Article
Chemistry, Physical
Shun Kataoka, Makoto Harada, Tetsuo Okada
Summary: When an aqueous solution freezes below the eutectic point, a freeze concentrated solution (FCS) is formed, with the pH playing a crucial role in the thermodynamics and kinetics of reactions. Research has shown that frozen aqueous NaCl exhibits uneven pH distribution, while buffered solutions and frozen aqueous glycerol result in uniform pH values.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2021)
Article
Multidisciplinary Sciences
E. Korotaev, M. M. Syrokvashin, I. Yu Filatova, A. Kalinkin, A. Sotnikov
Summary: The study of CuCr(0.99)Ln(0.01)S(2) solid solutions revealed that substitution of chromium with lanthanum or cerium atoms does not significantly affect the atomic charges of matrix elements, with copper atoms in monovalent state, chromium and lanthanide atoms in trivalent state, and sulfur atoms in divalent state. Additional oxidation forms of sulfur and copper atoms were found in the near-surface layers, with lanthanide states mainly localized near the conduction band bottom.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Multidisciplinary
Michele Pugini, Bruno Credidio, Irina Walter, Sebastian Malerz, Florian Trinter, Dominik Stemer, Uwe Hergenhahn, Gerard Meijer, Iain Wilkinson, Bernd Winter, Stephan Thurmer
Summary: The recent application of concepts from condensed-matter physics to photoelectron spectroscopy of liquid-phase systems enables the measurement of electronic energetics of liquids on an absolute scale. The authors connect the newly accessible energy level to the solution work function and demonstrate accurate measurements of concentration-dependent work functions in aqueous solutions under controlled conditions. This work marks the beginning of a new era in the characterization of the interfacial electronic structure of aqueous solutions and liquids more generally.
Article
Chemistry, Multidisciplinary
Michele Pugini, Bruno Credidio, Irina Walter, Sebastian Malerz, Florian Trinter, Dominik Stemer, Uwe Hergenhahn, Gerard Meijer, Iain Wilkinson, Bernd Winter, Stephan Thurmer
Summary: The recent application of condensed-matter physics concepts to photoelectron spectroscopy (PES) of liquid-phase systems has allowed for the measurement of electronic energetics of liquids. The vertical ionization energies (VIEs) of liquid water and aqueous solutions can now be accurately determined and referenced to the local vacuum level. This work discusses the connection between these energies and the solution work function and demonstrates the accurate measurement of concentration-dependent work functions for an aqueous solution.
Article
Green & Sustainable Science & Technology
Binchuan Li, Rongxuan Zhou, Jianshe Chen, Daxue Fu, Kuiren Liu, Mingxin Li, Wubin Li, Qing Han
Summary: In this study, cationic membrane electrolysis was employed for the recovery of copper from thiosulfate solution. By systematically investigating the operational parameters, high recovery efficiency and low energy consumption were achieved while avoiding the decomposition of thiosulfate ions. This method offers a green and economical approach for metal recovery.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Chemistry, Multidisciplinary
Euihyun Lee, Carlos R. Baiz
Summary: This study characterizes the interactions between DMSO and water, showing that DMSO disrupts the hydrogen bond networks and this disruption increases with decreasing temperature.
Article
Physics, Fluids & Plasmas
David A. Faux, Ors Istok, Arifah A. Rahaman, Peter J. McDonald, Eoin McKiernan, Dermot F. Brougham
Summary: A Brownian shell model is proposed to describe the random rotational motion of a uniform particle density spherical shell, and it is validated by molecular dynamics simulations. The model is applied to proton spin rotation in aqueous paramagnetic ion complexes, and an expression for the Larmor-frequency-dependent nuclear magnetic resonance spin-lattice relaxation rate T1-1(co) is obtained. The Brownian shell model significantly improves existing particle-particle dipolar models without adding complexity, allowing for fits to experimental T-1 1(co) dispersion curves without arbitrary scaling parameters.
Article
Multidisciplinary Sciences
Quanquan Pang, Jiashen Meng, Saransh Gupta, Xufeng Hong, Chun Yuen Kwok, Ji Zhao, Yingxia Jin, Like Xu, Ozlem Karahan, Ziqi Wang, Spencer Toll, Liqiang Mai, Linda F. Nazar, Mahalingam Balasubramanian, Badri Narayanan, Donald R. Sadoway
Summary: We have developed a bidirectional, rapidly charging aluminium-chalcogen battery using a molten-salt electrolyte and a positive elemental-chalcogen electrode. This battery offers high charging rates, stability during cycling, low cost, recyclability, and fire resistance.
Article
Chemistry, Physical
Jana Madejova, Martin Barlog, Lubos Jankovic, Michal Slany, Helena Palkova
Summary: Organo-montmorillonites are highly attractive materials with wide application potential. This study reported the structural, vibrational, and thermal characteristics of two series of alkylammonium- and alkylphosphonium-montmorillonites for the first time. It was found that phosphonium-based montmorillonites had higher interlayer space expansion and higher decomposition rate temperature compared to their ammonium counterparts.
APPLIED CLAY SCIENCE
(2021)
Article
Multidisciplinary Sciences
Emilia Dzien, Dorota Dudek, Danuta Witkowska, Magdalena Rowinska-Zyrek
Summary: The membrane environment has a significant impact on the structure and coordination mode of biologically relevant metal ions, including Cu(II) coordination to amylin analogues. The presence of the amylin C-terminus reduces its affinity for copper(II), while in membrane-mimicking solution, the Cu(II) affinities of amylin analogues are lower than in water.
SCIENTIFIC REPORTS
(2022)
Article
Energy & Fuels
Ram R. Ratnakar, Vivek Chaubey, Birol Dindoruk
Summary: In this study, a machine learning based workflow was developed to estimate the solubility of CO2 in brine under different salt mixtures, pressure, and temperatures. Extensive experimental observations were used to test the performance of predictive models and workflow, and key features of brine components with significant contributions were identified.
Article
Engineering, Chemical
Guiping Zhu, Yating Wang, Qilan Huang, Ru Zhang, Ding Chen, Shixiong Wang, Xiangjun Yang
Summary: In this study, an emulsion liquid membrane (ELM) was successfully used for the selective separation of copper and nickel in ammonia solution, and the critical factors affecting the separation were systematically investigated. The results demonstrate the effective separation of copper (II) from ammonia solution using the ELM method. Furthermore, the study reveals the difference in reaction kinetics as the main reason for the selective separation of copper (II) and nickel (II) in ammonia solution.
MINERALS ENGINEERING
(2022)
Article
Chemistry, Applied
Tatiana D. Nekipelova, Evgenii N. Khodot, Olga N. Klimovich, Anna V. Shibaeva, Elena N. Timokhina, Galina Golovina, Alexey A. Kostyukov, Vladimir A. Kuzmin
Summary: The spectral, luminescent and photochemical properties of a series of hetarylazo dyes with dihydroquinoline and tetrazole moieties were investigated in aqueous solutions at various pH values. The study revealed the specific fluorescence behavior of the dyes in acidic solutions and the important role of proton transfer reactions in their transformations.
Article
Physics, Applied
Timur S. Batukaev, Igor V. Bilera, Galina V. Krashevskaya, Yuri A. Lebedev, Iren L. Epstein
Summary: Gas chromatography, optical emission spectroscope, and high-speed video camera were used to study the microwave discharge in aqueous solution of ethanol. The main gas products were H-2, CO, C2H2, CH4, C2H4, with H-2 and CO being predominant. The composition of the reaction products was independent of incident power and ethanol content, but the total flow rate of gas products increased with an increase in power and ethanol content. The best characteristics of hydrogen production were: flow rate of 3240 mL/min, concentration of 59 vol% at the discharge outlet, and maximum energy efficiency of 324 NL/kWh.
PLASMA PROCESSES AND POLYMERS
(2023)
Article
Chemistry, Inorganic & Nuclear
Kamila Stokowa-Soltys, Karolina Kierpiec, Robert Wieczorek
Summary: In many cases, human microbiota are associated with cancer progression. It was concluded that the bacterium Fusobacterium nucleatum increases neoplastic changes. Recent studies show that metal complexes with outer membrane protein fragments can promote the formation of reactive oxygen species (ROS), leading to oxidative stress and cell damage. This paper characterizes the formation of copper(ii) complexes with fragments of adhesin YadA from F. nucelatum and demonstrates their ability to produce ROS. Importantly, the free ligands are efficient DNA-cleaving agents.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Inorganic & Nuclear
Janos P. Meszaros, Gabor Nemeti, Jelena M. Poljarevic, Tamas Holczbauer, Nora V. May, Eva A. Enyedy
Summary: The solution speciation and reactivity of Rh(η5-C5Me5), Ru(η6-p-cymene), and Ru(η6-toluene) complexes with 2,4-pyridinedicarboxylic acid and 2-picolinic acid were studied and compared. X-ray diffraction analysis revealed structures of the complexes, showing different geometries and stability preferences. Complexes with 2,4-pyridinedicarboxylic acid were found to form more stable complexes compared to those with 2-picolinic acid, especially with Ru(η6-arene) complexes.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Nora V. May, Attila Jancso, Eva A. Enyedy
Summary: Copper(II) complexes of thiosemicarbazones have been found to exhibit anticancer properties and their interaction with human serum albumin (HSA) can be influenced by blood transport proteins. The study revealed weak-to-moderate binding strength of the TSC complexes with HSA and observed molecular changes through spectral analysis during the binding process.
