Role of 15-lipoxygenase/15-hydroxyeicosatetraenoic acid in hypoxia-induced pulmonary hypertension

15-Hydroxyeicosatetraenoic acid (15-HETE) protects pulmonary artery smooth muscle cells from apoptosis via inducible nitric oxide synthase (iNOS) pathway

(2011) Xiaowei Nie et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Role of the G-protein and tyrosine kinase--Rho/ROK pathways in 15-hydroxyeicosatetraenoic acid induced pulmonary vasoconstriction in hypoxic rats

(2010) Y. Wang et al.   JOURNAL OF BIOCHEMISTRY

Hypoxia suppresses Kv 2.1 channel expression through endogenous 15-hydroxyeicosatetraenoic acid in rat pulmonary artery

(2010) Lei Guo et al.   Journal of Physiological Sciences

The role of ERK1/2 in 15-HETE-inhibited apoptosis in pulmonary arterial smooth muscle cells

(2010) Jing Jiang et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

15-Hydroxyeicosatetraenoic acid (15-HETE) protects pulmonary artery smooth muscle cells against apoptosis via HSP90

(2010) Lei Zhang et al.   LIFE SCIENCES

Increased expression and altered subcellular distribution of PKC-δ and PKC-ɛ in pulmonary arteries exposed to hypoxia and 15-HETE

(2010) Xiaohong Li et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

15-HETE mediates sub-acute hypoxia-induced TRPC1 expression and enhanced capacitative calcium entry in rat distal pulmonary arterial myocytes

(2010) Shanshan Li et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

15-HETE protects rat pulmonary arterial smooth muscle cells from apoptosis via the PI3K/Akt pathway

(2010) Shuang Wang et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

ROCK pathway participates in the processes that 15-hydroxyeicosatetraenoic acid (15-HETE) mediated the pulmonary vascular remodeling induced by hypoxia in rat

(2009) Jun Ma et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Role of protein kinase C in 15-HETE-induced hypoxic pulmonary vasoconstriction

(2009) Lei Guo et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Inflammation, endothelial injury, and persistent pulmonary hypertension in heterozygous BMPR2-mutant mice

(2008) Yanli Song et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

15-HETE suppresses K+ channel activity and inhibits apoptosis in pulmonary artery smooth muscle cells

(2008) Yumei Li et al.   APOPTOSIS

Source of the elevation Ca2+ evoked by 15-HETE in pulmonary arterial myocytes

(2008) Xiaodong Zheng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Subacute hypoxia suppresses Kv3.4 channel expression and whole-cell K+ currents through endogenous 15-hydroxyeicosatetraenoic acid in pulmonary arterial smooth muscle cells

(2008) Lei Guo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Molecular pathogenesis of pulmonary arterial hypertension

(2008) Marlene Rabinovitch   JOURNAL OF CLINICAL INVESTIGATION

Hypoxia suppresses KV1.5 channel expression through endogenous 15-HETE in rat pulmonary artery

(2008) Xiaojie Chu et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS