Article
Environmental Sciences
Christina Lombardi, Shiraya Thompson, Beate Ritz, Myles Cockburn, Julia E. Heck
Summary: The study suggests that residential proximity to agricultural pesticide applications during pregnancy may increase the risk of childhood central nervous system tumors. Elevated risks were observed for several specific pesticides in relation to different types of childhood brain tumors.
ENVIRONMENTAL RESEARCH
(2021)
Article
Nutrition & Dietetics
Melissa K. Blake, Ruixuan Ma, Erika Viana Cardenas, Parisa Varanloo, Yaray Agosto, Carolina Velasquez, Katheryn A. Espina, Joanne Palenzuela, Sarah E. Messiah, Ruby A. Natale
Summary: This study investigated the association between age at solid food initiation and obesity prevalence in preschool-aged children, taking into account disability status, ethnicity, gestational age, and birth weight. The findings revealed no significant difference in obesity prevalence based on age at solid food introduction. Children with disabilities and preterm births had significantly lower odds of being obese, while Hispanic children and those with higher birth weights were more likely to be obese.
Article
Oncology
Anne Sophie Lind Helligsoe, Line Kenborg, Louise Tram Henriksen, Aparna Udupi, Henrik Hasle, Jeanette Falck Winther
Summary: Incidence rates of childhood CNS tumors in Denmark remain stable but among the highest in the world. Despite improved survival rates in recent years for children aged 0-4 years, some subtypes still have a poor prognosis.
Review
Oncology
Yafeng Wang, Yiran Xu, Changlian Zhu
Summary: Autophagy is a physiological process that plays a complex role in cancer. Understanding autophagy mechanisms is important for the treatment of pediatric central nervous system tumors.
CURRENT TREATMENT OPTIONS IN ONCOLOGY
(2022)
Article
Multidisciplinary Sciences
Maral Adel Fahmideh, Erin C. Peckham-Gregory, Jeremy M. Schraw, Murali Chintagumpala, Stephen C. Mack, Philip J. Lupo, Michael E. Scheurer
Summary: The study investigated the impact of maternal and perinatal factors on the risk and survival of pediatric CNS tumors. Results indicated that ethnicity and perinatal characteristics play a significant role in the etiology and survival of these tumors.
SCIENTIFIC REPORTS
(2021)
Article
Oncology
Neige Marie Yvanne Journy, Wael Salem Zrafi, Stephanie Bolle, Brice Fresneau, Claire Alapetite, Rodrigue Setcheou Allodji, Delphine Berchery, Nadia Haddy, Isao Kobayashi, Martine Labbe, Helene Pacquement, Claire Pluchart, Boris Schwartz, Vincent Souchard, Cecile Thomas-Teinturier, Cristina Veres, Giao Vu-Bezin, Ibrahima Diallo, Florent de Vathaire
Summary: Childhood or adolescent cancer survivors undergoing cranial irradiation are at increased risk of developing subsequent primary neoplasms of the central nervous system (CNS), particularly meningiomas, and the risk is significantly associated with radiation dose. Monitoring patients with cranial irradiation should continue for at least 30 years post-treatment to ensure early detection and intervention. Identified risk factors, such as radiation dose and cumulative alkylating agents, can help inform long-term surveillance strategies for this population.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2021)
Article
Oncology
Wuqing Huang, Kristina Sundquist, Jan Sundquist, Jianguang Ji
Summary: Children of survivors with CNS tumor before the age of 20 did not show a significantly higher risk of overall somatic diseases compared to population controls. However, children with a paternal diagnosis of CNS tumor had a significantly increased risk of malignancies, infectious, and parasitic diseases.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Review
Public, Environmental & Occupational Health
Thanh T. Hoang, Elizabeth Whitcomb, Erin E. Reardon, Logan G. Spector, Philip J. Lupo, Michael E. Scheurer, Lindsay A. Williams
Summary: The purpose of this review is to summarize the current literature on risk factors related to childhood central nervous system tumors (cCNSt). The strongest risk factor found is exposure to ionizing radiation from medical devices, while there are positive associations with factors such as maternal age, birth weight, and pesticide exposure. Conversely, maternal folic acid supplementation during pregnancy and having childhood allergic conditions are inversely associated with cCNSt. However, further research is needed to assess the risk factors by molecular and histological subtypes as well as to improve exposure assessments.
