Article
Pediatrics
Christina L. Herrera, Priyanka S. Kadari, Jessica E. Pruszynski, Imran Mir
Summary: Maternal infection does not appear to be directly linked to neurodevelopmental impairment or death at 2 years of age in extremely preterm infants. However, acute histologic chorioamnionitis is associated with this outcome, suggesting the need for further research into the impact of infection and immune response on outcomes in extremely preterm infants.
PEDIATRIC RESEARCH
(2023)
Article
Clinical Neurology
Michele Luzzati, Caterina Coviello, Henriette Swarenburg De Veye, Jeroen Dudink, Femke Lammertink, Carlo Dani, Corine Koopmans, Manon Benders, Maria Luisa Tataranno
Summary: This study aimed to investigate the association between morphine exposure in the neonatal period and neurodevelopment at 2 and 5 years of age while controlling for potential confounders. The study found that morphine exposure in infants born preterm is associated with poorer Full-Scale IQ and Performance IQ at 5 years. Individualized morphine administration is advised in infants born extremely preterm.
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
(2023)
Article
Medicine, General & Internal
Harald Ehrhardt, Adrien M. Aubert, Ulrika Aden, Elizabeth S. Draper, Anna Gudmundsdottir, Heili Varendi, Tom Weber, Michael Zemlin, Rolf F. Maier, Jennifer Zeitlin
Summary: This study found no association between Apgar scores and long-term outcomes in infants born extremely preterm (EPT). This may be due to high interobserver variability in Apgar scoring, poorer response to resuscitation after birth among EPT infants, and the influence of more deleterious exposures in the neonatal intensive care unit or socioeconomic factors on outcomes during the first 5 years of life.
Article
Medicine, General & Internal
Mihai Puia-Dumitrescu, Thomas R. Wood, Bryan A. Comstock, Janessa B. Law, Kendell German, Krystle M. Perez, Semsa Gogcu, Dennis E. Mayock, Patrick J. Heagerty, Sandra E. Juul
Summary: This study aimed to describe the use of corticosteroids in extremely preterm infants and evaluate their association with neurodevelopmental outcomes. The results showed that long-duration and higher cumulative dose of dexamethasone were associated with worse neurodevelopmental scores at 2 years of age.
Article
Medicine, General & Internal
Mihai Puia-Dumitrescu, Bryan A. Comstock, Sijia Li, Patrick J. Heagerty, Krystle M. Perez, Janessa B. Law, Thomas R. Wood, Semsa Gogcu, Dennis E. Mayock, Sandra E. Juul
Summary: This study investigated the use of opioids and benzodiazepines in extremely preterm infants during neonatal intensive care unit hospitalization, and found that prolonged combined use of these drugs was associated with poorer neurodevelopmental outcomes.
Article
Obstetrics & Gynecology
Matthew A. Rysavy, Tarah T. Colaizy, Carla M. Bann, Sara B. DeMauro, Andrea F. Duncan, Jane E. Brumbaugh, Myriam Peralta-Carcelen, Heidi M. Harmon, Karen J. Johnson, Susan R. Hintz, Betty R. Vohr, Edward F. Bell
Summary: This study aimed to investigate the relationship between neurodevelopmental impairment (NDI) and concurrent outcomes for extremely preterm children at 18-22 months' corrected age. The severity of NDI was found to be associated with rehospitalization, respiratory medications, surgery, and medical support services, but a significant percentage of children without NDI were also affected. These findings emphasize the importance of considering NDI in counseling families and designing studies for childhood outcomes.
JOURNAL OF PERINATOLOGY
(2021)
Article
Pediatrics
Janessa B. Law, Thomas R. Wood, Semsa Gogcu, Bryan A. Comstock, Manjiri Dighe, Krystle Perez, Mihai Puia-Dumitrescu, Dennis E. Mayock, Patrick J. Heagerty, Sandra E. Juul
Summary: The study aimed to determine the incidence, timing, progression, and risk factors of intracranial hemorrhage (ICH) in extremely preterm infants, as well as its association with death or neurodevelopmental impairment (NDI) at 2 years of corrected age. Risk factors for ICH varied by timing of bleed, and bilateral or increasing grade of ICH were associated with adverse outcomes in infants born extremely preterm.
