Ewing sarcoma inhibition by disruption of EWSR1-FLI1 transcriptional activity and reactivation of p53

Single Enantiomer of YK-4-279 Demonstrates Specificity in Targeting the Oncogene EWS-FLI1

(2015) Julie S. Barber-Rotenberg et al.   Oncotarget

Vemurafenib Synergizes with Nutlin-3 to Deplete Survivin and Suppresses Melanoma Viability and Tumor Growth

(2013) Z. Ji et al.   CLINICAL CANCER RESEARCH

Automated Whole Animal Bio-Imaging Assay for Human Cancer Dissemination

(2012) Veerander P. S. Ghotra et al.   PLoS One

Zebrafish Models for Cancer

(2011) Shu Liu et al.   Annual Review of Pathology-Mechanisms of Disease

Anticancer effects of the p53 activator nutlin-3 in Ewing’s sarcoma cells

(2011) Jürgen Sonnemann et al.   EUROPEAN JOURNAL OF CANCER

Mdm2 inhibition induces apoptosis in p53 deficient human colon cancer cells by activating p73- and E2F1-mediated expression of PUMA and Siva-1

(2010) Ramesh M. Ray et al.   APOPTOSIS

Nutlin-3a Is a Potential Therapeutic for Ewing Sarcoma

(2010) K. I. Pishas et al.   CLINICAL CANCER RESEARCH

Ewing's sarcoma

(2010) Naomi J Balamuth et al.   LANCET ONCOLOGY

Role of Mdm4 in drug sensitivity of breast cancer cells

(2010) S Lam et al.   ONCOGENE

Molecular characterization of commonly used cell lines for bone tumor research: A trans-European EuroBoNet effort

(2009) Laura Ottaviano et al.   GENES CHROMOSOMES & CANCER

A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma

(2009) Hayriye V Erkizan et al.   NATURE MEDICINE

COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer

(2009) Simon A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Comparative Transcriptome Analyses Revealed Conserved Biological and Transcription Factor Target Modules Between the Zebrafish and Human Tumors

(2009) Choong Yong Ung et al.   Zebrafish

Transparent Adult Zebrafish as a Tool for In Vivo Transplantation Analysis

(2008) Richard Mark White et al.   Cell Stem Cell

Distinct functions for ERK1 and ERK2 in cell migration processes during zebrafish gastrulation

(2008) S.F. Gabby Krens et al.   DEVELOPMENTAL BIOLOGY

Molecular abnormalities in Ewing’s sarcoma

(2008) Susan Ann Burchill   Expert Review of Anticancer Therapy

Zebrafish as a Cancer Model

(2008) H. Feitsma et al.   MOLECULAR CANCER RESEARCH

NK cells recognize and lyse Ewing sarcoma cells through NKG2D and DNAM-1 receptor dependent pathways

(2008) Dirk H.J. Verhoeven et al.   MOLECULAR IMMUNOLOGY