Review
Medicine, General & Internal
Jiang Liu, Shirong Fang, Yuxia Wang, Lunan Gao, Tingting Xin, Yuxiu Liu
Summary: This systematic review and meta-analysis aimed to evaluate the safety and effectiveness of massage for pain management in neonates. The results showed that massage could effectively improve pain response in neonates and have positive effects on crying duration and blood oxygen saturation. However, the effects on respiratory rate and heart rate were not significant.
Article
Obstetrics & Gynecology
Sushma Reddy, Saudamini V. Nesargi, Sofia Stevens, Jiya Jose, Hindumati Babu
Summary: By implementing a series of interventions and PDCA cycles, the utilization rate of procedural analgesia was successfully increased from 11% to 40%, and ultimately stabilized at around 75%. Simple interventions can improve and sustain the utilization of procedural analgesia.
AMERICAN JOURNAL OF PERINATOLOGY
(2022)
Article
Obstetrics & Gynecology
Britney Benoit, Aaron Newman, Ruth Martin-Misener, Margot Latimer, Marsha Campbell-Yeo
Summary: The study aimed to compare the effects of breastfeeding and oral sucrose on pain-related electrophysiologic activity and behavioral responses in infants during heel lance procedures. The results showed that both interventions reduced pain responses, but breastfeeding infants had smaller pain-related potential amplitudes and faster physiological recovery compared to those who received oral sucrose. Further research is needed to understand the specific neurophysiological effects of these interventions on infant pain response.
EARLY HUMAN DEVELOPMENT
(2021)
Article
Biochemical Research Methods
Yanjie Chen, Peng Ji, Guangyin Ma, Zehua Song, Bruce Qing Tang, Tongju Li
Summary: An established HPLC method allowed simultaneous measurement of key components for studying mitochondrial functions. The study revealed the impact of Jurkat cell density on energy and oxidative states, as well as a significant correlation between UA levels in serum and saliva. These results demonstrate the method's accuracy and applicability for various biological, pharmacological, and clinical studies.
BIOMEDICAL CHROMATOGRAPHY
(2021)
Editorial Material
Urology & Nephrology
Federica Piani, Richard J. Johnson
Summary: Gout is common in patients with CKD, and those with kidney dysfunction may have hyperechoic medullas, potentially linked to increased risk of hypertension and kidney dysfunction. More research is needed to validate these findings.
KIDNEY INTERNATIONAL
(2021)
Article
Clinical Neurology
Anastasis Georgoulas, Laura Jones, Maria Pureza Laudiano-Dray, Judith Meek, Lorenzo Fabrizi, Kimberley Whitehead
Summary: In this study of 175 infants, unique regulation of sleep-wake states was observed, with particularly long durations of active sleep. Stress and nociception were found to impact sleep durations, especially in preterm infants, highlighting the importance of environmental interventions in promoting healthy sleep patterns.
Article
Chemistry, Multidisciplinary
Zheng Wei, Tanja Knaus, Yuxin Liu, Ziran Zhai, Andrea F. G. Gargano, Gadi Rothenberg, Ning Yan, Francesco G. G. Mutti
Summary: We developed a highly efficient biosensor for uric acid detection by immobilizing modified urate oxidase on gold nanoparticles deposited on a carbon-glass electrode. This biosensor exhibits a low limit of detection (9.16 nM), a high sensitivity (14 mu A/mu M), a wide linear range (50 nM-1 mM), and a long lifetime of over 28 days.
CHEMICAL COMMUNICATIONS
(2023)
Article
Clinical Neurology
Bowen Chang, Xuanzhi Wang, Peng Chen, Chen Ni, Chaoshi Niu, Haochen Guan
Summary: The study provides the first evidence of an association between serum uric acid levels and trigeminal neuralgia. Low uric acid levels are associated with an increased risk of trigeminal neuralgia and more severe clinical symptoms.
NEUROLOGICAL SCIENCES
(2022)
Article
Geriatrics & Gerontology
M. Wang, C. Wang, M. Zhao, Y. Li, S. Yao, S. Wu, H. Xue
Summary: This study found a positive correlation between UA variability and all-cause mortality in a community cohort study in northern China. The risk of all-cause death increased as UAVIM value increased. Sensitivity analysis excluding participants with hyperuricemia or severe chronic kidney diseases still showed similar results.
