Article
Food Science & Technology
Yanlong Han, Fuguo Jia, Shigang Bai, Yawen Xiao, Xiangyi Meng, Longwei Jiang
Summary: Nanoscale catechin/beta-cyclodextrin inclusion complex (CA/beta-CD IC) particles were prepared by nanoprecipitation method, and the effects of operating conditions on particle size were studied. The particles could be further reduced in size by adjusting parameters, with a high inclusion ratio and good stability. The nanoparticles showed controlled release behavior and potential applications in nano-functional foods.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Biochemical Research Methods
Hiroyuki Terashima, Mayuko Seki, Saki Watanabe, Atsushi Yamamoto, Sen-ichi Aizawa, Atsushi Taga, Ikko Mikami, Shuji Kodama
Summary: Catechin and epicatechin were separated by HPLC using a phenyl column and aqueous mobile phases containing β-cyclodextrin. The interaction between the compounds and β-cyclodextrin was confirmed, and the effect of fructose on the epimerization of the enantiomers was investigated. Additionally, a successful separation of catechins in green tea infusion was achieved using a gradient HPLC elution mode with β-cyclodextrin.
JOURNAL OF CHROMATOGRAPHY A
(2022)
Article
Biochemistry & Molecular Biology
Bogumila Urbanska, Hanna Kowalska, Karolina Szulc, Malgorzata Ziarno, Irina Pochitskaya, Jolanta Kowalska
Summary: The content of polyphenols in chocolate depends on raw materials and manufacturing parameters. Research shows that chocolates made from unroasted cocoa beans have the highest polyphenol content. Both the temperature and time at the conching stage significantly affect the content of polyphenols and the rheological properties of chocolate milk mass.
Article
Chemistry, Multidisciplinary
Chendi Zhan, Zenghui Lao, Yiming Tang, Qin Qiao, Guanghong Wei
Summary: The simulations showed that two enantiomeric catechins had a stronger disruptive effect on Aβ(42) protofibril compared to their stereo isomer epicatechin. The different protofibril-disruptive effects were mainly attributed to the steric effect caused by conformational differences.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Physical
S. Anitha, V Saranya, R. Shankar, V Sasirekha
Summary: The interaction between two stereoisomeric flavanols and bovine serum albumin (BSA) was studied using UV-Vis absorption and fluorescence spectroscopy. The results showed a strong binding affinity between flavanols and BSA at a single binding site, leading to static quenching of BSA fluorescence. Molecular docking and molecular dynamics simulation revealed that hydrophobic and hydrogen bond interactions were responsible for the binding between flavanols and BSA, resulting in a compact structure.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Nutrition & Dietetics
Emily P. Laveriano-Santos, Camila Arancibia-Riveros, Anna Tresserra-Rimbau, Sara Castro-Barquero, Ana Maria Ruiz-Leon, Ramon Estruch, Rosa Casas, Patricia Bodega, Mercedes de Miguel, Amaya de Cos-Gandoy, Jesus Martinez-Gomez, Carla Rodriguez, Gloria Santos-Beneit, Juan M. Fernandez-Alvira, Rodrigo Fernandez-Jimenez, Rosa M. Lamuela-Raventos
Summary: This study found that higher intake of flavonoids from cocoa-based products was associated with lower adiposity parameters and a lower probability of presenting abdominal obesity.
FRONTIERS IN NUTRITION
(2022)
Article
Chemistry, Applied
Longwei Jiang, Fenghui Wang, Mengyu Du, Cancan Xie, Xinyan Xie, Huajiang Zhang, Xiangyi Meng, Anqi Li, Tianyi Deng
Summary: In this study, nanoscale alpha-, beta-, gamma-cyclodextrin (CD)-metal-organic frameworks (MOFs) were successfully prepared using a solvothermal assisted ultrasound method. The CD-MOFs were used as nanocarriers to encapsulate catechin (CA), and their encapsulation capacities were evaluated. The results showed that the beta-CD-MOFs had the highest encapsulation capacity for CA. Characterization techniques such as SEM, FT-IR, XRD and DSC confirmed the formation of CA/CD-MOFs and the interaction between CA and CD-MOFs through hydrogen bonding and van der Waals forces. The encapsulation of CA within CD-MOFs provided it with protection against light, oxygen and temperature and improved its storage stability and bioavailability.
Article
Plant Sciences
Arif Atak, Zekiye Goksel, Yusuf Yilmaz
Summary: This study aimed to determine the contents of 3 major phenolic compounds in 22 different grape cultivars/hybrids from 2 breeding programs, and investigate phenolic changes in grape leaves related to powdery and downy mildew diseases. Results showed significant differences in phenolic contents among hybrids/cultivars and different grape parts, with seeds containing higher levels. Increased phenolic compounds were found in resistant/tolerant cultivars after powdery mildew disease, suggesting high phenolic content cultivars are recommended for breeding programs.
Article
Nutrition & Dietetics
Enrique Almanza-Aguilera, Daniela Ceballos-Sanchez, David Achaintre, Joseph A. Rothwell, Nasser Laouali, Gianluca Severi, Verena Katzke, Theron Johnson, Matthias B. Schulze, Domenico Palli, Giuliana Gargano, Maria Santucci de Magistris, Rosario Tumino, Carlotta Sacerdote, Augustin Scalbert, Raul Zamora-Ros
Summary: This study found a stronger correlation between urinary concentrations of catechin and epicatechin and acute intake of monomers, proanthocyanidins, and theaflavins, compared to habitual intake. Urinary concentrations of flavan-3-ols were weakly correlated with the intake of various foods. Additionally, correlations were stronger for epicatechin than for catechin in urine.
Article
Food Science & Technology
Chan Bai, Ping Xu, Wenyuan Qi, Qiulian Kong, Juguang Wang, Tao Liao, Guangquan Xiong
Summary: A sustained-release bio-preservative based on beta-cyclodextrin encapsulated eugenol was prepared through electron beam irradiation, optimized using response surface methodology with a Box-Behnken design to achieve high encapsulation efficiency. The inclusion complex showed enhanced stability and solubility of eugenol, prolonging the shelf life of weevers and maintaining food quality. Overall, the EU/beta-CD-g-AM inclusion complex is a promising approach for sustained-release preservation in food.
Article
Biochemistry & Molecular Biology
Zhi Xuan Low, Michelle Yee Mun Teo, Fariza Juliana Nordin, Firli Rahmah Primula Dewi, Vijayaraj Kumar Palanirajan, Lionel Lian Aun In
Summary: Curcumin (CUR) encapsulated within a beta-cyclodextrin (beta-CD) complex showed significantly improved water solubility and enhanced anticancer effects. The inclusion complex demonstrated reduced cancer cell migration and invasion rates, increased apoptosis rates, and inhibited colorectal cancer cell growth. Preliminary toxicity evaluation indicated the safety of this formulation for cancer therapy in humans.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Spectroscopy
Ye Li, Hongrui Liu, Chunyu Mu, Jiali Gu, Chun Li
Summary: This study investigated the interaction mechanism between ethoxyquin (EQ) and transporter protein before and after beta-cyclodextrin (beta-CD) encapsulation. The results showed that EQ formed complexes with bovine serum albumin (BSA) and affected its structure and environment. However, encapsulation in beta-CD reduced the binding ability of EQ to BSA and prevented adverse effects on BSA conformation.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Chemistry, Applied
Ismail Oguz Ozdemir, Orhan Karakaya, Umut Ates, Burhan Ozturk, Mansur Uluca, Celal Tuncer
Summary: The brown marmorated stink bug has become a major threat to hazelnut yield and quality due to its impact on secondary metabolites in hazelnut kernels, specifically affecting phenolics and fatty acids.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Biochemistry & Molecular Biology
Haojie Sha, Bo Cui, Chao Yuan, Yuhang Li, Li Guo, Pengfei Liu, Zhengzong Wu
Summary: The study developed pre-gelatinized starch-based orally disintegrating films (ODFs) containing catechin/13-cyclodextrin (CAT/13-CD) complex, which significantly improved the physicochemical properties of the films. The complex enhanced thermal stability and tensile strength, while reducing elongation at break. ODFs with CAT/13-CD showed acceptable in vitro disintegration time, antimicrobial activity against S. aureus and S. mutans, and excellent antioxidant capacity. The study suggests that the combination of ODFs and 13-CD complex has high potential for delivering natural active ingredients.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Plant Sciences
Benjamin Battistoni, Juan Salazar, Wladimir Vega, Diego Valderrama-Soto, Pablo Jimenez-Munoz, Ailynne Sepulveda-Gonzalez, Sebastian Ahumada, Isaac Cho, Claudio Sebastiano Gardana, Hector Morales, Alvaro Pena-Neira, Herman Silva, Jonathan Maldonado, Mauricio Gonzalez, Rodrigo Infante, Igor Pacheco
Summary: This study aimed to identify the QTL associated with flavan-3-ol content in Japanese plum fruits, and a novel major gene controlling the synthesis of flavan-3-ols was discovered. This has significant implications for understanding fruit quality, postharvest control, and human health promotion.
