The role of ubiquitin-mediated pathways in regulating synaptic development, axonal degeneration and regeneration: insights from fly and worm

Ubiquitination and selective autophagy

(2012) S Shaid et al.   CELL DEATH AND DIFFERENTIATION

RAE-1, a Novel PHR Binding Protein, Is Required for Axon Termination and Synapse Formation in Caenorhabditis elegans

(2012) B. Grill et al.   JOURNAL OF NEUROSCIENCE

A Conditioning Lesion Protects Axons from Degeneration via the Wallenda/DLK MAP Kinase Signaling Cascade

(2012) X. Xiong et al.   JOURNAL OF NEUROSCIENCE

Dual Leucine Zipper Kinase Is Required for Retrograde Injury Signaling and Axonal Regeneration

(2012) Jung Eun Shin et al.   NEURON

The Highwire Ubiquitin Ligase Promotes Axonal Degeneration by Tuning Levels of Nmnat Protein

(2012) Xin Xiong et al.   PLOS BIOLOGY

DLK induces developmental neuronal degeneration via selective regulation of proapoptotic JNK activity

(2011) Arundhati Sengupta Ghosh et al.   JOURNAL OF CELL BIOLOGY

Cullin-5 and cullin-2 play a role in the development of neuromuscular junction and the female germ line of Drosophila

(2011) CHAMPAKALI AYYUB   JOURNAL OF GENETICS

Highwire Regulates Guidance of Sister Axons in the Drosophila Mushroom Body

(2011) J. E. Shin et al.   JOURNAL OF NEUROSCIENCE

Drosophila Rae1 controls the abundance of the ubiquitin ligase Highwire in post-mitotic neurons

(2011) Xiaolin Tian et al.   NATURE NEUROSCIENCE

The role of ubiquitylation in nerve cell development

(2011) Hiroshi Kawabe et al.   NATURE REVIEWS NEUROSCIENCE

A Splice Isoform of DNedd4, DNedd4-Long, Negatively Regulates Neuromuscular Synaptogenesis and Viability in Drosophila

(2011) Yunan Zhong et al.   PLoS One

Ubiquitination in Postsynaptic Function and Plasticity

(2010) Angela M. Mabb et al.   Annual Review of Cell and Developmental Biology

Wallerian Degeneration, WldS, and Nmnat

(2010) Michael P. Coleman et al.   Annual Review of Neuroscience

A Ubiquitin E2 Variant Protein Acts in Axon Termination and Synaptogenesis in Caenorhabditis elegans

(2010) Gloriana Trujillo et al.   GENETICS

Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury

(2010) Xin Xiong et al.   JOURNAL OF CELL BIOLOGY

Calcium and Cyclic AMP Promote Axonal Regeneration in Caenorhabditis elegans and Require DLK-1 Kinase

(2010) A. Ghosh-Roy et al.   JOURNAL OF NEUROSCIENCE

A Novel Strategy to Isolate Ubiquitin Conjugates Reveals Wide Role for Ubiquitination during Neural Development

(2010) Maribel Franco et al.   MOLECULAR & CELLULAR PROTEOMICS

WldS, Nmnats and axon degeneration-progress in the past two decades

(2010) Yan Feng et al.   Protein & Cell

Impaired regenerative response of primary sensory neurons in ZPK/DLK gene-trap mice

(2009) Aki Itoh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The role of the ubiquitin proteasome system in synapse remodeling and neurodegenerative diseases

(2009) Mei Ding et al.   BIOESSAYS

The DLK-1 Kinase Promotes mRNA Stability and Local Translation in C. elegans Synapses and Axon Regeneration

(2009) Dong Yan et al.   CELL

mec-15 Encodes an F-Box Protein Required for Touch Receptor Neuron Mechanosensation, Synapse Formation and Development

(2009) A. Bounoutas et al.   GENETICS

Autophagy promotes synapse development inDrosophila

(2009) Wei Shen et al.   JOURNAL OF CELL BIOLOGY

PHR Regulates Growth Cone Pausing at Intermediate Targets through Microtubule Disassembly

(2009) M. Hendricks et al.   JOURNAL OF NEUROSCIENCE

Fbxo45 Forms a Novel Ubiquitin Ligase Complex and Is Required for Neuronal Development

(2009) T. Saiga et al.   MOLECULAR AND CELLULAR BIOLOGY

Phr1 regulates retinogeniculate targeting independent of activity and ephrin-A signalling

(2009) Susan M. Culican et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

A dual leucine kinase–dependent axon self-destruction program promotes Wallerian degeneration

(2009) Bradley R Miller et al.   NATURE NEUROSCIENCE

The Ubiquitin Ligase RPM-1 and the p38 MAPK PMK-3 Regulate AMPA Receptor Trafficking

(2009) Eun Chan Park et al.   PLoS One

Axon Regeneration Requires a Conserved MAP Kinase Pathway

(2009) M. Hammarlund et al.   SCIENCE

Roles of ubiquitination at the synapse

(2008) Kevin F. Haas et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Cellular and molecular determinants targeting theCaenorhabditis elegansPHR protein RPM-1 to perisynaptic regions

(2008) Benjamin Abrams et al.   DEVELOPMENTAL DYNAMICS

Think locally: control of ubiquitin-dependent protein degradation in neurons

(2008) Alexandra Segref et al.   EMBO REPORTS

A Mechanism Distinct from Highwire for the Drosophila Ubiquitin Conjugase Bendless in Synaptic Growth and Maturation

(2008) S. B. Uthaman et al.   JOURNAL OF NEUROSCIENCE

NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration

(2008) R. Grace Zhai et al.   NATURE

TheDrosophilaEpsin 1 is Required for Ubiquitin-Dependent Synaptic Growth and Function but Not for Synaptic Vesicle Recycling

(2008) Hong Bao et al.   TRAFFIC