CURRENT EPIDEMIOLOGY REPORTS
(2022)
Article
Medicine, General & Internal
Yulika Yoshida-Montezuma, Branavan Sivapathasundaram, Hilary K. Brown, Charles Keown-Stoneman, Russell J. de Souza, Teresa To, Cornelia M. Borkhoff, Catherine S. Birken, Jonathon L. Maguire, Laura N. Anderson
Summary: Children born late preterm and moderately preterm have higher cardiometabolic risk, suggesting that screening and early-life interventions for these children may prevent cardiometabolic outcomes.
Article
Pediatrics
Revathi Rajagopal, Daniel C. Moreira, Lane Faughnan, Huiqi Wang, Sameen Naqvi, Lisa Krull, Liliana Vasquez, Rosdali Diaz-Coronado, Michael Terao, Meenakshi Devidas, Ibrahim Qaddoumi
Summary: Childhood central nervous system tumors are often diagnosed later due to a lack of awareness among healthcare providers about their clinical presentations. A global survey revealed significant knowledge gaps among healthcare providers regarding childhood CNS tumors, highlighting the importance of educational strategies to improve their understanding of these tumors' clinical presentations.
EUROPEAN JOURNAL OF PEDIATRICS
(2022)
Article
Oncology
George Lambrou, Apostolos Zaravinos, Maria Braoudaki
Summary: The study aimed to identify commonly dysregulated miRNAs across different types of pediatric CNS tumors. Results showed that certain miRNAs were globally up- or down-regulated in the majority of CNS tumor samples, with specific miRNAs able to distinguish between tumors and normal brain tissue. The approach could be significant for identifying global miRNA targets for tumor diagnosis and therapy, with no previous reports of this specific approach found in literature.
Article
Oncology
Pascal Petit, Gerald Gandon, Stephan Chabardes, Vincent Bonneterre
Summary: This study investigated the associations between agricultural activities and central nervous system (CNS) tumors in the French farm manager workforce. The findings indicate that several agricultural activities, particularly animal farming, are associated with an increased risk of CNS tumors.
INTERNATIONAL JOURNAL OF CANCER
(2022)
Article
Public, Environmental & Occupational Health
Andrew Wooyoung Kim, Bernard Kakuhikire, Charles Baguma, Crystal M. North, Emily N. Satinsky, Jessica M. Perkins, Patience Ayebare, Allen Kiconco, Elizabeth B. Namara, David R. Bangsberg, Mark J. Siedner, Alexander C. Tsai
Summary: This study evaluated the associations between adverse childhood experiences and adult cardiometabolic risk factors and health outcomes in a population-based study of rural Ugandan adults. Results showed no significant associations between adverse childhood experiences and a range of adult cardiometabolic risk factors and health outcomes in this sample. Further research is needed to identify potential pathways and protective factors against adverse cardiometabolic and cardiovascular health outcomes in this population.
JOURNAL OF GLOBAL HEALTH
(2021)
Article
Nanoscience & Nanotechnology
Yotaro Kitano, Kosuke Aoki, Fumiharu Ohka, Shintaro Yamazaki, Kazuya Motomura, Kuniaki Tanahashi, Masaki Hirano, Tsuyoshi Naganawa, Mikiko Iida, Yukihiro Shiraki, Tomohide Nishikawa, Hiroyuki Shimizu, Junya Yamaguchi, Sachi Maeda, Hidenori Suzuki, Toshihiko Wakabayashi, Yoshinobu Baba, Takao Yasui, Atsushi Natsume
Summary: There is currently a lack of accurate mass screening methods for early detection of central nervous system tumors. Research suggests that liquid biopsy based on urinary microRNAs may be an effective screening method, with high sensitivity and specificity in differentiating patients from noncancer individuals.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Endocrinology & Metabolism
Maria Pineros-Leano, Natalie Grafft, Liliana Aguayo
Summary: This study examines the factors at the child and maternal levels that are associated with the growth trajectories of White, Black, and Latino children. The study found racial/ethnic differences in the risk factors for childhood obesity, with fast-food consumption being associated with at-risk trajectories for White children, and prepregnancy BMI being associated with at-risk trajectories for Black and Latino children.
Article
Environmental Sciences
Julie Von Behren, Michelle Wong, Daniela Morales, Peggy Reynolds, Paul B. English, Gina Solomon
Summary: After the Paradise wildfire, researchers conducted a study on tap water in the area and provided participants with customized laboratory reports. The study found that participants were satisfied with the communication of the results and felt less worried about their drinking water quality. Some participants even took action based on the results they received.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Oncology
Santhosh A. Upadhyaya, Olivia Campagne, Catherine A. Billups, Brent A. Orr, Arzu Onar-Thomas, Ruth G. Tatevossian, Roya Mostafavi, Jason R. Myers, Anna Vinitsky, Daniel C. Moreira, Holly B. Lindsay, Lindsay Kilburn, Patricia Baxter, Amy Smith, John R. Crawford, Sonia Partap, Anne E. Bendel, Dolly G. Aguilera, Kim E. Nichols, Evadnie Rampersaud, David W. Ellison, Paul Klimo, Zoltan Patay, Giles W. Robinson, Alberto Broniscer, Clinton F. Stewart, Cynthia Wetmore, Amar Gajjar
Summary: This study examines the use of Aurora kinase A inhibitor alisertib in children with recurrent AT/RT. The results show that alisertib is well tolerated in children with recurrent AT/RT, and approximately one-third of the patients observed stable disease or partial response.
Article
Oncology
Jena Lilly, Jo Lynne Rokita, Jennifer L. Mason, Tatiana Patton, Stephanie Stefankiewiz, David Higgins, Gerri Trooskin, Carina A. Larouci, Kamnaa Arya, Elizabeth Appert, Allison P. Heath, Yuankun Zhu, Miguel A. Brown, Bo Zhang, Bailey K. Farrow, Shannon Robins, Allison M. Morgan, Thinh Q. Nguyen, Elizabeth Frenkel, Kaitlin Lehmann, Emily Drake, Catherine Sullivan, Alexa Plisiewicz, Noel Coleman, Luke Patterson, Mateusz Koptyra, Zeinab Helili, Nicholas Van Kuren, Nathan Young, Meen Chul Kim, Christopher Friedman, Alex Lubneuski, Christopher Blackden, Marti Williams, Valerie Baubet, Lamiya Tauhid, Jamie Galanaugh, Katie Boucher, Heba Ijaz, Kristina A. Cole, Namrata Choudhari, Mariarita Santi, Robert W. Moulder, Jonathan Waller, Whitney Rife, Sharon J. Diskin, Marion Mateos, Donald W. Parsons, Ian F. Pollack, Stewart Goldman, Sarah Leary, Chiara Caporalini, Anna Maria Buccoliero, Mirko Scagnet, David Haussler, Derek Hanson, Ron Firestein, Jason Cain, Joanna J. Phillips, Nalin Gupta, Sabine Mueller, Gerald Grant, Michelle Monje-Deisseroth, Sonia Partap, Jeffrey P. Greenfield, Rintaro Hashizume, Amy Smith, Shida Zhu, James M. Johnston, Jason R. Fangusaro, Matthew Miller, Matthew D. Wood, Sharon Gardner, Claire L. Carter, Laura M. Prolo, Jared Pisapia, Katherine Pehlivan, Andrea Franson, Toba Niazi, Josh Rubin, Mohamed Abdelbaki, David S. Ziegler, Holly B. Lindsay, Ana Guerreiro Stucklin, Nicolas Gerber, Olena M. Vaske, Carolyn Quinsey, Brian R. Rood, Javad Nazarian, Eric Raabe, Eric M. Jackson, Stacie Stapleton, Robert M. Lober, David E. Kram, Carl Koschmann, Phillip B. Storm, Rishi R. Lulla, Michael Prados, Adam C. Resnick, Angela J. Waanders
Summary: Pediatric brain tumors are the leading cause of cancer-related death in children in the United States and the Children's Brain Tumor Network (CBTN) is a multi-institutional international clinical research consortium created to advance therapeutic development through the collection and rapid distribution of biospecimens and data.
Article
Oncology
Shannon M. Conroy, Julie Von Behren, Marilyn L. Kwan, Lawrence H. Kushi, Mi-Ok Kim, Carlos Iribarren, Janise M. Roh, Cecile A. Laurent, Catherine Thomsen, Janet N. Chu, Heather Greenlee, Scarlett Lin Gomez, Salma Shariff-Marco
Summary: This study examined the impact of social and built neighborhood attributes on cardiovascular disease (CVD) risk in female breast cancer survivors. The results showed that neighborhood racial/ethnic composition and crime index were independently associated with the risk of CVD events in these survivors, regardless of individual factors such as socioeconomic status and treatment.
