Article
Chemistry, Multidisciplinary
Jai Devi, Sushila Pachwania, Deepak Kumar, Deepak Kumar Jindal, Suraya Jan, Ashutosh K. Dash
Summary: Organotin(IV) complexes have been synthesized and structurally characterized in this study. The synthesized complexes exhibited significant antimicrobial and cytotoxic activities, with complex 20 showing the highest antimicrobial activity, and complex 11 demonstrating the most efficient cytotoxic activity against tested human cancerous cell lines.
RESEARCH ON CHEMICAL INTERMEDIATES
(2022)
Article
Biochemistry & Molecular Biology
Ivan V. Smolyaninov, Andrey I. Poddel'sky, Daria A. Burmistrova, Yulia K. Voronina, Nadezhda P. Pomortseva, Maria A. Polovinkina, Nailya R. Almyasheva, Maria A. Zamkova, Nadezhda T. Berberova, Igor L. Eremenko
Summary: A series of novel di- and triorganotin(IV) complexes were synthesized and characterized. The compounds were evaluated for their antioxidant and antiproliferative activities. The results showed that the compounds with free phenol or catechol fragments exhibited higher antioxidant and antiproliferative activities, compared to those with tridentate O,N,S-coordinated ligands. Furthermore, these compounds were found to possess antioxidative effects on promoted oxidative damage of DNA and rat liver in vitro.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Inorganic & Nuclear
Tushar S. Basu Baul, Bietlaichhai Hlychho, Maheswara Rao Addepalli, Sajal Kundu, Dick de Vos, Anthony Linden
Summary: Three polynuclear organotin(IV) derivatives, denoted as [n-Bu3Sn(HL)]n 1, [Ph3Sn(HL)]n 2, and [n-Bu2Sn(HL)2]2 3, have been successfully synthesized by reacting 2-((E)-(4-hydroxy-3-((E)-((4-(methoxycarbonyl)phenyl)imino)methyl)phenyl)diazenyl)benzoic acid (H'HL) with (n-Bu3Sn)2O, Ph3SnOH, and n-Bu2SnO, respectively. The structures of 1-3 were fully characterized and their molecular and crystal structures were determined by single-crystal X-ray diffraction analysis. Compound 1 is a one-dimensional coordination polymer, whereas compound 2 is a one-dimensional coordination polymer with a zwitterionic form of the azo ligand. Compound 3 crystallizes as discrete centrosymmetric dinuclear entities with a heptacoordinated Sn(IV) center in a distorted pentagonal bipyramidal coordination geometry.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Gelen Gomez-Jaimes, Iran Rojas Leon, Rodolfo Martinez Romero, Hiram I. Beltran, Braulio Rodriguez-Molina, Wolf Hiller, Klaus Jurkschat, Iran F. Hernandez, Herbert Hoepfl
Summary: The synthesis and characterization of six dinuclear organotin building blocks were reported, with the crystal and molecular structures of BD2 determined by single-crystal X-ray diffraction analysis, revealing the formation of molecular strands. Additionally, a related molecular macrocyclic structure was generated through reaction and DFT calculations were performed to study the molecular conformers of M1.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Analytical
Cornelia Rasmussen, David W. Hoffman
Summary: This paper introduces a novel nuclear magnetic resonance (NMR) tool for determining position-specific carbon isotope ratios within complex organic molecules. The method allows for the measurement of isotope ratios in samples containing impurities that overlap with the signals of interest. The method was validated using reference materials and successfully applied to determine position-specific isotope ratios in real samples.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Medicinal
Jingmin Cui, Yan Sun, Linqing Wang, Qin Miao, Wenqiang Tan, Zhanyong Guo
Summary: A series of l-arginine Schiff base acylated chitosan derivatives were successfully prepared to enhance the antioxidant and antimicrobial activities. Some compounds showed promising activities, indicating potential for further development and utilization as antioxidants and antimicrobial agents.
