Ion channels in genetic and acquired forms of epilepsy

Exome Sequencing Followed by Large-Scale Genotyping Fails to Identify Single Rare Variants of Large Effect in Idiopathic Generalized Epilepsy

(2012) Erin L. Heinzen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

De Novo Pathogenic SCN8A Mutation Identified by Whole-Genome Sequencing of a Family Quartet Affected by Infantile Epileptic Encephalopathy and SUDEP

(2012) Krishna R. Veeramah et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Autoimmune Epilepsy

(2012) Amy M. L. Quek   ARCHIVES OF NEUROLOGY

Inhibitory Interneuron Deficit Links Altered Network Activity and Cognitive Dysfunction in Alzheimer Model

(2012) Laure Verret et al.   CELL

Impaired Dendritic Expression and Plasticity of h-Channels in the fmr1−/y Mouse Model of Fragile X Syndrome

(2012) Darrin H. Brager et al.   Cell Reports

Neuron-restrictive silencer factor-mediated hyperpolarization-activated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsy

(2011) Shawn McClelland et al.   ANNALS OF NEUROLOGY

Exome Sequencing of Ion Channel Genes Reveals Complex Profiles Confounding Personal Risk Assessment in Epilepsy

(2011) Tara Klassen et al.   CELL

Genetic contribution to common epilepsies

(2011) Sanjay M Sisodiya et al.   CURRENT OPINION IN NEUROLOGY

Potentially pathogenic autoantibodies associated with epilepsy and encephalitis in children and adults

(2011) Angela Vincent et al.   EPILEPSIA

A perfect storm: Converging paths of epilepsy and Alzheimer’s dementia intersect in the hippocampal formation

(2011) Jeffrey Noebels   EPILEPSIA

Rapid Loss of Dendritic HCN Channel Expression in Hippocampal Pyramidal Neurons following Status Epilepticus

(2011) S. Jung et al.   JOURNAL OF NEUROSCIENCE

Autoantibodies associated with diseases of the CNS: new developments and future challenges

(2011) Angela Vincent et al.   LANCET NEUROLOGY

Presynaptic HCN1 channels regulate CaV3.2 activity and neurotransmission at select cortical synapses

(2011) Zhuo Huang et al.   NATURE NEUROSCIENCE

Dissecting functional connectivity of neuronal microcircuits: experimental and theoretical insights

(2011) Sarah Feldt et al.   TRENDS IN NEUROSCIENCES

Faciobrachial dystonic seizures precede Lgi1 antibody limbic encephalitis

(2010) Sarosh R. Irani et al.   ANNALS OF NEUROLOGY

HCN2 channels in local inhibitory interneurons constrain LTP in the hippocampal direct perforant path

(2010) Lucas Matt et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Increased seizure severity and seizure-related death in mice lacking HCN1 channels

(2010) Bina Santoro et al.   EPILEPSIA

Human limbic encephalitis serum enhances hippocampal mossy fiber-CA3 pyramidal cell synaptic transmission

(2010) Tatjana Lalic et al.   EPILEPSIA

Kv1.1 Potassium Channel Deficiency Reveals Brain-Driven Cardiac Dysfunction as a Candidate Mechanism for Sudden Unexplained Death in Epilepsy

(2010) E. Glasscock et al.   JOURNAL OF NEUROSCIENCE

Cellular and Synaptic Mechanisms of Anti-NMDA Receptor Encephalitis

(2010) E. G. Hughes et al.   JOURNAL OF NEUROSCIENCE

Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus

(2010) Nicole A. Hawkins et al.   NEUROBIOLOGY OF DISEASE

Dendritic ion channel trafficking and plasticity

(2010) Mala M. Shah et al.   TRENDS IN NEUROSCIENCES

Febrile seizures: Mechanisms and relationship to epilepsy

(2009) Céline M. Dubé et al.   BRAIN & DEVELOPMENT

Genetic mechanisms in idiopathic epilepsies

(2009) Yvonne G Weber et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Hyperpolarization-activated cation currents in human epileptogenic neocortex

(2009) Stephan Wierschke et al.   EPILEPSIA

Loss of Dendritic HCN1 Subunits Enhances Cortical Excitability and Epileptogenesis

(2009) Z. Huang et al.   JOURNAL OF NEUROSCIENCE

Genetic Enhancement of Thalamocortical Network Activity by Elevating  1G-Mediated Low-Voltage-Activated Calcium Current Induces Pure Absence Epilepsy

(2009) W. L. Ernst et al.   JOURNAL OF NEUROSCIENCE

Hyperpolarization-Activated Cation Channels: From Genes to Function

(2009) Martin Biel et al.   PHYSIOLOGICAL REVIEWS

Arrhythmia in Heart and Brain: KCNQ1 Mutations Link Epilepsy and Sudden Unexplained Death

(2009) A. M. Goldman et al.   Science Translational Medicine

Transcriptional Upregulation of Cav3.2 Mediates Epileptogenesis in the Pilocarpine Model of Epilepsy

(2008) A. J. Becker et al.   JOURNAL OF NEUROSCIENCE

Mouse models of humanKCNQ2andKCNQ3mutations for benign familial neonatal convulsions show seizures and neuronal plasticity without synaptic reorganization

(2008) Nanda A. Singh et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mechanisms of human inherited epilepsies

(2008) Christopher A. Reid et al.   PROGRESS IN NEUROBIOLOGY

Upregulated H-Current in hyperexcitable CA1 dendrites after febrile seizures

(2008) Jonas Dyhrfjeld-Johnsen   Frontiers in Cellular Neuroscience