Article
Obstetrics & Gynecology
F. Wuytack, R. Devlieger, L. Ameye, P. Corcoran, A. P. Fitzgerald, W. Ombelet, A. Bogaerts
Summary: Women with a higher BMI who use medically assisted reproduction (MAR) are at the highest risk of pregnancy and birth complications.
HUMAN REPRODUCTION
(2023)
Article
Medicine, General & Internal
Wontae Cha, Il Yun, Chung-Mo Nam, Jin Young Nam, Eun-Cheol Park
Summary: This study evaluates the impact of health insurance coverage for assisted reproductive technology (ART) on multiple pregnancies and births in Korea. The findings indicate that the implementation of the health insurance coverage policy has significantly increased the likelihood of multiple pregnancies and births in Korea, suggesting that the development and coverage of policies to support couples experiencing infertility may help address low fertility rates.
Article
Endocrinology & Metabolism
Julie M. Petersen, Jennifer A. Hutcheon, Lisa M. Bodnar, Samantha E. Parker, Katherine A. Ahrens, Martha M. Werler
Summary: This study investigated the relationship between gestational weight gain (GWG) and the size of infants at birth, and found that weight maintenance during the second and third trimesters may be associated with better birth weight for gestational age. However, it is unclear how this can be achieved (e.g., through diet and exercise interventions) due to the observational design of the study.
Article
Geosciences, Multidisciplinary
Dimitra Konsta, Jean-Louis Dufresne, Helene Chepfer, Jessica Vial, Tsuyoshi Koshiro, Hideaki Kawai, Alejandro Bodas-Salcedo, Romain Roehrig, Masahiro Watanabe, Tomoo Ogura
Summary: Several studies have shown that most climate models underestimate cloud cover and overestimate cloud reflectivity, particularly for the tropical low-level clouds. Through analyzing the characteristics of low-level tropical marine clouds simulated by six climate models, it is found that these models still exhibit a bias of too few and too bright clouds, and the reflectivity is particularly overestimated when cloud cover is low.
GEOPHYSICAL RESEARCH LETTERS
(2022)
Article
Public, Environmental & Occupational Health
Claire E. Margerison, Amber L. Pearson, Zihan Lin, Jonnell Sanciangco
Summary: The study found that changes in residential greenness were associated with preterm birth and birthweight. However, after controlling for time-invariant maternal characteristics, these associations were close to null. There was no relationship between greenness and birth outcomes among women who did not move but experienced changes in greenness within their residential location.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Obstetrics & Gynecology
Nefise Nazli Yenigul, Fedi Ercan, Hakan Sager, Elif Yuce Bilgin, Emin Ustunyurt
Summary: This study evaluated the role of uterocervical angle in predicting the duration of latent phase in postterm pregnancies. The results showed that uterocervical angle can significantly predict prolonged latent phase, and it has predictive value for the duration of labor in medically induced postterm pregnancies.
GINEKOLOGIA POLSKA
(2023)
Article
Obstetrics & Gynecology
Maren Goeckenjan, Daria Madej, Anna Klimova, Pauline Wimberger, Cahit Birdir, Katrin Glass
Summary: This study compared the maternal and neonatal risks of pregnancies following assisted reproductive treatment (ART) to spontaneously conceived pregnancies. The results showed that the overall maternofetal risks were higher after ART, with twin pregnancies being associated with more preterm deliveries and neonatal complications. The main influencing factor for maternal risks in ART pregnancies was found to be advanced maternal age, and actively avoiding twin pregnancies through single embryo transfer strategy can reduce risks.
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
(2021)
Article
Nutrition & Dietetics
Anna Dera-Szymanowska, Dorota Filipowicz, Natalia Misan, Krzysztof Szymanowski, Thilo Samson Chillon, Sabrina Asaad, Qian Sun, Ewelina Szczepanek-Parulska, Lutz Schomburg, Marek Ruchala
Summary: This study aims to compare iron and calcium levels in singleton and twin pregnancies, and found no significant differences between the two. Prenatal iron supplementation was shown to effectively increase iron levels.
