Journal
PHYSICAL REVIEW LETTERS
Volume 114, Issue 18, Pages -Publisher
AMER PHYSICAL SOC
DOI: 10.1103/PhysRevLett.114.188101
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Funding
- National Science Foundation [CBET-1132579, CBET-1436082]
- National Science Foundation Graduate Research Fellowship Program [DGE-1256259]
- BP graduate fellowship
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A mechanistic theory is developed to describe segregation in confined multicomponent suspensions such as blood. It incorporates the two key phenomena arising in these systems at low Reynolds number: hydrodynamic pair collisions and wall-induced migration. In simple shear flow, several regimes of segregation arise, depending on the value of a margination parameter M. Most importantly, there is a critical value of M below which a sharp drainage transition occurs: one component is completely depleted from the bulk flow to the vicinity of the walls. Direct simulations also exhibit this transition as the size or flexibility ratio of the components changes.
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