Article
Chemistry, Multidisciplinary
Jung-Hwan Jo, Jin-Woo Chung
Summary: This study found that the prevalence of TMD was higher in women than men in Korea, with women showing more myogenous pain, subjective insomnia, and pain intensity. Gender was related to the number of positive muscle palpation and maximum mouth opening, while pain intensity was associated with the number of systemic comorbidities.
APPLIED SCIENCES-BASEL
(2021)
Article
Dentistry, Oral Surgery & Medicine
Christian Hirsch, Oliver Schierz, Antje Koerner, Wieland Kiess, Ronald Biemann, Annett Schrock, Jens Christoph Turp
Summary: This study investigated the association between sex hormone levels (DHEA-S, SHBG, and TT) and TM pain in male adolescents. The results showed that lower levels of serum free TT and DHEA-S were associated with increased TM pain in more developed male adolescents.
JOURNAL OF ORAL REHABILITATION
(2023)
Article
Dentistry, Oral Surgery & Medicine
Miriam Shalish, Avi Leibovich, Avraham Zakuto, Hulio Slutzky, Stella Chaushu, Galit Almoznino
Summary: This case-control study aims to analyze the associations between orthodontic treatment and TMD diagnosis and disease characteristics.
JOURNAL OF ORAL REHABILITATION
(2023)
Article
Health Care Sciences & Services
Andreas Konrad, Kazuki Kasahara, Riku Yoshida, Yuta Murakami, Ryoma Koizumi, Masatoshi Nakamura
Summary: This study aimed to investigate the repeated application of PPT tests in different muscles. The results showed a significant increase in PPT in the elbow flexors and knee extensors, starting from the eighth and ninth assessments, respectively. However, there was no significant change in the ankle plantar flexor muscles. Based on these findings, it is recommended to perform between two and seven PPT assessments to avoid overestimation.
Article
Cell Biology
Claudia Vinciguerra, Salvatore Iacono, Liliana Bevilacqua, Annamaria Landolfi, Giuseppe Piscosquito, Federica Ginanneschi, Giuseppe Schiro, Vincenzo Di Stefano, Filippo Brighina, Paolo Barone, Carmela Rita Balistreri
Summary: The prevalence, onset, pathophysiology, and clinical course of neuromuscular disorders (NMDs) can differ significantly between males and females. Genetic inheritance plays a familiar role in sex differences in NMDs, but hormonal and genetic factors can also influence the clinical presentation and severity of acquired forms. This review summarizes the sex-related differences in both acquired and inherited NMDs, highlighting the distinctive biological roles of these factors.
MECHANISMS OF AGEING AND DEVELOPMENT
(2023)
Article
Medicine, General & Internal
Liliana Szyszka-Sommerfeld, Magdalena Sycinska-Dziarnowska, Agata Budzynska, Krzysztof Wozniak
Summary: This study assessed masticatory muscle electromyographic (EMG) activity in children diagnosed with pain-related temporomandibular disorders (TMD-P) and awake bruxism (AB), as well as the diagnostic value of surface electromyography (sEMG) in diagnosing TMD-P in subjects with AB. The results showed statistically significant intergroup differences in the activity of the anterior temporal (TA) and masseter (MM) muscles at rest and during maximum voluntary clenching (MVC). sEMG demonstrated moderate accuracy in discriminating between TMD-P and non-TMD children.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Psychiatry
Katie Benitah, Ashley N. Siegel, Orly Lipsitz, Nelson B. Rodrigues, Shakila Meshkat, Yena Lee, Rodrigo B. Mansur, Flora Nasri, Leanna M. W. Lui, Roger S. McIntyre, Joshua D. Rosenblat
Summary: A systematic review of published clinical studies found no significant differences in the antidepressant response, tolerability, or safety of ketamine between males and females in the treatment of mood disorders.
PSYCHIATRY RESEARCH
(2022)
Review
Biochemistry & Molecular Biology
Mariana Lapo Pais, Joao Martins, Miguel Castelo-Branco, Joana Goncalves
Summary: Tryptophan is an essential amino acid that plays a role in neuropsychiatric diseases. Women have a higher susceptibility to serotonin alterations due to changes in tryptophan levels, leading to a female sex bias in neuropsychiatric diseases. Further research is needed on the impact of diet and sex steroids on tryptophan metabolism.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Dentistry, Oral Surgery & Medicine
Sylwia Orzeszek, Marta Waliszewska-Prosol, Dominik Ettlin, Piotr Seweryn, Marcin Straburzynski, Paolo Martelletti, Andrej Jenca, Mieszko Wieckiewicz
Summary: This systematic review aims to determine the effectiveness of occlusal splints (OSs) in the treatment of orofacial myalgia and myofascial pain (MP). Thirteen studies were included in the review, and the results showed insufficient evidence to support the advantage of OS therapy over other interventions or no treatment. Further clinical studies with larger sample sizes and controls are needed to improve the quality of research in this area.
