TLR4 signaling is involved in the protective effect of propofol in BV2 microglia against OGD/reoxygenation

Hypoxia attenuates inflammatory mediators production induced by Acanthamoeba via Toll-like receptor 4 signaling in human corneal epithelial cells

(2012) Hong Pan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

FGF-2 inhibits TNF-α mediated apoptosis through up-regulation of Bcl2-A1 and Bcl-xL in ATDC5 cells

(2012) Hey-Ryun Kim et al.   BMB Reports

Caffeic acid ester fraction from Erigeron breviscapus inhibits microglial activation and provides neuroprotection

(2012) Shao-xia Wang et al.   Chinese Journal of Integrative Medicine

Neuroinflammation, Oxidative Stress and the Pathogenesis of Alzheimers Disease

(2012) Paula Agostinho et al.   CURRENT PHARMACEUTICAL DESIGN

Neuroprotective Effects of Pretreatment with Propofol in LPS-Induced BV-2 Microglia Cells: Role of TLR4 and GSK-3β

(2012) Bo Gui et al.   INFLAMMATION

Downstream Toll-like receptor signaling mediates adaptor-specific cytokine expression following focal cerebral ischemia

(2012) Famakin Bolanle et al.   Journal of Neuroinflammation

Exogenous Administration of PACAP Alleviates Traumatic Brain Injury in Rats through a Mechanism Involving the TLR4/MyD88/NF-κB Pathway

(2012) Shan-Shan Mao et al.   JOURNAL OF NEUROTRAUMA

Toll-like receptor 4 signaling is involved in PACAP-induced neuroprotection in BV2 microglial cells under OGD/reoxygenation

(2012) Xia Qin et al.   NEUROLOGICAL RESEARCH

Propofol-Induced Changes in Neurotrophic Signaling in the Developing Nervous System In Vivo

(2012) Jelena Popic et al.   PLoS One

Propofol improved neurobehavioral outcome of cerebral ischemia–reperfusion rats by regulating Bcl-2 and Bax expression

(2011) Hong-jie Xi et al.   BRAIN RESEARCH

Role of pro-inflammatory cytokines released from microglia in neurodegenerative diseases

(2011) Joshua A. Smith et al.   BRAIN RESEARCH BULLETIN

Microglia Phenotype Diversity

(2011) M. Olah et al.   CNS & Neurological Disorders-Drug Targets

Endotoxin-activated microglia injure brain derived endothelial cells via NF-κB, JAK-STAT and JNK stress kinase pathways

(2011) Rachid Kacimi et al.   Journal of Inflammation-London

Propofol post-conditioning induced long-term neuroprotection and reduced internalization of AMPAR GluR2 subunit in a rat model of focal cerebral ischemia/reperfusion

(2011) Haiyun Wang et al.   JOURNAL OF NEUROCHEMISTRY

The neuroprotective effect of propofol against brain ischemia mediated by the glutamatergic signaling pathway in rats

(2011) Jinsong Cai et al.   NEUROCHEMICAL RESEARCH

Anesthetic Propofol Reduces Endotoxic Inflammation by Inhibiting Reactive Oxygen Species-regulated Akt/IKKβ/NF-κB Signaling

(2011) Chung-Hsi Hsing et al.   PLoS One

Propofol’s effects on phagocytosis, proliferation, nitrate production, and cytokine secretion in pressure-stimulated microglial cells

(2011) Guangxiang Yu et al.   SURGERY

Effect of NF-κB Signaling on Apoptosis in Chronic Inflammation-Associated Carcinogenesis

(2010) H. Wang et al.   CURRENT CANCER DRUG TARGETS

Propofol protects the autophagic cell death induced by the ischemia/reperfusion injury in rats

(2010) Hae Sook Noh et al.   MOLECULES AND CELLS

Toll-like receptor 4 (TLR4), but not TLR3 or TLR9, knock-out mice have neuroprotective effects against focal cerebral ischemia

(2010) K. Hyakkoku et al.   NEUROSCIENCE

Changing Face of Microglia

(2010) M. B. Graeber   SCIENCE

Propofol has anti-inflammatory effects on alveolar type II epithelial cells

(2009) L. MA et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Microglial MyD88 signaling regulates acute neuronal toxicity of LPS-stimulated microglia in vitro

(2009) J.M. Dean et al.   BRAIN BEHAVIOR AND IMMUNITY

Propofol inhibits lipoteichoic acid-induced iNOS gene expression in macrophages possibly through downregulation of toll-like receptor 2-mediated activation of Raf-MEK1/2-ERK1/2-IKK-NFκB

(2009) Wen-Ta Chiu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The Role of Toll-like Receptors in Perinatal Brain Injury

(2009) Carina Mallard et al.   CLINICS IN PERINATOLOGY

Hypoxic stress up-regulates the expression of Toll-like receptor 4 in macrophages via hypoxia-inducible factor

(2009) So Young Kim et al.   IMMUNOLOGY

Toll-Like Receptor Stimulation Enhances Phagocytosis and Intracellular Killing of Nonencapsulated and Encapsulated Streptococcus pneumoniae by Murine Microglia

(2009) S. Ribes et al.   INFECTION AND IMMUNITY

Critical Role of TLR4 Response in the Activation of Microglia Induced by Ethanol

(2009) S. Fernandez-Lizarbe et al.   JOURNAL OF IMMUNOLOGY

Innate immune sensing and activation of cell surface Toll-like receptors

(2009) Richard I. Tapping   SEMINARS IN IMMUNOLOGY

MOLECULAR MECHANISMS OF PROPOFOL-INVOLVED SUPPRESSION OF NO BIOSYNTHESIS AND INDUCIBLE iNOS GENE EXPRESSION IN LPS-STIMULATED MACROPHAGE-LIKE RAW 264.7 CELLS

(2009) Chao-Jen Lee et al.   SHOCK

TLR3 and TLR4 are innate antiviral immune receptors in human microglia: Role of IRF3 in modulating antiviral and inflammatory response in the CNS

(2009) Hyeon-Sook Suh et al.   VIROLOGY

Mechanisms of Microglia-Mediated Neurotoxicity in a New Model of the Stroke Penumbra

(2008) V. Kaushal et al.   JOURNAL OF NEUROSCIENCE

Toll-like receptor signaling in endogenous neuroprotection and stroke

(2008) B.J. Marsh et al.   NEUROSCIENCE