Article
Multidisciplinary Sciences
Milad Asgarpour Khansary, Saeed Shirazian, Gavin Walker
Summary: In this study, a molecular engineering methodology based on Raman spectra is proposed for optimizing the cocrystallization process. Through molecular dynamics simulations and theoretical calculations, the authors were able to build a process design space and found that this method provides valuable insights for nanoscale cocrystallization processes.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Multidisciplinary Sciences
Ke Ma, Jiaonan Sun, Harindi R. Atapattu, Bryon W. Larson, Hanjun Yang, Dewei Sun, Ke Chen, Kang Wang, Yoonho Lee, Yuanhao Tang, Anika Bhoopalam, Libai Huang, Kenneth R. Graham, Jianguo Mei, Letian Dou
Summary: In this study, stable two-dimensional perovskites were constructed using a series of pi-conjugated organic cations, allowing for delicate energy level tuning at the 2D/3D heterojunctions. This design reduced hole transfer energy barriers at the heterojunctions and within the 2D structures, leading to a decrease in charge accumulation at the interface. By leveraging these insights and the superior interface contact between conjugated cations and poly(triarylamine) (PTAA) hole transporting layer, a solar cell with a record-breaking power conversion efficiency of 24.6% was achieved, surpassing PTAA-based n-i-p devices. Furthermore, these devices demonstrated enhanced stability and reproducibility.
Article
Biochemistry & Molecular Biology
Hyungmin Jun, Xiao Wang, Molly F. Parsons, William P. Bricker, Torsten John, Shanshan Li, Steve Jackson, Wah Chiu, Mark Bathe
Summary: ATHENA is an open-source software that automatically renders single-stranded DNA scaffold routing and staple strand sequences for any target wireframe DNA origami, expanding the possibilities of designing 3D DNA-based assemblies. The software also allows external editing of sequences and provides atomic-level models for molecular dynamics, coarse-grained dynamics with oxDNA, and other computational chemistry simulation approaches.
NUCLEIC ACIDS RESEARCH
(2021)
Article
Materials Science, Multidisciplinary
Juan Peng, Lixin Li, Lin Li, Xiaofeng Liu
Summary: This study investigates the phase behavior of all-conjugated triblock copolymers and their correlation with optical properties. By adjusting molecular parameters, the researchers were able to control the phase transition between cocrystallization and microphase separation. The findings provide a foundation for the application of these copolymers in optoelectronic devices.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Chemistry, Physical
Lixin Li, Qingqing Zhao, Shuwen Chen, Zhiqun Lin, Juan Peng
Summary: The ability to control cocrystallization behavior through meticulous design and synthesis of multiblock copolymers can enhance charge transport properties, providing important guidance for the development of high-performance organic field-effect transistors (OFETs).
Article
Chemistry, Physical
Tianqi Niu, Yue-Min Xie, Qifan Xue, Sangni Xun, Qin Yao, Fuchao Zhen, Wenbo Yan, Hong Li, Jean-Luc Bredas, Hin-Lap Yip, Yong Cao
Summary: The chemical structure and concentration of spacers significantly affect the characteristics of 2D capping layers in 2D/3D perovskite heterostructures. Density functional theory calculations show that spacer modifications can alter energy-level alignments at 2D/3D interfaces, impacting charge-transfer characteristics. Strong interactions between EDBE cations and inorganic [PbI6](4-) slabs enable controlled deposition of high-quality QW structures with improved performance in 2D/3D PSCs.
ADVANCED ENERGY MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Heng Zhang, Daniel T. Yimam, Sytze de Graaf, Jamo Momand, Paul A. Vermeulen, Yingfen Wei, Beatriz Noheda, Bart J. Kooi
Summary: Strain engineering has attracted significant interest as a method to control functional properties. Recent research on heterostructures based on Bi2Te3, Sb2Te3, and GeTe has shown potential for a different type of strain engineering due to long-range mutual straining. The study reveals a fast relaxation process in the mica/Bi2Te3 system and long-range strain retention in GeTe and Sb2Te3 grown on or with Bi2Te3. Immediate strain relaxation by plastic deformation was observed, ruling out an elastic model for strain relaxation.
Review
Cell Biology
Zilong Li, Stephanie Portillo-Ledesma, Tamar Schlick
Summary: Chromosome conformation capture technologies provide frequency information for genomic region contacts, but do not directly reveal the 3D organization of chromatin. This article discusses computational methods for reconstructing chromatin 3D structures from 2D contact data, highlighting their biological insights and anchored mechanisms. Different reconstruction methods are compared, and a gene resolution approach based on Brownian dynamics and Monte Carlo sampling is presented.
CURRENT OPINION IN CELL BIOLOGY
(2023)
Review
Cell Biology
Anna Pawluchin, Milos Galic
Summary: This review discusses the differences in cell migration between 3D and 2D environments, and how these differences affect subcellular structures and motion patterns.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Haneul Kim, Gon Sup Kim, Sang-Hwan Hyun, Eunhye Kim
Summary: Neuromuscular diseases involve injury or dysfunction of neuromuscular tissue components. In vitro models have been developed to mimic the complex physical and biochemical microenvironments of human neuromuscular tissues, aiding the study and potential therapies for these diseases.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Chemistry, Physical
Huiling Zhong, Jun Huang, Jun Wu, Jianhang Du
Summary: Electrospun nanofibers are versatile and widely used in tissue engineering, mimicking the extracellular matrix and human tissue structures, suitable for various drug carriers and different functional needs.
Article
Chemistry, Multidisciplinary
Sin Kim Tang, Roger J. Davey, Pietro Sacchi, Aurora J. Cruz-Cabeza
Summary: This study systematically quantifies the impact of molecular flexibility on nucleation kinetics by comparing the nucleation rates of para substituted benzoic acids with flexible chain substituents. The importance of normalizing data to account for differing solubilities is highlighted, leading to more precise nucleation rate data. This research confirms the key role of intermolecular stacking interactions in determining relative nucleation rates and draws conclusions about conditions under which conformational change may become rate determining during a crystallization process.
Review
Pharmacology & Pharmacy
I Yuste, F. C. Luciano, E. Gonzalez-Burgos, A. Lalatsa, D. R. Serrano
Summary: Understanding the biology and behavior of human osteoblasts in vitro is crucial for developing research models that replicate bone structure and interactions accurately. Mimicking the bone microenvironment is challenging yet essential for clinical translation of novel medicines. Advanced technologies like 3D bioprinting and microfluidics bridge the gap between in vitro and in vivo models.
PHARMACOLOGICAL RESEARCH
(2021)
Article
Environmental Sciences
S. Bharathkumar, M. Sakar, J. Archana, M. Navaneethan, S. Balakumar
Summary: 3D particulate and 1D fiber structures of multiferroic bismuth ferrite were successfully integrated with 2D graphene oxide via ultrasonic-assisted chemical reduction, leading to effective interfacial engineering and improved photophysical properties. The developed hetero-morphological composites demonstrated enhanced stability and superior photocatalytic activity, with efficient charge separation and recombination resistance.
Article
Chemistry, Multidisciplinary
Dasol Kim, Youngsam Kim, Jin-Su Oh, Changwoo Lee, Hyeonwook Lim, Cheol-Woong Yang, Eunji Sim, Mann-Ho Cho
Summary: The reversible conversion between metavalent and covalent bonds is a promising basis for universal memory. However, the kinetic behavior of vacancies, which is crucial for the conversion, remains lacking in research due to experimental difficulties. In this study, the direct observation of the evolution of chemical states of vacancies clarifies their behavior by analyzing charge density distribution, electrical conductivity, and crystal structures. These findings provide insights into vacancy engineering in versatile materials.
Article
Chemistry, Physical
Nour Dissem, Najmeddine Ferhi, Thierry Maris, Adam Duong
Summary: Four new coordination polymers of mixed ligands have been synthesized and characterized. These polymers exhibit high thermal stability and show different structures, with hydrogen bonds playing a significant role in structure formation.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Organic
Aaron Gabriel Nunez Avila, Benoit Deschenes-Simard, E. Joseph Arnold, Mathieu Morency, Daniel Chartrand, Thierry Maris, Gilles Berger, Graeme M. Day, Stephen Hanessian, James D. Wuest
Summary: The nitrogen-rich compound 6-azidotetrazolo[5,1-a]phthalazine (ATPH) exhibits high polymorphism and diverse molecular organization due to its ability to form various N-H···N and C-H···N interactions. Crystal structures of ATPH reveal a polymorphic landscape with stacked sheets and herringbone packing. Exploring this landscape provides insights into fields such as energetic materials and molecular crystallization.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Rafal Wysokinski, Wiktor Zierkiewicz, Mariusz Michalczyk, Thierry Maris, Steve Scheiner
Summary: The arrangement and interaction of [PdCl4](2-) dianions in a crystal are studied and analyzed by quantum calculations. It is found that the interaction is highly repulsive with a large positive interaction energy, but the repulsion can be reduced by placing ligands nearby. When the ligands acquire a positive charge, it indicates an exothermic association. Increasing the charge on the counterions does not significantly enhance stability, and in fact, reduces the electrostatic attraction. The ability of counterions to promote the interaction is attributed to the hydrogen bonds they form with dianions.
