Journal
JOURNAL OF PERINATOLOGY
Volume 34, Issue 3, Pages 220-222Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/jp.2013.151
Keywords
human milk; preterm-born infants; bio-active proteins; total antioxidant capacity
Categories
Ask authors/readers for more resources
OBJECTIVE: As the antioxidant properties of human milk may be beneficial for very preterm-born infants, it is important to identify the association between total antioxidant capacity (TAC) and bio-active proteins. STUDY DESIGN: Breast milk was prospectively collected (four times) on postpartum days 6 to 8, 13 to 15, 20 to 22 and 27 to 29 from 15 mothers who had delivered between 24 and 31 weeks of gestation. Skimmed milk was assayed to measure TAC and bioactive proteins (lysozyme, lactoferrin, leptin and adiponectin). The association between TAC and levels of bio-active proteins during the first month of lactation was analyzed in a regression model. RESULT: Coefficient of determinations (R-2) revealed an overall effect of bio-active proteins on breast milk TAC (R-2 = 0.635+/- 0.102, P<0.0001). Breast milk leptin, lysozyme and lactoferrin levels were identified as independent factors that significantly predict the concentration of TAC. CONCLUSION: The identified enhancement of the antioxidant capacity of human milk by bio-active proteins that are lacking in commercial formula supports consideration of breast milk as ideal nutrition for preterm-born neonates.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available