Sclerostin monoclonal antibody enhanced bone fracture healing in an open osteotomy model in rats

Augmentation of autologous bone graft by a combination of bone morphogenic protein and bisphosphonate increased both callus volume and strength

(2013) Per Bosemark et al.   Acta Orthopaedica

Investigating the synergistic efficacy of BMP-7 and zoledronate on bone allografts using an open rat osteotomy model

(2013) Neashan Mathavan et al.   BONE

Systemic Administration of Sclerostin Antibody Enhances Bone Repair in a Critical-Sized Femoral Defect in a Rat Model

(2013) Mandeep S. Virk et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

HIF-1α Inhibits Wnt Signaling Pathway by Activating Sost Expression in Osteoblasts

(2013) Dafu Chen et al.   PLoS One

Extracorporeal Shockwave Therapy for Treatment of Delayed Tendon-Bone Insertion Healing in a Rabbit Model

(2012) Dick Ho Kiu Chow et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Osteoblast-specific transcription factor Osterix (Osx) and HIF-1α cooperatively regulate gene expression of vascular endothelial growth factor (VEGF)

(2012) Dafu Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sclerostin and Dickkopf-1 as Therapeutic Targets in Bone Diseases

(2012) Hua Zhu Ke et al.   ENDOCRINE REVIEWS

Sclerostin antibody treatment improves bone mass, bone strength, and bone defect regeneration in rats with type 2 diabetes mellitus

(2012) Christine Hamann et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Inhibition of sclerostin by systemic treatment with sclerostin antibody enhances healing of proximal tibial defects in ovariectomized rats

(2012) Michelle M. McDonald et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Effects of sclerostin antibody on healing of a non-critical size femoral bone defect

(2012) Muhammad U. Jawad et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Synergistic Inhibition of Wnt Pathway by HIF-1α and Osteoblast-Specific Transcription Factor Osterix (Osx) in Osteoblasts

(2012) Dafu Chen et al.   PLoS One

Wnt signaling and orthopedics, an overview

(2011) Fredrik Agholme et al.   Acta Orthopaedica

Angiogenesis in bone regeneration

(2011) Kurt D. Hankenson et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

The biology of fracture healing

(2011) Richard Marsell et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Transcriptional Regulation of Vascular Endothelial Growth Factor (VEGF) by Osteoblast-specific Transcription Factor Osterix (Osx) in Osteoblasts

(2011) Wanjin Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deletion of estrogen receptor beta accelerates early stage of bone healing in a mouse osteotomy model

(2011) Y.-X. He et al.   OSTEOPOROSIS INTERNATIONAL

Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody

(2010) Desmond Padhi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of nonfractured bones

(2010) Michael S Ominsky et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Low-magnitude high-frequency vibration treatment augments fracture healing in ovariectomy-induced osteoporotic bone

(2009) Hong-Fei Shi et al.   BONE

Intermittent PTH(1–34) does not increase union rates in open rat femoral fractures and exhibits attenuated anabolic effects compared to closed fractures

(2009) Magnus Tägil et al.   BONE

Increased skeletal VEGF enhances β-catenin activity and results in excessively ossified bones

(2009) Christa Maes et al.   EMBO JOURNAL

Parathyroid hormone (PTH)–induced bone gain is blunted in SOST overexpressing and deficient mice

(2009) Ina Kramer et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Wnt/Frizzled signaling in angiogenesis

(2008) Marielba Zerlin et al.   ANGIOGENESIS

Characterization of a rat osteotomy model with impaired healing

(2008) Christine Kratzel et al.   BMC MUSCULOSKELETAL DISORDERS

Bone Formation During Distraction Osteogenesis Is Dependent on Both VEGFR1 and VEGFR2 Signaling

(2008) Kimberly A Jacobsen et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone Strength

(2008) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength in a Rat Model of Postmenopausal Osteoporosis*

(2008) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Skeletal Cell Fate Decisions Within Periosteum and Bone Marrow During Bone Regeneration

(2008) Céline Colnot   JOURNAL OF BONE AND MINERAL RESEARCH

Inhibition of Wnt signaling by the osteoblast-specific transcription factor Osterix

(2008) C. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA