escobar, Arthur Leblois
2016 JOINT IEEE INTERNATIONAL CONFERENCE ON DEVELOPMENT AND LEARNING AND EPIGENETIC ROBOTICS (ICDL-EPIROB)
(2016)