Article
Radiology, Nuclear Medicine & Medical Imaging
Ming Ni, Xiaoyi Wen, Mengze Zhang, Chenyu Jiang, Yali Li, Ben Wang, Xianchang Zhang, Qiang Zhao, Ning Lang, Liang Jiang, Huishu Yuan
Summary: This study explored the preoperative dMRI parameters to predict the postoperative outcome of CSM through multifactor correlation analysis. The FA value based on dMRI significantly positively correlated with CSM patient postoperative outcomes, helping to predict the surgical outcome and formulate a treatment plan before surgery.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Article
Clinical Neurology
Adam Y. Li, Lily McCarthy, Eugene Hrabarchuk, Zachary Spiera, Naoum Fares Marayati, Alexander J. Schupper, Theodore C. Hannah, Lisa Genadry, Muhammad Ali, Addison Quinones, Roshini Kalagara, Rebecca Baron, Panagiotis Sideras, Thomas P. Naidich, Tanvir F. Choudhri
Summary: This study evaluated the severity of cervical spondylotic myelopathy using quantitative and subjective grading scales in dynamic sagittal MRI as well as static axial and sagittal images. The results showed that flexion-extension MRI can detect cervical pathology that is not detectable on conventional static MRI. The subjective grading scales for assessing degenerative changes were found to be more severe in patients requiring surgical intervention.
WORLD NEUROSURGERY
(2023)
Article
Clinical Neurology
Fabio Pilato, Rosalinda Calandrelli, Marisa Distefano, Francesco Ciro Tamburrelli
Summary: This study developed a comprehensive score system (CSS) that considers clinical, neurophysiological, and neuroradiological data to predict outcome in patients with cervical spondylotic myelopathy undergoing surgery. The CSS model showed good accuracy in predicting outcomes and supporting surgeons' decisions for surgery candidates.
NEUROLOGICAL SCIENCES
(2021)
Article
Orthopedics
Wook-Tae Park, Woo-Kie Min, Ji-Hoon Shin, Sang-Bong Ko, Eun-Seok Son, Jiyoun Kim, Jihoon Jang, Gun Woo Lee
Summary: This study aimed to assess the reliability and accuracy of dynamic magnetic resonance imaging in detecting cervical spondylotic myelopathy (CSM). The results indicated that dynamic MR showed better diagnostic reliability and accuracy compared to conventional MR, with extension MR scans providing a more accurate diagnosis than other images.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Review
Medicine, General & Internal
Ali Fahim Khan, Grace Haynes, Esmaeil Mohammadi, Fauziyya Muhammad, Sanaa Hameed, Zachary A. A. Smith
Summary: Cervical spondylotic myelopathy (CSM) is a progressive disease that can worsen over time. Early diagnosis and prompt treatment can slow down the progression and improve symptoms. Magnetic resonance imaging (MRI) methods have been increasingly used in diagnosing and managing CSM, providing detailed images and data on tissue injury. However, there are challenges hindering the clinical utility of these neuroimaging methods.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Critical Care Medicine
Tomas Horak, Magda Horakova, Alena Svatkova, Zdenek Kadanka, Petr Kudlicka, Jan Valosek, Tomas Rohan, Milos Kerkovsky, Eva Vlckova, Zdenek Kadanka, Dinesh K. Deelchand, Pierre-Gilles Henry, Josef Bednarik, Petr Bednarik
Summary: This study utilized proton magnetic resonance spectroscopy to reveal progressive neurochemical alterations in non-myelopathic stage (NMDC) and degenerative cervical myelopathy (DCM). The findings showed changes in neurochemical ratios and volumes in DCM patients, suggesting that MRS can detect neurochemical changes before the onset of myelopathy symptoms, while volumetry only reflects clinically manifest myelopathy.
JOURNAL OF NEUROTRAUMA
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Julien Galley, Reto Sutter, Christoph Germann, Florian Wanivenhaus, Daniel Nanz
Summary: Non-invasive 3D-DESS MR-imaging at 3 and 7 T successfully visualizes the cervical nerve roots within the spinal canal and has the potential to provide precise assessments of their micro-anatomy. Interobserver agreement was substantial to almost perfect, and the ICC for the number of identified rootlets was 0.80.
EUROPEAN RADIOLOGY
(2021)
Article
Clinical Neurology
Kevin M. Koch, Andrew S. Nencka, Andrew Klein, Marjorie Wang, Shekar Kurpad, Aditya Vedantam, Matthew Budde
Summary: This study investigated tissue diffusion properties in the spinal cord of patients treated for CSM using post-decompression stabilization hardware. The findings showed that ADC measures in the spinal cord were globally reduced in CSM subjects compared to control subjects. Instrumented levels in CSM subjects exhibited significantly lower diffusivity than the control group.
