Polymorphic Variants of Cytochrome P450 2B6 (CYP2B6.4-CYP2B6.9) Exhibit Altered Rates of Metabolism for Bupropion and Efavirenz: A Charge-Reversal Mutation in the K139E Variant (CYP2B6.8) Impairs Formation of a Functional Cytochrome P450-Reductase Complex

Published 2011 View Full Article

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Title
Polymorphic Variants of Cytochrome P450 2B6 (CYP2B6.4-CYP2B6.9) Exhibit Altered Rates of Metabolism for Bupropion and Efavirenz: A Charge-Reversal Mutation in the K139E Variant (CYP2B6.8) Impairs Formation of a Functional Cytochrome P450-Reductase Complex
Authors
Keywords
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Journal
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Volume 338, Issue 3, Pages 803-809
Publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)
Online
2011-06-10
DOI
10.1124/jpet.111.183111

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