Article
Horticulture
H. Gomez-Martinez, A. Bermejo, E. Zuriaga, M. L. Badenes
Summary: Apricot is a key fruit in the Mediterranean region, valued in the diets of Asian and Mediterranean countries. Polyphenols, the most abundant antioxidants in apricots, play a crucial role in defining fruit quality. The study identified the PPV resistant cultivar 'Goldrich' as the best for increasing antioxidants in apricot varieties.
SCIENTIA HORTICULTURAE
(2021)
Article
Pharmacology & Pharmacy
Mahmoud Abd-Elkareem, Mahmoud Soliman, Mokhless A. M. Abd El-Rahman, Nasser S. Abou Khalil
Summary: The study found that Nigella sativa seeds can alleviate MSG-induced renal toxicity in rats. Nigella sativa seeds improved oxidative stress and histopathological damage caused by MSG through their antioxidant and anti-apoptotic effects.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Environmental Sciences
Manal A. Alfwuaires
Summary: Galangin exhibited hepatoprotective effects by attenuating oxidative damage, inflammation, and apoptosis in rats with MTX-induced liver injury.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Green & Sustainable Science & Technology
Neva Karatas
Summary: Wild apricots exhibit variability in their morphological, nutritional, and nutraceutical characteristics. This study aimed to evaluate the fruits of different wild apricot genotypes for their total phenolics, antioxidants, and other bioactive compounds, which can be used in future breeding programs and sustainable food and pharmaceutical industries.
Article
Medicine, Research & Experimental
Meiwen Ding, Evelyn Tolbert, Mark Birkenbach, Reginald Gohh, Fatemeh Akhlaghi, Nisanne S. Ghonem
Summary: Treprostinil significantly reduced peak elevated serum creatinine levels and accelerated normalization relative to IRI-placebo. Treatment with treprostinil inhibited IRI-mediated renal apoptosis, mitochondrial oxidative injury, and the release of cytochrome c versus IRI-placebo. Overall, treprostinil reduced mitochondrial-mediated renal apoptosis, inhibited mitochondria fission, and promoted mitochondria fusion, thereby accelerating mitochondrial recovery and protecting renal proximal tubules from renal IRI.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Article
Medicine, Research & Experimental
Ayobami Dare, Mahendra L. Channa, Anand Nadar
Summary: This study demonstrated that L-egt, alone or in combination with metformin, has a protective effect on renal damage in a type-2 diabetes rat model, alleviating functional and structural derangements in the kidney. Treatment with L-egt significantly increased the expression of major antioxidant transcription factors and cytoprotective genes, while decreasing the expression of inflammatory genes in the kidney.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Article
Biochemistry & Molecular Biology
Mohammad Ashafaq, Sohail Hussain, Saeed Alshahrani, Rahimullah Siddiqui, Mohammad Intakhab Alam, Manal Mohamed Elhassan Taha, Yosif Almoshari, Saad S. Alqahtani, Abdulmajeed M. Jali, Hashim M. Aljohani
Summary: Cypermethrin (CPM), a toxic synthetic pyrethroid, causes neurotoxicity by inducing oxidative stress and neurochemical agitation in rats. Curcumin nanoparticles (NC), with potent antioxidant and anti-inflammatory properties, can attenuate CPM-induced neurotoxicity in rat brains. This study supports the use of NC as an effective treatment option for CPM-induced neurotoxicity.
Article
Medicine, Research & Experimental
Anamaria Magdalena Tomsa, Andreea Liana Rachisan, Stanca Lucia Pandrea, Andreea Benea, Ana Uifalean, Alina Elena Parvu, Lia Monica Junie
Summary: The study showed that even mild renal impairment may be closely related to oxidative stress markers, indicating that oxidative stress markers may be important biomarkers for early kidney damage.
EXPERIMENTAL AND THERAPEUTIC MEDICINE
(2021)
Article
Agriculture, Multidisciplinary
Sara Lombardo, Alessia Restuccia, Cristina Abbate, Umberto Anastasi, Stefania Fontanazza, Aurelio Scavo, Paolo Guarnaccia, Stefano La Malfa, Gaetano Pandino, Giovanni Mauromicale
Summary: The utilization of Trifolium subterraneum L. cover crops can increase mineral nutrients in the leaves and fruits of apricot trees, providing an eco-friendly alternative to synthetic herbicides and mineral N fertilizers in Mediterranean orchards.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Nutrition & Dietetics
Florinda Fratianni, Rosaria Cozzolino, Antonio d'Acierno, Maria Neve Ombra, Patrizia Spigno, Riccardo Riccardi, Livia Malorni, Matteo Stocchero, Filomena Nazzaro
Summary: The study evaluated the nutritional and antioxidant properties of ten apricot varieties cultivated in the Vesuvius area in Italy. The results showed that the total polyphenol and ascorbic acid content had a significant impact on the antioxidant activity, while beta-carotene did not. The analysis of volatile organic compounds (VOCs) revealed differences between the varieties and identified a specific compound that affected the antioxidant activity.
FRONTIERS IN NUTRITION
(2022)
Article
Plant Sciences
Eva Martinez-Ispizua, Angeles Calatayud, Jose Ignacio Marsal, Ruben Mateos-Fernandez, Maria Jose Diez, Salvador Soler, Jose Vicente Valcarcel, Mary-Rus Martinez-Cuenca
Summary: The study characterized 31 eggplant landraces from Spain with morphological descriptors and determined fruit quality in three selected landraces. Significant variability was observed in phenotypic and nutritional characteristics among the landraces, with fruit descriptors considered the most important and differences in antioxidant properties and sugar content highlighted.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Chemistry, Applied
Maja Berlic, Urska Jug, Tadej Battelino, Alenka Levart, Ivana Dimitrovska, Alen Albreht, Mojca Koros
Summary: This study found that antioxidant-enriched kindergarten menus contained more vegetables, nuts, and whole grain foods compared to standard menus, and their proximate composition and mineral content were more consistent with dietary recommendations. Additionally, the antioxidant capacity of these enriched menus was significantly higher, indicating that supplementing kindergarten meals with antioxidant-rich foods can improve dietary intake.
Article
Biochemistry & Molecular Biology
Sana Razhan M. Alsubaiei, Hanan A. Alfawaz, Ramesa Shafi Bhat, Afaf El-Ansary
Summary: Since there is no known cure for autism spectrum disorder (ASD), the aim of this study was to assess the possible danger of exposure to neurotoxic doses of propionic acid (PPA) and the nutritional protective effects of prebiotics and probiotics in a rat model. The results showed that PPA-induced ASD model presented increased oxidative stress and neuroinflammation; however, the groups treated with dietary therapies showed improvements in biochemical characteristics for oxidative stress and neuroinflammation. Therefore, these dietary therapies can be used as useful components to help prevent ASD.
Article
Environmental Sciences
Azibe Yildiz, Onural Ozhan, Ahmet Ulu, Tugba Dogan, Busra Bakar, Yilmaz Ugur, Elif Taslidere, Incilay Gokbulut, Seyhan Polat, Hakan Parlakpinar, Burhan Ates, Nigar Vardi
Summary: Due to its antioxidant and antimicrobial properties, sulfur dioxide (SO2) is commonly used in foods and beverages for preservation purposes. However, excessive SO2 intake may have adverse effects on male fertility. This study examined the effects of different concentrations of SO2 in apricot diets on rat testes. The results showed that high levels of SO2 (3500 ppm) in apricot diets led to male fertility problems through mechanisms such as oxidative stress, spermatogenic cell apoptosis, and inhibition of steroidogenesis.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Nutrition & Dietetics
Nusrat Jan, Sadaf Anjum, Sajad Mohd Wani, Sajad Ahmad Mir, A. R. Malik, Sajad Ahmad Wani, Dina S. Hussein, Rabab Ahmed Rasheed, Mansour K. Gatasheh
Summary: This study examined the effect of canning and storage on the physicochemical properties, mineral composition, antioxidant properties, and phenolic composition of apricot. The results showed that apricot pulp had higher levels of total soluble solids, titratable acidity, total sugars, and ascorbic acid, as well as higher contents of potassium, phosphorous, zinc, copper, iron, and manganese. Apricot pulp also had higher concentrations of bioactive compounds, phenolic content, and greater antioxidant properties. These findings suggest that apricot pulp can be a valuable source of nutrients, minerals, phytochemicals, and antioxidants for consumption purposes.
FRONTIERS IN NUTRITION
(2022)
Article
Biochemistry & Molecular Biology
Mustafa Erkan Ozgur, Ahmet Ulu, Canbolat Gurses, Imren Ozcan, Samir Abbas Ali Noma, Suleyman Koytepe, Burhan Ates
Summary: The present study aimed to determine the cytotoxicity of chromium(III) oxide micro particles (Cr2O3-Ps) in rainbow trout spermatozoa. The results showed that exposure to Cr2O3-Ps led to a decrease in spermatozoa velocities, antioxidant activities, and an increase in DNA damages. These findings are of significant importance for fish reproduction in aquatic environments.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Article
Chemistry, Physical
Gamze Dik, Ahmet Ulu, Orhan Orcun Inan, Selcuk Atalay, Burhan Ates
Summary: Enzyme immobilization using a novel magnetic carrier improved enzyme stability and activity. The immobilized enzyme displayed enhanced activity under a weak magnetic field and retained significant activity even after multiple cycles of use.
Article
Materials Science, Biomaterials
Aziz Pasahan, Resit Sevimli, Nilufer Kivilcim, Idil Karaca Acari, A. Sebnem Erenler, Selda Sezer, H. Turgut Durmat, Mustafa Huz, Tuba Unver, Turgay Seckin, Nusret Akpolat, Suleyman Koytepe, Ahmet Gultek, Burhan Ates, Ismet Yilmaz
Summary: “Implants with enhanced antibacterial and surface properties were prepared by replacing traditional titanium and titanium alloys in the field of biomedical materials. The chondroitin sulfate sol-gel coatings showed thermal stability and biocompatibility, making them a promising alternative for dental and orthopedic applications.”