Article
Developmental Biology
Amber Carroll, Michelle Desforges, Carolyn J. P. Jones, Alexander E. P. Heazell
Summary: Prolonged pregnancy is associated with reduced placental growth and functional changes, leading to increased risks of perinatal mortality, neonatal compromise, and birth by Caesarean section. These changes include reduced villous vascularity, oxidative stress, and cellular senescence, which are similar to fetal growth restriction and pre-eclampsia. Understanding the effects and risks of placental aging may guide clinicians in managing prolonged pregnancies.
Article
Health Care Sciences & Services
Louise Moniod, Agathe Hovine, Beatrice Trombert, Florence Rancon, Paul Zufferey, Laura Chauveau, Celine Chauleur, Tiphaine Raia-Barjat
Summary: This study aimed to assess the effects of providing maternal information about fetal movement counting on neonatal outcomes in prolonged pregnancy. The findings suggest that fetal movement counting during prolonged pregnancy did not significantly reduce adverse neonatal outcomes.
Article
Obstetrics & Gynecology
Vivienne Moore, Alice Rumbold, Renae Fernandez, Heather McElroy, Lynette Moore, Lynne Giles, Luke Grzeskowiak, Elizabeth Roughead, Michael Stark, Michael Davies
Summary: A study in South Australia found that 1.6% of pregnancies of at least 20 weeks' gestation were conceived with the use of clomiphene citrate (CC), with 5.7% resulting in multiple births. This increases the proportion of women who achieved an ongoing pregnancy with medical assistance from 4.4% to 6%.
FERTILITY AND STERILITY
(2022)
Article
Multidisciplinary Sciences
Hunter Brown, Xiaohong Liu, Rudra Pokhrel, Shane Murphy, Zheng Lu, Rawad Saleh, Tero Mielonen, Harri Kokkola, Tommi Bergman, Gunnar Myhre, Ragnhild B. Skeie, Duncan Watson-Paris, Philip Stier, Ben Johnson, Nicolas Bellouin, Michael Schulz, Ville Vakkari, Johan Paul Beukes, Pieter Gideon van Zyl, Shang Liu, Duli Chand
Summary: The study finds that current climate models overestimate the absorptivity of biomass burning aerosols, leading to inaccurate estimates of their direct radiative effects. By modifying the refractive index, size, and mixing state of the aerosols, the models can better match observations and improve accuracy in predicting aerosol effects on solar radiation.
NATURE COMMUNICATIONS
(2021)
News Item
Multidisciplinary Sciences
Heidi Ledford
Summary: This sentence points out that there are still technical obstacles while society is grappling with the social and ethical implications of heritable genome editing.
Article
Oncology
Eleonora Porcu, Linda Cipriani, Maria Dirodi, Pierandrea De Iaco, Anna Myriam Perrone, Pier Luigi Zinzani, Mario Taffurelli, Claudio Zamagni, Patrizia Maria Ciotti, Leonardo Notarangelo, Nilla Calza, Giuseppe Damiano
Summary: This study demonstrates that oocyte cryopreservation is a feasible and efficient option for fertility preservation in cancer patients, based on the comparison with nononcological patients undergoing in vitro fertilization treatments. The results show that cancer patients who undergo oocyte cryopreservation have a high pregnancy rate and birth rate, indicating the effectiveness of this method in preserving fertility.
Article
Pediatrics
Andrea Schmedding, Felix van Wasen, Ralf Lippert
Summary: An undescended testis is the most common genitourinary disease in boys. The study analyzed the implementation of German guidelines proposing orchidopexy before 12 months of age, 10 years after publication.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Letter
Dermatology
Marius Rademaker, Jose G. B. Derraik, Phil J. Sirvid
AUSTRALASIAN JOURNAL OF DERMATOLOGY
(2019)
Article
Endocrinology & Metabolism
Jose G. B. Derraik, Harriet L. Miles, Valentina Chiavaroli, Paul L. Hofman, Wayne S. Cutfield
CLINICAL ENDOCRINOLOGY
(2019)
Article
Public, Environmental & Occupational Health
J. G. B. Derraik, D. Pasupathy, L. M. E. McCowan, L. Poston, R. S. Taylor, N. A. B. Simpson, G. A. Dekker, J. Myers, M. C. Vieira, W. S. Cutfield, F. Ahlsson
JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE
(2019)
Article
Medicine, General & Internal
Yvonne C. Anderson, Kaye Kirkpatrick, Gerard M. S. Dolan, Trecia A. Wouldes, Cameron C. Grant, Tami L. Cave, Cervantee E. K. Wild, Jose G. B. Derraik, Wayne S. Cutfield, Paul L. Hofman
Review
Pediatrics
Valentina Chiavaroli, John D. Gibbins, Wayne S. Cutfield, Jose G. B. Derraik
WORLD JOURNAL OF PEDIATRICS
(2019)
Article
Nutrition & Dietetics
Marewa Glover, Sally F. Wong, Rachael W. Taylor, Jose G. B. Derraik, Jacinta Fa'alili-Fidow, Susan M. Morton, Wayne S. Cutfield
Article
Medicine, General & Internal
Karen S. W. Leong, Thilini N. Jayasinghe, Jose G. B. Derraik, Benjamin B. Albert, Valentina Chiavaroli, Darren M. Svirskis, Kathryn L. Beck, Cathryn A. Conlon, Yannan Jiang, William Schierding, Tommi Vatanen, David J. Holland, Justin M. O'Sullivan, Wayne S. Cutfield
Review
Pediatrics
Wayne Cutfield, Ahila Ayyavoo
Summary: 'Small for Gestational Age' (SGA) refers to children born with low birth weight and/or short birth length, most of whom experience catch-up growth within 6 months of age. Treatment with recombinant human growth hormone (rhGH) can help SGA children achieve normal adult height, although they may still face long-term consequences such as insulin resistance, abdominal fat accumulation, and metabolic disorders.
INDIAN JOURNAL OF PEDIATRICS
(2021)
Article
Endocrinology & Metabolism
Eda Cengiz, Thomas Danne, Tariq Ahmad, Ahila Ayyavoo, David Beran, Sarah Ehtisham, Jan Fairchild, Przemyslawa Jarosz-Chobot, Sze May Ng, Megan Paterson, Ethel Codner
PEDIATRIC DIABETES
(2022)
Article
Endocrinology & Metabolism
Sirisha Kusuma Boddu, Ahila Ayyavoo, Vani Hebbal Nagarajappa, Kiran Kalenahalli, Shantakumar Muruda, Raghupathy Palany
Summary: Prolonged hypothyroidism in children can cause short stature and delayed puberty, but a paradoxical occurrence of precocious puberty and pituitary enlargement in untreated juvenile hypothyroidism has been reported. This study aims to increase awareness and understanding of this clinical entity among healthcare professionals. Retrospective analysis of case records of children diagnosed with Van Wyk-Grumbach syndrome (VWGS) was conducted.
JOURNAL OF THE ENDOCRINE SOCIETY
(2023)
Review
Pediatrics
Ahila Ayyavoo
Summary: Enlargement of breasts among boys, known as gynecomastia, can be caused by changes in the androgen-estrogen ratio and the effects of various hormones. Factors such as puberty, obesity, drugs, and hypogonadism can contribute to gynecomastia. Other conditions including liver or renal failure, thyrotoxicosis, Klinefelter syndrome, tumors, and environmental pollutants can also cause gynecomastia. Medical management, including hormone therapy, is often effective in mild cases, while surgery may be necessary for severe and chronic gynecomastia.
INDIAN JOURNAL OF PEDIATRICS
(2023)
Article
Endocrinology & Metabolism
Priyanka Gangodkar, Vaman Khadilkar, P. Raghupathy, Rakesh Kumar, Archana Arya Dayal, Devi Dayal, Ahila Ayyavoo, Tushar Godbole, Rahul Jahagirdar, Kavitha Bhat, Neerja Gupta, Sadishkumar Kamalanathan, Sujatha Jagadeesh, Shatakshi Ranade, Nikhil Lohiya, Rashmi Lote Oke, Karthik Ganesan, Kavita Khatod, Meenal Agarwal, Nikhil Phadke, Anuradha Khadilkar
Summary: A comprehensive NGS-based assay was developed and validated for detecting variants in the CYP21A2 gene in Indian patients with 21-OH CAH. The study identified biallelic mutations in the majority of cases, with the most common mutations being c.293-13A/C>G and 30 kb deletion. Orthogonal confirmation showed 100% concordance with NGS results and nine novel variants were identified.
Article
Multidisciplinary Sciences
Sarah E. Maessen, Fredrik Ahlsson, Maria Lundgren, Wayne S. Cutfield, Jose G. B. Derraik
SCIENTIFIC REPORTS
(2019)
Article
Endocrinology & Metabolism
Ahila Ayyavoo, Palany Raghupathy, Meenal Agarwal, Paul Hofman
JOURNAL OF THE ENDOCRINE SOCIETY
(2018)
Review
Endocrinology & Metabolism
Karen S. W. Leong, Jose G. B. Derraik, Paul L. Hofman, Wayne S. Cutfield
CLINICAL ENDOCRINOLOGY
(2018)
Article
Pediatrics
Tarun Aurora, Audrey Cole, Parul Rai, Paul Lavoie, Carrie Mcivor, Lisa M. Klesges, Guolian Kang, Janaka S. S. Liyanage, Heather M. Brandt, Jane S. Hankins
Summary: This study evaluated the effectiveness of a vaccine strategy bundle in increasing HPV vaccine initiation and completion rates in a specialty clinic setting. By implementing the bundle, which included staff education, provider incentives, offering vaccines in clinics, and verifying vaccine completion, the clinic successfully improved HPV vaccine initiation and completion rates among sickle cell disease patients.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Nienke M. Halbmeijer, Wes Onland, Jeroen Dudink, Filip Cools, Anne Debeer, Anton H. van Kaam, Manon J. N. L. Benders, Niek E. van der Aa
Summary: In ventilated infants born preterm, high dose systemic hydrocortisone initiated between 7 and 14 days after birth did not have a significant impact on brain development.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Katherine Melton, Jianfang Liu, Hossein Sadeghi, Maureen George, Arlene Smaldone
Summary: This study aims to identify predictors of change in lung function and body weight during health care transition in cystic fibrosis (CF) patients. The study findings highlight the importance of CF RISE program engagement and reducing gaps in care for improving the transition of adolescents and young adults with CF.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Laura A. Duckworth, Kimberly A. Sutton, Nurmohammad Shaikh, Jinli Wang, Carla Hall-Moore, Lori R. Holtz, Phillip I. Tarr, Ronald C. Rubenstein
Summary: The study tested the usefulness of various biomarkers as indicators of gut dysfunction in cystic fibrosis (CF) and investigated the repeatability of these measures in individuals over short periods and their correlation with clinical outcomes. The results showed that elevated levels of fLcn2 in individuals with CF may predict worsened pulmonary function.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Lindsey Haack, Nikkan Das, Arvind Hoskoppal, Mark Debrunner, Tarek Alsaied, Gaurav Arora
Summary: RAE on ECG has a low positive predictive value for RAE on echocardiogram in previously healthy young patients. The highest yield for RAE on echocardiogram was observed in patients who were <1 year of age, had RAE in the anterior precordial leads, or displayed right ventricular hypertrophy on ECG.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Michael A. Padula, Khatija Naing, Tara L. Wenger, Irfan Ahmad, Carl H. Coghill, K. Taylor Wild, S. Alex Rottgers, Cory M. Resnick, Jeffrey Goldstein, Zarmina Ehsan, Donna Watkins, Nicole Deptula, Kuan-Chi Lai, Janet Lioy, Semsa Gogcu, Christopher M. Cielo
Summary: This study describes the spectrum of disease and burden of care in infants with congenital micrognathia. The results show that these infants commonly require surgical intervention and tube feedings, and disparities based on race and among centers were identified.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Michael P. Fundora, Manvitha Kalicheti, Guantao Zhao, Kevin O. Maher, Nicoleta Serban
Summary: This study investigated the variation of outpatient opioid prescribing in postoperative pediatric cardiac patients across the US. The results showed that there were significant differences in opioid prescribing by race, ethnicity, sex, and region.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Jia Guo, Brooklyn J. Fraser, Leigh Blizzard, Michael D. Schmidt, Terence Dwyer, Alison J. Venn, Costan G. Magnussen
Summary: There is a correlation between childhood and adulthood cardiorespiratory fitness.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Nianzhou Xiao, Michelle Starr, Adrienne Stolfi, Gilad Hamdani, Shireen Hashmat, Stefan G. Kiessling, Christina Sethna, Mahmoud Kallash, Robyn Matloff, Robert Woroniecki, Keia Sanderson, Ikuyo Yamaguchi, Stephen D. Cha, Michael G. Semanik, Rahul Chanchlani, Joseph T. Flynn, Mark Mitsnefes
Summary: This multicenter study reports that most infants diagnosed with idiopathic hypertension in the NICU will discontinue antihypertensive treatment within 2 years of discharge. Antenatal steroid treatment is associated with a decreased likelihood of needing antihypertensive therapy for more than 1 year.
