Eccentric contractions increase the phosphorylation of tuberous sclerosis complex-2 (TSC2) and alter the targeting of TSC2 and the mechanistic target of rapamycin to the lysosome

Phosphatidic acid mediates the targeting of tBid to induce lysosomal membrane permeabilization and apoptosis

(2012) Kai Zhao et al.   JOURNAL OF LIPID RESEARCH

TBC1D7 Is a Third Subunit of the TSC1-TSC2 Complex Upstream of mTORC1

(2012) Christian C. Dibble et al.   MOLECULAR CELL

Mechanical Stimulation Induces mTOR Signaling via an ERK-Independent Mechanism: Implications for a Direct Activation of mTOR by Phosphatidic Acid

(2012) Jae Sung You et al.   PLoS One

The tuberous sclerosis complex: balancing proliferation and survival

(2011) Romana Tomasoni et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Class III PI-3-kinase activates phospholipase D in an amino acid–sensing mTORC1 pathway

(2011) Mee-Sup Yoon et al.   JOURNAL OF CELL BIOLOGY

The role of skeletal muscle mTOR in the regulation of mechanical load-induced growth

(2011) Craig A. Goodman et al.   JOURNAL OF PHYSIOLOGY-LONDON

Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids

(2010) Yasemin Sancak et al.   CELL

Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1/TSC2 in C2C12 myotubes

(2010) Mitsunori Miyazaki et al.   FEBS Journal

A Phosphatidylinositol 3-Kinase/Protein Kinase B-independent Activation of Mammalian Target of Rapamycin Signaling Is Sufficient to Induce Skeletal Muscle Hypertrophy

(2010) Craig A. Goodman et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

(2010) Shomit Sengupta et al.   MOLECULAR CELL

Reporting ethical matters inThe Journal of Physiology: standards and advice

(2009) Gordon B. Drummond   JOURNAL OF PHYSIOLOGY-LONDON

The role of phosphoinositide 3-kinase and phosphatidic acid in the regulation of mammalian target of rapamycin following eccentric contractions

(2009) T. K. O’Neil et al.   JOURNAL OF PHYSIOLOGY-LONDON

The nuts and bolts of AGC protein kinases

(2009) Laura R. Pearce et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The TSC1–TSC2 complex: a molecular switchboard controlling cell growth

(2008) Jingxiang Huang et al.   BIOCHEMICAL JOURNAL