Development of a Physiologically Based Pharmacokinetic Model for the Rat Central Nervous System and Determination of an In Vitro–In Vivo Scaling Methodology for the Blood–Brain Barrier Permeability of Two Transporter Substrates, Morphine and Oxycodone

Title
Development of a Physiologically Based Pharmacokinetic Model for the Rat Central Nervous System and Determination of an In Vitro–In Vivo Scaling Methodology for the Blood–Brain Barrier Permeability of Two Transporter Substrates, Morphine and Oxycodone
Authors
Keywords
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Journal
JOURNAL OF PHARMACEUTICAL SCIENCES
Volume 101, Issue 11, Pages 4277-4292
Publisher
Elsevier BV
Online
2012-08-04
DOI
10.1002/jps.23266

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