Article
Chemistry, Applied
Desislav Dinev, Katya B. Popova, Tanya Zhivkova, Lora Dyakova, Abedullkader Abudalleh, Radostina Alexandrova, Daniela C. Culita, Teodora Mocanu, Catalin Maxim, Gabriela Marinescu
Summary: Two new families of Cu(II) and Co(II) mononuclear complexes with mixed ligands were successfully synthesized and characterized. Biological evaluation showed that these complexes exhibit cytotoxic effects on HeLa and LSR-SF-SR cells.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
Article
Chemistry, Physical
Har Lal Singh, Naveen Dhingra, Sunita Bhanuka
Summary: A series of main group metal and metalloid complexes with bidentate Schif bases derived from amino acids were synthesized and characterized. The complexes showed different geometrical arrangements and were tested for antibacterial efficacy. The R3Sn(IV) compounds exhibited the highest antibacterial activity and could serve as potential leads for novel antibacterial agents.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Chemistry, Multidisciplinary
Satheesh Chikkanahalli Eranna, Raghavendra Kumar Panchangam, Jayanna Kengaiah, Suchetan Parameshwar Adimule, Sabine Foro, Devaraju Sannagangaiah
Summary: New Schiff bases with amide and phenolic groups were synthesized and characterized. These compounds showed procoagulant activity and some exhibited specific anticoagulant and antiplatelet aggregation activities, making them potential candidates for new anticoagulant and antiplatelet agents.
MONATSHEFTE FUR CHEMIE
(2022)
Article
Chemistry, Organic
Yifan Mao, Stephanie Davis, Lin Pu
Summary: The dynamic covalent chemistry of imines is used to synthesize an unsymmetric (C-1) chiral macrocycle from the reaction of an unsymmetric (C-1) chiral dialdehyde with lysine. The enantioselectivity is enhanced in the presence of Zn2+. The resulting compound is a highly selective fluorescent probe for lysine.
Article
Chemistry, Inorganic & Nuclear
Congjian Ni, Ziyuan Pang, Yuhang Qiao, Pingping Guo, Xiaoli Ma, Zhi Yang
Summary: Organic aluminum compounds derived from halogen-substituted Schiff bases have emerged as a research hotspot in the development of green chemistry. These compounds, characterized by twisted six-membered ring structures, show excellent catalytic performance in the hydroboration of aldehydes and ketones.
INORGANICA CHIMICA ACTA
(2022)
Review
Chemistry, Medicinal
Wardha Zafar, Sajjad H. Sumrra, Zahid H. Chohan
Summary: Clinical reports have emphasized the increasing threat of multidrug resistance due to antibiotic resistance. Research has shown that organic compounds now require metal ions for bio-transformation in order to enhance their potentiality against resistance. Metal based drugs have played an imperative role in developing new strategies with significant biological activity, safety, and efficacy. In recent years, metal based compounds have been of great interest for treating various diseases, filling the gap left by conventional methodologies.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2021)
Article
Microbiology
Paola Borrego-Munoz, Diego Cardenas, Felipe Ospina, Ericsson Coy-Barrera, Diego Quiroga
Summary: The synthesis of 48 enamine-type Schiff bases derived from three amino acids was carried out, and their antifungal activity and protective effect against Fusarium oxysporum were evaluated. The results showed that the size of the substituent on the acetylacetone derivatives and the electronic character on the cyclohexane-3-one fragment influenced the antifungal effect. The structure-activity relationship of the compounds was established using atom-based 3D-QSAR models, which provided information about the structural requirements for enhancing their antifungal activity.
Article
Chemistry, Multidisciplinary
Lisanne Sellies, Ruud L. E. G. Aspers, Martin C. Feiters, Floris P. J. T. Rutjes, Marco Tessari
Summary: In recent years, the scope of non-hydrogenative parahydrogen hyperpolarization (nhPHIP) techniques has been expanding, allowing for the detection and quantification of unmodified alpha-amino acids in complex mixtures. This method has shown great potential as demonstrated in human urine samples.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Biochemistry & Molecular Biology
Aikaterini A. Zompra, Styliani A. Chasapi, Evdokia C. Karagkouni, Eugenia Karamouzi, Panagiotis Panopoulos, Georgios A. Spyroulias
Summary: The study focused on analyzing the overall NMR metabolic profile of sea buckthorn berries grown in an organic orchard in Meteora, Greece, and validated the quality characteristics of osmotic processed berries compared to fresh fruit. The bioactive metabolites of sea buckthorn berries were elucidated through sophisticated high-resolution NMR spectroscopy, revealing a variety of lipophilic and polar compounds. This approach can be used for simultaneous profiling and quality assessment of fresh food using different preservation methods.
