4.6 Article

How Are Childhood Thyroid Nodules Discovered: Opportunities for Improving Early Detection

Journal

JOURNAL OF PEDIATRICS
Volume 164, Issue 3, Pages 658-660

Publisher

MOSBY-ELSEVIER
DOI: 10.1016/j.jpeds.2013.10.090

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Funding

  1. Harvard Catalyst, The Harvard Clinical and Translational Science Center [National Center for Research Resources]
  2. National Center for Advancing Translational Sciences, National Institutes of Health [8UL1TR000170-05]
  3. Harvard University and its affiliated academic health care centers

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In a retrospective analysis of childhood thyroid nodules, 18% were radiographic incidentalomas and 41% were discovered by a clinician's palpation; 40% were discovered by patients' families. The latter group had the largest nodules and highest rates of thyroid cancer metastasis, suggesting opportunities for earlier detection through annual well-child visits.

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