FRONTIERS IN PLANT SCIENCE
(2022)
Correction
Chemistry, Physical
Rahul V. Pinjari, Mickael G. Delcey, Meiyuan Guo, Michael Odelius, Marcus Lundberg
JOURNAL OF CHEMICAL PHYSICS
(2015)
Article
Chemistry, Multidisciplinary
Rahul V. Pinjari, Mickael G. Delcey, Meiyuan Guo, Michael Odelius, Marcus Lundberg
JOURNAL OF COMPUTATIONAL CHEMISTRY
(2016)
Article
Chemistry, Multidisciplinary
Satish S. Bhat, Vidyanand K. Revankar, Ayesha Khan, Rahul V. Pinjari, Marek Necas
CHEMISTRY-AN ASIAN JOURNAL
(2017)
Article
Chemistry, Physical
Meiyuan Guo, Erik Kallman, Lasse Kragh Sorensen, Mickael G. Delcey, Rahul V. Pinjari, Marcus Lundberg
JOURNAL OF PHYSICAL CHEMISTRY A
(2016)
Article
Chemistry, Physical
Kristjan Kunnus, Wenkai Zhang, Mickael G. Delcey, Rahul V. Pinjari, Piter S. Miedema, Simon Schreck, Wilson Quevedo, Henning Schroeder, Alexander Foehlisch, Kelly J. Gaffney, Marcus Lundberg, Michael Odelius, Philippe Wernet
JOURNAL OF PHYSICAL CHEMISTRY B
(2016)
Article
Chemistry, Physical
Meiyuan Guo, Lasse Kragh Sorensen, Mickael G. Delcey, Rahul V. Pinjari, Marcus Lundberg
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2016)
Article
Chemistry, Multidisciplinary
Satish S. Bhat, Vidyanand K. Revankar, Rahul V. Pinjari, S. Naveen, Chetana Bogar, Kishor Bhatd, Vitthal A. Kawadee
NEW JOURNAL OF CHEMISTRY
(2017)
Correction
Chemistry, Physical
Rahul V. Pinjari, Mickael G. Delcey, Meiyuan Guo, Michael Odelius, Marcus Lundberg
JOURNAL OF CHEMICAL PHYSICS
(2014)
Article
Chemistry, Physical
Rahul V. Pinjari, Mickael G. Delcey, Meiyuan Guo, Michael Odelius, Marcus Lundberg
JOURNAL OF CHEMICAL PHYSICS
(2014)
Article
Biochemistry & Molecular Biology
Jayshree K. Khedkar, Krishna K. Jagtap, Rahul V. Pinjari, Alok Kumar Ray, Shridhar P. Gejji
JOURNAL OF MOLECULAR MODELING
(2012)
Article
Biochemistry & Molecular Biology
Ishita A. Raja, Vivekanand V. Gobre, Rahul V. Pinjari, Shridhar P. Gejji
JOURNAL OF MOLECULAR MODELING
(2014)
Article
Chemistry, Multidisciplinary
Kirti D. Badave, Shalaka S. Patil, Ayesha A. Khan, Darbha Srinivas, Raymond J. Butcher, Rajesh G. Gonnade, Vedavati G. Puranik, Rahul V. Pinjari, Shridhar P. Gejji, Sandhya Y. Rane
NEW JOURNAL OF CHEMISTRY
(2014)
Article
Biology
Ajay S. Sawant, Sonali S. Kamble, Parshuram M. Pisal, Sanjay S. Sawant, Shrikant V. Hese, Kamini T. Bagul, Rahul V. Pinjari, Vinod T. Kamble, Rohan J. Meshram, Rajesh N. Gacche
Summary: The synthesized N-(4-(substituted)-3-(trifluoromethyl) phenyl) isobutyramides and their N-ethyl analogues have shown promising anticancer activity, as well as dual inhibitory effects on angiogenesis and oxidative stress. The compounds 8 L, 8q, 9n, and 9p exhibited higher inhibitory activity on cancer cell viability than standard methotrexate, and also showed potential to inhibit proangiogenic cytokines. Additionally, in silico molecular docking data provided structural rationale for observed TNF alpha inhibition, highlighting the potential of these derivatives as anticancer agents with multiple mechanisms of action.
COMPUTATIONAL BIOLOGY AND CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Satish S. Bhat, Vidyanand K. Revankar, Rahul V. Pinjari, Vijay Kumbar, Kishore Bhat, Vitthal A. Kawade
Summary: Two water-soluble ruthenium(II) polypyridyl complexes have been synthesized and characterized, and their structural, optical, and cellular imaging properties have been investigated. The complexes exhibit strong emission in aqueous solutions and show low toxicity towards human cancer and kidney cell lines. Fluorescence microscopy confirms their potential for cellular imaging applications.
INORGANIC CHEMISTRY COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Satish S. Bhat, S. Naveen, Vidyanand K. Revankar, N. K. Lokanath, Rahul V. Pinjari, Vijay Kumbar, Kishore Bhat
NEW JOURNAL OF CHEMISTRY
(2020)