Article
Crystallography
Juan Saulo Gonzalez-Gonzalez, Ana Maria Monserrat Martinez-Santiago, Francisco Javier Martinez-Martinez, Maria Jose Emparan-Legaspi, Armando Pineda-Contreras, Marcos Flores-Alamo, Hector Garcia-Ortega
Article
Ophthalmology
Pedro Javier Salas-Ambrosio, Maria Josefa Bernad-Bernad, Monica Anayantzin Linares-Alba, Rodrigo Garcia-Santisteban, Luis Angel Tonix-Aburto, Guadalupe Jocelyn Ornelas-Lobato, Isabel Gracia-Mora, Marisol Rivera-Huerta, Francisco Sanchez-Bartez, Hector Rico-Morales, Gustavo Adolfo Garcia-Sanchez
Summary: The study evaluated the safety and toxicity of a novel liposome-encapsulated rapamycin formulation in animal ocular administration. Results indicated no significant toxicity with SCJ or IVT injections, making it a potential alternative immunosuppressive treatment for immune-mediated eye pathologies.
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS
(2021)
Article
Chemistry, Physical
Javier Ordonez-Hernandez, Rafael Arcos-Ramos, Violeta Alvarez-Venicio, Vladimir A. Basiuk, Oscar Gonzalez-Antonio, Marcos Flores-Alamo, Hector Garcia-Ortega, Norberto Farfan, Maria del Pilar Carreon-Castro
Summary: Chromophoric coumarin-BODIPY derivatives bridged by an ethynyl pi-bridge were studied as supramolecular building blocks for organic semiconducting solids. The molecular properties and supramolecular self-assembly can be directed by modifying the ethynyl-aryl pi-bridge and intermolecular interactions. Frontier orbital energy changes depending on chemical environment were analyzed for potential semiconductor applications.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Biochemistry & Molecular Biology
Emilio Iturriaga-Goyon, Oscar Vivanco-Rojas, Fatima Sofia Magana-Guerrero, Beatriz Buentello-Volante, Ilse Castro-Salas, Jose Eduardo Aguayo-Flores, Isabel Gracia-Mora, Marisol Rivera-Huerta, Francisco Sanchez-Bartes, Yonathan Garfias
Summary: The study demonstrated that AS1411 inhibits retinal neovascularization by reducing cell proliferation, migration, and tube formation, as well as decreasing NCL phosphorylation levels. This suggests that AS1411 could potentially serve as a novel anti-angiogenic treatment targeting pathological angiogenesis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Multidisciplinary
Antonio Reina, Hector Garcia-Ortega, Jesus Gracia-Mora, Armando Marin-Becerra, Miguel Reina
Summary: Educational games play an important role in chemistry courses by providing a fun and enjoyable learning environment to help students consolidate basic concepts and increase scientific knowledge.
JOURNAL OF CHEMICAL EDUCATION
(2022)
Article
Chemistry, Multidisciplinary
Antonio Reina, Hector Garcia-Ortega, Luis Felipe Hernandez-Ayala, Itzel Guerrero-Rios, Jesus Gracia-Mora, Miguel Reina
Summary: CADMIO is a peer-reviewed YouTube channel with over 60 videos in Spanish, 2,550 subscribers, and 6,000 hours of views in the first year. It focuses on introductory and advanced inorganic chemistry topics, providing clear explanations, methodologies to enhance problem-solving skills, and a variety of exercises for students. The positive response has led to its establishment as a Social Service program in Mexico, showcasing its effectiveness as a teaching and learning tool.
JOURNAL OF CHEMICAL EDUCATION
(2021)
Article
Chemistry, Multidisciplinary
Hector Garcia-Ortega, Chloe Lhardy, Jesus Gracia-Mora, Armando Marin-Becerra, Miguel Reina, Antonio Reina
Summary: This study presents an educational game called MET-organic, which is used to teach nomenclature and functional group identification in organic chemistry courses. The results show that the game has a positive impact on student learning and engagement.
JOURNAL OF CHEMICAL EDUCATION
(2022)
Article
Chemistry, Multidisciplinary
Juan Saulo Gonzalez-Gonzalez, Miguel Eulalio Valiente Flores, Marcos Flores-Alamo, Elizabeth Macias-Lopez, Francisco Javier Martinez-Martinez, Hector Garcia-Ortega
Summary: Two cocrystals (DHN-INH and DHN-PIR) crystallized in different space groups and connected molecules through different hydrogen bonding patterns. The supramolecular architecture showed different forms in the two cocrystals, with interlinked supramolecular tapes in one and interlinked supramolecular sheets in the other.
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Chloe Lhardy, Hector Garcia-Ortega, Jesus Gracia-Mora, Armando Marin-Becerra, Antonio Reina, Miguel Reina
Summary: Unit Kemps is an engaging and easy-to-play educational game that aims to help students learn physical quantities and differentiate between their properties, units, and symbols. Testing in Mexico showed encouraging results in terms of content, playability, and engagement.