JOURNAL OF NUTRITION HEALTH & AGING
(2021)
Article
Multidisciplinary Sciences
Xin Ting Zheng, Zijie Yang, Laura Sutarlie, Moogaambikai Thangaveloo, Yong Yu, Nur Asinah Binte Mohamed Salleh, Jiah Shin Chin, Ze Xiong, David Lawrence Becker, Xian Jun Loh, Benjamin C. K. Tee, Xiaodi Su
Summary: This study presents a battery-free paper-based sensor that utilizes deep learning algorithms to comprehensively assess wounds, including inflammation and infection. The sensor consists of a wax-printed paper panel with five colorimetric sensors for measuring temperature, pH, trimethylamine, uric acid, and moisture. By analyzing sensor images captured by a mobile phone using neural network-based machine learning algorithms, the healing status of wounds can be determined. The sensor can accurately classify healing versus non-healing status with up to 97% accuracy in ex situ experiments using exudates collected from rat perturbed wounds and burn wounds. In situ monitoring of wound progression and severity is demonstrated by attaching the sensor patches to rat burn wound models. This PETAL sensor enables early warning of adverse events, facilitating prompt clinical intervention for wound care management.
Article
Plant Sciences
Ruixia Bao, Qian Chen, Zheng Li, Dan Wang, Yuzheng Wu, Mengyang Liu, Yi Zhang, Tao Wang
Summary: The study isolated a compound named eurycomanol from E. longifolia, which was found to promote uric acid excretion through kidney and intestine, decrease hepatic purine synthesis, and maintain uric acid homeostasis. This suggests the potential of eurycomanol to be developed as a novel drug for the treatment of under-excretion type hyperuricemia.
Article
Multidisciplinary Sciences
Xiao Lyu, Yuanxiao Du, Guoyu Liu, Tingyu Mai, You Li, Zhiyong Zhang, Chunhua Bei
Summary: The prevalence and influencing factors of hyperuricemia (HUA) in Gongcheng, southern China were investigated. Logistic regression and Bayesian network models were used to analyze the data, and it was found that fatty liver disease, dyslipidemia, abdominal obesity, creatinine, somatotype, bone mass, drinking, and physical activity level at work were associated with HUA. A good somatotype, achieved through a healthy diet and moderate exercise, can reduce the prevalence rate of HUA.
SCIENTIFIC REPORTS
(2023)
Review
Neurosciences
Francisney Pinto Nascimento, Sergio Jose Macedo-Junior, Fernanda Rocha Lapa-Costa, Fernando Cezar-dos-Santos, Adair R. S. Santos
Summary: Inosine, a naturally occurring purine nucleoside, has gained recognition in the central nervous system and is identified as a natural trigger of adenosine receptors. Research has highlighted its potential therapeutic effects in chronic pain, schizophrenia, epilepsy, depression, anxiety, as well as neural regeneration and neurodegenerative diseases.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
Xiaofen Qi, Kaifang Guan, Chunhong Liu, Haoran Chen, Ying Ma, Rongchun Wang
Summary: The combination of Pro-Glu-Trp (PEW) and Leu-Leu-Trp (LLW) has been found to alleviate hyperuricemia (HUA) and kidney injury. This is achieved by reducing uric acid levels, improving renal oxidative stress and mitochondrial damage, and modulating gut microbiota composition.
JOURNAL OF DAIRY SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Asli Neslihan Avan, Sema Demirci-Cekic, Resat Apak
Summary: Immobilization of biological enzymes using magnetic nanoparticles as support materials enables cost reduction and reusability. In this study, three different oxidase enzymes were successfully immobilized on MNPs, and colorimetric nanobiosensors were developed for the determination of biologically important substrates. The immobilized enzymes showed no loss of affinity for the substrate, and the system exhibited wide linear concentration ranges and low detection limits, with the ability to be reused multiple times.
Article
Rehabilitation
Mastour S. Alshaharani, Everett B. Lohman, Khaled Bahjri, Travis Harp, Mansoor Alameri, Hatem Jaber, Noha S. Daher
JOURNAL OF SPORT REHABILITATION
(2020)
Article
Nursing
Dorothy Forde, Douglas D. Deming, John C. Tan, Raylene M. Phillips, Eileen K. Fry-Bowers, Mary K. Barger, Khaled Bahjri, Danilyn M. Angeles, Danilo S. Boskovic
BIOLOGICAL RESEARCH FOR NURSING
(2020)
Article
Obstetrics & Gynecology
Danilyn M. Angeles, Danilo S. Boskovic, John C. Tan, Wendy Shih, Erin Hoch, Dorothy Forde, Raylene M. Phillips, Andrew Hopper, Douglas D. Deming, Mitchell Goldstein, Giang Truong, Aprille Febre, Priscilla Pegis, Adrian Lavery, Munaf Kadri, Anamika Banerji, Iman Mousselli, Vora Farha, Elba Fayard
JOURNAL OF PERINATOLOGY
(2020)
Article
Dentistry, Oral Surgery & Medicine
William A. Chen, Hansel M. Fletcher, Joseph D. Gheorghe, Udochukwu Oyoyo, Danilo S. Boskovic
MOLECULAR ORAL MICROBIOLOGY
(2020)
Article
Hematology
Soo Min Jang, Khaled Bahjri, Joanna Lee, Sanaz Nabavi, Amir Abdipour
Summary: This study aimed to determine whether the use of ACE inhibitors increases the risk of adverse drug reactions in patients undergoing therapeutic plasma exchange with a conventional centrifuge-based apheresis system. The results showed that there was no significant association between ACEi use and adverse events in these patients. More randomized controlled prospective trials may be needed for further investigation.