JOURNAL OF PEDIATRICS
(2024)
Editorial Material
Pediatrics
Kanwaljit Singh, John Concato, Jonathan M. Davis
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Yaxing Meng, Harri Niinikoski, Suvi P. Rovio, Brooklyn J. Fraser, Feitong Wu, Antti Jula, Tapani Ronnemaa, Jorma S. A. Viikari, Olli T. Raitakari, Katja Pahkala, Costan G. Magnussen
Summary: This 26-year study shows a correlation between early-life non-HDL-C levels and future levels. Early dietary counseling can reduce the risk of high pediatric non-HDL-C, emphasizing the importance of early interventions in preventing cardiovascular risks.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Kelsey A. B. Gastineau, Rebecca Bell, Allison Hanes, Sandra Mckay, Eric Sigel, Filoteia Popescu, Evan C. Sommer, Shari Barkin
Summary: This study aimed to assess the self-reported counseling outcomes for a firearm safe storage counseling training program provided by the American Academy of Pediatrics. The results demonstrated significant improvement in counseling self-efficacy and frequency one month after the training.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Kathryn E. K. Berlin, William Scott, Sara Dawson, David Brousseau, Joanne M. Lagatta
Summary: This prospective cohort study aimed to investigate the impact of bronchopulmonary dysplasia (BPD) on the health-related quality of life (HRQL) of infants from NICU hospitalization to one year post-discharge. The study found that lower HRQL during NICU stay was associated with earlier gestational age, postnatal corticosteroid usage, outborn status, and gastrostomy tube placement. Lower HRQL at 3 and 12 months post-discharge was associated with readmissions, home oxygen use, parent-reported difficulty breathing, lower developmental scores, and not playing with other children. Most parents reported similar or improved HRQL after discharge, but parents of infants with respiratory symptoms experienced less improvement. Efforts to improve parent HRQL should focus on respiratory symptoms and social isolation.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Garett J. Griffith, Alan P. Wang, Robert I. Liem, Michael R. Carr, Tyler Corson, Kendra Ward
Summary: This study developed reference values for cardiorespiratory fitness in children aged 6-18 years without underlying heart disease, measured by peak oxygen uptake and treadmill time. Fitness levels increased with age in males but not females. Males generally exhibited higher fitness levels compared to females in the same age groups.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
David S. Liu, Patricia Miller, Anna Rothenberg, Carley Vuillermin, Peter M. Waters, Andrea S. Bauer
Summary: This study aims to determine if children with elbow flexion contracture (EFC) caused by brachial plexus birth injury (BPBI) are more likely to develop shoulder contracture and undergo surgical treatment. A retrospective review was conducted on children under 2 years old with BPBI who presented to a single children's hospital. The results showed that patients with EFC had reduced shoulder range of motion and higher odds of shoulder contracture and surgical treatment. Prompt referral to a BPBI specialty clinic is recommended for evaluation and potential surgery.
JOURNAL OF PEDIATRICS
(2024)