JOURNAL OF PEDIATRICS
(2021)
Article
Pediatrics
Mercedes Bell, Conrad R. Cole, Nellie Hansen, Andrea F. Duncan, Susan R. Hintz, Ira Adams-Chapman
Summary: The study revealed that preterm infants with SBS had worse neurodevelopmental and growth outcomes compared to those without SBS, indicating an increased risk of moderate-severe neurodevelopmental impairment.
JOURNAL OF PEDIATRICS
(2021)
Article
Nutrition & Dietetics
Yung-Chieh Lin, Chi-Hsiang Chu, Yen-Ju Chen, Ray-Bing Chen, Chao-Ching Huang
Summary: Feeding progression patterns in extremely preterm infants in the first eight weeks are associated with head-circumference growth and neurodevelopmental outcomes. Slow progression group showed slower growth, higher rates of microcephaly and neurodevelopmental impairment at 24 months.
Article
Medicine, General & Internal
Mathias L. Hansen, Adelina Pellicer, Simon Hyttel-Srensen, Ebru Ergenekon, Tomasz Szczapa, Cornelia Hagmann, Gunnar Naulaers, Jonathan Mintzer, Monica Fumagalli, Gabriel Dimitriou, Eugene Dempsey, Jakub Tkaczyk, Guoqiang Cheng, Siv Fredly, Anne M. Heuchan, Gerhard Pichler, Hans Fuchs, Saudamini Nesargi, Gitte H. Hahn, Salvador Piris-Borregas, Jan Sirc, Miguel Alsina-Casanova, Martin Stocker, Hilal Ozkan, Kosmas Sarafidis, Andrew O. Hopper, Tanja Karen, Beata Rzepecka-Weglarz, Serife S. Oguz, Luis Arruza, Asli C. Memisoglu, Ruth del Rio Florentino, Mariana Baserga, Pierre Maton, Anita C. Truttmann, Isabel de las Cuevas, Peter Agergaard, Pamela Zafra, Lars Bender, Ryszard Lauterbach, Chantal Lecart, Julie de Buyst, Afif El-Khuffash, Anna Curley, Olalla O. Vaccarello, Jan Miletin, Evangelia Papathoma, Zachary Vesoulis, Giovanni Vento, Luc Cornette, Laura S. Lopez, Beril Yasa, Anja Klamer, Massimo Agosti, Olivier Baud, Emmanuele Mastretta, Merih Cetinkaya, Karen McCall, Shujuan Zeng, Eleftheria Hatzidaki, Agata Bargiel, Sylwia Marciniak, Xiaoyan Gao, Lin Huijia, Lina Chalak, Ling Yang, Shashidhar A. Rao, Xin Xu, Begona L. Gonzalez, Maria Wilinska, Zhaoqing Yin, Iwona Sadowska-Krawczenko, Itziar Serrano-Vinuales, Barbara Krolak-Olejnik, Marta M. Ybarra, Catalina Morales-Betancourt, Peter Korcek, Marta Teresa-Palacio, Fabio Mosca, Anja Hergenhan, Nilgun Koksal, Konstantia Tsoni, Munaf M. Kadri, Claudia Knoepfli, Elzbieta Rafinska-Wazny, Mustafa S. Akin, Tone Nordvik, Zhang Peng, Sinem G. Kersin, Liesbeth Thewissen, Ana Alarcon, David Healy, Berndt Urlesberger, Muenevver Bas, Jana Baumgartner, Eleni Skylogianni, Veronika Karadyova, Eva Valverde, Elena Bergon-Sendin, Jachym Kucera, Silvia Pisoni, Le Wang, Anne Smits, Rebeca Sanchez-Salmador, Marie I. Rasmussen, Markus H. Olsen, Aksel K. Jensen, Christian Gluud, Janus C. Jakobsen, Gorm Greisen
Summary: A multicenter, randomized trial found that treatment guided by cerebral oximetry monitoring for the first 72 hours after birth did not reduce the risk of death or severe brain injury at 36 weeks' postmenstrual age in extremely preterm infants.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Pediatrics
Debra E. Weese-Mayer, Juliann M. Di Fiore, Douglas E. Lake, Anna Maria Hibbs, Nelson Claure, Jiaxing Qiu, Namasivayam Ambalavanan, Eduardo Bancalari, James S. Kemp, Amanda M. Zimmet, John L. Carroll, Richard J. Martin, Katy N. Krahn, Aaron Hamvas, Sarah J. Ratcliffe, Narayanan Krishnamurthi, Premananda Indic, Alaleh Dormishian, Phyllis A. Dennery, J. Randall Moorman
Summary: The study found that cardioventilatory events peak during the first month of life in extremely preterm infants, but the trajectory afterwards depends on the type of event, race, sex, and use of mechanical ventilation. Apnea, periodic breathing, and intermittent hypoxemia events rose from day 3 of life then fell to near-resolution by 8-12 weeks of age. Apnea and intermittent hypoxemia were inversely correlated with gestational age, while periodic breathing was positively correlated with gestational age.
PEDIATRIC RESEARCH
(2023)
Article
Pediatrics
Itay Zamir, Elisabeth Stoltz Sjostrom, Fredrik Ahlsson, Ingrid Hansen-Pupp, Fredrik Serenius, Magnus Domellof
Summary: The study found that neonatal hyperglycaemia was associated with lower intelligence and motor outcomes at 6.5 years of age, with longer durations of hyperglycaemia linked to worse results. However, insulin treatment was not associated with any neurodevelopmental outcomes in extremely preterm infants.
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION
(2021)
Article
Obstetrics & Gynecology
Shie Rinat, Margot Mackay, Anne Synnes, Liisa Holsti, Jill G. Zwicker
Summary: The study found that early feeding behaviors significantly predicted motor outcomes at 4-5 years old. Extremely preterm infants with early feeding difficulties should be identified as at high risk for poor motor outcomes later in childhood and screened for early diagnosis and intervention.
EARLY HUMAN DEVELOPMENT
(2022)
Article
Medicine, General & Internal
Ngiik-Ping Tiong, Chun-Chih Peng, Mary Hsin-Ju Ko, Kai-Ti Tseng, Jui-Hsing Chang, Chyong-Hsin Hsu, Yi-Hsiang Sung, Hung-Yang Chang
Summary: The long-term exposure to inhaled corticosteroids (ICS) did not have a significant impact on neurodevelopment in extremely low birth weight preterm infants who were dependent on ventilators, but it did not reduce the duration of their dependence on oxygen and mechanical ventilation.
JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
(2021)
Review
Pediatrics
Silvia Guiducci, Leonardo Meggiolaro, Anna Righetto, Marco Piccoli, Eugenio Baraldi, Alfonso Galderisi
Summary: Glucose impairment is common in preterm infants, but the impact of early neonatal hyperglycemia on long-term neurodevelopment is still controversial. This review examines current evidence and finds an association between hyperglycemia and neurological delay in the first two years of life, especially for motor functions.
Review
Pediatrics
Lucinda J. Weaver, Colm P. Travers, Namasivayam Ambalavanan, David Askenazi
Summary: This article discusses the impact of excessive fluid accumulation on neonates and its related pathophysiology, and provides clinical recommendations for monitoring, prevention, and treatment of fluid overload.
PEDIATRIC NEPHROLOGY
(2023)
Article
Pediatrics
Jeremy M. Loberger, Ryan M. Jones, Adeline S. Phillips, Jeremy A. Ruhlmann, A. K. M. Fazlur Rahman, Namasivayam Ambalavanan, Priya Prabhakaran
Summary: This study aimed to evaluate the relationship between endotracheal secretions and pediatric extubation failure, and found that the evaluation of secretion character by bedside nurses was independently associated with extubation failure. A model combining other key factors showed good discrimination for predicting extubation outcomes.
PEDIATRIC RESEARCH
(2023)
Article
Pediatrics
Carla M. Bann, Jamie E. Newman, Brenda Poindexter, Katherine Okoniewski, Sara DeMauro, Scott A. Lorch, Deanne Wilson-Costello, Namasivayam Ambalavanan, Myriam Peralta-Carcelen, Catherine Limperopoulos, Kushal Kapse, Jonathan M. Davis, Michele Walsh, Stephanie Merhar
Summary: This study aims to investigate the effects of maternal opioid use during pregnancy on fetal and early infant development, and provide insights through MRI and comprehensive neurodevelopmental assessments. By conducting serial MRI assessments and umbilical cord assays, the study offers detailed understanding of brain development in this high-risk population.
PEDIATRIC RESEARCH
(2023)
Article
Critical Care Medicine
Samuel J. Gentle, Colm P. Travers, Matthew Clark, Waldemar A. Carlo, Namasivayam Ambalavanan
Summary: In extremely preterm infants on respiratory support on postnatal day 28, the presence and longer duration of patent ductus arteriosus (PDA) were associated with the development of bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH).
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2023)
Article
Critical Care Medicine
Samuel J. Gentle, Colm P. Travers, Arie Nakhmani, Premananda Indic, Waldemar A. Carlo, Namasivayam Ambalavanan
Summary: Early identification of infants with bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH) is crucial due to the higher risk of death. We investigated the intermittent hypoxemia (IH) patterns in infants with BPD-PH and compared them with infants with BPD alone. Our findings showed that infants with BPD-PH had longer duration of hypoxemic events, which was associated with both the diagnosis of BPD-PH and death in these infants.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2023)
Article
Engineering, Biomedical
Pravinkumar G. Kandhare, Namasivayam Ambalavanan, Colm P. Travers, Waldemar A. Carlo, Nikolay M. Sirakov, Arie Nakhmani
Summary: Prediction of biomedical signal changes is useful for clinical applications, but evaluation and applicability of prediction tools depend on specific clinical contexts. This study proposes a novel method to evaluate and compare vital sign predictors and validates it for rare events scenarios. Experimental results show that simple statistical predictors can outperform state-of-the-art deep learning architectures for low-dimensional signals.
BIOMEDICAL SIGNAL PROCESSING AND CONTROL
(2023)
Article
Critical Care Medicine
Namasivayam Ambalavanan, Debra E. Weese-Mayer, Anna Maria Hibbs, Nelson Claure, John L. Carroll, J. Randall Moorman, Eduardo Bancalari, Aaron Hamvas, Richard J. Martin, Juliann M. Di Fiore, Premananda Indic, James S. Kemp, Alaleh Dormishian, Katy N. Krahn, Jiaxing Qiu, Phyllis A. Dennery, Sarah J. Ratcliffe, James F. Troendle, Douglas E. Lake
Summary: Immature control of breathing in extremely preterm infants is associated with apnea, periodic breathing, intermittent hypoxemia, and bradycardia. Analyzing cardiorespiratory monitoring data can predict unfavorable respiratory outcomes at 40 weeks postmenstrual age and other outcomes such as bronchopulmonary dysplasia at 36 weeks postmenstrual age.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2023)
Article
Pediatrics
Colm P. Travers, Waldemar A. Carlo, Arie Nakhmani, Deborah Laney, Rouba A. Chahine, Immaculada Aban, Namasivayam Ambalavanan
Summary: This single-center trial aimed to determine if targeting higher levels of transcutaneous carbon dioxide improves respiratory stability among very preterm infants on ventilatory support. The results showed that adjusting the levels of transcutaneous carbon dioxide did not improve respiratory stability, and achieving and maintaining the intended carbon dioxide separation was difficult.
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION
(2023)
Article
Pediatrics
Jane E. Brumbaugh, Betty R. Vohr, Edward F. Bell, Carla M. Bann, Colm P. Travers, Elisabeth C. Mcgowan, Heidi M. Harmon, Waldemar A. Carlo, Andrea F. Duncan, Susan R. Hintz
Summary: This study aims to analyze the relationship between social determinants of health (SDOH) and outcomes for extremely preterm infants. The results showed that infants born to mothers with public/no insurance had older postmenstrual age (PMA) at discharge and were more likely to be readmitted. Children exposed to multiple risk-associated SDOH at birth had higher rates of neurodevelopmental impairment (NDI) and death postdischarge compared to those not exposed.
