Journal
JOURNAL OF ORTHOPAEDIC RESEARCH
Volume 30, Issue 12, Pages 1971-1978Publisher
WILEY-BLACKWELL
DOI: 10.1002/jor.22159
Keywords
fracture healing; BB Wistar rat; vanadium; bone regeneration
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This study quantified the effects of local intramedullary delivery of an organic vanadium salt, which may act as an insulin-mimetic on fracture healing. Using a BB Wistar rat femoral fracture model, local vanadyl acetylacetonate (VAC) was delivered to the fracture site and histomorphometry, mechanical testing, and immunohistochemistry were performed. Callus percent cartilage was 200% higher at day 7 (p?
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