Article
Chemistry, Inorganic & Nuclear
Szilvia Bunda, Nora May, Dora Bonczidai-Kelemen, Antal Udvardy, H. Y. Vincent Ching, Kevin Nys, Mohammad Samanipour, Sabine Van Doorslaer, Ferenc Joo, Norbert Lihi
Summary: Copper(II) complexes formed with sulfonated salan ligands exhibit excellent binding ability and stability, especially when introducing a cyclohexyl moiety. The complexes also show moderate catalytic activity in the Henry reaction, with the best yield achieved by complexes of PrHSS and BuHSS. Despite lower metal binding ability compared to cyclohexyl counterparts, these complexes possess larger spin density on the nitrogen nuclei, affecting their catalytic activity.
INORGANIC CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Tatsiana V. Petrasheuskaya, Debora Wernitznig, Marton A. Kiss, Nora V. May, Dominik Wenisch, Bernhard K. Keppler, Eva Frank, Eva A. Enyedy
Summary: The study synthesized and characterized terminal N-mono- and dimethylated derivatives of an estrone-salicylaldehyde thiosemicarbazone hybrid and their highly cytotoxic Cu(II) complexes, as well as simpler structurally related analogues. The dimethylation of the derivatives led to more stable complexes in a series of ligands, exhibiting significant inhibitory effects on 3D spheroids of various human cancer cells.
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Eva A. Enyedy, Tatsiana Petrasheuskaya, Marton A. Kiss, Debora Wernitznig, Dominik Wenisch, Bernhard K. Keppler, Gabriella Spengler, Nora May, Eva Frank, Orsolya Domotor
Summary: The study investigated the solution chemical properties and biological activities of a novel tridentate salicyaldehyde semicarbazoneestrone hybrid and a related bicyclic compound. The compounds showed relatively high stability, efficient gallium binding, significant cytotoxicity against cancer cells, and dissociation at physiological pH.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Marton A. Kiss, Miroslav Perina, Vaclav Bazgier, Nora V. May, Adam Baji, Radek Jorda, Eva Frank
Summary: Steroid research is focusing on preparing modified derivatives with altered receptor binding and bioactivity. Results show that new compounds can inhibit androgen receptor activity and regulate gene expression in prostate cancer cells.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2021)
Article
Chemistry, Inorganic & Nuclear
Tibor Csupasz, Norbert Lihi, Zsuzsa Fekete, Antonia Nagy, Richard Botar, Viktoria Forgacs, Dezso Szikra, Nora Veronika May, Gyula Tircso, Ferenc Krisztian Kalman
Summary: In this study, two Cu(ii) complexes formed from the CB-15aneN(5) ligand and its bifunctional derivative were thoroughly characterized. The results showed that these Cu(ii) chelates have high thermodynamic stability, fast complexation, and moderate inertness under harsh conditions. The radiolabeling experiments demonstrated the fast complexation even at low concentrations. Based on these findings, the CB-15aneN(5) ligand family is an excellent platform for Cu(ii) complexation in radiotheranostics.
INORGANIC CHEMISTRY FRONTIERS
(2022)
Article
Chemistry, Physical
Tatsiana V. Petrasheuskaya, Ferenc Kovacs, Gabriella Spengler, Nora V. May, Eva Frank, Eva A. Enyedy
Summary: The effects of complexation of 2-aminophenol and 2-aminoestradiol with divalent metal ions on their physico-chemical and biological properties were investigated. It was found that complexation with Cu(II) ions resulted in higher stability and increased cytotoxicity against cancer cells. Moreover, complexation with Cu(II) ions also enhanced antioxidant activity and percentage of apoptotic cells.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Oncology
Vivien Posa, Alessia Stefanelli, Julia H. Bormio Nunes, Sonja Hager, Marlene Mathuber, Nora May, Walter Berger, Bernhard K. Keppler, Christian R. Kowol, Eva A. Enyedy, Petra Heffeter
Summary: In addition to zinc, iron and copper also play a role in the mode of action and resistance development of COTI-2 and its derivatives. COTI-NMe2 is discovered to be a new drug candidate with improved anticancer activity and resistance profile. The study reveals that COTI-2 forms stable complexes with copper and glutathione, making it a substrate for the resistance efflux transporter ABCC1. Furthermore, the interaction of COTI-2 and its derivatives with iron, copper, and zinc ions is characterized, and their activities against drug-resistant cancer cells are investigated.
