Notch3 and kidney injury: never two without three

Fine-tuning of the intracellular canonical Notch signaling pathway

(2012) Tilman Borggrefe et al.   CELL CYCLE

Notch-3 receptor activation drives inflammation and fibrosis following tubulointerstitial kidney injury

(2012) Sonja Djudjaj et al.   JOURNAL OF PATHOLOGY

Notch2 and Notch3 Function Together to Regulate Vascular Smooth Muscle Development

(2012) Qingqing Wang et al.   PLoS One

Angiotensin II Contributes to Renal Fibrosis Independently of Notch Pathway Activation

(2012) Carolina Lavoz et al.   PLoS One

Notch signaling in human development and disease

(2012) Andrea L. Penton et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Notch receptor–ligand binding and activation: Insights from molecular studies

(2012) Chandramouli R. Chillakuri et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Non-canonical Notch signaling: emerging role and mechanism

(2012) Peter Andersen et al.   TRENDS IN CELL BIOLOGY

Notch3 Arg170Cys Knock-In Mice Display Pathologic and Clinical Features of the Neurovascular Disorder Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy

(2011) Goedele Wallays et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The EGF-like proteins DLK1 and DLK2 function as inhibitory non-canonical ligands of NOTCH1 receptor that modulate each other's activities

(2011) Beatriz Sánchez-Solana et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Elongin C is a mediator of Notch4 activity in human renal tubule cells

(2011) Timothy D. Cummins et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Current views on the role of Notch signaling and the pathogenesis of human leukemia

(2011) Joanna Pancewicz et al.   BMC CANCER

Mechanism and Significance of cis-Inhibition in Notch Signalling

(2011) David del Álamo et al.   CURRENT BIOLOGY

Notch3 Is Essential for Regulation of the Renal Vascular Tone

(2011) Nada Boulos et al.   HYPERTENSION

Notch signaling and Notch signaling modifiers

(2011) Michael M. Wang   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Notch in the kidney: development and disease

(2011) Yasemin Sirin et al.   JOURNAL OF PATHOLOGY

Notch Promotes Dynamin-Dependent Endocytosis of Nephrin

(2011) A. M. Waters et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease

(2011) J. F. Arboleda-Velasquez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIF Takes It Up a Notch

(2011) E. A. Johnson   Science Signaling

Activation of Notch signaling pathway in HIV-associated nephropathy

(2010) Madhulika Sharma et al.   AIDS

Jagged/Notch signalling is required for a subset of TGFβ1 responses in human kidney epithelial cells

(2010) Kristine C. Nyhan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Notch signaling pathway: Molecular basis of cell context dependency

(2010) Ralf Schwanbeck et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans

(2010) Bernhard Bielesz et al.   JOURNAL OF CLINICAL INVESTIGATION

Reduced Notch Signaling Leads to Renal Cysts and Papillary Microadenomas

(2010) K. Surendran et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mechanisms of Tubulointerstitial Fibrosis

(2010) M. Zeisberg et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

NF- B in Renal Inflammation

(2010) A. B. Sanz et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Expression of Notch pathway proteins correlates with albuminuria, glomerulosclerosis, and renal function

(2010) Mariana Murea et al.   KIDNEY INTERNATIONAL

Therapeutic antibody targeting of individual Notch receptors

(2010) Yan Wu et al.   NATURE

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

YB-1 Acts as a Ligand for Notch-3 Receptors and Modulates Receptor Activation

(2009) Thomas Rauen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nephroangiosclerosis in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy: Is NOTCH3 Mutation the Common Culprit?

(2008) Dominique Guerrot et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Modulation of Notch Signaling by Antibodies Specific for the Extracellular Negative Regulatory Region of NOTCH3

(2008) Kang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Angiotensin II activates the Smad pathway during epithelial mesenchymal transdifferentiation

(2008) Gisselle Carvajal et al.   KIDNEY INTERNATIONAL

Expression and function of the Delta-1/Notch-2/Hes-1 pathway during experimental acute kidney injury

(2008) T. Kobayashi et al.   KIDNEY INTERNATIONAL

The Notch pathway in podocytes plays a role in the development of glomerular disease

(2008) Thiruvur Niranjan et al.   NATURE MEDICINE

Pharmacological Modulation of Epithelial Mesenchymal Transition Caused by Angiotensin II. Role of ROCK and MAPK Pathways

(2008) Raquel Rodrigues-Díez et al.   PHARMACEUTICAL RESEARCH

Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice

(2008) P. A. Murphy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY