Article
Medicine, General & Internal
Jessica Finianos, Elisabet Sanchez-Rodriguez, Pere J. Ferrando, Jordi Miro
Summary: This study translated the 0-10 Numerical Rating Scale (NRS-11) into Arabic and examined its dimensionality, construct validity, and reliability. The results showed that the NRS-11-Arabic and VAS-Arabic scores measure the same construct, supporting its construct validity. The correlations between NRS-11-Arabic and PCS-Arabic were lower, indicating discriminant validity. Test-retest reliability was high, indicating the reliability of the NRS-11-Arabic scores. These findings provide preliminary evidence for the use of NRS-11-Arabic in clinical and research activities involving Arabic-speaking pediatric samples.
CURRENT MEDICAL RESEARCH AND OPINION
(2022)
Article
Pediatrics
Jingjing Lv, Jianwei Zhang, Kan Zhang, Jijian Zheng
Summary: This study demonstrates that PTI, obtained at the end of surgery, can be used to predict acute postoperative pain in children. This helps with early recognition and treatment of postoperative pain, reducing pain in children. Additionally, PTI shows good consistency with SPI in predicting acute postoperative pain in children.
FRONTIERS IN PEDIATRICS
(2022)
Article
Anesthesiology
Josep Roman-Juan, Ester Sole, Elisabet Sanchez-Rodriguez, Elena Castarlenas, Mark P. Jensen, Jordi Miro
Summary: The pediatric version of the GCPS-R is a valid tool for assessing chronic pain in children and adolescents. The study found that participants with bothersome chronic pain and high-impact chronic pain reported worse physical health, more anxiety and depressive symptoms, pain catastrophizing, and activity limitations compared to those with mild chronic pain.
Article
Obstetrics & Gynecology
A. Linzbach, D. Nitschke, J. Rothaug, M. Komann, C. Weinmann, E. Schleussner, W. Meissner, J. Jimenez Cruz, U. Schneider
Summary: Labor pain is a highly significant experience for women, with factors such as younger age, longer gestational age, and longer labor duration contributing to higher pain perception. Regional analgesia shows some potential in reducing pain perception. The questionnaire used in this study demonstrated good reliability and validity.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2022)
Article
Anesthesiology
Jihong Fang, Wei Wu, Jiawei Liu, Sicheng Zhang
Summary: Current automated pain assessment methods for children are limited to infants and youth, which is impractical in clinical scenarios where children of different ages suffer from postoperative pain. In this study, a large-scale Clinical Pain Expression of Children (CPEC) dataset is presented for assessing postoperative pain in children. A deep learning-based framework called Children Pain Assessment Neural Network (CPANN) is developed to automatically assess postoperative pain based on children's facial expressions. The CPANN achieves an accuracy of 82.1% and a macro-F1 score of 73.9% on the CPEC testing set, demonstrating the effectiveness of the deep learning-based method for automated pain assessment in children.
Article
Health Care Sciences & Services
Emad Kasaeyan Naeini, Ajan Subramanian, Michael-David Calderon, Kai Zheng, Nikil Dutt, Pasi Liljeberg, Sanna Salantera, Ariana M. Nelson, Amir M. Rahmani
Summary: This study aimed to develop and evaluate an automatic and adaptable pain assessment algorithm based on ECG features for assessing acute pain in postoperative patients. The results showed the feasibility of using machine learning algorithms to accurately assess acute pain among hospitalized patients.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Orthopedics
Linda Helenius, Tommi Yrjala, Hanna Oksanen, Olli Pajulo, Eliisa Loyttyniemi, Markku Taittonen, Ilkka Helenius
Summary: The study found that perioperative pregabalin did not reduce postoperative opioid consumption or the incidence of persistent postoperative pain in adolescents with spinal deformities undergoing instrumented posterior spinal fusion.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2021)
Review
Anesthesiology
Neil Singla, Timothy Rogier
Summary: To fully understand the effectiveness of an experimental analgesic in treating acute postoperative pain, it is important to evaluate its impact on both hard-tissue and soft-tissue pain. Regulatory bodies such as the FDA and EMA require drug developers to demonstrate efficacy in both areas for broad approval. While hard-tissue models have been well-established, a standardized and efficient soft-tissue model was lacking until the development of abdominoplasty in 2014. Multiple industry-sponsored studies have since confirmed the validity and usefulness of abdominoplasty as a model for assessing investigational analgesics for soft-tissue pain.
Article
Oncology
Maaret Eskelinen, Iina Saimanen, Tuomas Selander, Anu Holopainen, Esa Hamalainen, Matti Eskelinen
Summary: In patients with cholelithiasis, postoperative serum IL-18BP values are significantly correlated with pain scores and analgesic doses, indicating a potential role of IL-18BP in immune regulation of postoperative pain.
ANTICANCER RESEARCH
(2023)
Article
Pediatrics
Tommi Yrjala, Ilkka Helenius, Tiia Rissanen, Matti Ahonen, Markku Taittonen, Linda Helenius
Summary: This study found that persistent postoperative pain in adolescents undergoing posterior spinal fusion is related to disease pathology, while higher acute postoperative pain is associated with a more extensive surgery. Spondylolisthesis patients reported more chronic pain after surgery compared to adolescent idiopathic scoliosis (AIS) and Scheuermann kyphosis (SK) patients.
Article
Clinical Neurology
Lorin Stahlschmidt, Meltem Dogan, Bettina Huebner-Moehler, Kelsey Jervis, Edin T. Randall, Dustin P. Wallace, Boris Zernikow, Julia Wager
Summary: This study developed a Scale for Pain Self-Efficacy (SPaSE) in both German and English languages using a thorough development process. The SPaSE showed good psychometric properties and reliability, and its scores were negatively correlated with pain-related disability, pain intensity, passive pain coping strategies, and emotional distress, aligning with previous research. The SPaSE can be used in clinical practice and research to monitor pain treatment progress and outcome in children and adolescents.
Article
Nursing
Manuel Luque Oliveros, Ruben Morilla Romero de la Osa
Summary: The study evaluated the effectiveness of wound infiltration with 0.5% bupivacaine for pain management in cardiac surgery patients. Results showed a significant difference in pain scores between the bupivacaine and saline infiltration groups, with bupivacaine providing clinically and statistically significant pain relief in the immediate post-operative period.
NURSING IN CRITICAL CARE
(2022)
Article
Medicine, General & Internal
Wubet Dessie Amberbir, Samuel Debas Bayable, Melaku Bantie Fetene
Summary: This study aimed to determine the prevalence and factors associated with acute postoperative pain. The pain was measured through a numerical rating scale at 2, 12, and 24 hours postoperatively, and it was found that 73.1% of patients experienced at least one episode of moderate to severe postoperative pain within the first 24 hours. Preoperative anxiety, urban residency, lack of formal education, absence of pre-emptive analgesia, abdominal incision greater than 10 cm, and surgical duration greater than or equal to 60 min were factors associated with acute postoperative pain following elective gynecologic surgery. The study concluded that the incidence of moderate to severe postoperative pain after gynecologic surgery was unacceptably high.
ANNALS OF MEDICINE AND SURGERY
(2023)
Article
Clinical Neurology
Mohamed Macki, Travis Hamilton, Lara Massie, Michael Bazydlo, Lonni Schultz, Donald Seyfried, Paul Park, Ilyas Aleem, Muwaffak Abdulhak, Victor W. Chang, Jason M. Schwalb
Summary: The study aimed to determine the outcome of surgery (decompression only vs. fusion) for pure axial back pain without leg pain. The results showed that only the severity of preoperative back pain was associated with improvement in back pain at all time points. Surgery should be considered for selected patients with severe axial pain without leg pain.
Article
Health Care Sciences & Services
Vanessa A. Olbrecht, Keith T. O'Conor, Sara E. Williams, Chloe O. Boehmer, Gilbert W. Marchant, Susan M. Glynn, Kristie J. Geisler, Lili Ding, Gang Yang, Christopher D. King
Summary: The study aimed to assess the impact of a single guided relaxation-based virtual reality (VR-GR) session on postoperative pain and anxiety reduction in children. The results showed that this method can temporarily reduce pain intensity, pain unpleasantness, and anxiety, with better effects in patients with higher anxiety sensitivity scores.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Editorial Material
Anesthesiology
M. Gabrielle Page, Karim S. Ladha
ANESTHESIA AND ANALGESIA
(2022)
Article
Health Care Sciences & Services
Lise Dassieu, Emilie Paul-Savoie, Elise Develay, Ana Cecilia Villela Guilhon, Anais Lacasse, Line Guenette, Kadija Perreault, Helene Beaudry, Laurent Dupuis
Summary: This study aimed to understand experiences of people living with chronic pain and community pharmacists regarding the management of analgesic adverse effects. Patients and pharmacists had varying definitions of adverse effects, leading to dilemmas and discrepancies in decision-making. Pharmacists faced barriers in supporting patients due to organizational and financial constraints.
HEALTH EXPECTATIONS
(2022)
Article
Education, Scientific Disciplines
M. Gabrielle Page, Elise Develay, Paul Simard, Jocelyne Parent, Nicole Tremblay, Aline Boulanger
Summary: This study aims to explore the factors influencing the uptake of a continuous education program for chronic pain. The study identified five factors that facilitated engagement and participation in the program, including rapid access to reliable information, appraising one's knowledge, cultivating meaningful relationships, breaking the silos of learning and practice, and opportunities for treatment orchestrations. However, obstacles such as the heterogeneity of participants' profiles, feelings of powerlessness and discouragement, challenges in applying recommendations, medical hierarchy, and missed opportunities for advocacy were also identified.
JOURNAL OF CONTINUING EDUCATION IN THE HEALTH PROFESSIONS
(2022)
Article
Clinical Neurology
Peter Stilwell, Anne Hudon, Keith Meldrum, M. Gabrielle Page, Timothy H. Wideman
Summary: Suffering plays a central role in pain research, but the construct of pain-related suffering has not been operationalized. This article presents key attributes of pain-related suffering and discusses the challenges associated with the conceptualization by Cassell.
Article
Clinical Neurology
M. Gabrielle Page, Lise Gauvin, Marie-Pierre Sylvestre, Roy Nitulescu, Alina Dyachenko, Manon Choiniere
Summary: This ecological momentary assessment study found that pain intensity fluctuates among individuals with chronic low back pain, but the factors influencing this variability remain unclear.
Article
Psychiatry
Megan A. Kirk, Bilal Taha, Kevin Dang, Hugh McCague, Dimitrios Hatzinakos, Joel Katz, Paul Ritvo
Summary: This study investigated the effectiveness of a web-based cognitive behavioral therapy, mindfulness, and yoga program for individuals with PTSD symptoms. The results showed significant improvements in PTSD severity, depression, anxiety, and mindfulness. Additionally, psychophysiological outcomes indicated a significant reduction in peak pupil dilation (PPD) but no significant change in heart rate variability (HRV). Participants spent an average of 11.53 minutes per day on self-directed mindfulness practice.
JMIR MENTAL HEALTH
(2022)
Article
Pediatrics
Larah Maunder, Maria Pavlova, Jaimie K. Beveridge, Joel Katz, Tim Salomons, Melanie Noel
Summary: The bidirectional relationship between anxiety and pediatric chronic pain may be maintained by sensitivity to pain traumatization. High anxiety youth with high sensitivity to pain traumatization are more likely to report higher pain intensity three months later.
Article
Health Care Sciences & Services
Paul Ritvo, David Gratzer, Yuliya Knyahnytska, Abigail Ortiz, Clarice Walters, Joel Katz, Judith Laposa, Christopher Baldissera, Noah Wayne, Donna Pfefer-Litman, George Tomlinson, Zafiris Daskalakis
Summary: This study aims to assess the efficacy and noninferiority of online group CBT-M treatment in major depressive disorder, compared to in-person CBT-M. It also evaluates the cost-effectiveness of both interventions and examines whether digitally recorded data can predict depression symptom reduction in online participants.