FRONTIERS IN NEUROLOGY
(2023)
Article
Clinical Neurology
Allan R. Martin, Lindsay Tetreault, Aria Nouri, Armin Curt, Patrick Freund, Vafa Rahimi-Movaghar, Jefferson R. Wilson, Michael G. Fehlings, Brian K. Kwon, James S. Harrop, Benjamin M. Davies, Mark R. N. Kotter, James D. Guest, Bizhan Aarabi, Shekar N. Kurpad
Summary: This narrative review summarizes the role of imaging and electrophysiology techniques in the management of degenerative cervical myelopathy (DCM) and discusses the potential of emerging methods. Currently, clinical management relies on anatomical MRI, but novel quantitative assessments have the potential to transform clinical practice.
GLOBAL SPINE JOURNAL
(2022)
Article
Clinical Neurology
Allan R. Martin, Lindsay Tetreault, Benjamin M. Davies, Armin Curt, Patrick Freund, Vafa Rahimi-Movaghar, Jefferson R. Wilson, Michael G. Fehlings, Brian K. Kwon, James S. Harrop, Benjamin M. Davies, Mark R. N. Kotter, James D. Guest, Bizhan Aarabi, Shekar N. Kurpad
Summary: The study provides an overview of current imaging and electrophysiology techniques for the management of degenerative cervical myelopathy, emphasizing the key role of anatomical MRI in surgical planning. It also discusses the potential of novel quantitative assessments to transform clinical practice by more accurately reflecting changes in spinal cord microstructure and function.
GLOBAL SPINE JOURNAL
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Chanyuan Liu, Jingyi Wang, Bowen Hou, Yitong Li, John N. Morelli, Peisen Zhang, Jun Ran, Xiaoming Li
Summary: This study aimed to investigate the diurnal variation in cervical disc hydration and its relationship with cervical degeneration. The results show that cervical disc hydration significantly decreases after daytime load, and degenerative discs have lower T2 values and diurnal variation compared to healthy discs. The study also found that cervical sagittal alignment affects the diurnal stress patterns of the discs.
KOREAN JOURNAL OF RADIOLOGY
(2022)
Article
Veterinary Sciences
Kayla M. Fowler, Timothy A. Bolton, John H. Rossmeisl, Avril U. Arendse, Karen M. Vernau, Ronald H. L. Li, Rell L. Parker
Summary: This case series provides information on clinical signs, MRI findings, and outcome in 3 juvenile dogs with hemophilia A that developed neurologic deficits or paraspinal hyperesthesia secondary to spontaneous or iatrogenic vertebral canal hemorrhage. Hemophilia A should be considered as a differential in any young dog presenting with an acute onset of hyperesthesia with or without neurologic deficits. This diagnosis should be prioritized in young male dogs that have other evidence of hemorrhage on physical exam.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Physiology
Qiufeng Liu, Haoyue Shao, Chaoxu Liu, Weiyin Vivian Liu, Azzam Saeed, Qiya Zhang, Jun Lu, Guiling Zhang, Li Li, Xiangyu Tang, Guanghui Du, Wenzhen Zhu
Summary: This study aimed to investigate the feasibility and diagnostic value of synthetic MRI in determining the severity of cervical spondylotic myelopathy (CSM). The results showed that synthetic MRI can provide multiple contrast images and quantitative mapping, which showed promisingly to be a reliable and efficient method in the quantitative diagnosis of CSM.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Pharmacology & Pharmacy
T. Nguyen-Van, G. -D. Hoang, B. -T. Nguyen-Le, T. Ngo-Van, D. -T. Le, X. -T. Dao, M. -D. Nguyen
Summary: This study investigated the factors that influence surgical outcomes among patients with multilevel cervical spondylotic myelopathy (M-CSM). The study found that patients older than 60 years, male patients, and smokers had lower preoperative scores. Patients with symptoms duration longer than 6 months had lower recovery rates. Patients with intramedullary hyperintensity in s2 vertebra and anterior surgery had better postoperative recovery rates. A shorter period of hyperintensity in the intramedullary region on sagittal T2-weighted MRI was associated with faster discharge. Patients with discrete hyperintensity in the intramedullary region on axial T2-weighted MRI had a higher chance of experiencing less than 50% postoperative recovery.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2022)
Article
Clinical Neurology
Marc Hohenhaus, Jan-Helge Klingler, Christoph Scholz, Florian Volz, Ulrich Hubbe, Juergen Beck, Marco Reisert, Urs Wuertemberger, Nico Kremers, Katharina Wolf
Summary: This study aimed to quantitatively analyze the T2 signal intensity of the spinal cord in degenerative cervical myelopathy (DCM) patients using high-resolution MRI segmentation. The results showed significantly increased signal variability in DCM patients compared to healthy volunteers, and the new analysis method demonstrated sufficient diagnostic accuracy.