Review
Clinical Neurology
Liliana Szyszka-Sommerfeld, Magdalena Sycinska-Dziarnowska, Gianrico Spagnuolo, Krzysztof Wozniak
Summary: Temporomandibular disorders (TMD) are prevalent painful conditions affecting the orofacial region. Surface electromyography (sEMG) is a useful method for assessing patients with TMD-P. Results showed differences in masticatory muscle activity (MMA) between TMD-P patients and healthy controls. The diagnostic efficacy of sEMG in TMD-P remains unclear.
FRONTIERS IN NEUROLOGY
(2023)
Article
Medicine, General & Internal
Marcos Iglesias-Peon, Juan Mesa-Jimenez, Cesar Fernandez-de-las-Penas, Jorge Rojas-Garcia, Daiana Priscila Rodrigues-de-Souza, Francisco Alburquerque-Sendin
Summary: The study investigated the validity of the Isometric Contraction Test (ICTest) for diagnosing muscular Temporomandibular Disorders (TMD). The ICTest showed high specificity but lower sensitivity, especially for different types of myalgia.
Article
Biochemistry & Molecular Biology
Glauce Crivelaro Nascimento, Gabrielle Jacob, Bruna Araujo Milan, Gabrielli Leal-Luiz, Bruno Lima Malzone, Airam Nicole Vivanco-Estela, Daniela Escobar-Espinal, Fernando Jose Dias, Elaine Del-Bel
Summary: The pathophysiologic mechanisms of the lateral pterygoid muscles (LPMs) and the trigeminal system related to Parkinson's Disease (PD)-induced orofacial manifestations were investigated. The study found that hemiparkinsonism increased slow skeletal myosin fibers in the LPMs, while in dyskinetic rats, these fibers decreased in the contralateral side of the lesion. Activation of the spinal trigeminal nucleus may be associated with orofacial sensorial impairment in Parkinsonian rats, while a fatigue profile on LPMs is suggested in L-DOPA-induced dyskinesia when the motor and facial nucleus are activated.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Dentistry, Oral Surgery & Medicine
Marcelo Kreiner, Jesus Viloria
Summary: This study developed and tested a novel neural network for diagnosing orofacial pain and TMD. The results showed that the artificial intelligence had higher diagnostic accuracy than general dental clinicians, particularly in cases of non-dental and referred orofacial pain. This study demonstrates for the first time that an artificial neural network can assist in diagnosing various types of orofacial pain and dysfunction, including TMD, neuropathic pain, neurovascular pain, and referred cardiac pain, and may even play a life-saving role in some cases.
JOURNAL OF ORAL REHABILITATION
(2022)
Article
Psychiatry
Dorte M. Christiansen, Margaret M. McCarthy, Mary V. Seeman
Summary: Sex differences are prevalent in multiple mental disorders, including prevalence, symptom profile, age of onset, comorbidities, functional impairment, prognosis, and treatment response. This conceptual article discusses theories and empirical studies of sex- and gender-related influences in mental health, with a focus on autism spectrum disorder, eating disorders, and posttraumatic stress disorder. Gender differences not only exist between men and women, but also within each sex, due to variations in genes, hormone levels, self-perceptions, trauma experiences, and interpersonal relationships. A conceptual diatheses-stress model is proposed to understand and predict sex/gender differences in mental disorders.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Multidisciplinary Sciences
Abdelrahman M. Alhilou, Akiko Shimada, Camilla I. Svensson, Peter Svensson, Malin Ernberg, Brian E. Cairns, Nikolaos Christidis
Summary: Women exhibited a greater magnitude of NGF-induced mechanical sensitization compared to men, which was associated with nerve fibers expression of NMDA-receptors. These findings suggest that increased peripheral NMDA-receptor expression may be associated with masseter muscle pain sensitivity in women.
