Genomic and mutational profiling of ductal carcinomas in situ and matched adjacent invasive breast cancers reveals intra-tumour genetic heterogeneity and clonal selection

PIK3CA mutations rarely demonstrate genotypic intratumoral heterogeneity and are selected for in breast cancer progression

(2011) Kevin Kalinsky et al.   BREAST CANCER RESEARCH AND TREATMENT

LOXL2-Mediated Matrix Remodeling in Metastasis and Mammary Gland Involution

(2011) H. E. Barker et al.   CANCER RESEARCH

Genetic Interactions in Cancer Progression and Treatment

(2011) Alan Ashworth et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Immunophenotypic and genomic characterization of papillary carcinomas of the breast

(2011) Raphaëlle Duprez et al.   JOURNAL OF PATHOLOGY

Adenoid cystic carcinomas constitute a genomically distinct subgroup of triple-negative and basal-like breast cancers

(2011) Daniel Wetterskog et al.   JOURNAL OF PATHOLOGY

Gene expression profiling in breast cancer: classification, prognostication, and prediction

(2011) Jorge S Reis-Filho et al.   LANCET

Tumour evolution inferred by single-cell sequencing

(2011) Nicholas Navin et al.   NATURE

Challenges translating breast cancer gene signatures into the clinic

(2011) Britta Weigelt et al.   Nature Reviews Clinical Oncology

Molecular differences between ductal carcinoma in situ and adjacent invasive breast carcinoma: a multiplex ligation-dependent probe amplification study

(2011) Cathy B. Moelans et al.   CELLULAR ONCOLOGY

How Darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine

(2010) M Gerlinger et al.   BRITISH JOURNAL OF CANCER

PIK3CA Mutations in In situ and Invasive Breast Carcinomas

(2010) A. Miron et al.   CANCER RESEARCH

Breast cancer precursors revisited: molecular features and progression pathways

(2010) Maria A Lopez-Garcia et al.   HISTOPATHOLOGY

Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype

(2010) So Yeon Park et al.   JOURNAL OF CLINICAL INVESTIGATION

Mucinous carcinoma of the breast is genomically distinct from invasive ductal carcinomas of no special type

(2010) Magali Lacroix-Triki et al.   JOURNAL OF PATHOLOGY

Genome remodelling in a basal-like breast cancer metastasis and xenograft

(2010) Li Ding et al.   NATURE

Expression of miR-21 and its targets (PTEN, PDCD4, TM1) in flat epithelial atypia of the breast in relation to ductal carcinoma in situ and invasive carcinoma

(2009) Liqiang Qi et al.   BMC CANCER

Phosphatidylinositol-3-kinase and AKT1 mutations occur early in breast carcinoma

(2009) Jennifer Dunlap et al.   BREAST CANCER RESEARCH AND TREATMENT

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Phosphoinositide 3-Kinase Mutations in Breast Cancer: A "Good" Activating Mutation?

(2009) S. Di Cosimo et al.   CLINICAL CANCER RESEARCH

Tiling Path Genomic Profiling of Grade 3 Invasive Ductal Breast Cancers

(2009) R. Natrajan et al.   CLINICAL CANCER RESEARCH

Inferring tumor progression from genomic heterogeneity

(2009) N. Navin et al.   GENOME RESEARCH

Mixed micropapillary–ductal carcinomas of the breast: a genomic and immunohistochemical analysis of morphologically distinct components

(2009) Caterina Marchiò et al.   JOURNAL OF PATHOLOGY

Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas

(2009) Felipe C Geyer et al.   JOURNAL OF PATHOLOGY

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

(2009) Sohrab P. Shah et al.   NATURE

Regulation of In Situ to Invasive Breast Carcinoma Transition

(2008) Min Hu et al.   CANCER CELL

Integrated Genomic and Transcriptomic Analysis of Ductal Carcinoma In situ of the Breast

(2008) A. Vincent-Salomon et al.   CLINICAL CANCER RESEARCH

Ductal Carcinoma In situ and the Emergence of Diversity during Breast Cancer Evolution

(2008) D. C. Allred et al.   CLINICAL CANCER RESEARCH

Screening for copy-number alterations and loss of heterozygosity in chronic lymphocytic leukemia—A comparative study of four differently designed, high resolution microarray platforms

(2008) Rebeqa Gunnarsson et al.   GENES CHROMOSOMES & CANCER