Editorial Material
Oncology
Paul Graham Fisher
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Jasia Mahdi, Jorg Dietrich, Karin Straathof, Claire Roddie, Brian J. Scott, Tom Belle Davidson, Laura M. Prolo, Tracy T. Batchelor, Cynthia J. Campen, Kara L. Davis, Juliane Gust, Michael Lim, Robbie G. Majzner, Julie R. Park, Sonia Partap, Sneha Ramakrishna, Rebecca Richards, Liora Schultz, Nicholas A. Vitanza, Leo D. Wang, Crystal L. Mackall, Michelle Monje
Summary: Cancer immunotherapies can cause unique toxicities and it is important to establish grading scales and standardized treatment algorithms to improve safety. The authors propose a new toxicity syndrome called tumor inflammation-associated neurotoxicity (TIAN) in patients treated with cell therapies for CNS tumors. They also suggest a grading scale and discuss management strategies to standardize reporting and treatment for this syndrome.
Meeting Abstract
Oncology
Tara Barron, Belgin Yalcin, Aaron Mochizuki, Evan Cantor, Kiarash Shamardani, Dana Tlais, Andrea Franson, Samantha Lyons, Vilina Mehta, Samin Maleki Jahan, Kathryn Taylor, Michael Keough, Haojun Xu, Minhui Su, Michael Quezada, Pamelyn Woo, Paul Fisher, Cynthia Campen, Sonia Partap, Carl Koschmann, Michelle Monje
Meeting Abstract
Oncology
Jasia Mahdi, Jorg Dietrich, Karin Straathof, Claire Roddie, Brian Scott, Tom Belle Davidson, Laura Prolo, Tracy Batchelor, Cynthia Campen, Kara Davis, Juliane Gust, Michael Lim, Robbie Majzner, Julie Park, Sonia Partap, Sneha Ramakrishna, Rebecca Richards, Liora Schultz, Nicholas Vitanza, Leo Wang, Crystal Mackall, Michelle Monje
Meeting Abstract
Oncology
Jason Chiang, Aditi Bagchi, Xiaoyu Li, Sandeep K. Dhanda, Jie Huang, Soniya N. Pinto, Edgar Sioson, Sonia Partap, Paul G. Fisher, Daniel C. Bowers, Timothy E. G. Hassall, Congyu Lu, Airen Zaldivar-Peraza, Karen D. Wright, Noah D. Sabin, Brent A. Orr, Arzu Onar-Thomas, Xin Zhou, David W. Ellison, Amar Gajjar, Giles W. Robinson
Article
Oncology
Dana Tlais, Maria Isabel Barros Guinle, Joshua Riley Wheeler, Laura M. Prolo, Hannes Vogel, Sonia Partap
Summary: This study reviewed 3 pediatric patients with CNS tumors having CHEK2 mutations. Germline testing in 1 case confirmed the hereditary nature of CHEK2 mutation. The study suggests that CHEK2 may contribute to carcinogenesis and reporting similar cases may help identify a new molecular driver in pediatric CNS tumors.
NEURO-ONCOLOGY ADVANCES
(2023)
Article
Oncology
Daniel C. Bowers, Veena Rajaram, Matthias A. Karajannis, Sharon L. Gardner, Jack Meng-Fen Su, Patricia Baxter, Sonia Partap, Laura J. Klesse
Summary: This phase II clinical trial evaluated the efficacy of everolimus, an mTOR pathway inhibitor, for children with recurrent or progressive posterior fossa-A (PF-A) ependymomas. The study showed that everolimus did not lead to objective tumor responses in these patients. Adverse events were generally mild, with only one case of grade 3 pneumonia.
NEURO-ONCOLOGY ADVANCES
(2023)
Meeting Abstract
Oncology
Robbie G. Majzner, Jasia Mahdi, Sneha Ramakrishna, Shabnum Patel, Harshini Chinnasamy, Kristen Yeom, Liora Schultz, Valentin Barsan, Rebecca Richards, Cynthia Campen, Agnes Reschke, Angus Martin Shaw Toland, Christina Baggott, Sharon Mavroukakis, Emily Egeler, Jennifer Moon, Ashley Jacobs, Karen Yamabe-Kwong, Lindsey Rasmussen, Esther Nie, Sean Green, Michael Kunicki, Michelle Fujimoto, Zach Ehlinger, Warren Reynolds, Snehit Prabhu, Katherine E. Warren, Tim Cornell, Sonia Partap, Paul Fisher, Gerald Grant, Hannes Vogel, Bita Sahaf, Kara Davis, Steven Feldman, Michelle Monje, Crystal L. Mackall
Article
Oncology
Amar Gajjar, Anita Mahajan, Mohamed Abdelbaki, Clarke Anderson, Reuben Antony, Tejus Bale, Ranjit Bindra, Daniel C. Bowers, Kenneth Cohen, Bonnie Cole, Kathleen Dorris, Ralph Ermoian, Andrea Franson, Jeffrey Helgager, Daniel Landi, Chi Lin, Laura Metrock, Ronica Nanda, Joshua Palmer, Sonia Partap, Ashley Plant, Sumit Pruthi, Renee Reynolds, Paul Ruggieri, Duncan Stearns, Phillip Storm, Anthony Wang, Katherine Warren, Nicholas Whipple, Wafik Zaky, Nicole R. McMillian, Lenora A. Pluchino
Summary: Central nervous system (CNS) cancers, particularly high-grade gliomas, are a significant concern in pediatric oncology. Despite advancements in molecular profiling, the prognosis for these aggressive tumors remains poor, highlighting the importance of clinical trials for eligible patients.
JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK
(2022)
Meeting Abstract
Oncology
Sonia Partap, Natasha Abadilla, Thrithi Farahzadi, Michelle Monje
Meeting Abstract
Oncology
Lindsey M. Hoffman, Jean Mulcahy Levy, Lindsay Kilburn, Catherine Billups, Vanetria Stokes, Emily McCourt, Tina Young Poussaint, Olivia Campagne, Sonia Partap, Kathleen Dorris, Sameer Farouk Sait, Giles Robinson, Patricia Baxter, Clinton F. Stewart, Jason Fangusaro, Arzu Onar-Thomas, Ira Dunkel
Article
Pediatrics
Tarun Aurora, Audrey Cole, Parul Rai, Paul Lavoie, Carrie Mcivor, Lisa M. Klesges, Guolian Kang, Janaka S. S. Liyanage, Heather M. Brandt, Jane S. Hankins
Summary: This study evaluated the effectiveness of a vaccine strategy bundle in increasing HPV vaccine initiation and completion rates in a specialty clinic setting. By implementing the bundle, which included staff education, provider incentives, offering vaccines in clinics, and verifying vaccine completion, the clinic successfully improved HPV vaccine initiation and completion rates among sickle cell disease patients.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Nienke M. Halbmeijer, Wes Onland, Jeroen Dudink, Filip Cools, Anne Debeer, Anton H. van Kaam, Manon J. N. L. Benders, Niek E. van der Aa
Summary: In ventilated infants born preterm, high dose systemic hydrocortisone initiated between 7 and 14 days after birth did not have a significant impact on brain development.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Katherine Melton, Jianfang Liu, Hossein Sadeghi, Maureen George, Arlene Smaldone
Summary: This study aims to identify predictors of change in lung function and body weight during health care transition in cystic fibrosis (CF) patients. The study findings highlight the importance of CF RISE program engagement and reducing gaps in care for improving the transition of adolescents and young adults with CF.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Laura A. Duckworth, Kimberly A. Sutton, Nurmohammad Shaikh, Jinli Wang, Carla Hall-Moore, Lori R. Holtz, Phillip I. Tarr, Ronald C. Rubenstein
Summary: The study tested the usefulness of various biomarkers as indicators of gut dysfunction in cystic fibrosis (CF) and investigated the repeatability of these measures in individuals over short periods and their correlation with clinical outcomes. The results showed that elevated levels of fLcn2 in individuals with CF may predict worsened pulmonary function.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Lindsey Haack, Nikkan Das, Arvind Hoskoppal, Mark Debrunner, Tarek Alsaied, Gaurav Arora
Summary: RAE on ECG has a low positive predictive value for RAE on echocardiogram in previously healthy young patients. The highest yield for RAE on echocardiogram was observed in patients who were <1 year of age, had RAE in the anterior precordial leads, or displayed right ventricular hypertrophy on ECG.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Michael A. Padula, Khatija Naing, Tara L. Wenger, Irfan Ahmad, Carl H. Coghill, K. Taylor Wild, S. Alex Rottgers, Cory M. Resnick, Jeffrey Goldstein, Zarmina Ehsan, Donna Watkins, Nicole Deptula, Kuan-Chi Lai, Janet Lioy, Semsa Gogcu, Christopher M. Cielo
