Article
Critical Care Medicine
Jared A. Greenberg, Santosh Basapur, Thomas Quinn, Jeffrey L. Bulger, Nathaniel H. Schwartz, Soo Kyung Oh, Ethan M. Ritz, Crystal M. Glover, Raj C. Shah
Summary: Daily written updates had a positive impact on the satisfaction and emotional well-being of families of ICU patients, supporting its use as a supplement to traditional communication approaches.
CRITICAL CARE MEDICINE
(2022)
Article
Nutrition & Dietetics
Hong-Yeul Lee, Jung-Kyu Lee, Hye-Jin Kim, Dal-Lae Ju, Sang-Min Lee, Jinwoo Lee
Summary: Continuous enteral feeding has been shown to be more effective in achieving target nutrition, especially in patients receiving mechanical ventilation.
Article
Nutrition & Dietetics
Jiajia Lin, Wensong Chen, Xianghong Ye, Cheng Lv, Yang Liu, Xingwei Jiang, Zhihui Tong, Yuxiu Liu, Lu Ke, Weiqin Li, Jieshou Li
Summary: This study evaluated the association between different trajectories of protein intake and 28-day mortality in critically ill patients. Results showed that low-level or high-level protein intake was associated with increased 28-day mortality compared to medium-level intake.
CLINICAL NUTRITION
(2022)
Article
Critical Care Medicine
Gonzalo Garcia Guerra, Ari R. Joffe, Cathy Sheppard, Krista Hewson, Irina A. Dinu, Morteza Hajihosseini, Allan DeCaen, Hsing Jou, Lisa Hartling, Sunita Vohra
Summary: This pilot RCT has shown the feasibility of a music medicine intervention in critically ill children and provided necessary information for planning a larger trial.
JOURNAL OF INTENSIVE CARE
(2021)
Article
Critical Care Medicine
Nicholas Heming, Robert Carlier, Helene Prigent, Ahmed Mekki, Camille Jousset, Frederic Lofaso, Xavier Ambrosi, Rania Bounab, Virginie Maxime, Arnaud Mansart, Pascal Crenn, Pierre Moine, Fabien Foltzer, Bernard Cuenoud, Tobias Konz, John Corthesy, Maurice Beaumont, Mickael Hartweg, Claudia Roessle, Jean-Charles Preiser, Denis Breuille, Djillali Annane
Summary: Muscle wasting is a common issue in prolonged critical illness. Supplementation with a tailored blend of amino acids can improve gut defense, intestinal mucosa repair, and reduce muscle loss.
Article
Multidisciplinary Sciences
Thierry Fumeaux, Claudia Berger, Alexander Bausch, Matthew Wright, Urosh Vilimanovich, Ivan Soldatovic, Maria J. G. T. Vehreschild
Summary: The combination of pamapimod and pioglitazone did not have a significant effect on the clinical outcome of COVID-19 patients, although it was safe and well-tolerated.
Article
Health Care Sciences & Services
Johan H. Vlake, Jasper van Bommel, Evert-Jan Wils, Joe Bienvenu, Merel E. Hellemons, Tim I. M. Korevaar, Anna F. C. Schut, Joost A. M. Labout, Lois L. H. Schreuder, Marten P. van Bavel, Diederik Gommers, Michel E. van Genderen
Summary: This study aimed to investigate the effects of ICU-VR on mental health and ICU aftercare in COVID-19 ICU survivors. The results showed that ICU-VR improved satisfaction with and rating of ICU aftercare, but had limited impact on psychological recovery and quality of life.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Critical Care Medicine
William D. Schweickert, Julianne Jablonski, Brian Bayes, Marzana Chowdhury, Casey Whitman, Jenny Tian, Bryan Blette, Teresa Tran, Scott D. Halpern
Summary: This study evaluated a low-cost, multifaceted mobilization intervention and found that it did not improve overall mobility but improved patients' odds of standing and was safe.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2023)
Article
Critical Care Medicine
Yaseen M. Arabi, Anthony C. Gordon, Lennie P. G. Derde, Alistair D. Nichol, Srinivas Murthy, Farah Al Beidh, Djillali Annane, Lolowa Al Swaidan, Abi Beane, Richard Beasley, Lindsay R. Berry, Zahra Bhimani, Marc J. M. Bonten, Charlotte A. Bradbury, Frank M. Brunkhorst, Meredith Buxton, Adrian Buzgau, Allen Cheng, Menno De Jong, Michelle A. Detry, Eamon J. Duffy, Lise J. Estcourt, Mark Fitzgerald, Rob Fowler, Timothy D. Girard, Ewan C. Goligher, Herman Goossens, Rashan Haniffa, Alisa M. Higgins, Thomas E. Hills, Christopher M. Horvat, David T. Huang, Andrew J. King, Francois Lamontagne, Patrick R. Lawler, Roger Lewis, Kelsey Linstrum, Edward Litton, Elizabeth Lorenzi, Salim Malakouti, Daniel F. McAuley, Anna McGlothlin, Shay Mcguinness, Bryan J. McVerry, Stephanie K. Montgomery, Susan C. Morpeth, Paul R. Mouncey, Katrina Orr, Rachael Parke, Jane C. Parker, Asad E. Patanwala, Kathryn M. Rowan, Marlene S. Santos, Christina T. Saunders, Christopher W. Seymour, Manu Shankar-Hari, Steven Y. C. Tong, Alexis F. Turgeon, Anne M. Turner, Frank Leo Van de Veerdonk, Ryan Zarychanski, Cameron Green, Scott Berry, John C. Marshall, Colin McArthur, Derek C. Angus, Steven A. Webb
Summary: Among critically ill patients with COVID-19, lopinavir-ritonavir, hydroxychloroquine, or combination therapy worsened outcomes compared to no antiviral therapy.
