Cancer-associated somaticDICER1hotspot mutations cause defective miRNA processing and reverse-strand expression bias to predominantly mature 3p strands through loss of 5p strand cleavage

Strand-Specific miR-28-5p and miR-28-3p Have Distinct Effects in Colorectal Cancer Cells

(2012) Maria I. Almeida et al.   GASTROENTEROLOGY

The molecular architecture of human Dicer

(2012) Pick-Wei Lau et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

In vivo structure-function analysis of human Dicer reveals directional processing of precursor miRNAs

(2012) A. M. Gurtan et al.   RNA

Mirtrons, an emerging class of atypical miRNA

(2012) Helen J. Curtis et al.   Wiley Interdisciplinary Reviews-RNA

The role of the precursor structure in the biogenesis of microRNA

(2011) Julia Starega-Roslan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Ovarian sex cord-stromal tumors, pleuropulmonary blastoma and DICER1 mutations: A report from the International Pleuropulmonary Blastoma Registry

(2011) Kris Ann P. Schultz et al.   GYNECOLOGIC ONCOLOGY

Extending the phenotypes associated withDICER1mutations

(2011) William D. Foulkes et al.   HUMAN MUTATION

DICER1 syndrome: clarifying the diagnosis, clinical features and management implications of a pleiotropic tumour predisposition syndrome

(2011) I. Slade et al.   JOURNAL OF MEDICAL GENETICS

siRNA Repositioning for Guide Strand Selection by Human Dicer Complexes

(2011) Cameron L. Noland et al.   MOLECULAR CELL

Dicer recognizes the 5′ end of RNA for efficient and accurate processing

(2011) Jong-Eun Park et al.   NATURE

Recurrent SomaticDICER1Mutations in Nonepithelial Ovarian Cancers

(2011) Alireza Heravi-Moussavi et al.   NEW ENGLAND JOURNAL OF MEDICINE

The biogenesis and characterization of mammalian microRNAs of mirtron origin

(2011) Christopher R. Sibley et al.   NUCLEIC ACIDS RESEARCH

Deregulation of MYCN, LIN28B and LET7 in a Molecular Subtype of Aggressive High-Grade Serous Ovarian Cancers

(2011) Åslaug Helland et al.   PLoS One

miRNA Processing and Human Cancer: DICER1 Cuts the Mustard

(2011) A. Bahubeshi et al.   Science Translational Medicine

A Latent Pro-Survival Function for the Mir-290-295 Cluster in Mouse Embryonic Stem Cells

(2011) Grace X. Y. Zheng et al.   PLoS Genetics

Hsa-miR-125a-3p and hsa-miR-125a-5p are downregulated in non-small cell lung cancer and have inverse effects on invasion and migration of lung cancer cells

(2010) Lili Jiang et al.   BMC CANCER

Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidney

(2010) Vidya K. Nagalakshmi et al.   KIDNEY INTERNATIONAL

A Lentiviral Functional Proteomics Approach Identifies Chromatin Remodeling Complexes Important for the Induction of Pluripotency

(2010) Anthony B. Mak et al.   MOLECULAR & CELLULAR PROTEOMICS

Sequence features associated with microRNA strand selection in humans and flies

(2009) Hai Hu et al.   BMC GENOMICS

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Dicer is required for Sertoli cell function and survival

(2009) Gwang-Jin Kim et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Structural insights into RNA processing by the human RISC-loading complex

(2009) Hong-Wei Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Role of Dicer in female fertility

(2009) Lacey J. Luense et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Lentiviral Transduction of Mammary Stem Cells for Analysis of Gene Function during Development and Cancer

(2008) Bryan E. Welm et al.   Cell Stem Cell

Direct multiplexed measurement of gene expression with color-coded probe pairs

(2008) Gary K Geiss et al.   NATURE BIOTECHNOLOGY

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

(2008) Witold Filipowicz et al.   NATURE REVIEWS GENETICS