Mass magnetophoretic experiment applied to the separation of biocompatible magnetic nanoparticles with potential for magnetohyperthermia

A mass magnetophoretic experiment was developed to segregate nanoparticles according to their diameter and size dispersion. The samples were synthesized by the coprecipitation method and characterized using x-ray diffraction, high-resolution transmission electron microscopy and vibrating sample magnetometry. The mean diameter (standard deviation) showed a decrease of nanoparticle size (size dispersion) in the surface of the magnetic fluid sample submitted to the magnetophoretic experiment. Those effects were monitored by time-dependent apparent mass variation data, which could be important for scale-up applications. Magnetohyperthemia experiments were also performed, confirming our findings.