CrossTalk proposal: The intermittent hypoxia attending severe obstructive sleep apnoea does lead to alterations in brain structure and function

Brain Activation Changes Before and After PAP Treatment in Obstructive Sleep Apnea

(2017) Vincenza Castronovo et al.   SLEEP

The Association between Obstructive Sleep Apnea and Neurocognitive Performance—The Apnea Positive Pressure Long-term Efficacy Study (APPLES)

(2017) Stuart F. Quan et al.   SLEEP

Human apolipoprotein E4 targeted replacement in mice reveals increased susceptibility to sleep disruption and intermittent hypoxia

(2012) Navita Kaushal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Disrupted sleep without sleep curtailment induces sleepiness and cognitive dysfunction via the tumor necrosis factor-α pathway

(2012) Vijay Ramesh et al.   Journal of Neuroinflammation

Cognition in Obstructive Sleep Apnea-Hypopnea Syndrome (OSAS): Current Clinical Knowledge and the Impact of Treatment

(2012) Stephanie A. Kielb et al.   NEUROMOLECULAR MEDICINE

High altitude exposure impairs sleep patterns, mood, and cognitive functions

(2012) Valdir Aquino Lemos et al.   PSYCHOPHYSIOLOGY

Sleep Fragmentation Induces Cognitive Deficits Via Nicotinamide Adenine Dinucleotide Phosphate Oxidase–dependent Pathways in Mouse

(2011) Deepti Nair et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cognitive Function in Prepubertal Children with Obstructive Sleep Apnea: A Modifying Role for NADPH Oxidase p22 Subunit Gene Polymorphisms?

(2011) David Gozal et al.   ANTIOXIDANTS & REDOX SIGNALING

Neurophysiological evidence for cognitive and brain functional adaptation in adolescents living at high altitude

(2011) Cassandra Richardson et al.   CLINICAL NEUROPHYSIOLOGY

Exogenous growth hormone attenuates cognitive deficits induced by intermittent hypoxia in rats

(2011) R.C. Li et al.   NEUROSCIENCE

Intermittent Hypoxia-Induced Cognitive Deficits Are Mediated by NADPH Oxidase Activity in a Murine Model of Sleep Apnea

(2011) Deepti Nair et al.   PLoS One

The Childhood Adenotonsillectomy Trial (CHAT): Rationale, Design, and Challenges of a Randomized Controlled Trial Evaluating a Standard Surgical Procedure in a Pediatric Population

(2011) Susan Redline et al.   SLEEP

Obstructive Sleep Apnea and Age

(2010) Liat Ayalon et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Obstructive Sleep Apnea: Brain Structural Changes and Neurocognitive Function before and after Treatment

(2010) Nicola Canessa et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Reactive oxygen species and the brain in sleep apnea

(2010) Yang Wang et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

A combined neuropsychological and brain imaging study of obstructive sleep apnea

(2009) KHALID YAOUHI et al.   JOURNAL OF SLEEP RESEARCH

Cognitive Effects of Treating Obstructive Sleep Apnea in Alzheimer's Disease: A Randomized Controlled Study

(2008) Sonia Ancoli-Israel et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY