Article
Chemistry, Multidisciplinary
Toshiyuki Sasaki, Subham Ranjan, Satoshi Takamizawa
Summary: This study demonstrates a photoluminescent organosuperelastic crystal of a pure organic compound, 7-amino-4-methylcoumarin, with the coexistence of superelasticity and photoluminescence properties.
Article
Biochemistry & Molecular Biology
Taejin Kim, Kwan Bo Kim, Chang-Gu Hyun
Summary: The study aimed to investigate the melanogenetic potentials of natural 7-hydroxy coumarin derivatives in melanoma cells. The results showed that only 7-hydroxy 4-methylcoumarin (7H-4M) significantly stimulated melanin production and intracellular tyrosinase activity. Further investigations revealed that 7H-4M increased tyrosinase activity in a concentration-dependent manner and activated various molecular signaling pathways. Additionally, 7H-4M showed no adverse reactions in skin irritation tests, suggesting its potential in preventing pigmentation diseases.
Article
Chemistry, Multidisciplinary
Martina Jakovljevic Kovac, Maja Molnar, Tomislav Jednacak, Tomislav Balic, Jurica Novak
Summary: The development of an appropriate delivery system of active pharmaceutical ingredients (APIs) is crucial for disease treatment. Deep eutectic solvents (DESs) have been extensively studied for improved API delivery. In this study, two new DESs were prepared and characterized using lidocaine, 7-hydroxy-4-methylcoumarin, and lactic or levulinic acid. The solvents were characterized for their physical and chemical properties, and spectroscopic and thermal analysis confirmed their stability and intermolecular interactions.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Kinga Ostrowska, Anna Lesniak, Weronika Gryczka, Lukasz Dobrzycki, Magdalena Bujalska-Zadrozny, Bartosz Trzaskowski
Summary: A series of piperazine-containing derivatives of 6-acetyl-7-hydroxy-4-methylcoumarin were designed and synthesized to study their affinity for serotonin receptors. Compounds 4 and 7 exhibited excellent activity for 5-HT1A receptors with Ki values comparable to 8-OH-DPAT. The tested compounds showed differential intrinsic activities in agonist and antagonist modes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Mohamed S. El-Attar, Sadeek A. Sadeek, Sherif M. Abd El-Hamid, Hazem S. Elshafie
Summary: The aim of this study was to investigate the interaction between ciprofloxacin hydrochloride (CIP) and coumarin derivative 7-hydroxy-4-methylcoumarin (HMC) with Zr(IV) and synthesize different complexes. The results showed that the synthesized complexes exhibited good antibacterial activity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Sapna Ahuja, Sruthy Baburaj, Lakshmy Kannadi Valloli, Sarvar Aminovich Rakhimov, Kavyasree Manal, Aakrati Kushwaha, Steffen Jockusch, Malcolm D. E. Forbes, Jayaraman Sivaguru
Summary: Aryl-maleimides undergo a novel [2+4]-photodimerization instead of the expected [2+2]-photodimerization, and the stereochemistry of the photodimer formed complements the product observed under thermal conditions.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Spectroscopy
Simran Baweja, Prahlad Roy Chowdhury, Surajit Maity
Summary: The photoinduced tautomerization reactions via hydrogen atom transfer in 2,7-diazaindole isolated clusters with different solvent wires were computationally investigated. It was found that the ammonia clusters had lower reaction barriers compared to water clusters, and the barrier heights decreased with the lengthening of the solvent wire. The results suggest that ammonia is a better candidate for hydrogen transfer than water due to its higher gas-phase basicity.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Optics
Xucong Zhou, Huiting Li, Yu Zhao, Xixi Cui, Changzhe Zhang, Qingtian Meng
Summary: In this study, the solvent effect mechanism of the fluorescent probe DPPHC molecule was systematically investigated using density functional theory and time-dependent density functional theory. The results revealed that the DPPHC molecule exhibited significant intramolecular charge transfer characteristics instead of intramolecular proton transfer reactions in the excited state. With increasing solvent polarity, the hydrogen bond strength of the DPPHC molecule decreased, leading to a reduced likelihood of intramolecular proton transfer reactions.
JOURNAL OF LUMINESCENCE
(2022)
Article
Chemistry, Medicinal
Maria J. Matos, Paula Novo, Lucia Mayan, Iria Torres, Eugenio Uriarte, Matilde Yanez, Jose Angel Fontenla, Francesco Ortuso, Stefano Alcaro, Francesca Procopio, Maria Isabel Rodriguez-Franco, Cristina Val, Maria I. Loza, Jose Brea, Fernanda Borges, Dolores Vina
Summary: Psychiatric and neurological disorders affect millions of people worldwide, and current treatments are limited in their effectiveness. New therapeutic solutions are urgently needed to improve the lives of patients.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Svetlana A. Popova, Oksana G. Shevchenko, Irina Yu Chukicheva
Summary: In this work, a series of novel 9,10-dihydro-2H,8H-chromeno[8,7e][1,3]oxazine-2-on derivatives were synthesized and evaluated for their antioxidant properties. Among them, compound 7 with a phenyl fragment exhibited the highest membrane protective and antioxidant activities in various model systems.
CHEMICAL BIOLOGY & DRUG DESIGN
(2022)
Article
Spectroscopy
Prahlad Roy Chowdhury, Saurabh Khodia, Surajit Maity
Summary: This study computationally investigates the role of solvent molecules in the deactivation of photo-excited 2,7-diazaindole complexes. It reveals two competing deactivation pathways, proton transfer and hydrogen transfer, with similar energy barriers in water complexes and a preference for hydrogen transfer in ammonia complexes. These findings are significant for understanding the radiative and deactivation pathways of photo-excited solvated complexes of bio-relevant molecules.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Physical
Shusen Xiao, Zhangrong Lou, Debin Ji, Jinfeng Zhao
Summary: The intramolecular hydrogen bond of CHBT is strengthened in solvents with different polarities, particularly in nonpolar solvents. The phenomenon of excited state hydrogen bonding strengthening is more pronounced in nonpolar solvents. Furthermore, the ultrafast ESIPT behavior of CHBT is easier to clarify in nonpolar solvents through exploring potential energy curves and transition state energy profiles.
CHEMICAL PHYSICS LETTERS
(2021)
Article
Chemistry, Applied
Samarpita Das, Pooja Goswami, Vivek K. Verma, Harish K. Indurthi, Manoj Kumar, Biplob Koch, Deepak K. Sharma
Summary: Replacement of electron-donating N,N-dialkyl groups with four-membered azetidine has recently been used to improve the low fluorescence quantum yields of coumarin. In this study, 7-cycloalkylamino/alkyl amino analogues were synthesized and their fluorescence activity was compared to 7-azetidinyl-4-methylcoumarin. The synthesized analogues showed comparable fluorescence yields and biocompatibility in cell lines, and demonstrated successful application in biological imaging for living cells.
Article
Nanoscience & Nanotechnology
Qitong Mao, Siqi Liu, Yangkai Xiong, Daxiong Hu, Lei Huang, Zhiqiang Fang, Hao Jiang, Haomin Wang, Jipeng Li, Shuhong Mao, Guoqing Wang
Summary: A novel all-weather autocatalytic phosphorescence-fluorescence antifouling hydrogel was designed, which utilizes the phosphorescence effect of rare earth oxides to store energy and emit light at night, and stimulates fluorescence to prevent algae adhesion. After experiments and tests in marine environments, the hydrogel demonstrates excellent antifouling performance and algae suppression effect. Additionally, the hydrogel exhibits good adaptability in terms of tensile strength and algae coverage area in real marine environments.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Materials Science, Multidisciplinary
T. Ichii, N. Naka, K. Tanaka
Summary: Through experimental investigation, significant splitting of the 2P levels in the 1S-2P transitions of indirect excitons in diamond was discovered, attributed to the rotational symmetry breaking effect. This splitting led to a deviation in energy between the excitonic Rydberg constant and the 1S ground state, as well as an impact from the rotational symmetry breaking of the conduction band valleys.
Article
Chemistry, Physical
Noriyuki Minezawa
CHEMICAL PHYSICS LETTERS
(2015)
Article
Chemistry, Physical
Shinji Aono, Noriyuki Minezawa, Shigeki Kato
CHEMICAL PHYSICS LETTERS
(2010)
Article
Chemistry, Physical
Noriyuki Minezawa
CHEMICAL PHYSICS LETTERS
(2014)
Article
Chemistry, Physical
Noriyuki Minezawa, Nuwan De Silva, Federico Zahariev, Mark S. Gordon
JOURNAL OF CHEMICAL PHYSICS
(2011)
Article
Chemistry, Physical
Noriyuki Minezawa, Mark S. Gordon
JOURNAL OF CHEMICAL PHYSICS
(2012)
Article
Chemistry, Physical
Noriyuki Minezawa
JOURNAL OF CHEMICAL PHYSICS
(2013)
Article
Chemistry, Physical
Noriyuki Minezawa
JOURNAL OF CHEMICAL PHYSICS
(2014)
Article
Chemistry, Physical
Kurt R. Brorsen, Noriyuki Minezawa, Feng Xu, Theresa L. Windus, Mark S. Gordon
JOURNAL OF CHEMICAL THEORY AND COMPUTATION
(2012)
Article
Chemistry, Physical
Yu Harabuchi, Satoshi Maeda, Tetsuya Taketsugu, Noriyuki Minezawa, Keiji Morokuma
JOURNAL OF CHEMICAL THEORY AND COMPUTATION
(2013)
Article
Chemistry, Physical
Noriyuki Minezawa, Mark S. Gordon
JOURNAL OF PHYSICAL CHEMISTRY A
(2011)
Article
Chemistry, Physical
Albert DeFusco, Noriyuki Minezawa, Lyudmila V. Slipchenko, Federico Zahariev, Mark S. Gordon
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2011)
Article
Chemistry, Physical
Noriyuki Minezawa, Takahito Nakajima
JOURNAL OF CHEMICAL PHYSICS
(2019)
Article
Chemistry, Physical
Noriyuki Minezawa, Takahito Nakajima
JOURNAL OF CHEMICAL PHYSICS
(2020)
Meeting Abstract
Chemistry, Multidisciplinary
Mark Gordon, Kurt Brorsen, Noriyuki Minezawa, Spencer Pruitt
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2012)