JMIR RESEARCH PROTOCOLS
(2022)
Correction
Health Care Sciences & Services
Paul Ritvo, David Gratzer, Yuliya Knyahnytska, Abigail Ortiz, Clarice Walters, Joel Katz, Judith Laposa, Christopher Baldissera, Noah Wayne, Donna Pfefer-Litman, George Tomlinson, Zafiris Daskalakis
JMIR RESEARCH PROTOCOLS
(2022)
Review
Clinical Neurology
Sandra J. Drozdz, Akash Goel, Matthew W. McGarr, Joel Katz, Paul Ritvo, Gabriella F. Mattina, Venkat Bhat, Calvin Diep, Karim S. Ladha
Summary: Ketamine-assisted psychotherapy (KAP) can significantly reduce pain, anxiety, and depressive symptoms in patients, and can encourage treatment engagement and abstinence. However, further research is needed to understand the relationship between psychotherapy and ketamine and optimize long-term effectiveness.
JOURNAL OF PAIN RESEARCH
(2022)
Article
Clinical Neurology
Fiona Webster, Laura Connoy, Abhimanyu Sud, Kathleen Rice, Joel Katz, Andrew D. Pinto, Ross Upshur, Craig Dale
Summary: There have been recent calls to re-think chronic pain in response to social inequities. Many clinically oriented accounts lack critical theoretical understanding. To truly rethink pain, we must also reconsider suffering and listen to the experiences of people with chronic pain.
Editorial Material
Clinical Neurology
Tonya M. Palermo, Karen Deborah Davis, Didier Bouhassira, Robert W. Hurley, Joel D. Katz, Francis J. Keefe, Michael Schatman, Dennis C. Turk, David Yarnitsky
Article
Communication
Rebecca E. Lewinson, Jeffrey D. Wardell, Naama Kronstein, Karli K. Rapinda, Tyler Kempe, Joel Katz, Hyoun S. Kim, Matthew T. Keough
Summary: Early in the COVID-19 pandemic, some individuals turned to video games to cope with isolation and negative emotions caused by physical distancing guidelines. A longitudinal study with Canadian gamers showed that high initial levels of emotional vulnerability (anxiety and depression) predicted excessive time spent gaming and related problems six months later. These associations were mediated by elevated coping motives for gaming. This study highlights the importance of finding effective ways of coping for individuals who struggle with mood and anxiety issues during the pandemic.
CYBERPSYCHOLOGY-JOURNAL OF PSYCHOSOCIAL RESEARCH ON CYBERSPACE
(2023)
Review
Medicine, General & Internal
Marimee Godbout-Parent, Tristan Spilak, M. Gabrielle Page, Manon Choiniere, Lise Dassieu, Gwenaelle De Clifford-Faugere, Anais Lacasse
Summary: The COVID-19 pandemic has had significant consequences for individuals with chronic pain, exacerbating pre-existing burdens and treatment gaps. However, it has also led to the development of concrete recommendations to improve healthcare and chronic pain management during the pandemic. These recommendations cover a wide range of areas, including changes in clinical practice and policy, continuity of care, virtual care, infection control, lifestyle modifications, and non-pharmacological and pharmacological treatments.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Surgery
Marguerite Mainprize, Ayse Yilbas, Fernando A. C. Spencer Netto, Anton Svendrovski, Joel Katz
Summary: The study examined opioid use, pain intensity, and pain management following primary unilateral inguinal hernia repair (PUIHR) at a specialty hospital. Most participants did not require opioids for pain control post-surgery, and had lower mean NRS pain intensity scores compared to those who did. Opioids were discontinued by day 3 for all participants who received them, demonstrating effective pain control with nonopioid multimodal analgesia for most patients undergoing PUIHR.
LANGENBECKS ARCHIVES OF SURGERY
(2023)