Article
Biochemistry & Molecular Biology
Alayna N. Hay, Khan Mohammad Imran, Alissa Hendricks-Wenger, Jessica M. Gannon, Jacqueline Sereno, Alex Simon, Victor A. Lopez, Sheryl Coutermarsh-Ott, Eli Vlaisavljevich, Irving C. Allen, Joanne L. Tuohy
Summary: This study investigated the feasibility of using histotripsy ablation as a novel noninvasive treatment option for osteosarcoma. The results showed that histotripsy can effectively ablate osteosarcoma tumors and induce local immunomodulation within the tumor microenvironment.
Article
Cell Biology
Martina Quartieri, Anggraeini Puspitasari, Tamara Vitacchio, Marco Durante, Walter Tinganelli
Summary: This study investigates the interplay between acute and chronic hypoxia and radiation exposure in selecting and characterizing cells with a Circulating Cancer Stem Cell (CCSC)-like phenotype. The results demonstrate that the combination of radiation and acute hypoxia enhances stemness, while chronic hypoxia imparts a cancer stem-like phenotype in cells.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jiaqi Li, Zhenbin Qiu, Chao Zhang, Sijie Chen, Mengmin Wang, Qiuchen Meng, Haiming Lu, Lei Wei, Hairong Lv, Wenzhao Zhong, Xuegong Zhang
Summary: Intra-tumor heterogeneity (ITH) in non-small cell lung cancer (NSCLC) can be quantified from computed tomography (CT) images, providing important insights into tumor phenotypes and patient prognosis.
EUROPEAN RADIOLOGY
(2023)
Article
Optics
Hyunwoo Lim, Hyosung Cho, Hunwoo Lee, Duhee Jeon
Summary: In this study, the quantification of dark-field effects in single-shot grid-based x-ray imaging setup was successfully achieved by measuring the real space correlation function of scattering samples. The experimental measurements were in good agreement with theoretical quantification, confirming the effectiveness of this approach for single-shot grid-based dark-field x-ray imaging. This understanding of particle-scale selectivity and suitable applications is crucial for the advancement of this technology.
Article
Chemistry, Analytical
Frank Foerste, Leona Bauer, Korbinian Heimler, Bastian Hansel, Carla Vogt, Birgit Kanngiesser, Ioanna Mantouvalou
Summary: Confocal micro-X-ray fluorescence spectroscopy is a technique that can be used for elemental imaging with 3D resolution using laboratory spectrometers. Quantification techniques are important for interpreting data and reconstructing sample composition and geometry. This article presents an analytical routine for the quantitative investigation of 3D data sets obtained with laboratory spectrometers.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2022)
Article
Chemistry, Physical
Hideaki Oka, Takamasa Nonaka, Yasuhito Kondo, Yoshinari Makimura
Summary: In this study, an electrochemical cell capable of controlled overcharging and temperature regulation is developed, and the reactions between the electrodes and the electrolyte are investigated during heated overcharging. The results show that higher temperatures during overcharging lead to increased side reactions in the positive electrode, while the negative electrode gradually increases side reactions with increasing temperature in the normal charge-discharge region. The side reactions are induced by the oxidative decomposition of the electrolyte at the positive electrode.
JOURNAL OF POWER SOURCES
(2023)
Article
Oncology
Trang Le, Sumeyye Su, Arkadz Kirshtein, Leili Shahriyari
Summary: This study developed a data-driven mathematical model to study the interactions between immune cells and the osteosarcoma microenvironment, finding that the relative abundance of different immune cell populations has varying effects on tumor growth.
Review
Biochemistry & Molecular Biology
Yi Zhao, Benzheng Zhang, Qianqian Zhang, Xiaowei Ma, Helin Feng
Summary: Osteosarcoma is the most common primary bone tumor in children and adolescents, known for its aggressive nature and tendency to metastasize to the lungs. The tumor microenvironment, particularly tumor-associated macrophages, plays a crucial role in promoting tumor growth while inhibiting metastasis in osteosarcoma. Research on the mechanisms of tumor-associated macrophages in osteosarcoma development and immunotherapy for osteosarcoma is of significant interest.
JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B
(2021)
Article
Materials Science, Composites
Daniel P. Pulipati, Pruthul Kokkada Ravindranath, David A. Jack
Summary: This study presents a methodology to measure bondline thickness using ultrasound testing. A portable ultrasound scanner was used to obtain data and analyze the bondline thickness. The results were validated against x-ray computed tomography reconstructions, demonstrating the accuracy of ultrasound testing.
