Article
Environmental Sciences
Fatma Pinar Tabanli, Siddika Songuel Yalcin, Sedef Ramoglu, Sadiman Kiykac Altinbas, Anil Yirun, Aylin Balci Ozyurt, Funda Gucel, Pinar Erkekoglu, Kadriye Yurdakok
Summary: This study aimed to investigate the association between bisphenol A (BPA), 25-hydroxy vitamin D [25(OH)D], and 1 alpha,25 dihydroxy vitamin D [1,25( OH)(2)D] levels in cord blood of newborn babies. The results showed that both BPA exposure and insufficient vitamin D transfer via cord blood are common in newborns, but there is no correlation between BPA levels and vitamin D levels in cord blood.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Environmental Sciences
Fatma Pinar Tabanli, Siddika Songul Yalcin, Sedef Ramoglu, Sadiman Kiykac Altinbas, Anil Yirun, Aylin Balci ozyurt, Funda Gucel, Pinar Erkekoglu, Kadriye Yurdakok
Summary: This study investigated the association between BPA, 25(OH)D, and 1,25(OH)(2)D levels in cord blood of newborn babies. The study found that both BPA exposure and insufficient vitamin D transfer via cord blood are common in newborns, but BPA levels were not correlated with vitamin D levels in cord blood.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Review
Nutrition & Dietetics
Luis Castano, Leire Madariaga, Gema Grau, Alejandro Garcia-Castano
Summary: Vitamin D is crucial for bone mineralization in children and deficiency is common. Certain medical conditions and genetic alterations can increase the risk of vitamin D deficiency rickets. Measurement of calcifediol levels is used to assess the status of the vitamin D endocrine system. Clinical trials have demonstrated the benefits of ensuring normal 25(OH)D levels and calcium intake in preventing or treating nutritional rickets in children.
Article
Endocrinology & Metabolism
Haifa Maalmi, Christian Herder, Cornelia Huth, Wolfgang Rathmann, Gidon J. Boenhof, Margit Heier, Wolfgang Koenig, Michael Roden, Annette Peters, Dan Ziegler, Barbara Thorand
Summary: This study investigated the association between vitamin D and diabetic peripheral neuropathy (DSPN), with findings suggesting a link between lower serum vitamin D levels and higher prevalence of DSPN in individuals with obesity. However, the association between serum vitamin D levels and DSPN in the total study population of older individuals was not consistent.
INTERNATIONAL JOURNAL OF OBESITY
(2022)
Article
Nutrition & Dietetics
Hye Ran Shin, Hyeon Ju Park, Sun Yung Ly
Summary: Vitamin D deficiency is prevalent among young Korean women. This study aimed to determine the optimal vitamin D intake level for maintaining adequate serum 25-hydroxyvitamin D (25[OH]D) levels in young Korean women throughout different seasons. The study identified seasonal factors influencing 25(OH)D levels, calculated the necessary vitamin D intake for sufficient levels, and analyzed the relationship between 25(OH)D and intact parathyroid hormone (iPTH) levels. The results showed that 25(OH)D levels were higher in summertime compared to wintertime, and an increase in vitamin D intake led to a corresponding increase in 25(OH)D levels. The study suggests that increasing UV irradiation time in summertime and consuming vitamin D supplements and foods throughout the year is beneficial for maintaining sufficient levels of 25(OH)D in young Korean women.
Article
Nutrition & Dietetics
RuTong Wang, Weijing Wang, Ping Hu, Ronghui Zhang, Xue Dong, Dongfeng Zhang
Summary: This study aimed to evaluate the association between dietary vitamin D intake and serum vitamin D concentrations with cognitive performance in older Americans. The results showed a positive association between dietary vitamin D intake, serum total 25-hydroxyvitamin D, and cognitive performance, with no significant gender differences in the associations. Further research is needed to clarify the effects of dietary vitamin D intake and specific serum D concentrations on cognitive performance.
Article
Nutrition & Dietetics
Agnieszka Radom, Andrzej Wedrychowicz, Stanislaw Pieczarkowski, Szymon Skoczen, Przemyslaw Tomasik
Summary: Maintaining optimal vitamin D levels after breast cancer treatment is important for reducing recurrence risk and extending survival time. A study in Polish women after mastectomy found that vitamin D deficiency was more common in this group compared to the general population, highlighting the importance of vitamin D supplementation and monitoring. By providing recommendations and increasing awareness about vitamin D supplementation, there was a significant increase in the number of patients who started supplementing and the average dose of supplements.