INTENSIVE CARE MEDICINE
(2021)
Article
Medicine, General & Internal
Ting Yang, Muhammad Saqib Mudabbar, Tao Chen, Hong Jia, Qiang Fu, Bin Liu
Summary: This study aimed to find the optimal dosage of dexmedetomidine in spinal orthopedic scoliosis correction surgery when used in combination with propofol and remifentanil. The results showed that doses of 0.2 to 0.3 μg/(kg·h) resulted in shorter wake-up time and fewer hemodynamic fluctuations compared to the dose of 0.4 μg/(kg·h).
Article
Critical Care Medicine
Yahya Shehabi, Ary Serpa Neto, Rinaldo Bellomo, Belinda D. Howe, Yaseen M. Arabi, Michael Bailey, Frances E. Bass, Suhaini Bin Kadiman, Colin J. McArthur, Michael C. Reade, Ian M. Seppelt, Jukka Takala, Matt P. Wise, Steve A. Webb
Summary: The study aimed to evaluate the association between different infusion rates of dexmedetomidine and propofol in combination and mortality, taking age into account. The results showed that increasing the dose of propofol was associated with decreased mortality in patients aged 65 years or below, while increasing the dose of dexmedetomidine may be associated with increased mortality.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2023)
Article
Critical Care Medicine
Lu Ke, Jiajia Lin, Gordon S. Doig, Arthur R. H. van Zanten, Yang Wang, Juan Xing, Zhongheng Zhang, Tao Chen, Lixin Zhou, Dongpo Jiang, Qindong Shi, Jiandong Lin, Jun Liu, Aibin Cheng, Yafeng Liang, Peiyang Gao, Junli Sun, Wenming Liu, Zhenyu Yang, Rumin Zhang, Wei Xing, An Zhang, Zhigang Zhou, Tingfa Zhou, Yang Liu, Fei Tong, Qiuhui Wang, Aijun Pan, Xiaobo Huang, Chuming Fan, Weihua Lu, Dongwu Shi, Lei Wang, Wei Li, Liming Gu, Yingguang Xie, Rongqing Sun, Feng Guo, Lin Han, Lihua Zhou, Xiangde Zheng, Feng Shan, Jianbo Liu, Yuhang Ai, Yan Qu, Liandi Li, Hailing Li, Zhiguo Pan, Donglin Xu, Zhiqiang Zou, Yan Gao, Chunli Yang, Qiuye Kou, Xijing Zhang, Jinglan Wu, Chuanyun Qian, Weixing Zhang, Minjie Zhang, Yuan Zong, Bingyu Qin, Fusen Zhang, Zhe Zhai, Yun Sun, Ping Chang, Bo Yu, Min Yu, Shiying Yuan, Yijun Deng, Liyun Zhao, Bin Zang, Yuanfei Li, Fachun Zhou, Xiaomei Chen, Min Shao, Weidong Wu, Ming Wu, Zhaohui Zhang, Yimin Li, Qiang Guo, Zhiyong Wang, Yuanqi Gong, Yunlin Song, Kejian Qian, Yongjian Feng, Baocai Fu, Xueyan Liu, Zhiping Li, Chuanyong Gong, Cheng Sun, Jian Yu, Zhongzhi Tang, Linxi Huang, Biao Ma, Zhijie He, Qingshan Zhou, Rongguo Yu, Zhihui Tong, Weiqin Li
Summary: This large-scale multicenter trial found that active implementation of an evidence-based feeding guideline reduced the time to commencement of enteral nutrition and overall parenteral nutrition use, but did not result in a reduction in mortality among critically ill patients.
Article
Critical Care Medicine
Yuetian Yu, Cheng Zhu, Yucai Hong, Lin Chen, Zhiping Huang, Jiancang Zhou, Xin Tian, Dadong Liu, Bo Ren, Cao Zhang, Caibao Hu, Xinan Wang, Rui Yin, Yuan Gao, Zhongheng Zhang
Summary: In a multicentre, open-label trial, adults with septic shock were randomly assigned to receive usual care or anisodamine. There was no significant difference in hospital mortality or ventilator-free days between the usual care and anisodamine groups, but the treated group had significantly lower serum lactate levels and were less likely to need vasopressors.
Article
Medicine, General & Internal
Fang Zhang, Xue Mei, Ping Zhou, Ying-Ping Tian, Jin-Xiang Liu, Xu Dong, Ding-Shan Yuan, Zhao-Fen Lin, Lei Zhang, Jin-Hao Lin, Ai-Jun Li, Xing Deng, Ming-Zhi Chen, Shi-Ying Yuan, Jun-Jing Zha, Bin Shi, Zhi-Hong Lin, Shu-Bin Guo
Summary: This study aimed to investigate the therapeutic efficacy of Anisodamine hydrobromide (Ani HBr), a Chinese medicine, in the treatment of septic shock. The results showed that Ani HBr may serve as an important adjuvant to conventional treatment, reducing the 28-day mortality in patients with septic shock.
ANNALS OF MEDICINE
(2023)
Article
Nutrition & Dietetics
Kensuke Nakamura, Hidehiko Nakano, Hiromu Naraba, Masaki Mochizuki, Yuji Takahashi, Tomohiro Sonoo, Hideki Hashimoto, Naoto Morimura
Summary: In critical care, high protein delivery combined with active early rehabilitation helps to maintain muscle volume and reduce inflammation and immunosuppression.
CLINICAL NUTRITION
(2021)