Lead induces an osteoarthritis-like phenotype in articular chondrocytes through disruption of TGF-β signaling

The relationship between fibrogenic TGFβ1 signaling in the joint and cartilage degradation in post-injury osteoarthritis

(2011) A. Plaas et al.   OSTEOARTHRITIS AND CARTILAGE

Aberrant hypertrophy in Smad3-deficient murine chondrocytes is rescued by restoring transforming growth factor β-activated kinase 1/activating transcription factor 2 signaling: A potential clinical implication for osteoarthritis

(2010) Tian-Fang Li et al.   ARTHRITIS AND RHEUMATISM

Central nervous system cytokine gene expression: Modulation by lead

(2010) Jane Kasten-Jolly et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Endoglin differentially regulates TGF-β-induced Smad2/3 and Smad1/5 signalling and its expression correlates with extracellular matrix production and cellular differentiation state in human chondrocytes

(2010) K.W. Finnson et al.   OSTEOARTHRITIS AND CARTILAGE

Improving Chondrogenesis: Potential and Limitations of SOX9 Gene Transfer and Mechanical Stimulation for Cartilage Tissue Engineering

(2010) Laszlo Kupcsik et al.   TISSUE ENGINEERING PART A

Increase in ALK1/ALK5 Ratio as a Cause for Elevated MMP-13 Expression in Osteoarthritis in Humans and Mice

(2009) E. N. Blaney Davidson et al.   JOURNAL OF IMMUNOLOGY

Association of cumulative lead and neurocognitive function in an occupational cohort.

(2009) Naila Khalil et al.   NEUROPSYCHOLOGY

Induction of an osteoarthritis-like phenotype and degradation of phosphorylated Smad3 by Smurf2 in transgenic mice

(2008) Qiuqian Wu et al.   ARTHRITIS AND RHEUMATISM

Smad signaling pathway is a pivotal component of tissue inhibitor of metalloproteinases-3 regulation by transforming growth factor beta in human chondrocytes

(2008) Hamid Yaqoob Qureshi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Anti-apoptotic effect of transforming growth factor-β1 on human articular chondrocytes: role of protein phosphatase 2A

(2008) M. Lires-Deán et al.   OSTEOARTHRITIS AND CARTILAGE

Activation of protein kinase Cα signaling prevents cytotoxicity and mutagenicity following lead acetate in CL3 human lung cancer cells

(2008) Chun-Yu Wang et al.   TOXICOLOGY