Article
Chemistry, Organic
Sebastien Neron, Mathieu Morency, Liguo Chen, Thierry Maris, Dominic Rochefort, Radu Iftimie, James D. Wuest
Summary: Benzoquinones and 4,4'-diphenoquinones are attractive candidates for green carbon-based batteries. Although diphenoquinones are less explored, they have been synthesized and characterized. Experimental and computational studies show that diphenoquinones form chains or sheets in the solid state and have higher reduction potentials compared to benzoquinones. These findings are important for the development of carbon-based electrochemical devices.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Physical
Khaoula Chair, Cesar Augusto Luna Caceres, Sanil Rajak, Olivier Schott, Gustavo E. Ramirez-Caballero, Thierry Maris, Garry S. Hanan, Adam Duong
Summary: Carbon dioxide is an important trace gas in the atmosphere and its high concentration leads to serious issues. The use of solar energy for the photochemical reduction of CO2 is a promising strategy, but it faces challenges that need to be addressed for it to become a sustainable alternative for fuel and chemical generation. In this study, molecular photocatalysts were designed and demonstrated remarkable photocatalytic properties for CO2 reduction to CO. The mechanistic pathways of the reaction were investigated using a combination of structural characterization, experimental data, and density functional theory calculations.
ACS APPLIED ENERGY MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Norbert M. Villeneuve, Joshua Dickman, Thierry Maris, Graeme M. Day, James D. Wuest
Summary: Mixed crystals are formed when components of the structure are randomly replaced by analogues, and their properties can be adjusted by changing the ratio of components. However, there are no clear rules to predict when two compounds can form mixed crystals. Through various methods, it has been discovered that mixed crystals can have compositions and properties that vary continuously over wide ranges. The results of experiments and computational modeling show that predictions about mixed crystallization can be made reliably.
CRYSTAL GROWTH & DESIGN
(2023)
Article
Chemistry, Multidisciplinary
Adela Abidi, Emmanuelle Fortin, Kariane Larocque, Mohamed Essalhi, Nour Dissem, Daniel Chartrand, Thierry Maris, Adam Duong
Summary: In this paper, a facile method was reported for synthesizing eight structurally diverse compounds 1-8 with a hydrogen bonding functional group - diaminotriazine (DAT) along with pyridine and polyether groups for 1-4 and DAT linked via C-C bond to a 2-pyridone for 5-8. The successful synthesis of 1-8 was confirmed by various analytical techniques. The molecular structures and aggregations in the solid state of these compounds were elucidated using single crystal X-ray diffraction.
Article
Chemistry, Organic
Sebastien Neron, Mathieu Morency, Cedric Malveau, Thierry Maris, Radu Iftimie, James D. Wuest
Summary: This study explores the formation of diphenoquinhydrone, a compound similar to quinhydrone, and demonstrates that the intermolecular interactions in diphenoquinhydrone are stronger than in simple quinhydrone analogues. These findings illustrate that the principles of modular construction underlying the formation of classical quinhydrone can be applied to the synthesis of a broad range of hydrogen-bonded charge-transfer materials with designed component positioning.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Mohamed Essalhi, Midhun Mohan, Nour Dissem, Najmedinne Ferhi, Adela Abidi, Thierry Maris, Adam Duong
Summary: In this study, two new metal-organic frameworks with square and rhombic microchannels were synthesized for CO2 capture. These materials showed high CO2 uptakes and demonstrated strong non-covalent interactions with CO2 molecules. They also exhibited excellent CO2 selectivity for gas mixtures, with IRH-7 showing a remarkable increase in selectivity compared to IRH-6.
INORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Engineering, Multidisciplinary
Leonardo Raphael Zuardi, Cleide Lucia Araujo Silva, Eduardo Magalhaes Rego, Giovana Vacilotto Carneiro, Silvia Spriano, Antonio Nanci, Paulo Tambasco de Oliveira
Summary: In vitro study showed that titanium nanotopography modulates the osteogenic response and enhances the expression of alkaline phosphatase mRNA, activity, and osteopontin (OPN) levels. The presence of a blood clot tends to inhibit osteoblastic differentiation, but the coating of recombinant mouse (rm) BMP-7 on a nanostructured titanium surface promotes differentiation.
Article
Crystallography
Babacar Mbaye, Mouhamadou Birame Diop, Mouhamadou Sembene Boye, Thierry Maris, Aminata Diasse-Sarr, Libasse Diop
Summary: A dinuclear complex with two aqua-n-butyltinhydroxide dichloride bridges was obtained. The hydroxide bridges exhibited a static trans effect in the compound. Additional hydrogen bond patterns contributed to the formation of a 3D structure in the crystal.
JOURNAL OF CHEMICAL CRYSTALLOGRAPHY
(2023)
Article
Multidisciplinary Sciences
Amin Morteza Najarian, Filip Dinic, Hao Chen, Randy Sabatini, Chao Zheng, Alan Lough, Thierry Maris, Makhsud I. I. Saidaminov, F. Pelayo Garcia de Arquer, Oleksandr Voznyy, Sjoerd Hoogland, Edward H. H. Sargent
Summary: In this study, an organic scaffold was used to influence the geometric arrangement and electronic configuration of perovskite structures, resulting in the suppression of lone pair expression and templating symmetric octahedra. This design principle was extended to copper perovskite and quasi-two-dimensional systems. The resulting perovskite photodiodes exhibit improved performance compared to non-octahedral and lead analogues.
Article
Materials Science, Multidisciplinary
Yuxuan Che, Muhammad Rizwan Niazi, Ting Yu, Thierry Maris, Cheng-Hao Liu, Dongling Ma, Ricardo Izquierdo, Igor F. F. Perepichka, Dmytro F. F. Perepichka
Summary: We investigated nitrofluorene derivatives as adjustable electron-withdrawing groups for non-fullerene acceptors of the acceptor-donor-acceptor type. We reported their optoelectronic properties and performance in bulk heterojunction solar cells with PBDB-T donor polymer. Introducing up to four nitro groups to the fluorene unit resulted in deeper frontier orbital levels, reduced HOMO-LUMO gap, and red-shifted absorption bands. The best device performance was achieved with trinitrofluorene acceptors containing a solubilizing ester group, striking a balance between decreased voltage and increased photocurrent. The 2D brickwork packing of the tetranitrofluorene derivative, as determined by single crystal X-ray analysis, differed from the interpenetrating 3D network found in high-efficiency acceptors of the acceptor-donor-acceptor type, which might be the reason for the relatively poor charge transport properties. Steric hindrance between benzothiadiazole and nitrofluorene units could be alleviated by the use of furan linkers, which planarized the conjugated backbone but decreased solubility.
JOURNAL OF MATERIALS CHEMISTRY C
(2023)
Article
Chemistry, Organic
Johann O. E. Sosoe, Cedric Malveau, Thierry Maris, Radu Iftimie, James D. Wuest
Summary: In this study, we conducted a comprehensive investigation on benzene-1,2,4,5-tetramine (BTA), its oxidized form BTA-H-2, and related compounds using various methods. We obtained key insights into their properties and expect that these findings will accelerate the development of their applications in the field of materials science.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Engineering, Multidisciplinary
Leonardo Raphael Zuardi, Fabiola Singaretti de Oliveira, Roger Rodrigo Fernandes, Maria Paula Oliveira Gomes, Silvia Spriano, Antonio Nanci, Paulo Tambasco de Oliveira
Summary: This study evaluates the effects of exogenous BMP-7 on the differentiation of osteoblastic cells on a nanotextured Ti surface. The results show that the concentration of BMP-7 can alter the differentiation of osteoblastic cells on different surfaces. However, on the nanotextured Ti surface, the effects of BMP-7 are limited and do not significantly increase the mineralized matrix production by differentiated osteoblasts.