Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 79, Issue 15, Pages 7232-7238Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo501292q
Keywords
-
Categories
Funding
- NSFC [21102059, 21202064]
- Department of Education of Jiangxi Province [GJJ13245]
- Program for Cultivating Youths of Outstanding Ability in Jiangxi Normal University
Ask authors/readers for more resources
The three-component reactions of enals, electron-deficient alkynes, and hydroxyl-functionalized primary amines for the highly diastereoselective construction of dihydro-3H-benzo[4,5]oxazolo-[3,2-a]pyridines, hexahydropyrido[2,1-b][1,3]oxazines, and tetrahydro2H-oxazolo[3,2-a]pyridines have been achieved. Domino formation of one C-C, two C-N, and one C-O bonds are furnished in these reactions. This bis-annulation protocol allows for the synthesis of fused heterocyclic products of high structural diversity with variation not only of appended fragments but also the ring size of the central backbone.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available