Epidermal overexpression of transgenic ΔNp63 promotes type 2 immune and myeloid inflammatory responses and hyperplasia via NF-κB activation

Aberrant IKKα and IKKβ cooperatively activate NF-κB and induce EGFR/AP1 signaling to promote survival and migration of head and neck cancer

(2013) L K Nottingham et al.   ONCOGENE

UV-induced ablation of the epidermal basal layer including p53-mutant clones resets UV carcinogenesis showing squamous cell carcinomas to originate from interfollicular epidermis

(2012) H.G. Rebel et al.   CARCINOGENESIS

 Np63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation

(2012) R.-A. Romano et al.   DEVELOPMENT

Phenotypic and functional characteristics of CD4+CD39+ FOXP3+ and CD4+CD39+FOXP3neg T-cell subsets in cancer patients

(2012) Patrick J. Schuler et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

NF- B, the first quarter-century: remarkable progress and outstanding questions

(2012) M. S. Hayden et al.   GENES & DEVELOPMENT

NF-κB and the link between inflammation and cancer

(2012) Joseph A. DiDonato et al.   IMMUNOLOGICAL REVIEWS

The Pro-inflammatory Role of TGFβ1: A Paradox?

(2012) Gangwen Han et al.   International Journal of Biological Sciences

TGF-β and NF-κB signal pathway cross-talk is mediated through TAK1 and SMAD7 in a subset of head and neck cancers

(2012) C Freudlsperger et al.   ONCOGENE

Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage

(2011) S. I. Grivennikov et al.   ANNALS OF THE RHEUMATIC DISEASES

Multifaceted link between cancer and inflammation

(2011) Gautam Sethi et al.   BIOSCIENCE REPORTS

Roles of the immune system in skin cancer

(2011) S. Rangwala et al.   BRITISH JOURNAL OF DERMATOLOGY

TNF-  Promotes c-REL/ Np63  Interaction and TAp73 Dissociation from Key Genes That Mediate Growth Arrest and Apoptosis in Head and Neck Cancer

(2011) H. Lu et al.   CANCER RESEARCH

 Np63 Versatilely Regulates a Broad NF- B Gene Program and Promotes Squamous Epithelial Proliferation, Migration, and Inflammation

(2011) X. Yang et al.   CANCER RESEARCH

Immune responses in the skin in old age

(2011) Milica Vukmanovic-Stejic et al.   CURRENT OPINION IN IMMUNOLOGY

ΔNp63α Protein Triggers Epithelial-Mesenchymal Transition and Confers Stem Cell Properties in Normal Human Keratinocytes

(2011) Ju-Eun Oh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemokine Receptor 7 (CCR7) Gene Expression Is Regulated by NF-κB and Activator Protein 1 (AP1) in Metastatic Squamous Cell Carcinoma of Head and Neck (SCCHN)

(2011) Yvonne K. Mburu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The chemokine system and cancer

(2011) Frances R Balkwill   JOURNAL OF PATHOLOGY

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Macrophages, innate immunity and cancer: balance, tolerance, and diversity

(2010) Alberto Mantovani et al.   CURRENT OPINION IN IMMUNOLOGY

Abnormal hair follicle development and altered cell fate of follicular keratinocytes in transgenic mice expressing  Np63 

(2010) R. A. Romano et al.   DEVELOPMENT

NF-κB as a central regulator of macrophage function in tumors

(2010) Subhra K. Biswas et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

Current and potential inflammation targeted therapies in head and neck cancer

(2009) Frederick Wang et al.   CURRENT OPINION IN PHARMACOLOGY

Activated macrophages in the tumour microenvironment-dancing to the tune of TLR and NF-κB

(2009) Simon Hallam et al.   JOURNAL OF PATHOLOGY

An Active Role of the ΔN Isoform of p63 in Regulating Basal Keratin Genes K5 and K14 and Directing Epidermal Cell Fate

(2009) Rose-Anne Romano et al.   PLoS One

The p53 Homologue  Np63  Interacts with the Nuclear Factor- B Pathway to Modulate Epithelial Cell Growth

(2008) K. E. King et al.   CANCER RESEARCH

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

The Interleukin-8 Pathway in Cancer

(2008) D. J.J. Waugh et al.   CLINICAL CANCER RESEARCH

The IκB kinase complex: master regulator of NF-κB signaling

(2008) Laura A. Solt et al.   IMMUNOLOGIC RESEARCH

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

A critical function for TGF-β signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells

(2008) Yongzhong Liu et al.   NATURE IMMUNOLOGY

TSLP acts on infiltrating effector T cells to drive allergic skin inflammation

(2008) R. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA