Journal
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
Volume 32, Issue 8, Pages 579-584Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MPH.0b013e3181edb464
Keywords
Gorham-Stout disease; pleural effusion; zoledronic acid; interferon alpha
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Gorham-Stout disease is a rare disease characterized by osteolysis, angiomatosis, and soft-tissue swelling. It is a diagnosis of exclusion and has an unknown etiology. Chylothorax is a common complication of the disease that is associated with a high mortality rate. There is no standard of treatment. We report a case of a 16-year-old female with Gorham-Stout disease and recurrent pleural effusions who was successfully treated with concurrent zoledronic acid and peg-interferon alpha-2b.
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