Load transfer, damage, and failure in ligaments and tendons

Three dimensional microstructural network of elastin, collagen, and cells in Achilles tendons

(2017) Xin Pang et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Planar biaxial extension of the lumbar facet capsular ligament reveals significant in-plane shear forces

(2017) Amy A. Claeson et al.   Journal of the Mechanical Behavior of Biomedical Materials

Molecular level detection and localization of mechanical damage in collagen enabled by collagen hybridizing peptides

(2017) Jared L. Zitnay et al.   Nature Communications

Novel Model of Tendon Regeneration Reveals Distinct Cell Mechanisms Underlying Regenerative and Fibrotic Tendon Healing

(2017) Kristen Howell et al.   Scientific Reports

Fascicles and the interfascicular matrix show adaptation for fatigue resistance in energy storing tendons

(2016) Chavaunne T. Thorpe et al.   Acta Biomaterialia

Collagen fibrils in functionally distinct tendons have differing structural responses to tendon rupture and fatigue loading

(2016) Tyler W. Herod et al.   Acta Biomaterialia

Nomenclature of the tendon hierarchy: An overview of inconsistent terminology and a proposed size-based naming scheme with terminology for multi-muscle tendons

(2016) Geoffrey G. Handsfield et al.   JOURNAL OF BIOMECHANICS

Multiscale mechanical integrity of human supraspinatus tendon in shear after elastin depletion

(2016) Fei Fang et al.   Journal of the Mechanical Behavior of Biomedical Materials

Microstructural heterogeneity directs micromechanics and mechanobiology in native and engineered fibrocartilage

(2016) Woojin M. Han et al.   NATURE MATERIALS

Elastin governs the mechanical response of medial collateral ligament under shear and transverse tensile loading

(2015) Heath B. Henninger et al.   Acta Biomaterialia

Biology and mechano-response of tendon cells: Progress overview and perspectives

(2015) Hui B. Sun et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Tendon mechanobiology:Current knowledge and future research opportunities

(2015) Michael Lavagnino et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Influence of cross-link structure, density and mechanical properties in the mesoscale deformation mechanisms of collagen fibrils

(2015) Baptiste Depalle et al.   Journal of the Mechanical Behavior of Biomedical Materials

Tension tests on mammalian collagen fibrils

(2015) Yehe Liu et al.   Interface Focus

Quantification of Interfibrillar Shear Stress in Aligned Soft Collagenous Tissues via Notch Tension Testing

(2015) Spencer E. Szczesny et al.   Scientific Reports

Low tendon stiffness and abnormal ultrastructure distinguish classic Ehlers-Danlos syndrome from benign joint hypermobility syndrome in patients

(2014) Rie Harboe Nielsen et al.   FASEB JOURNAL

Different regions of bovine deep digital flexor tendon exhibit distinct elastic, but not viscous, mechanical properties under both compression and shear loading

(2014) Fei Fang et al.   JOURNAL OF BIOMECHANICS

Temporal effect of in vivo tendon fatigue loading on the apoptotic response explained in the context of number of fatigue loading cycles and initial damage parameters

(2014) Nelly Andarawis-Puri et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Early stage fatigue damage occurs in bovine tendon fascicles in the absence of changes in mechanics at either the gross or micro-structural level

(2014) Jennifer H. Shepherd et al.   Journal of the Mechanical Behavior of Biomedical Materials

Treatment of acute ankle ligament injuries: a systematic review

(2013) Wolf Petersen et al.   ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY

Macro- to Microscale Strain Transfer in Fibrous Tissues is Heterogeneous and Tissue-Specific

(2013) Woojin M. Han et al.   BIOPHYSICAL JOURNAL

Fracture Mechanics of Collagen Fibrils: Influence of Natural Cross-Links

(2013) Rene B. Svensson et al.   BIOPHYSICAL JOURNAL

Elastic fibres are broadly distributed in tendon and highly localized around tenocytes