Article
Nutrition & Dietetics
Chiara Tuma, Arne Schick, Nele Pommerening, Hans Braun, Mario Thevis
Summary: Vitamin D is crucial for athletes, and personalized supplementation is more effective than standardized supplementation in helping athletes achieve adequate vitamin D levels.
Article
Multidisciplinary Sciences
Hsin-Ya Tang, Wang-Sheng Ko, Yuan-Horng Yan, Su-Chen Yu, Ya-ling Chiou
Summary: Shift nurses in Taiwan often experience 25(OH)D deficiency, sleep disturbances, depression, and fatigue. However, no significant correlation was found between 25(OH)D levels and mental health.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Mehmet Emin Arayici, Sila Ovgu Korkut-Uysal, Asim Leblebici, Zeynep Akcali, Deniz Tuna Edizer, Seher Kabul, Dilek Cimrin, Ender Berat Ellidokuz
Summary: The aim of this study was to evaluate the change in 25-hydroxyvitamin D (25(OH)D) levels before and during the COVID-19 pandemic. The study found that restrictions, partial or complete closures, and curfews can significantly affect individuals' 25(OH)D levels during the COVID-19 outbreak. There is a need for multicenter studies with larger populations covering different regions to strengthen and support the results.
Article
Nutrition & Dietetics
Xiaoyun Shan, Xiayu Zhao, Siran Li, Pengkun Song, Qingqing Man, Zhen Liu, Yichun Hu, Lichen Yang
Summary: This study aims to analyze the associations between serum 25(OH)D levels and the risk of metabolic syndrome (MetS) and its components in non-diabetic women of childbearing age in China, considering both genetic and non-genetic factors. The findings suggest significant associations between insufficient serum 25(OH)D and components of MetS, including elevated waist circumference, triglycerides, and reduced high-density lipoprotein cholesterol. However, no independent associations were found between 25(OH)D levels and MetS, hypertension, and hyperglycemia.
Article
Biochemistry & Molecular Biology
Martyna Fronczek, Joanna Katarzyna Strzelczyk, Krzysztof Biernacki, Silvia Salatino, Tadeusz Osadnik, Zofia Ostrowska
Summary: The study investigated the role of genetic variation in the CYP2R1 gene in vitamin D deficiency among healthy Polish individuals. Two substitutions were found in selected gene fragments, with one potentially influencing the structure and function of CYP2R1. Further functional verification is needed to confirm these findings.
Article
Environmental Sciences
Elisabeth Thiering, Iana Markevych, Sara Kress, Thomas Astell-Burt, Xiaoqi Feng, Hicran Altug, Sibylle Koletzko, Carl-Peter Bauer, Andrea von Berg, Dietrich Berdel, Gunda Herberth, Tamara Schikowski, Joachim Heinrich, Marie Standl
Summary: There is a significant association between residential greenness and vitamin D levels in children and adolescents, and this association is also influenced by gene-environment interactions. The study found that the greenness of the living environment is associated with vitamin D levels, and this association is more pronounced in individuals with lower vitamin D levels.
ENVIRONMENTAL POLLUTION
(2023)
Article
Nutrition & Dietetics
Mehmet Emin Arayici, Yasemin Basbinar, Hulya Ellidokuz
Summary: This study used a meta-meta-analysis method to examine the effects of Vitamin D intake and serum 25-hydroxyvitamin-D levels on cancer incidence and mortality. The findings showed that higher Vitamin D intake and serum levels were associated with lower cancer risk and mortality. However, careful evaluation according to cancer types is important and recommended.
Article
Nutrition & Dietetics
Vid Vicic, Andreja Kukec, Sasa Kugler, Ksenija Gersak, Josko Osredkar, Ruza Pandel Mikus
Summary: The objective of this study was to evaluate vitamin D status and its predictors in Slovenian premenopausal and postmenopausal women. The study found that vitamin D insufficiency and deficiency were common among both premenopausal and postmenopausal women, with vitamin D supplementation and sun exposure being important predictors of vitamin D status. Interestingly, the vitamin D status in Slovenian postmenopausal women was better than in premenopausal women, which differs from similar studies.
