HOPX is methylated and exerts tumour-suppressive function through Ras-induced senescence in human lung cancer

Control of Alveolar Differentiation by the Lineage Transcription Factors GATA6 and HOPX Inhibits Lung Adenocarcinoma Metastasis

(2013) William K.C. Cheung et al.   CANCER CELL

Hopx expression defines a subset of multipotent hair follicle stem cells and a progenitor population primed to give rise to K6+ niche cells

(2013) N. Takeda et al.   DEVELOPMENT

Downregulation of HOPX Controls Metastatic Behavior in Sarcoma Cells and Identifies Genes Associated with Metastasis

(2013) Denisa Kovářová et al.   MOLECULAR CANCER RESEARCH

Cancer specific promoter CpG Islands hypermethylation of HOP homeobox (HOPX) gene and its potential tumor suppressive role in pancreatic carcinogenesis

(2012) Mina Waraya et al.   BMC CANCER

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Desmoplakin acts as a tumor suppressor by inhibition of the Wnt/β-catenin signaling pathway in human lung cancer

(2012) Linlin Yang et al.   CARCINOGENESIS

DSC3 expression is regulated by p53 and methylation of DSC3 DNA is a prognostic marker in human colorectal cancer

(2011) T Cui et al.   BRITISH JOURNAL OF CANCER

AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy

(2011) M V Astle et al.   ONCOGENE

Interconversion Between Intestinal Stem Cell Populations in Distinct Niches

(2011) N. Takeda et al.   SCIENCE

Potential utility of HOP homeobox gene promoter methylation as a marker of tumor aggressiveness in gastric cancer

(2010) A Ooki et al.   ONCOGENE

Homeobox gene HOPX is epigenetically silenced in human uterine endometrial cancer and suppresses estrogen-stimulated proliferation of cancer cells by inhibiting serum response factor

(2008) Shinichiro Yamaguchi et al.   INTERNATIONAL JOURNAL OF CANCER

HOP/OB1/NECC1 Promoter DNA Is Frequently Hypermethylated and Involved in Tumorigenic Ability in Esophageal Squamous Cell Carcinoma

(2008) K. Yamashita et al.   MOLECULAR CANCER RESEARCH