Article
Materials Science, Multidisciplinary
Evgenii P. Barannik, Andrey A. Shiryaev, Thomas Hainschwang
Summary: High spatial resolution infra-red maps and profiles were obtained for two single crystal diamonds with prominent CO2 IR absorption peaks. The distribution of IR band positions, intensities and widths followed a regular pattern, suggesting the presence of impurities in the trapped CO2 influencing the observed features and shifts of CO2 bands. Although spectroscopic barometry of CO2 microinclusions in diamond may be subject to bias, it is still possible if Davydov splitting of the CO2-I nu(2) band is unequivocally observed.
DIAMOND AND RELATED MATERIALS
(2021)
Article
Physics, Multidisciplinary
Ofer Aharony, Gabriel Cuomo, Zohar Komargodski, Mark Mezei, Avia Raviv-Moshe
Summary: We study the low-energy behavior of Wilson lines in conformal gauge theories and find that certain defect operators can become marginal, leading to interesting renormalization group flows and screening effects by charged fields. This screening phenomenon is universal in large enough representations of Wilson lines. We observe that fixed-point mergers are associated with the onset of the screening instability. By studying various applications, we show that the screening of Wilson lines can occur through dimensional transmutation or generation of large scales.
PHYSICAL REVIEW LETTERS
(2023)
Review
Mathematics, Interdisciplinary Applications
Z. I. Djoufack, R. Abouem A. Ribama, J. P. Nguenang
Summary: This paper investigates the impurity-impurity and impurity-breather interactions associated with energy localization in a quantum 1D Klein-Gordon chain through analytical and numerical study. The nonlinear Schrodinger equation (NLSE) is obtained using Glauber's coherent states and a multiple time scale method. Resonant structures are found through the frequency spectrum around the critical impurity mass. The existence conditions of breather and impure localized mode are acquired, and the dynamics of the impurity mode can be controlled by the impurity mass. Validation of the analytical approach is achieved through excellent agreement with numerical simulation.
CHAOS SOLITONS & FRACTALS
(2023)
Article
Optics
Keyin Li, Siqi Zhu, Shibo Dai, Zhen Li, Hao Yin, Zhenqiang Chen
Summary: The electronic state and nonlinear optical properties in Y-shaped quantum dots were theoretically investigated by adjusting the shape and applying an electric field. The results showed that both the strength and orientation of the external electric field, as well as the shape of the Y-shaped quantum dots, significantly influenced the electronic state, optical absorption coefficients, and refractive index changes.
Article
Physics, Multidisciplinary
Grigory E. Astrakharchik, Luis A. Pena Ardila, Richard Schmidt, Krzysztof Jachymski, Antonio Negretti
Summary: The authors investigate the behavior of an ionic impurity in a weakly interacting gas of bosonic atoms and identify two main phases of a polaronic regime and a strongly correlated state with many bosons bound to the ion under weak interactions. The presence of strong interactions in a many-body quantum system can lead to exotic effects, and the competition of length scales in a simple setup can give rise to a highly correlated mesoscopic state. The findings are relevant to experiments using hybrid atom-ion setups in the ultracold regime, showing vastly different polaronic properties compared to neutral quantum impurities.
COMMUNICATIONS PHYSICS
(2021)
Article
Construction & Building Technology
Yi Han, Xiao-Yong Wang, Gui-Yu Zhang
Summary: In this study, alkali-activated slag (AAS) was prepared by adding dry ice as an admixture. The effects of dry ice on the engineering properties and microstructure of AAS were investigated. The results showed that dry ice prolonged the setting time of AAS and improved its compressive strength.
CONSTRUCTION AND BUILDING MATERIALS
(2023)
Article
Chemistry, Physical
Jinchang Xu, Bi-Xiao Wang, Danya Lyu, Tianwu Wang, Zhenyou Wang
Summary: The electrochemical ethanol oxidation reaction (EOR) and oxygen evolution reaction (OER) possess different reaction pathways, as revealed by detailed electrochemical studies and in situ Raman spectra. This study provides guidance for further catalyst design by uncovering the mechanism differences between EOR and OER.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2023)
Article
Chemistry, Physical
Do-Haeng Hur, Geun-Dong Song, Jeoh Han, Soon-Hyeok Jeon
Summary: This study demonstrates that using concentrated NaOH solutions to simulate the crevice environments of SGs is inappropriate, as the magnetite deposits were rapidly dissolved in the test solution, contradicting the actual conditions.
Article
Chemistry, Analytical
Animesh Roy, Muhammad Zakria Tariq, Moonwoo La, Dongwhi Choi, Sung Jea Park
Summary: In this study, a series of Co- and Ni-based hydroxide nanoflakes/nanowalls were fabricated on conductive Ni foam substrate via a simple and quick electrochemical deposition method. The experimental results showed that Co(OH)2@Ni nanostructures exhibited the lowest overpotential and maintained their morphology after 24 hours of chronopotentiometric test, making them the optimal electrocatalyst for OER.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Spectroscopy
Yukihiro Yoshimura
Summary: In this short review, we provide a brief overview of the history of ice polymorphism under high pressure and recent progress on impurity ices. We also discuss the unique roles of impurities in ice and their promising impacts on the new area of ice physics.
JOURNAL OF RAMAN SPECTROSCOPY
(2022)
Article
Engineering, Chemical
Ling-sheng Ke, Lei Zhang, Xiao-wei Zhang, Zong-an Li, Zhi-qiang Wang, De-hong Chen, Lin Zhou, Shi-ying Chen, Lin Zheng, Xi-ping Zhou
Summary: The theoretical distributions of medium-volatile impurities in distillates of terbium metal were discussed and verified through vacuum distillation experiments. Fe and Cu were identified as medium-volatile impurities, with low removal rates during the distillation process.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Chemistry, Analytical
Yuliya Generalova, Nadezhda Sipkina, Galina Alekseeva
Summary: The new compound malaben exhibits pronounced activity in treating non-alcoholic fatty liver disease and could potentially be used as a drug. Various impurities in the malaben sample were studied and identified using electrophoretic separation and HPLC-ESI/MS analysis techniques, providing structural elucidation for some of the impurities.
MICROCHEMICAL JOURNAL
(2021)
Article
Biology
William S. Y. Wong, Lukas Hauer, Paul A. Cziko, Konrad Meister
Summary: The research finds that the Antarctic scallop Adamussium colbecki possesses a unique micro-ridge structure that allows it to control underwater ice formation, preventing dangerous accumulation and firm attachment of ice. This special structure helps protect the scallops from anchor ice and may be a key trait for their survival in anchor ice zones.
COMMUNICATIONS BIOLOGY
(2022)
Article
Pharmacology & Pharmacy
Nafisah Al-Rifai, Anas Alshishani, Fouad Darras, Ola Taha, Shereen Abu-Jalloud, Lena Shaghlil, Yousef Al-Ebini
Summary: Impurity identification and profiling is crucial for drug quality control, especially for newly developed medications like solriamfetol. In this study, we identified, synthesized, and isolated eight process-related solriamfetol impurities, characterized them using spectroscopic and chromatographic techniques, and proposed their formation mechanisms. Additionally, we developed a rapid impurity analysis method based on ultrahigh-performance liquid chromatography with UV detection, which meets the method validation criteria set by the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use. This method is suitable for routine analysis of solriamfetol substances.
JOURNAL OF PHARMACEUTICAL ANALYSIS
(2023)
Article
Engineering, Marine
Petr Zvyagin, Ilia Pavlov, Tatiana Zvyagina
Summary: Testing physical models of ice-resistant marine structures in an ice tank is a method used for design validation. This paper presents a systematic approach to the photogrammetric analysis of scenes in model-scale conditions and measures the broken ice dimensions in model-scale experiments. The results show that the obtained morphometric information can be used to improve mechanical models of ice fracture and failure.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2022)
Article
Ophthalmology
Philippe Daull, Mourad Amrane, Dahlia Ismail, Georgi Georgiev, Lukasz Cwiklik, Christophe Baudouin, Andrea Leonardi, Gerhard Garhofer, Jean-Sebastien Garrigue
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS
(2020)
Article
Biochemistry & Molecular Biology
Agnieszka Olzynska, Alicja Wizert, Martin Stefl, D. Robert Iskander, Lukasz Cwiklik
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2020)
Article
Chemistry, Multidisciplinary
Agnieszka Olzynska, Waldemar Kulig, Heikki Mikkolainen, Tomasz Czerniak, Piotr Jurkiewicz, Lukasz Cwiklik, Tomasz Rog, Martin Hof, Pavel Jungwirth, Ilpo Vattulainen
Article
Ophthalmology
Riku O. Paananen, Tuomo Viitaja, Agnieszka Olzynska, Filip S. Ekholm, Jukka Moilanen, Lukasz Cwiklik
Article
Biochemistry & Molecular Biology
Daniela Glatzova, Harsha Mavila, Maria Chiara Saija, Tomas Chum, Lukasz Cwiklik, Tomas Brdicka, Marek Cebecauer
Summary: The research found that proline and glycine residues in the transmembrane segment of LAT can affect its localization and function by inducing a kink in the helix, and further reduce dependence on palmitoylation by replacing them with aliphatic amino acids.
Article
Chemistry, Physical
Mirza Wasif Baig, Marek Pederzoli, Mojmir Kyvala, Lukasz Cwiklik, Jiri Pittner
Summary: Halogenated and alkylated BODIPY derivatives are studied as potential photosensitizers for photodynamic therapy. Results show that derivatives containing bromine atoms have stronger spin-orbit couplings, although they are similar to alkylated derivatives at local minima. Both bromine atoms and alkyl moieties reduce the HOMO/LUMO gap, aiding in the efficiency of the photosensitizers.
JOURNAL OF PHYSICAL CHEMISTRY B
(2021)
Article
Chemistry, Physical
Petr Pospisil, Lukasz Cwiklik, Jan Sykora, Martin Hof, Gregory M. Greetham, Michael Towrie, Antonin Vlcek
Summary: The excited-state properties and dynamics of two 6-(dimethylamino)-2-acylnaphthalene dyes were studied using picosecond time-resolved IR spectroscopy in solvents of different polarity. The results showed a transition from an initial excited state to a distinct structure in polar/H-bonding solvents, indicating a significant role in observing dynamic fluorescence Stokes shift.
JOURNAL OF PHYSICAL CHEMISTRY B
(2021)
Article
Biochemistry & Molecular Biology
Kamila Riedlova, Tereza Dolejsova, Radovan Fiser, Lukasz Cwiklik
Summary: This study investigates the mechanism of action of bio-inspired peptides originating from colicins on bacterial membranes using a combination of molecular simulations and experiments. The results show that these peptides are stable in lipid membranes and can induce membrane defects, water permeation, and membrane poration. Experimental assays confirm the ability of the H1 peptide to disrupt membranes. These findings are important for understanding the antimicrobial mechanisms of natural bacteriocins and developing small bio-inspired peptides that can disrupt bacterial membranes.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
(2022)
Article
Biochemistry & Molecular Biology
Martin Schicht, Kamila Riedlova, Mercedes Kukulka, Wenyue Li, Aurelius Scheer, Fabian Garreis, Christina Jacobi, Friedrich Paulsen, Lukasz Cwiklik, Lars Braeuer
Summary: The ocular surface requires a stable tear film and local immune defense mechanisms to protect the eye. This study focuses on surfactant protein G (SP-G) and its potential role in wound healing and reducing tear film surface tension.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Pharmacology & Pharmacy
Kamila Riedlova, Maria Chiara Saija, Agnieszka Olzynska, Piotr Jurkiewicz, Philippe Daull, Jean-Sebastien Garrigue, Lukasz Cwiklik
Summary: Benzalkonium chloride (BAK) compounds are commonly used as preservatives and stabilizers in topical ophthalmic products. In chronic eye conditions, the adverse effects of BAKs can accumulate, making preservative-free eye drops preferable. However, certain longer-chain BAKs, like cetalkonium chloride, have therapeutic functions in promoting wound healing and tear film stability.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
(2023)
Article
Nanoscience & Nanotechnology
Paulina Chytrosz-Wrobel, Monika Golda-Cepa, Piotr Kubisiak, Waldemar Kulig, Lukasz Cwiklik, Andrzej Kotarba
Summary: The therapeutic function of biomaterial surface can be improved by the controlled release of biologically active molecules. Ultrasonic-assisted formation of nanoparticles with controlled size and morphology can be used for such functionalization. This study reported the synthesis of fluorouracil nanoparticles, a bioactive molecule used in anticancer therapy, and revealed the molecular-level picture of the cavitation bubble interface where the enrichment of fluorouracil molecules takes place. The proposed mechanism can be applied to other biologically relevant molecules, suggesting that the sonochemical method can be used for the controlled formation of their nanoparticles. The results indicate the potential practical implications of tailoring the surface of polymeric biomaterials via the embedment of nanoparticles as drug delivery systems.
ACS APPLIED NANO MATERIALS
(2023)
Article
Pharmacology & Pharmacy
Kamila Riedlova, Maria Chiara Saija, Agnieszka Olzynska, Katarina Vazdar, Philippe Daull, Jean-Sebastien Garrigue, Lukasz Cwiklik
Summary: The tear film lipid layer (TFLL) may serve as a reservoir for latanoprost, facilitating its prolonged release and potentially optimizing glaucoma treatment. These findings have significant implications for the development of new drug delivery systems targeting the TFLL.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Materials Science, Biomaterials
Paulina Chytrosz-Wrobel, Monika Golda-Cepa, Kamil Drozdz, Jakub Rysz, Piotr Kubisiak, Waldemar Kulig, Monika Brzychczy-Wloch, Lukasz Cwiklik, Andrzej Kotarba
Summary: This study investigates the effect of oxygen plasma treatment on the physicochemical properties of polyurethane surfaces and characterizes the polyurethane-water interfaces in detail through experiments and molecular dynamics simulations.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2023)
Meeting Abstract
Biophysics
Agnieszka Olzynska, Hanna Korolainen, Ilpo Vattulainen, Waldemar Kulig, Lukasz Cwiklik
BIOPHYSICAL JOURNAL
(2022)
Meeting Abstract
Biophysics
Maria Chiara Saija, Lukasz Cwiklik
BIOPHYSICAL JOURNAL
(2022)