POLYMER COMPOSITES
(2023)
Correction
Chemistry, Multidisciplinary
Zhennan Zhao, Pan Gao, Li Ma, Tianfeng Chen
Summary: The study presents a highly X-ray sensitive iridium prodrug for visualized tumor radiochemotherapy.
Article
Engineering, Biomedical
Letitia K. Chim, Isabelle L. Williams, Caleb J. Bashor, Antonios G. Mikos
Summary: The tumor microenvironment consists of physical cues and biochemical signals that facilitate cancer progression. Tumor-associated macrophages are of interest due to their pro-tumorigenic functions. Three-dimensional models of tumors mimic the microenvironment and can be used to study the effects of macrophages and mechanical properties on cancer.
Article
Chemistry, Analytical
Yves Kayser, Janos Osan, Philipp Hoenicke, Burkhard Beckhoff
Summary: Understanding the distribution and composition of PM in air is crucial for identifying sources and studying environmental impacts. TXRF has sensitivity in element-sensitive investigation, but linear calibration limits must be considered for accurate quantification.
ANALYTICA CHIMICA ACTA
(2022)
Article
Geochemistry & Geophysics
Nolwenn Le Gall, Fabio Arzilli, Giuseppe La Spina, Margherita Polacci, Biao Cai, Margaret E. Hartley, Nghia T. Vo, Robert C. Atwood, Danilo Di Genova, Sara Nonni, Edward W. Llewellin, Mike R. Burton, Peter D. Lee
Summary: The study investigated the impact of crystallisation kinetics on lava flow behavior by using real-time synchrotron X-ray microtomography to observe the nucleation and growth of clinopyroxene and plagioclase in oxidised, nominally anhydrous basaltic magma. It was found that under continuous cooling, the onset of key transitions in lava hardening occurred within a shorter timeframe, demonstrating the potential of real-time synchrotron X-ray tomography in analyzing the solidification history of basaltic lavas.
EARTH AND PLANETARY SCIENCE LETTERS
(2021)
Article
Construction & Building Technology
Fan Zheng, Rongrong Jiang, Biqin Dong, Shuxian Hong, Yuanyuan Zhang, Guohao Fang, Yanshuai Wang
Summary: This study monitored the capillary absorption process of cement pastes with different crack sizes using X-ray radiography. It was found that cracks provided a direct path for water diffusion and made the water distribution uniform. As the crack width decreased, water content increased, and the influence of cracks decreased with the progress of the water absorption process.
CONSTRUCTION AND BUILDING MATERIALS
(2022)
Article
Materials Science, Multidisciplinary
Shahabeddin Dayani, Henning Markoetter, Jonas von Krug von Nidda, Anita Schmidt, Giovanni Bruno
Summary: This paper investigates the overdischarge phenomenon in lithium-ion cells, focusing on the behavior of copper dissolution and deposition. The concentration of dissolved and deposited copper is quantified using nondestructive imaging, revealing a nonuniform distribution pattern for copper deposition on the cathode. The research provides insights for safer battery cell design.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Article
Endocrinology & Metabolism
Nicholas A. Mignemi, Masato Yuasa, Courtney E. Baker, Stephanie N. Moore, Rivka C. Ihejirika, William K. Oelsner, Christopher S. Wallace, Toshitaka Yoshii, Atsushi Okawa, Alexey S. Revenko, A. Robert MacLeod, Gourab Bhattacharjee, Joey V. Barnett, Herbert S. Schwartz, Jay L. Degen, Matthew J. Flick, Justin M. Cates, Jonathan G. Schoenecker
JOURNAL OF BONE AND MINERAL RESEARCH
(2017)
Article
Orthopedics
Michael A. Benvenuti, Thomas J. An, Megan E. Mignemi, Jeffrey E. Martus, Isaac P. Thomsen, Jonathan G. Schoenecker
JOURNAL OF PEDIATRIC ORTHOPAEDICS
(2019)
Article
Orthopedics
Jennifer M. Bauer, Christopher M. Stutz, Jonathan G. Schoenecker, Steven A. Lovejoy, Gregory A. Mencio, Jeffrey E. Martus
JOURNAL OF PEDIATRIC ORTHOPAEDICS
(2019)
Article
Orthopedics
William K. Oelsner, Stephen M. Engstrom, Michael A. Benvenuti, Thomas J. An, Richard A. Jacobson, Gregory G. Polkowski, Jonathan G. Schoenecker
JOURNAL OF ARTHROPLASTY
(2017)
Article
Immunology
James B. Wood, Cheryl Sesler, Donald Stalons, Elena Grigorenko, Jonathan G. Schoenecker, C. Buddy Creech, Isaac P. Thomsen
OPEN FORUM INFECTIOUS DISEASES
(2018)
Article
Multidisciplinary Sciences
Jonathan G. Schoenecker
Article
Multidisciplinary Sciences
Emilie Amaro, Stephanie N. Moore-Lotridge, Bronson Wessinger, Michael A. Benvenuti, Thomas J. An, William K. Oelsner, Gregory G. Polkowski, Jonathan G. Schoenecker
Summary: This study examined the longitudinal changes in albumin and FAR in healthy patients following total knee arthroplasty (TKA) and found that albumin levels follow a predictable postoperative decline that inversely correlates with CRP. Preoperative FAR strongly correlated with postoperative week 2 values, while there was a weak positive correlation between age-adjusted CCI and pre-operative FAR in patients undergoing primary TKA.