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Oznur Dogan Ulu, Ali Kurucay, Burhan Ates, Ismail Ozdemir
Summary: In this study, six new Ag(I)-NHC complexes were synthesized and their structures were determined using spectroscopic methods and elemental analysis. These complexes showed good antibacterial activity against two bacterial strains and exhibited promising anticancer effects against a breast adenocarcinoma cell line.
Article
Pharmacology & Pharmacy
Lokman Hekim Tanriverdi, Onural Ozhan, Ahmet Ulu, Azibe Yildiz, Burhan Ates, Nigar Vardi, Haci Ahmet Acet, Hakan Parlakpinar
Summary: The MrgD receptor agonist ALA and Mas receptor agonist AVE0991 have been found to protect against hypertension induced by the renin-angiotensin system. In this study, ALA and AVE0991 were shown to lower blood pressure, improve vascular responses, and reduce inflammation and oxidative stress in Ang II-induced hypertension in rats.
FUNDAMENTAL & CLINICAL PHARMACOLOGY
(2023)
Article
Chemistry, Applied
Idil Karaca Acari, Gamze Dik, Busra Bakar, Ahmet Ulu, Yunus Onal, Burhan Ates
Summary: Immobilizing the alpha-amylase (Amy) enzyme using carbon and graphene quantum dot (QD) structures has been found to significantly enhance its catalytic activity and stability. This study investigated the immobilization of Amy enzyme using QDs prepared from Hypericum perforatum L. flowers (QD-1) and Hypericum capitatum seeds (QD-2). The immobilized enzymes exhibited higher activity efficiency and improved stability against various factors such as metal ions, organic solvents, and trypsin digestion. The findings suggest that these prepared carriers could be valuable for producing stable and active immobilized Amy enzymes for industrial applications.
TOPICS IN CATALYSIS
(2023)
Article
Biotechnology & Applied Microbiology
A. Kose, O. Ozhan, H. Parlakpinar, N. Vardi, A. Yildiz, Y. Turkoz, Z. Erdemli, Y. Bilgic, M. E. Sarihan
Summary: This study investigated the protective and therapeutic effects of agomelatine on liver regeneration in rats. The results showed that agomelatine has antioxidant and free radical scavenging properties, which can protect the liver after hepatectomy.
BIOTECHNIC & HISTOCHEMISTRY
(2023)
Article
Biotechnology & Applied Microbiology
Mehmet Akif Durak, Onural Ozhan, Bora Tetik, Azibe Yildiz, Zeynep Aksungur, Nigar Vardi, Yusuf Turkoz, Muharrem Ucar, Hakan Parlakpinar
Summary: This study investigated the effects of apocynin on sciatic nerve compression injury in rabbits. The findings suggest that apocynin treatment may contribute to the healing of sciatic nerve damage.
BIOTECHNIC & HISTOCHEMISTRY
(2023)
Review
Cardiac & Cardiovascular Systems
Mehmet Gunata, Hakan Parlakpinar
Summary: Heart failure (HF) is a critical health and economic burden that has been increasing in prevalence worldwide. Experimental HF models have provided valuable insights into the pathophysiology of HF and have been successful in studying its etiology and treatment. However, each animal model has its limitations, and none of them can fully capture all aspects of HF.
HEART FAILURE REVIEWS
(2023)
Article
Biochemistry & Molecular Biology
Busra Bakar, Emre Birhanli, Ahmet Ulu, Filiz Boran, Ozfer Yesilada, Burhan Ates
Summary: In this study, the feasibility of immobilizing a Trametes trogii laccase enzyme on Fe3O4/PVP magnetic nanoparticles (MNPs) was explored. The characterization and successful immobilization of laccase enzyme were verified. The Fe3O4/PVP/Lac showed remarkable thermal stability and good operational stability, with high decolorization efficiency of textile dyes in wastewater. This study suggests a promising way to solve the challenges of high cost and low operational stability in laccase-based dye removal.
BIOCATALYSIS AND BIOTRANSFORMATION
(2023)
Article
Biotechnology & Applied Microbiology
Necip Ermis, Zeynep Ulutas, Onural Ozhan, Azibe Yildiz, Nigar Vardi, Cemil Colak, Hakan Parlakpinar
Summary: C21 can prevent DOX-induced heart failure and has a similar effect as LOS, with the combined use of C21 and LOS being the most beneficial.
BIOTECHNIC & HISTOCHEMISTRY
(2023)
Article
Food Science & Technology
Gamze Dik, Busra Bakar, Ahmet Ulu, Sueleyman Koytepe, Burhan Ates
Summary: The study found that starch nanoparticles (SNPs) can be an effective carrier for immobilizing enzymes, improving the stability and reusability of xylanase (Xyl). The immobilized Xyl on SNPs exhibited enhanced pH stability, thermal stability, and operational stability. Furthermore, Xyl@SNPs demonstrated a lower Km value and increased substrate affinity, leading to improved clarity of orange juice.