Article
Transplantation
Xinting Cai, Barbara Thorand, Simon Hohenester, Wolfgang Koenig, Wolfgang Rathmann, Annette Peters, Jana Nano
Summary: This German cohort study aimed to evaluate the relationship between fatty liver and kidney function/chronic kidney disease (CKD). The study found that fatty liver is associated with kidney function and CKD, and this association is partially mediated by metabolic factors such as inflammation, diabetes, and hypertension.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2023)
Article
Environmental Sciences
Christian Herder, Siqi Zhang, Kathrin Wolf, Haifa Maalmi, Gidon J. Boenhof, Wolfgang Rathmann, Lars Schwettmann, Barbara Thorand, Michael Roden, Alexandra Schneider, Dan Ziegler, Annette Peters
Summary: This study used data from a population-based survey in Southern Germany to examine the association between environmental exposures and the risk of distal sensorimotor polyneuropathy (DSPN) in older individuals. The findings suggest that ubiquitous environmental factors, particularly in individuals with obesity, increase the risk of developing DSPN. Lower air temperature, reduced greenness, higher noise levels, and increased particle concentrations were associated with increased risk of DSPN, particularly in obese individuals.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Hasan Sohail, Virpi Kollanus, Pekka Tiittanen, Santtu Mikkonen, Anne H. Lipponen, Siqi Zhang, Susanne Breitner, Alexandra Schneider, Timo Lanki
Summary: This study investigated the associations between daily wintertime temperature and cold spells with cardiorespiratory hospital admissions in Helsinki, Finland. The results showed that decreased winter temperature was associated with an increased risk of hospitalization for myocardial infarction in the whole population. Additionally, there was an increased risk of hospital admission for respiratory diseases and chronic obstructive pulmonary disease in the age group of >= 75 years. Furthermore, cold spell days were found to have an independent effect on asthma admissions in all age groups.
AIR QUALITY ATMOSPHERE AND HEALTH
(2023)
Article
Critical Care Medicine
Elke Maurer, Roberto Lorbeer, Gerald Hefferman, Christopher L. Schlett, Annette Peters, Susanne Rospleszcz, Lena S. Kiefer, Konstantin Nikolaou, Fabian Bamberg, Sven S. Walter
Summary: This study aimed to assess the correlation between spinopelvic parameters and hip osteoarthritis (HOA), lateral center edge angle, and patient reported back pain. The results showed that there was no significant correlation between spinopelvic parameters and HOA or lateral center edge angle.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Sergios Gatidis, Turkay Kart, Marc Fischer, Stefan Winzeck, Ben Glocker, Wenjia Bai, Robin Buelow, Carina Emmel, Lena Friedrich, Hans-Ulrich Kauczor, Thomas Keil, Thomas Kroencke, Philipp Mayer, Thoralf Niendorf, Annette Peters, Tobias Pischon, Benedikt M. Schaarschmidt, Boerge Schmidt, Matthias B. Schulze, Lale Umutle, Henry Voelzke, Thomas Kuestner, Fabian Bamberg, Bernhard Schoelkopf, Daniel Rueckert
Summary: This study demonstrates how MRI data from the UK Biobank (UKBB) and German National Cohort (NAKO) can be jointly analyzed to derive comprehensive quantitative image-based phenotypes across the general adult population. The researchers extracted image-derived features of abdominal organs from T1-weighted Dixon MRI data and used causal discovery and batch effect correction methods to harmonize data from UKBB and NAKO. They performed quantile regression on the harmonized data, providing quantitative models for the variation of image-derived features stratified by sex and dependent on age, height, and weight.
INVESTIGATIVE RADIOLOGY
(2023)
Article
Meteorology & Atmospheric Sciences
Boyan H. Petkov, Vito Vitale, Piero Di Carlo, Oxana Drofa, Daniele Mastrangelo, Andrew R. D. Smedley, Henri Diemoz, Anna Maria Siani, Ilias Fountoulakis, Ann R. Webb, Alkiviadis Bais, Richard Kift, John Rimmer, Giuseppe Rocco Casale, Georg H. Hansen, Tove Svendby, Andrea Pazmino, Rolf Werner, Atanas M. Atanassov, Kamil Laska, Hugo De Backer, Alexander Mangold, Ulf Koehler, Voltaire A. Velazco, Rene Stuebi, Anna Solomatnikova, Kseniya Pavlova, Piotr S. Sobolewski, Bjorn Johnsen, Florence Goutail, Oliver Misaga, Eleonora Aruffo, Ladislav Metelka, Zoltan Toth, Denes Fekete, Alexandr A. Aculinin, Angelo Lupi, Mauro Mazzola, Federico Zardi
Summary: The response of Europe's ozone column to the extreme Arctic ozone depletion in 2020 was examined. Ground-based observations at 38 European stations showed a decrease in ozone concentration from north to south, with a maximum decrease of 43% at Ny-Ålesund (79°N) and a decrease of nearly 15% at 40°N. The ozone variations at different latitudes showed a delay of about 20 days compared to Ny-Ålesund. The spread of decreasing ozone from north to south was similar to the 2011 Arctic ozone depletion.
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES
(2023)
Article
Critical Care Medicine
Maximilian Schwarz, Alexandra Schneider, Josef Cyrys, Susanne Bastian, Susanne Breitner, Annette Peters
Summary: This study examined the association between short-term exposure to ultrafine particles (UFPs) and cause-specific mortality in three German cities. The risk of respiratory mortality increased within 1 week after exposure to UFPs, while no clear associations were found for cardiovascular or natural mortality. These findings provide evidence for the independent health effects of UFPs.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2023)
Article
Endocrinology & Metabolism
Hong Luo, Alina Bauer, Jana Nano, Agnese Petrera, Wolfgang Rathmann, Christian Herder, Stefanie M. Hauck, Benjamin B. Sun, Annika Hoyer, Annette Peters, Barbara Thorand
Summary: This study aimed to investigate the role of plasma proteins in glucose metabolism and type 2 diabetes development. The study identified several novel proteins associated with glucose metabolism abnormalities and type 2 diabetes, as well as confirming previously reported proteins. These findings highlight the importance of proteins in the pathogenesis of type 2 diabetes and suggest potential targets for diabetes treatment and prevention.
Article
Geriatrics & Gerontology
Thierno D. Diallo, Susanne Rospleszcz, Jana Fabian, Sven S. Walter, Elke Maurer, Corinna Storz, Frank Roemer, Wolfgang Rathmann, Annette Peters, Pia M. Jungmann, Matthias Jung, Fabian Bamberg, Lena S. Kiefer
Summary: This study evaluated the different associations of magnetic resonance imaging (MRI)-based paravertebral myosteatosis with lumbar disc degeneration in individuals with impaired glucose metabolism and normoglycaemic controls. The results showed a significant positive association between paravertebral myosteatosis and intervertebral disc degeneration in individuals with impaired glucose metabolism. No significant associations were found in the normoglycaemic controls. These findings emphasize the potential link between skeletal muscle and spinal-related diseases.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2023)
Article
Endocrinology & Metabolism
Min Fan, Anna-Janina Stephan, Karl Emmert-Fees, Annette Peters, Michael Laxy
Summary: This study aims to estimate the long-term health and economic consequences of improved risk factor control in German adults with type 2 diabetes. The results suggest that sustained improvements in glycemic, blood pressure, and lipid control can significantly improve patients' health and reduce healthcare expenditures.