Article
Engineering, Biomedical
Lauren A. Boller, Stefanie M. Shiels, David C. Florian, Sun H. Peck, Jonathan G. Schoenecker, Craig Duvall, Joseph C. Wenke, Scott A. Guelcher
Summary: This study explores the effects of nHA dispersed in polymeric scaffolds on bone regeneration, finding that nHA has a dose-dependent impact on osteogenesis and promotes new bone formation in a site-specific manner. The findings provide new insights into designing synthetic bone grafts for complex fracture cases.
ACTA BIOMATERIALIA
(2021)
Article
Orthopedics
Andrew B. Rees, Jacob D. Schultz, Lucas C. Wollenman, Stephanie N. Moore-Lotridge, Jeffrey E. Martus, Jonathan G. Schoenecker, Gregory A. Mencio
Summary: The study found that the rate of iatrogenic ulnar nerve injury during cross-pinning treatment for SCHFs was 0.43%, significantly lower than previous estimates. Most cases of ulnar nerve injury resolved within 15 weeks of follow-up.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2022)
Article
Medicine, Research & Experimental
Breanne H. Y. Gibson, Colby C. Wollenman, Stephanie N. Moore-Lotridge, Patrick R. Keller, J. Blair Summitt, Alexey R. Revenko, Matthew J. Flick, Timothy S. Blackwell, Jonathan G. Schoenecker
Summary: Severe injury induces systemic inflammatory response syndrome (SIRS), with early activation of plasmin playing a key role in driving SIRS. Plasmin activation is associated with injury severity, SIRS, coagulopathy, and mortality. Targeted inhibition of plasmin activation may be effective in limiting both hemorrhage and tissue-damaging inflammation after injury.
Review
Engineering, Biomedical
Marc Bohner, Yassine Maazouz, Maria-Pau Ginebra, Pamela Habibovic, Jonathan G. Schoenecker, Howard Seeherman, Jeroen J. J. P. van den Beucken, Frank Witte
Summary: This study aims to evaluate the hypothesis that sustained local ionic homeostatic imbalance (SLIHI) created by mineral formation during tissue calcification modulates inflammation to trigger heterotopic ossification (HO), and to provide insights for the design of cell-free, drug-free osteoinductive bone graft substitutes.
ACTA BIOMATERIALIA
(2022)
Article
Surgery
Anthony Riccio, Todd J. Blumberg, Keith D. Baldwin, Jonathan G. Schoenecker
Summary: In pediatric Monteggia fractures, the presence of residual radiocapitellar subluxation after ulnar reduction requires a more aggressive approach such as intramedullary fixation. This method can restore and maintain ulnar length in younger children, with benefits of shorter anesthetic time and less scarring compared to open reduction and plate fixation.
JBJS ESSENTIAL SURGICAL TECHNIQUES
(2021)
Article
Hematology
Breanne H. Y. Gibson, Matthew T. Duvernay, Stephanie N. Moore-Lotridge, Matthew J. Flick, Jonathan G. Schoenecker
RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS
(2020)
Article
Orthopedics
Jennifer M. Bauer, Marjorie P. Butler, Perry L. Schoenecker, Jonathan G. Schoenecker
TECHNIQUES IN ORTHOPAEDICS
(2020)
Article
Hematology
Guojie Wu, Blake A. Mazzitelli, Adam J. Quek, Matthew J. Veldman, Paul J. Conroy, Tom T. Caradoc-Davies, Lisa M. Ooms, Kellie L. Tuck, Jonathan G. Schoenecker, James C. Whisstock, Ruby H. P. Law