Article
Chemistry, Multidisciplinary
Sara Torabi, Mahdi Jamshidi, Sadegh Khazalpour, Hojjat Alizadeh
Summary: In this study, the one-pot electrochemical cyclization/nitration of (E)-3-(3,4-dihydroxyphenyl)acrylic acid (3,4-DHPA) and electronitration of two polyphenol derivatives (rutin and quercetin) were performed via intermolecular and normal Michael-type addition processes. The electrochemical behavior of the compounds and the Michael-type addition reaction were investigated using a divided cell and constant-current coulometry mode. The synthesized compounds were then evaluated for their antibacterial activity against different bacterial strains, and molecular docking was conducted to assess their interactions with receptors.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Agriculture, Dairy & Animal Science
Laura Haydee Vallejo Hernandez, Arni Xochitemol Hernandez, Epigmenio Castillo Gallegos, Manuel Gonzalez-Ronquillo, Einar Vargas-Bello-Perez, Luis Corona
Summary: This study found that supplementing crossbred F1 dairy cows fed on tropical grasses with 450 g/kg of concentrate does not have negative effects on milk yield and quality. Farmers can rely on tropical grasses and reduce feeding costs under these production conditions.
Article
Multidisciplinary Sciences
Tong Mu, Honghong Hu, Yanfen Ma, Huiyu Wen, Chaoyun Yang, Xiaofang Feng, Wan Wen, Juan Zhang, Yaling Gu
Summary: This study used WGCNA to analyze the mRNA expression profile data of bovine mammary epithelial cells and identified several modules and hub genes significantly associated with milk fat rate. The key candidate genes related to lipid metabolism were screened out, and PI4K2A showed the highest expression in the mammary gland and was enriched in GO terms and pathways related to milk fat metabolism. This study provides a theoretical basis for identifying potential pathways and hub genes involved in milk fat synthesis.
SCIENTIFIC REPORTS
(2022)
Article
Biochemistry & Molecular Biology
Liqiang Han, Qixue Huang, JingNa Yang, Wenyan Lu, Mingyue Hu, Yanbin Yang, Heshui Zhu, Kun Pang, Guoyu Yang
Summary: Milk fat in mammary epithelial cells is synthesized and secreted as lipid droplets in the form of milk fat globules (MFGs) covered by a lipid-protein membrane called the milk fat globule membrane (MFGM). This study investigated the effects of MFGM proteins from control and conjugated linoleic acid (CLA)-treated milk on lipid droplet formation in MAC-T cells. Results showed that CLA reduced milk fat content and MFG size parameters, while increasing the specific surface area (SSA). Proteomic analysis identified differentially expressed proteins in the CLA group, and CLA-MFGM proteins promoted lipid droplet fusion and influenced droplet size distribution in MAC-T cells.
Review
Biochemistry & Molecular Biology
Tessa M. van de Langerijt, James A. A. O'Mahony, Shane V. V. Crowley
Summary: Polyphenols have health benefits attributed to their antioxidant activity. Milk protein systems have been studied for their ability to bind and protect polyphenols, improving their bioavailability and bio-functional properties. This review compares different milk protein systems in terms of physicochemical properties, polyphenol binding performance, and enhancement of polyphenol functionality.
Article
Food Science & Technology
Neha Baliyan, Antim Kumar Maurya, Anil Kumar, Vijai Kant Agnihotri, Rakshak Kumar
Summary: This study isolated probiotic strains from raw cow milk of the Lahaul valley capable of producing cis-9, trans-11 CLA isomer, and exhibiting antioxidant and food formulation abilities. Genome sequencing revealed the presence of antibiotic-resistance and virulence genes in Enterococcus faecalis LJM:05. The strain Latilactobacillus curvatus LGM:16 was used to develop curdled milk with superior probiotic features, antioxidant activity, and CLA-producing ability.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Applied
Junjun Qing, Cheng Peng, Hongbing Chen, Haixing Li, Xiaohua Liu
Summary: The study aimed to investigate the impact of fermentation conditions on c9,t11-conjugated linoleic acid (CLA) synthesis by Lactobacillus casei, as well as its effects on whey syneresis, water holding capacity (WHC), and texture characteristics of set yogurt. The addition of 0.1% linoleic acid (LA) decreased whey syneresis by about 30%. UV-Vis absorption spectroscopy, 3D fluorescence spectroscopy, and CD spectroscopy revealed the interaction between LA and casein (CS), fi-lactoglobulin (fi-Lg), and bovine serum albumin (BSA). LA changed the microenvironment and polarity around amino acids, as well as the conformation of the three milk proteins. Scanning electron microscope (SEM) analysis showed that the addition of LA resulted in a more uniform and compact microstructure of the set yogurt, suggesting that LA can promote the crosslink of milk proteins, which may explain the reduction in whey syneresis.
Article
Biotechnology & Applied Microbiology
Maiko Nakashio, Eriko Ohgitani, Masaharu Shin-Ya, Masaya Kawamoto, Masaki Ichitani, Makoto Kobayashi, Takanobu Takihara, Hitoshi Kinugasa, Hiroyasu Ishikura, Osam Mazda
Summary: This study found that the addition of milk cancels the anti-SARS-CoV-2 effect of black tea, due to the binding of casein to galloylated theaflavins (gTFs) in the tea.
BIOENGINEERING-BASEL
(2023)
Article
Nanoscience & Nanotechnology
Timur A. Aliev, Vadim E. Belyaev, Anastasiya V. Pomytkina, Pavel V. Nesterov, Sergey Shityakov, Roman V. Sadovnichii, Alexander S. Novikov, Olga Yu. Orlova, Maria S. Masalovich, Ekaterina V. Skorb
Summary: The present study focuses on the electrochemical analysis of multicomponent mixtures, such as milk, and proposes a pattern recognition system for detecting antibiotic residues in skimmed milk using a combination of cyclic voltammetry and machine learning techniques. A multielectrode sensor was developed and experiments were conducted to understand the processes occurring at the electrode surface. The study also suggests the use of the gradient boosting algorithm for training the machine learning model, achieving high accuracy in recognizing antibiotics in milk.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Food Science & Technology
Bibiana Juan, Antonio-Jose Trujillo
Summary: This study investigated the acid and rennet milk coagulation properties of A2 milk compared to a control milk. The results showed differences between A2 milk and the control milk in acid gel density, latency time, rennet aggregation rate, and curd firmness, but no significant differences in acid and enzymatic coagulation times. The study suggests that acid and rennet coagulation dairy products can be manufactured from A2 milk without major differences compared to control milk.
Article
Chemistry, Applied
Mi Yan, Xue Shen, Shuning Zhong, Mengxue Diao, Changhui Zhao, Yanyang Xu, Tiehua Zhang
Summary: A system based on PDI-PBA was developed for sensitive detection and discrimination of tea polyphenols by utilizing dynamic borate ester bonds. The discrimination was achieved by analyzing the fluorescence quench ratios and the unique chemical structures of different tea polyphenols.
Article
Plant Sciences
Mei-Ya Liu, Dandan Tang, Yuanzhi Shi, Lifeng Ma, Qunfeng Zhang, Jianyun Ruan
Summary: Foliar nitrogen application during tea plant dormancy stage can significantly increase nitrogen concentration in mature leaves, improve the quality and yield of spring tea. Application of urea or liquid amino acid fertilizer twice during winter dormancy and twice during spring dormancy shows the best performance in reducing soil fertilization levels without compromising leaf nitrogen concentration or tea quality.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Chemistry, Applied
Davor Daniloski, Noel A. McCarthy, Inge Gazi, Todor Vasiljevic
Summary: This study investigated the effect of differences in beta-casein polymorphic structure on the acid-induced gelation behavior of corresponding skim milks. The results showed that skim milk containing A2/A2 beta-casein formed gels with lower elastic modulus, water holding capacity, and gel permeability compared to A1/A1 and A1/A2 gels. Microscopy images also revealed differences in gel structure, with A1/A1 and A1/A2 gels having a denser microstructure and smaller pore size. The composition of the milks, such as the amount of alpha-helixes, aggregated beta-sheets, calcium, and x-casein, may contribute to these differences in gelation.
FOOD HYDROCOLLOIDS
(2022)
Article
Green & Sustainable Science & Technology
Rulu Huang, Huai Liu, Junhua Zhang, Yuan Cheng, Liang He, Lincai Peng
Summary: This study presents a metal ion-polymer hybridization approach to design a Hf@PAN-TP nanofiber catalyst for the efficient conversion of LvA to GVL. The catalyst exhibited high activity, selectivity, and stability, highlighting its potential for biomass-derived aldehydes/ketones upgrading.