Article
Biochemistry & Molecular Biology
Tamas Pivarcsik, Vivien Posa, Hilda Kovacs, Nora May, Gabriella Spengler, Szonja P. Posa, Szilard Toth, Zeinab Nezafat Yazdi, Csilla Ozvegy-Laczka, Imre Ugrai, Istvan Szatmari, Gergely Szakacs, Eva A. Enyedy
Summary: This article investigates a novel 5-nitro-8-hydroxyquinoline-proline hybrid and its Rh(eta(5)-C5Me5) and Ru(eta(6)-p-cymene) complexes, which have excellent solubility in water and show inhibitory effects on sensitive and multidrug-resistant cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Tatsiana Petrasheuskaya, Ferenc Kovacs, Nora Igaz, Andrea Ronavari, Balint Hajdu, Laura Bereczki, Nora May, Gabriella Spengler, Bela Gyurcsik, Monika Kiricsi, Eva Frank, Eva A. Enyedy
Summary: A series of novel estradiol-based salicylaldehyde (thio)semicarbazones and their Cu(II) complexes were synthesized and characterized. The Cu(II)-estradiol-semicarbazone complex structure was determined by X-ray crystallography. The Cu(II) complexes of estradiol-TSC and its N,N-dimethyl derivative showed high cytotoxicity against cancer cells and significant activity against Staphylococcus aureus bacteria strain. Estradiol-TSCs exhibited efficient antioxidant activity, which was decreased by complexation with Cu(II) ions. The exchange of estrone moiety to estradiol did not significantly affect the physicochemical and biological properties.
Article
Chemistry, Inorganic & Nuclear
Nora May, Niloofar Bayat, Kende Attila Beres, Petra Bombicz, Vladimir M. Petrusevski, Gyorgy Lendvay, Attila Farkas, Laszlo Kotai
Summary: A hemipyridine solvate of bis(pyridine)silver(I) perchlorate was prepared and characterized by single crystal X-ray analysis and vibrational spectroscopy. The solvate structure is isomorphic with the analogous permanganate complex. The stoichiometric ratio of the monomer [Agpy(2)ClO(4)] and the solvent pyridine is 1:0.5, and the solvate pyridine occupies 18.0% of the volume of the unit cell.
Article
Chemistry, Multidisciplinary
G. Tamas Gal, Nora May, Laszlo Trif, Judith Mihaly, Petra Bombicz
Summary: This study reported the crystal structure of clopamide drug and its copper (II) complexes. By growing single crystals and analyzing molecular arrangements, the authors revealed the structural landscape of different polymorphs and solvatomorphs. The systematic comparison of crystal arrangements contributes to a better understanding of structure-directing effects and provides strategies to control molecular self-assembly.
Article
Chemistry, Inorganic & Nuclear
Janos P. Meszaros, Veronika F. S. Pape, Gergely Szakacs, Gabor Nemeti, Mark Denes, Tamas Holczbauer, Nora V. May, Eva A. Enyedy
Summary: A series of half-sandwich polypyridyl complexes were synthesized and compared for their structural, cytotoxic, and aqueous solution behavior. Introduction of methyl groups near coordinating nitrogen atoms affected steric congestion and changed ligand plane angles. The complexes showed high stability in solution, with Ru complexes susceptible to slow, irreversible decomposition in light exposure.
DALTON TRANSACTIONS
(2021)
Article
Chemistry, Inorganic & Nuclear
Zoltan Somosi, Nora May, Daniel Sebok, Istvan Palinko, Istvan Szilagyi
Summary: A catalytic antioxidant composite was prepared by adsorbing redox active metal complexes and polyelectrolytes on layered double hydroxide nanoclay, showing excellent activity in the dismutation of superoxide radicals and negligible activity in other antioxidant tests. The structural characterization revealed that the advantageous coordination geometry around the copper (II) center contributed to the superior superoxide radical scavenging ability of the composite.
DALTON TRANSACTIONS
(2021)