Nucleotide resolution analysis ofTMPRSS2andERGrearrangements in prostate cancer

IgH gene rearrangements as plasma biomarkers in Non-Hodgkin's Lymphoma patients

(2015) Jian He et al.   Oncotarget

Antibody-Based Detection of ERG Rearrangement-Positive Prostate Cancer

(2015) Kyung Park et al.   NEOPLASIA

A novel four-color fluorescence in situ hybridization assay for the detection of TMPRSS2 and ERG rearrangements in prostate cancer

(2013) Xiaoyu Qu et al.   Cancer Genetics

Clonal Progression of Prostate Cancers from Gleason Grade 3 to Grade 4

(2012) A. G. Sowalsky et al.   CANCER RESEARCH

Spatial Organization of the Mouse Genome and Its Role in Recurrent Chromosomal Translocations

(2012) Yu Zhang et al.   CELL

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Oncogene-mediated alterations in chromatin conformation

(2012) D. S. Rickman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of Chromosomal Alterations in the Circulation of Cancer Patients with Whole-Genome Sequencing

(2012) R. J. Leary et al.   Science Translational Medicine

Immunohistochemistry for ERG Expression as a Surrogate for TMPRSS2-ERG Fusion Detection in Prostatic Adenocarcinomas

(2011) Alcides Chaux et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Mechanistic Rationale for Inhibition of Poly(ADP-Ribose) Polymerase in ETS Gene Fusion-Positive Prostate Cancer

(2011) J. Chad Brenner et al.   CANCER CELL

Transcription-Induced DNA Double Strand Breaks: Both Oncogenic Force and Potential Therapeutic Target?

(2011) M. C. Haffner et al.   CLINICAL CANCER RESEARCH

Characterization of complex chromosomal rearrangements by targeted capture and next-generation sequencing

(2011) N. L. M. Sobreira et al.   GENOME RESEARCH

End Points and Outcomes in Castration-Resistant Prostate Cancer: From Clinical Trials to Clinical Practice

(2011) Howard I. Scher et al.   JOURNAL OF CLINICAL ONCOLOGY

Common Gene Rearrangements in Prostate Cancer

(2011) Mark A. Rubin et al.   JOURNAL OF CLINICAL ONCOLOGY

ERG gene rearrangements are common in prostatic small cell carcinomas

(2011) Tamara L Lotan et al.   MODERN PATHOLOGY

The genomic complexity of primary human prostate cancer

(2011) Michael F. Berger et al.   NATURE

How does DNA break during chromosomal translocations?

(2011) M. Nambiar et al.   NUCLEIC ACIDS RESEARCH

High-Throughput Detection of Actionable Genomic Alterations in Clinical Tumor Samples by Targeted, Massively Parallel Sequencing

(2011) Nikhil Wagle et al.   Cancer Discovery

ERG rearrangement is specific to prostate cancer and does not occur in any other common tumor

(2010) Veit J Scheble et al.   MODERN PATHOLOGY

Prevalence of TMPRSS2–ERG and SLC45A3–ERG gene fusions in a large prostatectomy cohort

(2010) Raquel Esgueva et al.   MODERN PATHOLOGY

Mutation spectrum revealed by breakpoint sequencing of human germline CNVs

(2010) Donald F Conrad et al.   NATURE GENETICS

Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements

(2010) Michael C Haffner et al.   NATURE GENETICS

Triggers for genomic rearrangements: insights into genomic, cellular and environmental influences

(2010) Ram-Shankar Mani et al.   NATURE REVIEWS GENETICS

ERG oncoprotein expression in prostate cancer: clonal progression of ERG-positive tumor cells and potential for ERG-based stratification

(2010) B Furusato et al.   PROSTATE CANCER AND PROSTATIC DISEASES

Development of Personalized Tumor Biomarkers Using Massively Parallel Sequencing

(2010) R. J. Leary et al.   Science Translational Medicine

Organization of Transcription

(2010) L. Chakalova et al.   Cold Spring Harbor Perspectives in Biology

A Role of DNA-PK for the Metabolic Gene Regulation in Response to Insulin

(2009) Roger H.F. Wong et al.   CELL

Nuclear Receptor-Induced Chromosomal Proximity and DNA Breaks Underlie Specific Translocations in Cancer

(2009) Chunru Lin et al.   CELL

Distinct genomic aberrations associated withERGrearranged prostate cancer

(2009) Francesca Demichelis et al.   GENES CHROMOSOMES & CANCER

Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing

(2009) Andreas Gnirke et al.   NATURE BIOTECHNOLOGY

Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer

(2009) Wennuan Liu et al.   NATURE MEDICINE

PSA as an intermediate end point in clinical trials

(2009) Gerhardt Attard et al.   Nature Reviews Urology

Induced Chromosomal Proximity and Gene Fusions in Prostate Cancer

(2009) R.-S. Mani et al.   SCIENCE

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

(2009) E. Lieberman-Aiden et al.   SCIENCE

Prostate-specific Antigen Bounce After Prostate Brachytherapy: Review of a Confusing Phenomenon

(2009) Murat Caloglu et al.   UROLOGY

Characterization of TMPRSS2:ETV5 and SLC45A3:ETV5 Gene Fusions in Prostate Cancer

(2008) B. E. Helgeson et al.   CANCER RESEARCH

Circulating mutant DNA to assess tumor dynamics

(2008) Frank Diehl et al.   NATURE MEDICINE

MMEJ repair of double-strand breaks (director’s cut): deleted sequences and alternative endings

(2008) Mitch McVey et al.   TRENDS IN GENETICS