Article
Oncology
Maria Lopez-Garzon, Paula Postigo-Martin, Angela Gonzalez-Santos, Manuel Arroyo-Morales, Alexander Achalandabaso-Ochoa, Antonio Manuel Fernandez-Perez, Irene Cantarero-Villanueva
Summary: Through an observational cross-sectional study, it was found that patients with CRC already exhibit signs of hyperalgesia and central sensitization at diagnosis, accompanied by deteriorated physical conditions and body composition, which could be worsened by subsequent treatments.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Health Care Sciences & Services
Denis G. Patterson, Derron Wilson, Michael A. Fishman, Gregory Moore, Ioannis Skaribas, Robert Heros, Soroush Dehghan, Erika Ross, Anahita Kyani
Summary: This study aims to assess the feasibility of using digital biomarkers collected from wearables during SCS treatment to predict pain and PRO outcomes. The results suggest that wearable biomarkers can be used to predict therapy outcomes in people with chronic pain, enabling continuous, real-time monitoring of patients during the use of implanted therapies.
NPJ DIGITAL MEDICINE
(2023)
Article
Medicine, General & Internal
Ahmed Alalawi, Valter Devecchi, Alessio Gallina, Alejandro Luque-Suarez, Deborah Falla
Summary: The aim of this study was to examine the differences in neuromuscular and psychological function in individuals with recurrent or chronic neck pain compared to healthy controls. The results showed that the participants with neck pain had higher neck disability, greater kinesiophobia, lower quality of life, slower and irregular neck movements, and less neck strength compared to the controls. In addition, the analysis revealed that a higher number of previous pain episodes and lower neck flexion strength were predictors of higher neck disability in the future.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Clinical Neurology
Christy Tomkins-Lane, Ruopeng Sun, Amir Muaremi, Patricia Zheng, Manoj Mohan, Ma Agnes Ith, Matthew Smuck
Summary: This study objectively characterized the daily physical activity of individuals with low back pain (LBP) using accelerometers and identified specific activity thresholds related to LBP. The findings showed that sedentary and light activity ranges were significantly different between the LBP group and healthy controls, while moderate to vigorous physical activity was not discriminative. These results can contribute to the development of LBP-specific physical activity interventions.
Article
Geriatrics & Gerontology
Emily Sin, Robin Shao, Tatia M. C. Lee
Summary: The study found that perceived loneliness is significantly associated with components of executive control functioning such as social cognition, planning and working memory, selective and divided attention, inhibition control, and sustained attention and motor inhibition. Specifically, planning and working memory may predict perceived loneliness, which is also linked to higher risk for major depression.
AGING & MENTAL HEALTH
(2021)
Article
Clinical Neurology
Suzanne Toren, Elias Diarbakerli
Summary: Adolescents with idiopathic scoliosis have reduced health-related quality of life compared to healthy controls. Minor differences in HRQoL were found when comparing different treatment groups for idiopathic scoliosis. Non-surgically treated scoliosis patients with larger curves had lower HRQoL as shown by lower SRS-22r scores.
EUROPEAN SPINE JOURNAL
(2022)
Article
Anesthesiology
Corey B. Simon, Trevor A. Lentz, Lindsay Ellis, Mark D. Bishop, Roger B. Fillingim, Joseph L. Riley, Steven Z. George
Summary: This study found that static pain sensitivity plays a larger role in resting pain among individuals with persistent low back pain, while dynamic pain sensitivity plays a larger role in movement-evoked pain. Static pain sensitivity explains an additional 9% variance in resting pain, and dynamic pain sensitivity explains an additional 10% to 12% variance in MEP. Future studies will confirm these relationships and further explore the impact of changes in pain sensitivity on clinical pain in adults with persistent low back pain.
CLINICAL JOURNAL OF PAIN
(2021)
Article
Neurosciences
Devonte Campbell, Bernadette Ann Murphy, James Burkitt, Nicholas La Delfa, Praveen Sanmugananthan, Ushani Ambalavanar, Paul Yielder
Summary: Alterations in neck sensory input from subclinical neck pain result in disordered sensorimotor integration. The study found that individuals with subclinical neck pain had a significantly larger COR gain and smaller VOR gain, suggesting an association between proprioceptive feedback and sensorimotor integration.
Article
Psychology, Multidisciplinary
Sameer Al-Ghamdi, Mamdouh M. Shubair, Khadijah Angawi, Jamaan Al-Zahrani, Abdulrahman Ali M. Khormi, Reem Falah Alshammari, Nawaf Safaq Alshammari, Raed Aldahash, Bander Yahya Otayf, Hayat Saleh Al-Zahrani, Manayir Sultan Aleshaiwi, Khaled K. Aldossari
Summary: The study found a significant positive association between neck/back pain and psychological distress/morbidity, with individuals experiencing neck/back pain having almost a 2.5 times greater risk of psychological problems. Females were also more likely to experience psychological distress/morbidity compared to males.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Juan Antonio Valera-Calero, Umut Varol
Summary: This study investigated the correlation between routinary physical activity and chronic neck pain severity indicators and salivary cortisol. The results showed that female sex, sedentary behaviors, and pain sensitivity were associated with higher cortisol levels. Worse disability, pain intensity, and pain pressure thresholds were associated with lower physical activity levels.
Article
Education, Scientific Disciplines
Victor Soukoulis, James Martindale, Megan J. Bray, Elizabeth Bradley, Maryellen E. Gusic
Summary: This study found a significant correlation between medical students' supervision ratings in EPA assessments and their clinical performance evaluations and CPX scores, supporting the use of supervision ratings in decisions about students' curricular progression.
Article
Orthopedics
Nils Lund, Olof Dahlqvist Leinhard, James M. Elliott, Gunnel Peterson, Magnus Borga, Peter Zsigmond, Anette Karlsson, Anneli Peolsson
Summary: This study aimed to investigate the relationship between dorsal neck muscle volume (MV) and muscle fat infiltration (MFI) and self-reported neck disability in patients with chronic Whiplash Associated Disorders (WAD). The results showed that participants with severe chronic WAD had higher MFI in the right trapezius compared to healthy controls. No other significant differences were found for MFI or MV. These findings contribute to the understanding of the association between MFI, muscle size, and self-reported neck disability in chronic WAD.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Article
Orthopedics
Suzanne J. Snodgrass, Peter Stanwell, Kenneth A. Weber, Samala Shepherd, Olivia Kennedy, Hannah J. Thompson, James M. Elliott
Summary: Muscle size and composition may play a role in chronic idiopathic neck pain, with individuals experiencing greater muscle volume and muscle fat infiltrate compared to asymptomatic controls.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Rheumatology
Christine Ballegaard, Marie Skougaard, Jorgen Guldberg-Moller, Christoffer Nissen, Kirstine Amris, Tanja S. Jorgensen, Lene Dreyer, Lars E. Kristensen
Summary: Obesity, hypertension, and CCI >= 1 were identified as prognostic factors for poorer treatment outcomes in PsA. Patients with PsA had higher disease burden at baseline compared to those with cutaneous psoriasis and healthy controls.
Review
Behavioral Sciences
Sophie Vervullens, Vincent Haenen, Lotte Meert, Mira Meeus, Rob J. E. M. Smeets, Isabel Baert, Michel G. C. A. M. Mertens
Summary: This article synthesizes all the studies on personal factors influencing pressure pain threshold (PPT) in healthy individuals. The results show that scapular position and gender have significant influences on PPT, while age and blood pressure have a weaker effect. There is preliminary or conflicting evidence for the influence of other variables, and more standardized research is needed.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Article
Clinical Neurology
Anne Smith, Mark Hancock, Susan O'Hanlon, Michael Krieser, Peter O'Sullivan, Flavia Cicuttini, Leon Straker, Brendan Adler, YuanYuan Wang, Jaro Karppinen, Dino Samartzis, Darren Beales, Pieter Coenen, Peter Kent
Summary: This study aimed to investigate the association between lumbar spine MRI findings and trajectories of low back pain (LBP) in young Australian adults. The results suggested that lumbar disc degeneration and herniation may be important contributors to disabling LBP in this population.
Article
Anesthesiology
Rob Waller, Philllip E. Melton, Michelle Kendell, Sophie Hellings, Erlend Hole, Alison Slevin, Jian Soares, Angela Jacques, Leon Straker, Darren Beales
Summary: This study investigates the heritability of musculoskeletal pain and pain sensitivity, finding significant heritability for musculoskeletal pain and pressure pain sensitivity, but not for cold pain sensitivity. The study highlights the need for further exploration of the genetic and environmental factors involved in the development of these pain disorders.
Article
Rehabilitation
Kwangil Kang, Kerrie Evans, Milena Simic, Paulo Ferreira, Aila Nica Bandong, Sonia Coates, Darren Beales, Trudy Rebbeck
Summary: The study evaluated the effect of an interactive educational workshop on specialist musculoskeletal physiotherapists' knowledge, beliefs, and clinical practice related to a proposed clinical care pathway. Results showed that the workshop improved knowledge, aligned beliefs with the pathway, and led to increased referrals back to primary physiotherapists. Overcoming barriers is necessary for widespread implementation.
MUSCULOSKELETAL SCIENCE AND PRACTICE
(2022)
Article
Clinical Neurology
Martin Rabey, Brendan Buldo, Magnus Duesund Helland, Courtenay Pang, Michelle Kendell, Darren Beales
Summary: This study identified three clusters of people with chronic low back pain based on their significant other interactions: those with low interaction, high supportive interaction, and high punishing interaction. These clusters differed in disability, mindfulness, depression, anxiety, stress, and pain catastrophising. These findings highlight the importance of considering significant other interactions in managing back pain.
BRITISH JOURNAL OF PAIN
(2022)
Article
Rehabilitation
Lore Dams, Elien van der Gucht, Vincent Haenen, Nele Devoogdt, Ann Smeets, Bart Morlion, Koen Bernar, Tessa De Vrieze, Niamh Moloney, An De Groef, Mira Meeus
Summary: This study aimed to examine the correlation between questionnaires evaluating signs and symptoms related to somatosensory functioning and quantitative sensory testing (QST) in breast cancer survivors. The results showed significant but weak correlations between the questionnaires and QST, suggesting that questionnaires may be insufficient for somatosensory profiling.
DISABILITY AND REHABILITATION
(2023)
Article
Rehabilitation
Aila Nica Bandong, Trudy Rebbeck, Martin Mackey, Michele Sterling, Joan Kelly, Carrie Ritchie, Andrew Leaver
Summary: This study aimed to explore health professionals' acceptance of guidelines for acute whiplash-associated disorders (WAD), and identify barriers and facilitators to adherence. The results revealed that acceptance of the guidelines was influenced by factors related to the guidelines themselves, practitioner and practice characteristics, and patient-related factors. Some professionals showed selective acceptance of key recommendations in the guidelines.
DISABILITY AND REHABILITATION
(2023)
Article
Rehabilitation
Danielle B. Stone, Trudy Rebbeck, Elizabeth C. Ward, James E. Elliott
Summary: This study explores the symptoms of dysphagia, dysphonia, and laryngeal hypersensitivity after whiplash and their impact on quality of life. The results indicate that these symptoms have negative effects and pose barriers to management. Better understanding of these symptoms is necessary for improved detection methods.
DISABILITY AND REHABILITATION
(2023)
Article
Rehabilitation
Eileen M. Boyle, Robyn E. Fary, Samantha Lee, Anton Mikhailov, Kerrie Evans, Trudy Rebbeck, Darren J. Beales
Summary: The study found that patients prefer matched or hybrid care pathways and feel that existing pathways do not meet their needs when pain persists. They suggest that implementation should focus on addressing individual needs.
MUSCULOSKELETAL SCIENCE AND PRACTICE
(2022)
Article
Biochemical Research Methods
A. L. Peek, T. J. Rebbeck, A. M. Leaver, S. L. Foster, K. M. Refshauge, N. A. Puts, G. Oeltzschner, MRS Expert Panel
Summary: The aim of this guideline is to provide evidence-based recommendations for using MEGA-PRESS to measure GABA levels. This widely used method at 3T is challenging and has a low signal-to-noise ratio. The guideline, developed by experts in MRS and guideline development, includes 23 recommendations across six domains and has been reviewed and approved by a panel of world leaders in MRS.
ANALYTICAL BIOCHEMISTRY
(2023)
Letter
Obstetrics & Gynecology
Darren Beales, Renata Asinelli, Marit Klokset, Lindsay O'Kane, Tonje Urstad, Emma Wise, Juliana Zabatiero, Judith Thompson, Jennifer Pontre, Robert Waller
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Anesthesiology
Trudy Rebbeck, Aila Nica Bandong, Andrew Leaver, Carrie Ritchie, Nigel Armfield, Mohit Arora, Ian D. Cameron, Luke B. Connelly, Roy Daniell, Mark Gillett, Rodney Ingram, Jagnoor Jagnoor, Justin Kenardy, Geoffrey Mitchell, Kathryn Refshauge, Simone Scotti Requena, Sarah Robins, Michele Sterling
Summary: This study evaluated the effectiveness of a risk-stratified clinical pathway of care for acute whiplash injury. The results showed that risk-stratified care did not improve patient outcomes, and the current pathway is not recommended.
Article
Anesthesiology
Michele Sterling, Tonny Andersen, Linda Carroll, Luke Connelly, Pierre Cote, Michele Curatolo, Genevieve Grant, Gwendolen Jull, Helge Kasch, Sophie Lykkegaard Ravn, Joy Macdermid, Eva-Maj Malmstrom, Trudy Rebbeck, Anne Soderlund, Julia Treleaven, David M. Walton, Hans Westergren
Summary: This study evaluated patient-reported outcome measures for whiplash associated disorders and recommended a core outcome set consisting of 6 domains: Physical Functioning, Perceived Recovery, Psychological Functioning, Quality of Life, Pain, and Work and Social Functioning. The recommendations were based on systematic reviews and consensus from an International Steering Committee.
Article
Rehabilitation
S. Macpherson, T. R. Rebbeck, S. Coates, K. Evans
Summary: This study examined the referral practices of recent graduate and experienced physiotherapists in primary care for musculoskeletal conditions, as well as their opinions on referral to specialist physiotherapists for people at risk of poor outcomes. The results showed that referral practices were influenced by specific diagnoses, complexity of presentations, confidence, self-awareness, and system-related factors. Experienced physiotherapists were more confident and specific in their referrals, and barriers to early referral included lack of awareness, health system factors, and impact on the patient.
MUSCULOSKELETAL SCIENCE AND PRACTICE
(2023)
Editorial Material
Rehabilitation
Trudy Rebbeck
EUROPEAN JOURNAL OF PHYSIOTHERAPY
(2023)
Article
Clinical Neurology
Darren Beales, Yi Ki Ho, James Lewin, Bianca Wen-Qi Loh, Amirah Binte Yusof, Sharon Grieve, Sonia Ranelli, David Holthouse, Tim Mitchell, Helen Slater
Summary: This study aimed to co-create a trustworthy infographic to share information about the lived experience of complex regional pain syndrome (CRPS). The infographic was completed using participatory design and rated highly for understandability. Participants indicated a significant willingness to share this infographic with others.
BRITISH JOURNAL OF PAIN
(2023)