JOURNAL OF PEDIATRICS
(2023)
Article
Pediatrics
Vivek V. Shukla, A. K. M. Fazlur Rahman, Xuejun Shen, Allison Black, Nitin Arora, C. Vivek Lal, Edward F. Bell, Arie Nakhmani, Chengcui Zhang, Namasivayam Ambalavanan, Waldemar A. Carlo
Summary: The study evaluated the association between the COVID-19 pandemic and stillbirth and neonatal mortality rates. The findings showed that the neonatal mortality rate decreased during the pandemic periods compared to the baseline period, while the stillbirth rate did not significantly change.
PEDIATRIC RESEARCH
(2023)
Article
Pediatrics
Pravitha Ramanand, Premananda Indic, Colm P. Travers, Namasivayam Ambalavanan
Summary: This study aimed to investigate oxygenation patterns during two types of oxygen supplementation in preterm infants and assess their performance in hypoxemia risk screening during NICU monitoring. The findings showed that oxygen saturation had higher volatility and complexity during digitally-set servo-controlled oxygen environment supplementation. Additionally, variability measures of oxygen saturation exhibited early prognostic value in discriminating infants at higher risk of hypoxemic events. Multivariate models with two features showed good performance in risk stratification.
FRONTIERS IN PEDIATRICS
(2023)
Article
Obstetrics & Gynecology
Charles E. Green, Jon E. Tyson, Roy J. Heyne, Susan R. Hintz, Betty R. Vohr, Carla M. Bann, Abhik Das, Edward F. Bell, Sana Boral Debsareea, Emily Stephens, Marie G. Gantz, Carolyn M. Petrie Huitema, Karen J. Johnson, Kristi L. Watterberg, Ricardo Mosquera, Myriam Peralta-Carcelen, Deanne E. Wilson-Costello, Tarah T. Colaizy, Nathalie L. Maitre, Stephanie L. Merhar, Ira Adams-Chapman, Janell Fuller, Michelle E. Hartley-McAndrew, William F. Malcolm, Sarah Winter, Andrea F. Duncan, Gary J. Myer, Stephen D. Kicklighter, Myra H. Wyckoff, Sara B. DeMauro, Anna Maria Hibbs, Barbara J. Stoll, Waldemar A. Carlo, Krisa P. Van Meurs, Matthew A. Rysavy, Ravi M. Patel, Pablo J. Sanchez, Abbot R. Laptook, C. Michael Cotten, Carl T. D'Angio, Michele C. Walsh
Summary: The use of Bayley III norm-based thresholds may underestimate the impairment rates of extremely preterm infants. Assessing these rates relative to healthy term infants born in the same hospital may be a better approach.
JOURNAL OF PERINATOLOGY
(2023)
Article
Pediatrics
Debra E. Weese-Mayer, Juliann M. Di Fiore, Douglas E. Lake, Anna Maria Hibbs, Nelson Claure, Jiaxing Qiu, Namasivayam Ambalavanan, Eduardo Bancalari, James S. Kemp, Amanda M. Zimmet, John L. Carroll, Richard J. Martin, Katy N. Krahn, Aaron Hamvas, Sarah J. Ratcliffe, Narayanan Krishnamurthi, Premananda Indic, Alaleh Dormishian, Phyllis A. Dennery, J. Randall Moorman
Summary: The study found that cardioventilatory events peak during the first month of life in extremely preterm infants, but the trajectory afterwards depends on the type of event, race, sex, and use of mechanical ventilation. Apnea, periodic breathing, and intermittent hypoxemia events rose from day 3 of life then fell to near-resolution by 8-12 weeks of age. Apnea and intermittent hypoxemia were inversely correlated with gestational age, while periodic breathing was positively correlated with gestational age.