JOURNAL OF CHEMICAL EDUCATION
(2022)
Article
Chemistry, Physical
Edgard Fabian Blanco-Acuna, Hector Garcia-Ortega
Summary: A series of new 2,2'-bis(indolyl)methane-triphenylamine derivatives were synthesized and characterized. These derivatives showed high torsion and intramolecular rotation due to the incorporation of TPA units in the indole fragment and the methylene position of the BIM. Some of the derivatives exhibited solvatochromic behavior and fluorescence in the solid state.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Physical
Edgard Fabian Blanco-Acuna, Luis Antonio Vazquez-Lopez, Laura Gasque, Hector Garcia-Ortega
Summary: This study synthesized three coumarin-triphenylamine chalcone derivatives with push-pull structures by varying the substituent. The compounds showed strong solvatochromism and aggregation-induced emission, indicating potential nonlinear optical properties.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Biochemistry & Molecular Biology
Henry Arceo-Ruiz, Elba Xochitiotzi-Flores, Hector Garcia-Ortega, Norberto Farfan, Rosa Santillan, Susana Rincon, Alejandro Zepeda
Summary: A Co metal-organic framework called Co-MTPhPyP assembled from TPhPyP was successfully synthesized and characterized by various techniques. The Co-MTPhPyP showed promising sorption properties for the removal of Pb(II) and Cu(II) in aqueous solution. The kinetic studies indicated a maximum adsorption capacity of 458.8 mg g(-1) for Pb(II) after 30 minutes of exposure.
Article
Chemistry, Multidisciplinary
Francisco A. Reza-Gonzalez, Emmanuel Villatoro, Mariana M. Reza, Jesus Jara-Cortes, Hector Garcia-Ortega, Edgard F. Blanco-Acuna, Jose G. Lopez-Cortes, Nuria Esturau-Escofet, Alan Aguirre-Soto, Jorge Peon
Summary: This paper presents a study on the photo-induced transformation and two-photon absorption properties of donor-acceptor Stenhouse adducts (DASAs). The results indicate that specific donor groups give these DASAs nonlinear activity, making them suitable for applications in 3D photocontrol, nonlinear lithography, variable depth birefringence, and localized drug delivery schemes.
Article
Chemistry, Multidisciplinary
Juan Saulo Gonzalez-Gonzalez, Salvador Perez-Espinoza, Francisco Javier Martinez-Martinez, Armando Pineda-Contreras, Miguel Angel Canseco-Martinez, Marcos Flores-Alamo, Hector Garcia-Ortega
Summary: This article reports the crystal structure and solid-state characterization of the 1:1 salt piperidinium sulfamethazinate. The salt exhibits hydrogen-bond donors and acceptors, which allows for the formation of supramolecular structures. The crystal structure of the salt reveals proton transfer between sulfamethazine and piperidinium ions, connected by N-H+...O and N-H (+)...N interactions. The self-assembly of sulfamethazine anions forms amine-sulfa C(8) motifs, and the supramolecular architecture displays interconnected sheets.
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY
(2023)
Article
Oncology
Rosa Angelica Castillo-Rodriguez, Guadalupe Palencia, Isabel Anaya-Rubio, Juan Carlos Gallardo-Perez, Dolores Jimenez-Farfan, Angel Escamilla-Ramirez, Sergio Zavala-Vega, Arturo Cruz-Salgado, Claudia Cervantes-Rebolledo, Isabel Gracia-Mora, Lena Ruiz-Azuara, Cristina Trejo-Solis
Summary: Gliomas, particularly glioblastoma multiforme (GBM), are highly aggressive neoplasms affecting the central nervous system. The copper coordination compound Casiopeina III-La (Cas III-La) has shown promising anti-proliferative, pro-apoptotic, and anti-invasive effects on human U373 MG cells, making it a potential agent for treating GBM.
Article
Chemistry, Inorganic & Nuclear
Guojun Hu, Ziyue Deng, Yanwei Wang, Dan Yuan, Yong Zhang, Yingming Yao
Summary: A series of rare-earth metal complexes were synthesized and used as efficient initiators for the polymerization of trimethylene carbonate (TMC) and (L)-lactide ((L)-LA).