Summary: This study describes the spectrum of disease and burden of care in infants with congenital micrognathia. The results show that these infants commonly require surgical intervention and tube feedings, and disparities based on race and among centers were identified.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Michael P. Fundora, Manvitha Kalicheti, Guantao Zhao, Kevin O. Maher, Nicoleta Serban
Summary: This study investigated the variation of outpatient opioid prescribing in postoperative pediatric cardiac patients across the US. The results showed that there were significant differences in opioid prescribing by race, ethnicity, sex, and region.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Jia Guo, Brooklyn J. Fraser, Leigh Blizzard, Michael D. Schmidt, Terence Dwyer, Alison J. Venn, Costan G. Magnussen
Summary: There is a correlation between childhood and adulthood cardiorespiratory fitness.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Nianzhou Xiao, Michelle Starr, Adrienne Stolfi, Gilad Hamdani, Shireen Hashmat, Stefan G. Kiessling, Christina Sethna, Mahmoud Kallash, Robyn Matloff, Robert Woroniecki, Keia Sanderson, Ikuyo Yamaguchi, Stephen D. Cha, Michael G. Semanik, Rahul Chanchlani, Joseph T. Flynn, Mark Mitsnefes
Summary: This multicenter study reports that most infants diagnosed with idiopathic hypertension in the NICU will discontinue antihypertensive treatment within 2 years of discharge. Antenatal steroid treatment is associated with a decreased likelihood of needing antihypertensive therapy for more than 1 year.
JOURNAL OF PEDIATRICS
(2024)
Editorial Material
Pediatrics
Kanwaljit Singh, John Concato, Jonathan M. Davis
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Yaxing Meng, Harri Niinikoski, Suvi P. Rovio, Brooklyn J. Fraser, Feitong Wu, Antti Jula, Tapani Ronnemaa, Jorma S. A. Viikari, Olli T. Raitakari, Katja Pahkala, Costan G. Magnussen
Summary: This 26-year study shows a correlation between early-life non-HDL-C levels and future levels. Early dietary counseling can reduce the risk of high pediatric non-HDL-C, emphasizing the importance of early interventions in preventing cardiovascular risks.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Kelsey A. B. Gastineau, Rebecca Bell, Allison Hanes, Sandra Mckay, Eric Sigel, Filoteia Popescu, Evan C. Sommer, Shari Barkin
Summary: This study aimed to assess the self-reported counseling outcomes for a firearm safe storage counseling training program provided by the American Academy of Pediatrics. The results demonstrated significant improvement in counseling self-efficacy and frequency one month after the training.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Kathryn E. K. Berlin, William Scott, Sara Dawson, David Brousseau, Joanne M. Lagatta
Summary: This prospective cohort study aimed to investigate the impact of bronchopulmonary dysplasia (BPD) on the health-related quality of life (HRQL) of infants from NICU hospitalization to one year post-discharge. The study found that lower HRQL during NICU stay was associated with earlier gestational age, postnatal corticosteroid usage, outborn status, and gastrostomy tube placement. Lower HRQL at 3 and 12 months post-discharge was associated with readmissions, home oxygen use, parent-reported difficulty breathing, lower developmental scores, and not playing with other children. Most parents reported similar or improved HRQL after discharge, but parents of infants with respiratory symptoms experienced less improvement. Efforts to improve parent HRQL should focus on respiratory symptoms and social isolation.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Garett J. Griffith, Alan P. Wang, Robert I. Liem, Michael R. Carr, Tyler Corson, Kendra Ward
Summary: This study developed reference values for cardiorespiratory fitness in children aged 6-18 years without underlying heart disease, measured by peak oxygen uptake and treadmill time. Fitness levels increased with age in males but not females. Males generally exhibited higher fitness levels compared to females in the same age groups.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
David S. Liu, Patricia Miller, Anna Rothenberg, Carley Vuillermin, Peter M. Waters, Andrea S. Bauer
Summary: This study aims to determine if children with elbow flexion contracture (EFC) caused by brachial plexus birth injury (BPBI) are more likely to develop shoulder contracture and undergo surgical treatment. A retrospective review was conducted on children under 2 years old with BPBI who presented to a single children's hospital. The results showed that patients with EFC had reduced shoulder range of motion and higher odds of shoulder contracture and surgical treatment. Prompt referral to a BPBI specialty clinic is recommended for evaluation and potential surgery.
JOURNAL OF PEDIATRICS
(2024)