PEDIATRIC RESEARCH
(2023)
Article
Microbiology
Ahmed Abdelgawad, Teodora Nicola, Isaac Martin, Brian A. Halloran, Kosuke Tanaka, Comfort Y. Adegboye, Pankaj Jain, Changchun Ren, Charitharth V. Lal, Namasivayam Ambalavanan, Amy E. O'Connell, Tamas Jilling, Kent A. Willis
Summary: This study identifies a gut-lung axis driven by intestinal AMP expression and mediated by the intestinal microbiota that is linked to lung injury in newborns. These findings support that intestinal AMPs modulate lung injury and repair.
Article
Psychiatry
Carla M. Bann, Katherine C. Okoniewski, Leslie Clarke, Deanne Wilson-Costello, Stephanie Merhar, Sara DeMauro, Scott Lorch, Namasivayam Ambalavanan, Myriam Peralta-Carcelen, Catherine Limperopoulos, Brenda Poindexter, Jonathan M. Davis, Michele Walsh, Jamie Newman
Summary: This study found that perceived stigma in healthcare settings during pregnancy is associated with psychological distress in the postpartum period. Individuals who reported stigma had higher levels of depression, anxiety, and anger, and lower levels of well-being. They were also more likely to experience food insecurity, adverse childhood experiences, and abuse during pregnancy, and had less emotional support.
ARCHIVES OF WOMENS MENTAL HEALTH
(2023)
Article
Pediatrics
Tarun Aurora, Audrey Cole, Parul Rai, Paul Lavoie, Carrie Mcivor, Lisa M. Klesges, Guolian Kang, Janaka S. S. Liyanage, Heather M. Brandt, Jane S. Hankins
Summary: This study evaluated the effectiveness of a vaccine strategy bundle in increasing HPV vaccine initiation and completion rates in a specialty clinic setting. By implementing the bundle, which included staff education, provider incentives, offering vaccines in clinics, and verifying vaccine completion, the clinic successfully improved HPV vaccine initiation and completion rates among sickle cell disease patients.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Nienke M. Halbmeijer, Wes Onland, Jeroen Dudink, Filip Cools, Anne Debeer, Anton H. van Kaam, Manon J. N. L. Benders, Niek E. van der Aa
Summary: In ventilated infants born preterm, high dose systemic hydrocortisone initiated between 7 and 14 days after birth did not have a significant impact on brain development.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Katherine Melton, Jianfang Liu, Hossein Sadeghi, Maureen George, Arlene Smaldone
Summary: This study aims to identify predictors of change in lung function and body weight during health care transition in cystic fibrosis (CF) patients. The study findings highlight the importance of CF RISE program engagement and reducing gaps in care for improving the transition of adolescents and young adults with CF.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Laura A. Duckworth, Kimberly A. Sutton, Nurmohammad Shaikh, Jinli Wang, Carla Hall-Moore, Lori R. Holtz, Phillip I. Tarr, Ronald C. Rubenstein
Summary: The study tested the usefulness of various biomarkers as indicators of gut dysfunction in cystic fibrosis (CF) and investigated the repeatability of these measures in individuals over short periods and their correlation with clinical outcomes. The results showed that elevated levels of fLcn2 in individuals with CF may predict worsened pulmonary function.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Lindsey Haack, Nikkan Das, Arvind Hoskoppal, Mark Debrunner, Tarek Alsaied, Gaurav Arora
Summary: RAE on ECG has a low positive predictive value for RAE on echocardiogram in previously healthy young patients. The highest yield for RAE on echocardiogram was observed in patients who were <1 year of age, had RAE in the anterior precordial leads, or displayed right ventricular hypertrophy on ECG.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Michael A. Padula, Khatija Naing, Tara L. Wenger, Irfan Ahmad, Carl H. Coghill, K. Taylor Wild, S. Alex Rottgers, Cory M. Resnick, Jeffrey Goldstein, Zarmina Ehsan, Donna Watkins, Nicole Deptula, Kuan-Chi Lai, Janet Lioy, Semsa Gogcu, Christopher M. Cielo
Summary: This study describes the spectrum of disease and burden of care in infants with congenital micrognathia. The results show that these infants commonly require surgical intervention and tube feedings, and disparities based on race and among centers were identified.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Michael P. Fundora, Manvitha Kalicheti, Guantao Zhao, Kevin O. Maher, Nicoleta Serban
Summary: This study investigated the variation of outpatient opioid prescribing in postoperative pediatric cardiac patients across the US. The results showed that there were significant differences in opioid prescribing by race, ethnicity, sex, and region.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Jia Guo, Brooklyn J. Fraser, Leigh Blizzard, Michael D. Schmidt, Terence Dwyer, Alison J. Venn, Costan G. Magnussen
Summary: There is a correlation between childhood and adulthood cardiorespiratory fitness.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Nianzhou Xiao, Michelle Starr, Adrienne Stolfi, Gilad Hamdani, Shireen Hashmat, Stefan G. Kiessling, Christina Sethna, Mahmoud Kallash, Robyn Matloff, Robert Woroniecki, Keia Sanderson, Ikuyo Yamaguchi, Stephen D. Cha, Michael G. Semanik, Rahul Chanchlani, Joseph T. Flynn, Mark Mitsnefes
Summary: This multicenter study reports that most infants diagnosed with idiopathic hypertension in the NICU will discontinue antihypertensive treatment within 2 years of discharge. Antenatal steroid treatment is associated with a decreased likelihood of needing antihypertensive therapy for more than 1 year.
JOURNAL OF PEDIATRICS
(2024)
Editorial Material
Pediatrics
Kanwaljit Singh, John Concato, Jonathan M. Davis
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Yaxing Meng, Harri Niinikoski, Suvi P. Rovio, Brooklyn J. Fraser, Feitong Wu, Antti Jula, Tapani Ronnemaa, Jorma S. A. Viikari, Olli T. Raitakari, Katja Pahkala, Costan G. Magnussen
Summary: This 26-year study shows a correlation between early-life non-HDL-C levels and future levels. Early dietary counseling can reduce the risk of high pediatric non-HDL-C, emphasizing the importance of early interventions in preventing cardiovascular risks.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Kelsey A. B. Gastineau, Rebecca Bell, Allison Hanes, Sandra Mckay, Eric Sigel, Filoteia Popescu, Evan C. Sommer, Shari Barkin
Summary: This study aimed to assess the self-reported counseling outcomes for a firearm safe storage counseling training program provided by the American Academy of Pediatrics. The results demonstrated significant improvement in counseling self-efficacy and frequency one month after the training.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Kathryn E. K. Berlin, William Scott, Sara Dawson, David Brousseau, Joanne M. Lagatta
Summary: This prospective cohort study aimed to investigate the impact of bronchopulmonary dysplasia (BPD) on the health-related quality of life (HRQL) of infants from NICU hospitalization to one year post-discharge. The study found that lower HRQL during NICU stay was associated with earlier gestational age, postnatal corticosteroid usage, outborn status, and gastrostomy tube placement. Lower HRQL at 3 and 12 months post-discharge was associated with readmissions, home oxygen use, parent-reported difficulty breathing, lower developmental scores, and not playing with other children. Most parents reported similar or improved HRQL after discharge, but parents of infants with respiratory symptoms experienced less improvement. Efforts to improve parent HRQL should focus on respiratory symptoms and social isolation.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Garett J. Griffith, Alan P. Wang, Robert I. Liem, Michael R. Carr, Tyler Corson, Kendra Ward
Summary: This study developed reference values for cardiorespiratory fitness in children aged 6-18 years without underlying heart disease, measured by peak oxygen uptake and treadmill time. Fitness levels increased with age in males but not females. Males generally exhibited higher fitness levels compared to females in the same age groups.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
David S. Liu, Patricia Miller, Anna Rothenberg, Carley Vuillermin, Peter M. Waters, Andrea S. Bauer
Summary: This study aims to determine if children with elbow flexion contracture (EFC) caused by brachial plexus birth injury (BPBI) are more likely to develop shoulder contracture and undergo surgical treatment. A retrospective review was conducted on children under 2 years old with BPBI who presented to a single children's hospital. The results showed that patients with EFC had reduced shoulder range of motion and higher odds of shoulder contracture and surgical treatment. Prompt referral to a BPBI specialty clinic is recommended for evaluation and potential surgery.
JOURNAL OF PEDIATRICS
(2024)