(2013) Tyler M. Grant et al.   JOURNAL OF ANATOMY

Effect of elastin digestion on the quasi-static tensile response of medial collateral ligament

(2013) Heath B. Henninger et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Mechanically overloading collagen fibrils uncoils collagen molecules, placing them in a stable, denatured state

(2013) Samuel P. Veres et al.   MATRIX BIOLOGY

Functionally distinct tendon fascicles exhibit different creep and stress relaxation behaviour

(2013) Jennifer H Shepherd et al.   PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE

Changes in matrix protein biochemistry and the expression of mRNA encoding matrix proteins and metalloproteinases in posterior tibialis tendinopathy

(2012) Anthony N Corps et al.   ANNALS OF THE RHEUMATIC DISEASES

Designed to Fail: A Novel Mode of Collagen Fibril Disruption and Its Relevance to Tissue Toughness

(2012) Samuel P. Veres et al.   BIOPHYSICAL JOURNAL

Repeated subrupture overload causes progression of nanoscaled discrete plasticity damage in tendon collagen fibrils

(2012) Samuel P. Veres et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Specialization of tendon mechanical properties results from interfascicular differences

(2012) C. T. Thorpe et al.   Journal of the Royal Society Interface

Microstructural stress relaxation mechanics in functionally different tendons

(2012) H.R.C. Screen et al.   MEDICAL ENGINEERING & PHYSICS

Low Stress Tendon Fatigue is a Relatively Rapid Process in the Context of Overuse Injuries

(2011) Gabriel Parent et al.   ANNALS OF BIOMEDICAL ENGINEERING

The relationships between cyclic fatigue loading, changes in initial mechanical properties, and the in vivo temporal mechanical response of the rat patellar tendon

(2011) Nelly Andarawis-Puri et al.   JOURNAL OF BIOMECHANICS

Alterations of overused supraspinatus tendon: A possible role of glycosaminoglycans and HARP/pleiotrophin in early tendon pathology

(2011) Mohamed Attia et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Hierarchical Structure and Nanomechanics of Collagen Microfibrils from the Atomistic Scale Up

(2011) Alfonso Gautieri et al.   NANO LETTERS

Molecular and structural mapping of collagen fibril interactions

(2010) J. P. R. O. Orgel et al.   CONNECTIVE TISSUE RESEARCH

Effect of sulfated glycosaminoglycan digestion on the transverse permeability of medial collateral ligament

(2010) Heath B. Henninger et al.   JOURNAL OF BIOMECHANICS

Specimen dimensions influence the measurement of material properties in tendon fascicles

(2010) Kirsten Legerlotz et al.   JOURNAL OF BIOMECHANICS

Early response to tendon fatigue damage accumulation in a novel in vivo model

(2009) David T. Fung et al.   JOURNAL OF BIOMECHANICS

In situ multi-level analysis of viscoelastic deformation mechanisms in tendon collagen

(2009) H.S. Gupta et al.   JOURNAL OF STRUCTURAL BIOLOGY

Changes in the composition of the extracellular matrix in patellar tendinopathy

(2009) Samiric Tom et al.   MATRIX BIOLOGY

Coordinate Regulation of IL-1β and MMP-13 in Rat Tendons Following Subrupture Fatigue Damage

(2008) Hui B. Sun et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Contribution of glycosaminoglycans to viscoelastic tensile behavior of human ligament

(2008) Trevor J. Lujan et al.   JOURNAL OF APPLIED PHYSIOLOGY

Mechanical overload decreases the thermal stability of collagen in an in vitro tensile overload tendon model

(2008) Thomas L. Willett et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Subrupture tendon fatigue damage

(2008) David T. Fung et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Deformation rate controls elasticity and unfolding pathway of single tropocollagen molecules

(2008) Alfonso Gautieri et al.   Journal of the Mechanical Behavior of Biomedical Materials

Nanomechanics of collagen fibrils under varying cross-link densities: Atomistic and continuum studies

(2007) Markus J. Buehler   Journal of the Mechanical Behavior of Biomedical Materials