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Van Ha Nguyen, John H. K. Yip
Summary: In this study, eight PtII-azulene complexes were synthesized to investigate the effect of metalation on the electronic structures, spectroscopy, and luminescence of organic chromophores. The results showed that the attachment of Pt substituents to azulene affected the HOMOs, LUMOs, and luminescence properties. The study provides insights into the role of metalation in modifying the properties of organic chromophores.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Moon Kedia, Virender Singh, Bhaskaran Shankar, Malaichamy Sathiyendiran
Summary: This study synthesized two types of neutral binuclear metallocycles using a one-pot solvothermal method and characterized their structures. The analysis revealed that these complexes adopt a binuclear heteroleptic cyclic architecture and belong to phosphine oxide donor (P=O)-based supramolecular coordination cyclic complexes.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Radhey S. Srivastava
Summary: This study demonstrates the effectiveness of zero-valent elements as reductants for the deoxydehydration reaction of polyols catalyzed by ONO-pincer ligated molybdenum dioxo. The insolubility and easy separability of the reductants and their oxidized products during the reaction are emphasized. Additionally, the choice of ligand has an impact on the catalytic performance of the reaction.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Hao Zhou, Yajun Sun, Li Deng, Weiran Yang, Yuehui Li
Summary: Efficient Ru-catalyzed hydrogenation of aldehydes was achieved using carbazole-derived phosphine ligands, with the crucial role of N-H moiety in promoting the catalytic reaction. The method was successfully applied in the Co/Ru-catalyzed hydroformylation process, resulting in the production of long-chain alcohols with excellent yields.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Theodor Danescu, Alexandru Lupan, Radu Silaghi-Dumitrescu, R. Bruce King
Summary: The structures and energies of complexes containing (Me2C2N2P)2Ru2(CO)n and (Me2C2N2P)2Fe2(CO)n have been studied. Low-energy structures are characterized by the presence of bridging diazaphospholyl rings, while higher-energy structures involve different ligand structures.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Savannah C. Kapper, Aamani Ponnekanti, Jonas Schaab, Tian-yi Li, Christine L. Chung, Gael Ung, Peter I. Djurovich, Mark E. Thompson
Summary: Organometallic iridium complexes with two cyclometalated ligands and one bis-oxazoline derived ancillary ligand were studied. These complexes have emission spanning across the visible and near-ultraviolet region, with moderate to high photoluminescence quantum yields. The (ppy)2Ir(BOX-CN) complexes were resolved into Delta- and Lambda-diastereomers based on solubility differences.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Zahra Karimi Sangari, Hossein Naeimi
Summary: In this research, a nanostructured CoCuFe2O4 catalyst was prepared using a brief and useful synthetic strategy. This catalyst was used for synthesizing 1,2,4,5-tetrasubstituted imidazole derivatives under ultrasonic irradiation. The approach offers advantages such as high efficiency, short reaction times, simplicity of the reaction medium, accelerated reaction rates, and easier separation and purification of products.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Rukhsana Gul, Wajid Munir, Ebraheem Abdu Musad Saleh, Shaukat Shujah, Muhammad Sirajuddin, Saira Tabassum, Khalil Ur Rehman, Dilfaraz Khan, Sameerah I. Al-Saeedi, Ehab A. Abdelrahman
Summary: Two new Schiff base ligands were synthesized and used to form copper, nickel, and cobalt complexes. The synthesized compounds were characterized and screened for various biological activities. The metal complexes showed better activities in antibacterial, antifungal, antidiabetic, and antioxidant assays.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Review
Chemistry, Inorganic & Nuclear
Ahsan Nazir, Pengwei Huo, Ameena Tur Rasool
Summary: This review explores the potential of g-C3N4-based S-scheme heterojunctions in addressing environmental issues. It summarizes the mechanism and preparation techniques of S-scheme heterojunctions based on g-C3N4, and presents recent studies on their applications in pollutant removal, CO2 reduction, hydrogen production, and bacterial disinfection. The review concludes with an outlook on future challenges for g-C3N4-based S-scheme heterojunctions.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Francois Mazars, Koffi Senam Etse, Guillermo Zaragoza, Lionel Delaude
Summary: The activity of three Pd-PEPPSI catalyst precursors with N-heterocyclic carbene (NHC) ligands derived from caffeine and theophylline in Mizoroki-Heck reactions was tested. The results showed that the catalysts achieved high conversions and yields, especially in the presence of electron-withdrawing substituents.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Bo-Han Wu, Xue Zhou, Lin Liu, Zheng-Bo Han
Summary: Researching carbon dioxide removal from flue gas and natural gas is crucial. Metal-organic frameworks (MOFs) are commonly used in adsorption due to their high surface area, porosity, and chemical properties. An ultra-microporous MOF CPM-20(Co) with mixed ligand was synthesized using inexpensive ligands. The material exhibited high selectivities and low regenerative energy, making it a promising option for CO2 separation in industries.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)