THERAPEUTIC APHERESIS AND DIALYSIS
(2021)
Article
Dentistry, Oral Surgery & Medicine
William A. Chen, Hansel M. Fletcher, Kimberly J. Payne, Sheryl Aka, Melanie B. Thornburg, Joseph D. Gheorghe, Shahnaj Binte Safi, David Shavlik, Udochukwu Oyoyo, Danilo S. Boskovic
Summary: The study demonstrates that P. gingivalis can enhance platelet activation, platelet interactions with neutrophils, and the level of neutrophil antimicrobial NETs.
MOLECULAR ORAL MICROBIOLOGY
(2021)
Article
Geology
Danilo S. Boskovic, Uriel L. Vidal, Kevin E. Nick, Raul Esperante, Leonard R. Brand, Kenneth R. Wright, Lawrence B. Sandberg, Bethania C. T. Siviero
Summary: Microstructural and biomolecular preservation has been observed in fossils dating back to the Triassic period. This study focused on collecting fragments of fossil whale bone from the Pisco Formation in order to analyze the presence of extractable protein. While there were discoveries of protein content in the fossils, attempts at protein identification were not successful. Despite this, the study contributes to the growing body of evidence on microstructural and organic preservation in fossils.
Article
Obstetrics & Gynecology
Danilyn M. Angeles, Danilo S. Boskovic, Douglas Deming, Andrew Hopper, Ricardo Peverini, Adam Czynski, Erin Hoch, Raylene Phillips, John B. Tan, Victor Camberos, Khaled Bahjri, Priscilla Pegis, Mitchell Goldstein, Giang Truong, Elba Fayard
Summary: This study investigated the effects of repeated administration of sucrose or dextrose on energy metabolism in premature neonates. The results showed that the impact of repeated oral sucrose on energy metabolism is unclear, while neonates receiving oral dextrose had lower levels of certain urinary markers. Larger clinical studies are needed for further comparison between sucrose and dextrose treatments.
JOURNAL OF PERINATOLOGY
(2021)
Article
Marine & Freshwater Biology
Tyler S. dos Santos, Danilo S. Boskovic, Wendy Shih, Stephen G. Dunbar
Summary: This study aims to determine if the hermit crab Pagurus samuelis can be an indicator species along the Southern California coast. The concentrations of five heavy metals were analyzed in seawater and hermit crab samples, and differences in metal concentrations were found between locations and populations.
JOURNAL OF CRUSTACEAN BIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Billy C. Wang, Richard P. Lion, Michael Avesar, Jonathan Abdala, Douglas D. Deming, Christopher G. Wilson
Summary: This study compared the local and systemic inflammatory responses of noninvasive ventilation (NIV) and invasive mechanical ventilation (IMV) in rats with lung injury and healthy rats. The results showed that NIV treatment significantly reduced pulmonary inflammation levels in the LPS-injured group, while there was no significant difference in the IMV-treated group compared to control.
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
(2022)
Review
Microbiology
William A. Chen, Yuetan Dou, Hansel M. Fletcher, Danilo S. Boskovic
Summary: P. gingivalis is a gram-negative anaerobe that causes periodontitis. It disrupts commensal interactions in the oral cavity to induce a dysbiotic, proinflammatory state. P. gingivalis avoids complete host immunosuppression to take advantage of inflammation-induced tissue damage for robust bacterial growth.
Article
Substance Abuse
Majed M. Ramadan, Jim E. Banta, Khaled Bahjri, Susanne B. Montgomery
JOURNAL OF ADDICTIVE DISEASES
(2020)
Article
Pharmacology & Pharmacy
Soo Min Jang, Khaled Bahjri, Huyentran Tran