Article
Environmental Sciences
Maximilian Schwarz, Alexandra Schneider, Josef Cyrys, Susanne Bastian, Susanne Breitner, Annette Peters
Summary: This study examined the short-term associations between ultrafine particles (UFP) and cause-specific hospital admissions in Leipzig, Dresden, and Augsburg, Germany. The results showed clear associations between PM2.5 and (cardio-)respiratory hospital admissions, while UFP and PNC did not show a clear association. Further multi-center studies are needed to draw definite conclusions on the health effects of UFP.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Environmental Sciences
Wenli Ni, Nikolaos Nikolaou, Cavin K. Ward-Caviness, Susanne Breitner, Kathrin Wolf, Siqi Zhang, Rory Wilson, Melanie Waldenberger, Annette Peters, Alexandra Schneider
Summary: Climate change poses a serious threat to human health worldwide, while aging populations increase. However, no study has ever investigated the effects of air temperature on epigenetic age acceleration. This study involved participants from two population-based studies in Germany and found that medium- and long-term exposures to high air temperature are associated with increases in epigenetic age acceleration. Overall, this study highlights the importance of considering climate change and temperature in relation to human health.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Environmental Sciences
Masna Rai, Susanne Breitner, Veronika Huber, Siqi Zhang, Annette Peters, Alexandra Schneider
Summary: This study examined the association between short-term exposure to air temperature and cause-specific cardiovascular and respiratory mortality in the 15 largest German cities over a 24-year period. The results showed that population susceptibility to cold and heat-related cardiovascular and respiratory mortality risk increased from 1993 to 2016.
ENVIRONMENTAL RESEARCH
(2023)
Article
Public, Environmental & Occupational Health
Augusto Di Castelnuovo, Marialaura Bonaccio, Simona Costanzo, Patrick McElduff, Allen Linneberg, Veikko Salomaa, Satu Mannisto, Jean Ferrieres, Jean Dallongeville, Barbara Thorand, Hermann Brenner, Marco Ferrario, Giovanni Veronesi, Abdonas Tamosiunas, Sameline Grimsgaard, Wojciech Drygas, Sofia Malyutina, Stefan Soederberg, Maria Nordendahl, Frank Kee, Guido Grassi, Salim Dabboura, Rossana Borchini, Dirk Westermann, Benedikt Schrage, Tanja Zeller, Kari Kuulasmaa, Stefan Blankenberg, Maria Benedetta Donati, Licia Iacoviello, Giovanni de Gaetano
Summary: This study investigated the association between socioeconomic status (SES) and alcohol-related diseases, and examined whether the relationship between moderate drinking and all-cause mortality is influenced by educational level (EL). The findings showed that moderate drinking was associated with a lower mortality rate in individuals with higher EL, while heavy drinking was associated with a higher mortality rate in those with lower EL. Therefore, recommendations to reduce alcohol intake should particularly target individuals with a low level of education.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Stefan Agewall, Susanne Breitner, Masna Rai, Massimo Stafoggia, Francesca De'Donato, Evangelia Samoli, Sofi A. Zafeiratou, Liliana Vazquez Fernandez, Shilpa Rao, Antonio Gasparrini, Pierre Masselot, Kristin Aunan, Alexandra Schneider, Siqi Zhang
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Girgis Obaid, Menitte Eroy, Jie Zhao, Shazia Bano, Mari Mino-Kenudson, Tayyaba Hasan
Summary: The presence of desmoplasia in pancreatic ductal adenocarcinoma (PDAC) is associated with poor treatment outcomes and reduced drug delivery. By analyzing collagen subtypes in PDAC tumors following different treatment regimens, immunofluorescence profiling can predict long-term survival and tumor growth inhibition. This information can aid in personalized treatment and improve patient survival.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Fatemeh Malekpour, Rashin Bahrami, Mahshid Hodjat, Neda Hakimiha, Behnam Bolhari, Aidin Sooratgar, Soheil Niavarzi
Summary: This study investigated the effect of photobiomodulation (PBM) therapy using an 808 nm diode laser on cellular modulation mechanisms in regenerative endodontic procedures (REPs). The results showed that PBM treatment significantly increased cell viability and migration, and enhanced the release of TGF-131 from dentin.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Pranathi Tata, Ramakrishnan Ganesan, Jayati Ray Dutta
Summary: Thin film coatings with potent antibacterial properties are widely used in medical devices, frequently touched surfaces, and food packaging. However, achieving antibacterial performance under both light and dark conditions remains a challenge. In this study, we successfully prepared AgBr-coated ZnO nanorod thin film architecture using a unique surfactant-mediated solution-phase spin-coating approach. The resulting structures showed dual functionality as antimicrobial agents and photosensitizers, effectively enhancing the visible-light photodisinfection efficacy of ZnO nanorods. The concentration of the surfactant-based precursor solution could be modulated to control the AgBr content. Additionally, components like urea and lactic acid were found to enhance the photocatalytic efficiency of the structures.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2024)