Article
Materials Science, Multidisciplinary
Di Chuan, Min Mu, Huan Hou, Na Zhao, Jinglun Li, Aiping Tong, Bingwen Zou, Haifeng Chen, Bo Han, Gang Guo
Summary: The study demonstrated that the DOX delivery system based on folic acid-functionalized EGCG showed promising results in targeting therapy for ovarian cancer. Enhanced cellular uptake, increased toxicity, and better tumor growth inhibition effect were observed compared to other groups, indicating potential applications in ovarian cancer therapy.
MATERIALS & DESIGN
(2021)
Article
Biochemistry & Molecular Biology
P. Bourassa, T. J. Thomas, J. Bariyanga, H. A. Tajmir-Riahi
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2015)
Article
Biochemistry & Molecular Biology
P. Bourassa, H. A. Tajmir-Riahi
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2015)
Article
Biochemistry & Molecular Biology
C. N. N'soukpoe-Kossi, P. Bourassa, J. S. Mandeville, L. Bekale, J. Bariyanga, H. A. Tajmir-Riahi
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2015)
Article
Biochemistry & Molecular Biology
C. N. N'soukpoe-Kossi, P. Bourassa, J. S. Mandeville, L. Bekale, H. A. Tajmir-Riahi
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2015)
Article
Biochemistry & Molecular Biology
P. Bourassa, P. Chanphai, H. A. Tajmir-Riahi
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2017)
Review
Biochemistry & Molecular Biology
D. Agudelo, P. Bourassa, G. Berube, H. A. Tajmir-Riahi
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2016)
Article
Materials Science, Paper & Wood
Philippe Bourassa, Jean Bouchard, Sylvain Robert
Article
Chemistry, Applied
P. Bourassa, C. N. N'soukpoe-Kossi, H. A. Tajmir-Riahi
Article
Biochemistry & Molecular Biology
P. Bourassa, L. Bekale, H. A. Tajmir-Riahi
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2014)
Article
Biochemistry & Molecular Biology
Daniel Agudelo, Philippe Bourassa, Gervais Berube, Heidar-Ali Tajmir-Riahi
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2014)
Article
Chemistry, Analytical
P. Bourassa, T. J. Thomas, H. A. Tajmir-Riahi
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2014)
Article
Chemistry, Analytical
C. N. N'soukpoe-Kossi, P. Bourassa, J. S. Mandeville, H. A. Tajmir-Riahi
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2014)
Article
Chemistry, Physical
P. Bourassa, J. Bariyanga, H. A. Tajmir-Riahi
JOURNAL OF PHYSICAL CHEMISTRY B
(2013)
Article
Multidisciplinary Sciences
Daniel Agudelo, Philippe Bourassa, Marc Beauregard, Gervais Berube, Heidar-Ali Tajmir-Riahi
Article
Biochemistry & Molecular Biology
Girgis Obaid, Menitte Eroy, Jie Zhao, Shazia Bano, Mari Mino-Kenudson, Tayyaba Hasan
Summary: The presence of desmoplasia in pancreatic ductal adenocarcinoma (PDAC) is associated with poor treatment outcomes and reduced drug delivery. By analyzing collagen subtypes in PDAC tumors following different treatment regimens, immunofluorescence profiling can predict long-term survival and tumor growth inhibition. This information can aid in personalized treatment and improve patient survival.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Fatemeh Malekpour, Rashin Bahrami, Mahshid Hodjat, Neda Hakimiha, Behnam Bolhari, Aidin Sooratgar, Soheil Niavarzi
Summary: This study investigated the effect of photobiomodulation (PBM) therapy using an 808 nm diode laser on cellular modulation mechanisms in regenerative endodontic procedures (REPs). The results showed that PBM treatment significantly increased cell viability and migration, and enhanced the release of TGF-131 from dentin.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Pranathi Tata, Ramakrishnan Ganesan, Jayati Ray Dutta
Summary: Thin film coatings with potent antibacterial properties are widely used in medical devices, frequently touched surfaces, and food packaging. However, achieving antibacterial performance under both light and dark conditions remains a challenge. In this study, we successfully prepared AgBr-coated ZnO nanorod thin film architecture using a unique surfactant-mediated solution-phase spin-coating approach. The resulting structures showed dual functionality as antimicrobial agents and photosensitizers, effectively enhancing the visible-light photodisinfection efficacy of ZnO nanorods. The concentration of the surfactant-based precursor solution could be modulated to control the AgBr content. Additionally, components like urea and lactic acid were found to enhance the photocatalytic efficiency of the structures.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2024)