SCIENTIFIC REPORTS
(2021)
Article
Dentistry, Oral Surgery & Medicine
M. Bristela, M. Schmid-Schwap, J. Eder, G. Reichenberg, M. Kundi, E. Piehslinger, S. Robinson
CLINICAL ORAL INVESTIGATIONS
(2017)
Article
Dentistry, Oral Surgery & Medicine
Martina Schmid-Schwap, Margit Bristela, Elisabeth Pittschieler, Astrid Skolka, Pavol Szomolanyi, Michael Weber, Eva Piehslinger, Siegfried Trattnig
CLINICAL ORAL INVESTIGATIONS
(2014)
Article
Dentistry, Oral Surgery & Medicine
Martina Schmid-Schwap, Alexander Franz, Franz Koenig, Margit Bristela, Trevor Lucas, Eva Piehslinger, David C. Watts, Andreas Schedle
Review
Dentistry, Oral Surgery & Medicine
Martina Schmid-Schwap, Alexandra Graf, Angela Preinerstorfer, David C. Watts, Eva Piehslinger, Andreas Schedle
Article
Radiology, Nuclear Medicine & Medical Imaging
Martina Schmid-Schwap, Wolfgang Drahanowsky, Margit Bristela, Michael Kundi, Eva Piehslinger, Soraya Robinson
EUROPEAN RADIOLOGY
(2009)
Article
Dentistry, Oral Surgery & Medicine
Martina Schmid-Schwap, Valentin Rousson, Karin Vornwagner, Siegward D. Heintze
JOURNAL OF PROSTHETIC DENTISTRY
(2009)
Article
Radiology, Nuclear Medicine & Medical Imaging
Elisabeth Pittschieler, Pavol Szomolanyi, Martina Schmid-Schwap, Michael Weber, Monika Egerbacher, Hannes Traxler, Siegfried Trattnig
MAGNETIC RESONANCE IMAGING
(2014)
Article
Dentistry, Oral Surgery & Medicine
Jaryna Eder, Zbynek Tonar, Martina Schmid-Schwap, Margit Bristela, Astrid Skolka, Hannes Traxler, Eva Piehslinger, Monika Egerbacher, Siegfried Trattnig, Kirsti Witter
JOURNAL OF ORAL & FACIAL PAIN AND HEADACHE
(2018)
Article
Radiology, Nuclear Medicine & Medical Imaging
Margit Bristela, Astrid Skolka, Jaryna Eder, Pavol Szomolanyi, Michael Weber, Eva Piehslinger, Martina Schmid-Schwap, Siegfried Trattnig
MAGNETIC RESONANCE IMAGING
(2019)
Article
Multidisciplinary Sciences
Benedikt Sagl, Martina Schmid-Schwap, Eva Piehslinger, Michael Kundi, Ian Stavness
Summary: This study presents a novel in silico approach to investigate the impact of wear facet inclination and position on temporomandibular joint (TMJ) stress. Simulation results suggest that an increase in inclination leads to a decrease in TMJ loading, while wear facet position may be more relevant for TMJ loading. The findings provide insights into the effect of tooth morphology on TMJ loading during bruxism.
JOURNAL OF ADVANCED RESEARCH
(2022)
Article
Engineering, Biomedical
Benedikt Sagl, Martina Schmid-Schwap, Eva Piehslinger, Xiaohui Rausch-Fan, Ian Stavness
Summary: This study investigated the impact of food bolus variables on mechanical TMJ loading, finding that smaller and softer food boluses lead to reduced TMJ loading. The results support current guidelines on bolus modifications and suggest potential guidelines for bolus positioning that could be validated in future clinical trials. This in silico investigation of dynamic chewing with detailed TMJ stress helps to enhance confidence in TMD self-management recommendations and may help in reducing pain levels for patients.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2021)
Article
Public, Environmental & Occupational Health
Margit Bristela, Astrid Skolka, Martina, Schmid-Schwap, Eva Piehslinger, Alexander Indra, Guenther Wewalka, Fritz Stauffer
GMS HYGIENE AND INFECTION CONTROL
(2012)
Article
Dentistry, Oral Surgery & Medicine
Martina Schmid-Schwap, Alexander Franz, Martin Krainhoefner, Franz Koenig, Gerald Krennmair, Andreas Schedle
INTERNATIONAL JOURNAL OF PROSTHODONTICS
(2007)
Article
Dentistry, Oral Surgery & Medicine
Gerald Krennmair, Martin Krainhoefner, Martina Schmid-Schwap, Eva Piehslinger
INTERNATIONAL JOURNAL OF ORAL & MAXILLOFACIAL IMPLANTS
(2007)